pentobarbital has been researched along with Hemorrhagic Shock in 31 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objectives of this study were (i) to characterize the hemodynamic responses caused by controlled hemorrhage (HEM) in pentobarbital-anesthetized rats, and (ii) to determine the responses elicited by systemic bolus injections of isotonic saline (0." | 3.80 | Hemodynamic responses elicited by systemic injections of isotonic and hypertonic saline in hemorrhaged rats. ( Johnson, AK; Lewis, SJ; Whalen, EJ, 2014) |
| " Isoflurane (ISO), ketamine-xylazine (KX), or pentobarbital (PEN) with or without buprenorphine were administered before scald-burn in 72 rats that were euthanized without anesthesia by decapitation after 24 h and compared with unburned shams." | 3.76 | Impact of anesthesia, analgesia, and euthanasia technique on the inflammatory cytokine profile in a rodent model of severe burn injury. ( Al-Mousawi, AM; Branski, LK; Herndon, DN; Jeschke, MG; Kraft, R; Kulp, GA; Mecott, GA; Williams, FN, 2010) |
| "Depth of hypotension is more important than duration in causing intrinsic cardiac dysfunction." | 1.30 | Heart function after severe hemorrhagic shock. ( Barbee, RW; Kline, JA; Lopaschuk, GD; Thornton, LR; Watts, JA, 1999) |
| "In pentobarbital-treated animals, regardless of the extent of heparinization, consistent translocation to both MLN and distant organs occurred when shock was prolonged for 90 min, and assessment of translocation was made 24 hr after reinfusion of shed blood." | 1.29 | Reevaluation of the linkage between acute hemorrhagic shock and bacterial translocation in the rat. ( Chen, CY; Cocanour, CS; LaRocco, MT; Miller, TA; Myers, SI; Reed, RL; Rodriguez, LF; Russell, DH; Smith, GS, 1993) |
| "It has been suggested that acute respiratory distress syndrome (ARDS) is induced by a cybernetic imbalance of the central nervous system secondary to alarm reaction-provoked intravascular coagulation into cerebral microvessels." | 1.27 | Acute respiratory distress syndrome (ARDS): the prophylactic effect of neurodepressant agents. ( de Oliveira Antonio, MP; de Oliveira, GG; Shimano, LT, 1986) |
| "Hemorrhagic shock was produced in dogs by bleeding to a systemic blood pressure of 45 mm Hg for 3 hours, followed by reinfusion of the shed blood." | 1.25 | Pancreatic hypoperfusion and the production of a myocardial depressant factor in hemorrhagic shock. ( Lefer, AM; Spath, JA, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (80.65) | 18.7374 |
| 1990's | 4 (12.90) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (6.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Whalen, EJ | 1 |
| Johnson, AK | 1 |
| Lewis, SJ | 1 |
| INGRAHAM, RC | 3 |
| ROEMHILD, F | 4 |
| GOLDBERG, H | 3 |
| Al-Mousawi, AM | 1 |
| Kulp, GA | 1 |
| Branski, LK | 1 |
| Kraft, R | 1 |
| Mecott, GA | 1 |
| Williams, FN | 1 |
| Herndon, DN | 1 |
| Jeschke, MG | 1 |
| CAIRY, CF | 1 |
| RAMASWAMY, VM | 1 |
| GETTLER, DT | 1 |
| ALLBRITTEN, FF | 1 |
| BAEZ, S | 1 |
| ORKIN, LR | 1 |
| HARDAWAY, RM | 1 |
| JOHNSON, DG | 1 |
| HOUCHIN, DN | 1 |
| JENKINS, EB | 1 |
| BURNS, JW | 1 |
| JACKSON, DR | 1 |
| WIGGERS, HC | 1 |
| Rubányi, G | 1 |
| Kovách, AG | 1 |
| Koltay, E | 1 |
| Nagy-Dóra, T | 1 |
| Balogh, I | 1 |
| Somogyi, E | 1 |
| Myers, SI | 2 |
| Hernandez, R | 1 |
| Miller, TA | 2 |
| Jacinto, SM | 1 |
| Jandhyala, BS | 1 |
| LaRocco, MT | 1 |
| Rodriguez, LF | 1 |
| Chen, CY | 1 |
| Smith, GS | 1 |
| Russell, DH | 1 |
| Cocanour, CS | 1 |
| Reed, RL | 1 |
| Kline, JA | 1 |
| Thornton, LR | 1 |
| Lopaschuk, GD | 1 |
| Barbee, RW | 1 |
| Watts, JA | 1 |
| Vatner, SF | 1 |
| Braunwald, E | 1 |
| de Oliveira, GG | 1 |
| Shimano, LT | 1 |
| de Oliveira Antonio, MP | 1 |
| Adamicza, A | 1 |
| Tárnoky, K | 1 |
| Nagy, A | 1 |
| Nagy, S | 1 |
| Yale, CE | 1 |
| Torhorst, JB | 1 |
| Wilson, JM | 1 |
| Gay, WA | 1 |
| Ebert, PA | 1 |
| Schwarz, HP | 1 |
| Dreisbach, L | 1 |
| Spitzer, JJ | 1 |
| Lefer, AM | 1 |
| Spath, JA | 1 |
| Ritchie, WP | 1 |
| Fischer, RP | 1 |
| Baue, AE | 1 |
| Nara, Y | 1 |
| Lahdensuu, M | 1 |
| Roding, B | 1 |
| Schenk, WG | 1 |
| Mori, S | 1 |
| Simeone, FA | 1 |
| Furneaux, RW | 1 |
| Paton, DM | 1 |
| Gillis, CN | 1 |
| Zierott, G | 1 |
| Rushmer, RF | 1 |
| Watson, N | 1 |
| Harding, D | 1 |
| Baker, D | 1 |
1 review available for pentobarbital and Hemorrhagic Shock
| Article | Year |
|---|---|
Cardiovascular control mechanisms in the conscious state.
