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pentobarbital and Fatty Liver with Encephalopathy

pentobarbital has been researched along with Fatty Liver with Encephalopathy in 10 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Research Excerpts

ExcerptRelevanceReference
"Tonic-clinic status epilepticus, which is refractory to phenobarbital, phenytoin, and diazepam, may respond readily to a continuous infusion of pentobarbital."7.66Pentobarbital in refractory status epilepticus. ( Hawkes, D; Ropper, AH; Woods, M; Yohn, P; Young, RS, 1983)
"Tonic-clinic status epilepticus, which is refractory to phenobarbital, phenytoin, and diazepam, may respond readily to a continuous infusion of pentobarbital."3.66Pentobarbital in refractory status epilepticus. ( Hawkes, D; Ropper, AH; Woods, M; Yohn, P; Young, RS, 1983)
"The mitochondrial disturbance in Reye syndrome is well documented but the pathophysiologic sequence linking the antecedent viral illness to the mitochondrial injury remains obscure."2.37Reye syndrome. ( De Vivo, DC, 1985)
"Although most cases of Reye's syndrome that were initially reported were fatal, the overall mortality is now 20 to 30 per cent, with an even lower rate in some series."2.36Reye's syndrome. ( Pascucci, RC; Rockoff, MA, 1983)
"Although the underlying cause of Reye syndrome is not understood, an effective approach to treatment is based on reversing the known metabolic and pathological abnormalities."2.36Treatment of Reye syndrome. ( Trauner, DA, 1980)
" Pentobarbital elimination half-life was not significantly different from control values."1.26High-dose pentobarbital pharmacokinetics in hypothermic brain-injured children. ( Cupit, GC; Rocci, ML; Schaible, DH; Swedlow, DB, 1982)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-199010 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rockoff, MA1
Pascucci, RC1
Young, RS1
Ropper, AH1
Hawkes, D1
Woods, M1
Yohn, P1
Kolata, GB1
Trauner, DA1
Schaible, DH1
Cupit, GC1
Swedlow, DB2
Rocci, ML1
Frewen, TC1
Watcha, M1
Raphaely, RC1
Godinez, RI1
Heiser, MS1
Kettrick, RG1
Bruce, DA1
Clark, JH1
Fitzgerald, JF1
Treadwell, BE1
Turley, CP1
De Vivo, DC1

Reviews

3 reviews available for pentobarbital and Fatty Liver with Encephalopathy

ArticleYear
Reye's syndrome.
    Emergency medicine clinics of North America, 1983, Volume: 1, Issue:1

    Topics: Adolescent; Barbiturates; Catheterization; Child; Child, Preschool; Humans; Intubation, Intratrachea

1983
Treatment of Reye syndrome.
    Annals of neurology, 1980, Volume: 7, Issue:1

    Topics: Brain Diseases; Humans; Intracranial Pressure; Pentobarbital; Reye Syndrome

1980
Reye syndrome.
    Neurologic clinics, 1985, Volume: 3, Issue:1

    Topics: Aflatoxins; Anesthesia, General; Animals; Child; Child, Preschool; Disease Models, Animal; Disease O

1985

Other Studies

7 other studies available for pentobarbital and Fatty Liver with Encephalopathy

ArticleYear
Pentobarbital in refractory status epilepticus.
    Pediatric pharmacology (New York, N.Y.), 1983, Volume: 3, Issue:2

    Topics: Child; Drug Resistance; Electroencephalography; Encephalitis; Female; Humans; Infant; Pentobarbital;

1983
Reye's syndrome: a medical mystery.
    Science (New York, N.Y.), 1980, Mar-28, Volume: 207, Issue:4438

    Topics: Brain Edema; Fatty Liver; Humans; Intracranial Pressure; Mannitol; Mitochondria, Liver; Pentobarbita

1980
High-dose pentobarbital pharmacokinetics in hypothermic brain-injured children.
    The Journal of pediatrics, 1982, Volume: 100, Issue:4

    Topics: Adolescent; Brain Injuries; Child; Child, Preschool; Half-Life; Humans; Hypothermia, Induced; Infant

1982
Outcome in severe Reye syndrome with early pentobarbital coma and hypothermia.
    The Journal of pediatrics, 1982, Volume: 100, Issue:4

    Topics: Brain Edema; Child; Coma; Humans; Hypothermia, Induced; Intracranial Pressure; Outcome and Process A

1982
Reye syndrome in Indiana.
    The Journal of the Indiana State Medical Association, 1981, Volume: 74, Issue:12

    Topics: Adolescent; Adult; Chickenpox; Child; Child, Preschool; Humans; Indiana; Infant; Infant, Newborn; In

1981
Thiopental sodium and pentobarbital sodium in the treatment of Reye's syndrome.
    American journal of hospital pharmacy, 1979, Volume: 36, Issue:11

    Topics: Humans; Pentobarbital; Reye Syndrome; Thiopental

1979
Pentobarbital quantitation using immunoassays in Reye's syndrome patient serum.
    Therapeutic drug monitoring, 1989, Volume: 11, Issue:3

    Topics: Humans; Immunoassay; Pentobarbital; Reye Syndrome

1989