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pentobarbital and Fibrosarcoma

pentobarbital has been researched along with Fibrosarcoma in 6 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Fibrosarcoma: A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"Studies of the effect of pentobarbital anesthesia on the radiation response have been performed using early generation isotransplants of three spontaneous tumors of the C3H mouse: a mammary carcinoma (MCaIV), a fibrosarcoma (FSaII), and a squamous cell carcinoma (SCCVII)."7.67Pentobarbital anesthesia and the response of tumor and normal tissue in the C3Hf/sed mouse to radiation. ( Dosoretz, D; Sedlacek, RS; Silver, G; Suit, HD, 1985)
"Studies of the effect of pentobarbital anesthesia on the radiation response have been performed using early generation isotransplants of three spontaneous tumors of the C3H mouse: a mammary carcinoma (MCaIV), a fibrosarcoma (FSaII), and a squamous cell carcinoma (SCCVII)."3.67Pentobarbital anesthesia and the response of tumor and normal tissue in the C3Hf/sed mouse to radiation. ( Dosoretz, D; Sedlacek, RS; Silver, G; Suit, HD, 1985)
"Pentobarbital anesthesia has been observed to increase markedly the effectiveness of respiration of oxygen at 3 atmospheres of pressure absolute to increase the response of early generation isotransplants of C3H mouse tumors to two-dose irradiation."1.27On the mechanism for enhancement of tumor radiation to hyperbaric oxygen in sodium pentobarbital anesthetized rodents. ( Biaglow, JE; Dosoretz, DE; Durand, RE; Suit, HD, 1984)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Biaglow, JE1
Suit, HD2
Durand, RE1
Dosoretz, DE1
Jayasundar, R1
Hall, LD1
Bleehen, NM2
White, RA1
Workman, P1
Owen, LN1
Steen, RG1
Wilson, DA1
Bowser, C1
Wehrle, JP1
Glickson, JD1
Rajan, SS1
Sedlacek, RS1
Silver, G1
Dosoretz, D1
Gullino, PM1
Grantham, FH1
Courtney, AH1

Other Studies

6 other studies available for pentobarbital and Fibrosarcoma

ArticleYear
On the mechanism for enhancement of tumor radiation to hyperbaric oxygen in sodium pentobarbital anesthetized rodents.
    Advances in experimental medicine and biology, 1984, Volume: 180

    Topics: Animals; Body Temperature; Combined Modality Therapy; Fibrosarcoma; Hyperbaric Oxygenation; Mammary

1984
The effects of anesthesia and physical restraint on intra- and extracellular tumor pH, tumor temperature and bioenergetics in murine RIF-1 tumors.
    Magnetic resonance imaging, 1997, Volume: 15, Issue:7

    Topics: Adjuvants, Anesthesia; Animals; Energy Metabolism; Fibrosarcoma; Hydrogen-Ion Concentration; Magneti

1997
The penetration of misonidazole into spontaneous canine tumours.
    British journal of cancer, 1979, Volume: 40, Issue:2

    Topics: Adenocarcinoma; Anesthesia, Intravenous; Animals; Carcinoma, Squamous Cell; Disease Models, Animal;

1979
31P NMR spectroscopic and near infrared spectrophotometric studies of effects of anesthetics on in vivo RIF-1 tumors. Relationship to tumor radiosensitivity.
    NMR in biomedicine, 1989, Volume: 2, Issue:3

    Topics: Acepromazine; Anesthetics; Animals; Fibrosarcoma; Ketamine; Magnetic Resonance Spectroscopy; Mice; M

1989
Pentobarbital anesthesia and the response of tumor and normal tissue in the C3Hf/sed mouse to radiation.
    Radiation research, 1985, Volume: 104, Issue:1

    Topics: Anesthesia; Animals; Carcinoma, Squamous Cell; Female; Fibrosarcoma; Hyperbaric Oxygenation; Lung Di

1985
Utilization of oxygen by transplanted tumors in vivo.
    Cancer research, 1967, Volume: 27, Issue:6

    Topics: Anemia; Anesthesia, General; Animals; Blood Flow Velocity; Carbon Dioxide; Carcinoma 256, Walker; Ca

1967