Topics: Anesthesia, General; Animals; Cardiovascular Physiological Phenomena; Carotid Sinus; Consciousness; | 1975 |
30 other studies available for pentobarbital and Hemorrhagic Shock
| Article | Year |
|---|---|
Hemodynamic responses elicited by systemic injections of isotonic and hypertonic saline in hemorrhaged rats.
Topics: Animals; Arterial Pressure; Blood Pressure; Hemodynamics; Hemorrhage; Hydrodynamics; Isotonic Soluti | 2014 |
Further observations on the effect of pentobarbital and of an adrenolytic agent upon the survival of animals subjected to a procedure resulting in experimental hemorrhagic shock.
Topics: Adrenergic Antagonists; Animals; Barbital; Hemorrhage; Pentobarbital; Shock; Shock, Hemorrhagic | 1948 |
The effect of pentobarbital anesthesia on the production of irreversible hemorrhagic shock.
Topics: Anesthesia; Anesthesiology; Barbital; Hemorrhage; Humans; Pentobarbital; Shock; Shock, Hemorrhagic | 1947 |
The treatment of impending hemorrhagic shock by means of pentobarbital sedation.
Topics: Anesthesia; Anesthesiology; Barbital; Cardiovascular Diseases; Convulsive Therapy; Hemorrhage; Pento | 1947 |
Impact of anesthesia, analgesia, and euthanasia technique on the inflammatory cytokine profile in a rodent model of severe burn injury.
Topics: Acute-Phase Reaction; Analgesia; Analgesics; Anesthesia, General; Anesthetics; Animals; Buprenorphin | 2010 |
Comparsion of treatments of hemorrhagic shock under deep pentobarbital anesthesia.
Topics: Anesthesia; Animals; Pentobarbital; Shock; Shock, Hemorrhagic | 1962 |
EFFECT OF ALCOHOL INTOXICATION ON THE RESPIRATORY EXCHANGE AND MORTALITY RATE ASSOCIATED WITH ACUTE HEMORRHAGE IN ANESTHETIZED DOGS.
Topics: Alcoholic Intoxication; Anesthesia; Anesthesia, Intravenous; Animals; Dogs; Hemorrhage; Pentobarbita | 1963 |
MICROCIRCULATORY EFFECTS OF ANESTHESIA IN SHOCK.
Topics: Anesthesia; Blood Circulation; Blood Pressure; Capillaries; Cyclopropanes; Ether; Halothane; Hematoc | 1964 |
INFLUENCE OF STRESS ON FIBRINOGEN.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Blood Coagulation Disorders; Coagulants; Cortisone; D | 1964 |
Influence of sodium pentobarbital upon course of events in experimental hemorrhagic shock.
Topics: Barbital; Leadership; Pentobarbital; Shock; Shock, Hemorrhagic; Sodium | 1950 |
Effect of hemorrhagic shock on the performance, O2-consumption, and ultrastructure of isolated rat hearts.
Topics: Animals; Calcium; Energy Metabolism; Female; Lanthanum; Myocardium; Oxygen Consumption; Pentobarbita | 1980 |
Differing effects of anesthetics on splanchnic arterial blood flow during hemorrhagic shock.
Topics: Anesthetics; Animals; Aorta; Blood Pressure; In Vitro Techniques; Mesenteric Artery, Superior; Metho | 1994 |
Comparative evaluation of the acute effects of oxygen free radicals on myocardial contractility in anesthetized dogs with those occurring in the early stages of splanchnic artery occlusion and hemorrhagic shock.
Topics: Animals; Arterial Occlusive Diseases; Dogs; Free Radicals; Hemodynamics; Myocardial Contraction; Oxy | 1994 |
Reevaluation of the linkage between acute hemorrhagic shock and bacterial translocation in the rat.
Topics: Anesthesia; Animals; Bacteria; Bacterial Physiological Phenomena; Blood Flow Velocity; Blood Pressur | 1993 |
Heart function after severe hemorrhagic shock.
Topics: Adenosine Triphosphate; Animals; Coenzyme A; Esters; Heart; Heart Function Tests; Hypnotics and Seda | 1999 |
Acute respiratory distress syndrome (ARDS): the prophylactic effect of neurodepressant agents.
Topics: Animals; Burns; Central Nervous System Depressants; Chlorpromazine; Diazepam; Dogs; Haloperidol; Hum | 1986 |
The effect of anaesthesia on the haemodynamic and sympathoadrenal responses of the dog in experimental haemorrhagic shock.
Topics: Adrenal Glands; Anesthesia, General; Animals; Blood Pressure; Catecholamines; Consciousness; Dogs; F | 1985 |
Critical bleeding and plasma volumes of the adult germfree rat.
Topics: Anesthesia, General; Anesthesia, Inhalation; Animals; Body Weight; Dye Dilution Technique; Female; G | 1972 |
The effects of oligemic hypotension on myocardial function.
Topics: Animals; Anti-Arrhythmia Agents; Blood Gas Analysis; Coronary Circulation; Disease Models, Animal; D | 1973 |
The effect of hemorrhagic shock on the phospholipid composition of blood plasma of anesthetized dogs.
Topics: Anesthesia, Intravenous; Animals; Brain; Choline; Cranial Sinuses; Dogs; Femoral Artery; Glycerophos | 1974 |
Pancreatic hypoperfusion and the production of a myocardial depressant factor in hemorrhagic shock.
Topics: Acid Phosphatase; Anesthesia, Intravenous; Animals; Blood Flow Velocity; Blood Pressure; Blood Trans | 1974 |
Studies on the pathogenesis of "stress ulcer": electrical potential difference and ionic fluxes across canine gastric mucosa during hemorrhagic shock.
Topics: Action Potentials; Animals; Chlorides; Dogs; Gastric Acidity Determination; Gastric Mucosa; Hydrogen | 1972 |
Regulation of ventilation during hemorrhage and its alterations in response to CO 2 .
Topics: Anesthesia; Animals; Bicarbonates; Blood Chemical Analysis; Carbon Dioxide; Carotid Sinus; Catheteri | 1972 |
Studies on phospholipid metabolism in the lung and alveolar surfactant in experimental traumatic and haemorrhagic shock.
Topics: Anesthesia, General; Animals; Chromatography, Thin Layer; Methods; Pentobarbital; Phosphatidylcholin | 1971 |
Mesenteric blood flow after hemorrhage in anesthetized and unanesthetized dogs.
Topics: Anesthesia; Animals; Blood Pressure; Blood Volume; Cardiac Output; Chloralose; Dogs; Female; Heart; | 1970 |
Hemorrhagic shock and central nervous functions: spinal and spino-bulbo-spinal reflexes.
Topics: Action Potentials; Animals; Blood Pressure; Cats; Electric Stimulation; Electrodes; Evoked Potential | 1970 |
Anesthesia in canine hemorrhagic shock model: relative value of different anesthetic agents and combinations.
Topics: Anesthesia; Anesthetics; Animals; Blood Gas Analysis; Blood Pressure; Blood Volume; Chlorprothixene; | 1968 |
Effect of haemorrhagic shock on the peripheral disposition of catecholamines and (3H)--noradrenaline.
Topics: Animals; Catecholamines; Cats; Female; Heart; Male; Myocardium; Norepinephrine; Organ Size; Pentobar | 1968 |
[Drug effects on shock tolerance in the animal experiment and their clinical significance].
Topics: Acid-Base Equilibrium; Animals; Blood Glucose; Blood Pressure; Chlorprothixene; Hematocrit; Hydrogen | 1968 |
Compensation to exsanguination hypotension in health conscious dogs.
Topics: Animals; Aorta; Blood Pressure; Cardiac Output; Dogs; Heart Rate; Heart Ventricles; Hypotension; Pen | 1963 |