pentobarbital has been researched along with Experimental Radiation Injuries in 20 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Xylazine/ketamine anaesthesia facilitates the development of UVR-induced cataract, whereas pentobarbital anaesthesia does not." | 3.74 | Interaction of anaesthetic drugs and UV-B irradiation in the anterior segment of the rat eye. ( Löfgren, S; Söderberg, PG; Zhang, F, 2007) |
| "Pentobarbital has recently been shown to be a cerebral radioprotectant in the rodent and primate models of single fraction radiation injury." | 1.28 | The cerebral radioprotective effect of alternative barbiturates to pentobarbital. ( DeLaney, T; Oldfield, EH; Olson, JJ; Orr, K; Shelley, C, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (75.00) | 18.7374 |
| 1990's | 4 (20.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HSIEH, MC | 1 |
| SUNG, CY | 1 |
| NIELSEN, NO | 1 |
| HIETBRINK, BE | 1 |
| KESHMIRI, M | 1 |
| DUBOIS, KP | 1 |
| MEREDITH, OM | 1 |
| BOWERS, EG | 1 |
| HEINTZELMAN, JT | 1 |
| FRIDRICH, R | 1 |
| Zhang, F | 1 |
| Löfgren, S | 1 |
| Söderberg, PG | 1 |
| Asegawa, AT | 1 |
| Landahl, HD | 2 |
| Moos, WS | 1 |
| LeVan, H | 1 |
| Mason, HC | 1 |
| Alter, WA | 1 |
| Catravas, GN | 1 |
| Hawkins, RN | 1 |
| Lake, CR | 1 |
| Kondziolka, D | 1 |
| Somaza, S | 1 |
| Flickinger, JC | 1 |
| Claassen, D | 1 |
| Lunsford, LD | 1 |
| Hendry, JH | 1 |
| Criborn, CO | 1 |
| Rönnbäck, C | 1 |
| Olson, JJ | 2 |
| Shelley, C | 1 |
| Orr, K | 2 |
| DeLaney, T | 1 |
| Oldfield, EH | 2 |
| Friedman, R | 1 |
| Kinsella, T | 1 |
| Moquin, R | 1 |
| DeLuca, AM | 1 |
| Skolnick, A | 1 |
| Schultz, RD | 1 |
| Steers, CW | 1 |
| Norman, D | 1 |
| Whitcomb, WH | 1 |
| Young, RJ | 1 |
| Melville, GS | 1 |
| Pitcock, JA | 1 |
| Anderson, DR | 1 |
| Hasegawa, AT | 1 |
| Devik, F | 1 |
| Merriam, GR | 1 |
| Focht, EF | 1 |
| Parsons, RW | 1 |
| Schwartz, HS | 1 |
20 other studies available for pentobarbital and Experimental Radiation Injuries
| Article | Year |
|---|---|
[CHANGES IN THE EFFECT OF SODIUM PENTOBARBITAL IN IRRADIATED ANIMALS].
Topics: Animals; Electroencephalography; Lagomorpha; Metabolism; Mice; Pentobarbital; Pharmacology; Rabbits; | 1963 |
EFFECT OF WHOLE-BODY X-IRRADIATION ON GLUCOSE TOLERANCE IN THE DOG.
Topics: Carbohydrate Metabolism; Dogs; Glucose; Glucose Tolerance Test; Pentobarbital; Radiation Effects; Ra | 1964 |
THE EFFECTS OF IONIZING RADIATION ON THE BIOCHEMISTRY OF MAMMALIAN TISSUES. II. INFLUENCE OF X-IRRADIATION ON THE DEVELOPMENT OF A THIOPHOSPHATE-OXIDIZING ENZYME SYSTEM IN THE LIVERS OF YOUNG MALE RATS. QUART PROGR REP 48.
Topics: Clinical Enzyme Tests; Liver; Oxidoreductases; Pentobarbital; Pharmacology; Phosphates; Radiation In | 1963 |
THE COMPARATIVE PROTECTIVE ACTIONS OF AET (B-AMINOETHYLISOTHIURONIUM) OR SEROTONIN IN EXPERIMENTAL BETA RADIATION INJURY.
Topics: Animals; beta-Aminoethyl Isothiourea; Body Weight; Body Weights and Measures; Injections, Intraperit | 1964 |
[THE EFFECTS OF COMBINED STRESS ON THE IRRADIATED ORGANISM].
Topics: Cold Temperature; Mice; Morphine; Pentobarbital; Radiation; Radiation Effects; Radiation Injuries; R | 1964 |
Interaction of anaesthetic drugs and UV-B irradiation in the anterior segment of the rat eye.
Topics: Analgesics; Anesthetics, Dissociative; Animals; Cataract; Cornea; Drug Interactions; Female; Ketamin | 2007 |
Studies on spleen oxygen tension and radioprotection in mice with hypoxia, serotonin, and p-aminopropiophenone.
Topics: Animals; Antidotes; Hypoxia; Male; Mice; Nitrites; Oximetry; Oxygen; Pentobarbital; Propiophenones; | 1967 |
Radioprotective effects of dimethyl sulfoxide vapor on mice.
Topics: Animals; Dimethyl Sulfoxide; Male; Mice; Pentobarbital; Radiation Injuries, Experimental; Radiation- | 1967 |
Effect of ionizing radiation on physiological function in the anesthetized rat.
Topics: Anesthesia; Animals; beta-Endorphin; Blood Pressure; Electrons; Endorphins; Epinephrine; Heart Rate; | 1984 |
Cerebral radioprotective effects of high-dose pentobarbital evaluated in an animal radiosurgery model.
Topics: Animals; Brain; Necrosis; Pentobarbital; Radiation Injuries, Experimental; Radiation-Protective Agen | 1994 |
Radionecrosis of normal tissue: studies on mouse tails.
Topics: Anesthetics; Animals; Dose-Response Relationship, Radiation; Female; Mice; Necrosis; Oxygen; Pentoba | 1978 |
Pharmacologic effects of radiation protective compounds related to their protective effect in mice.
Topics: Amphetamine; Animals; Body Temperature; Cysteamine; Male; Mercaptoethanol; Mice; Mice, Inbred CBA; M | 1979 |
The cerebral radioprotective effect of alternative barbiturates to pentobarbital.
Topics: Animals; Barbiturates; Brain Neoplasms; Male; Methohexital; Pentobarbital; Phenobarbital; Radiation | 1992 |
Reduction in radiation-induced brain injury by use of pentobarbital or lidocaine protection.
Topics: Animals; Brain; Brain Diseases; Dose-Response Relationship, Radiation; Lidocaine; Monitoring, Physio | 1990 |
Primate study suggests pentobarbital may help protect the brain during radiation therapy.
Topics: Animals; Brain Diseases; Macaca mulatta; Male; Pentobarbital; Radiation Injuries, Experimental; Radi | 1990 |
Radiation protection by an auxin analogue, beta-2,4,5-trichlorophenoxyethanol, in C57BL-6J mice exposed to cobalt-60 gamma radiation.
Topics: Animals; Cobalt Isotopes; Herbicides; Intestines; Mice; Oxygen Consumption; Pentobarbital; Pseudomon | 1965 |
Chemical protection of irradiated monkeys in combination with autologous and homologous marrow transfusion.
Topics: Alanine Transaminase; Animals; beta-Aminoethyl Isothiourea; Bone Marrow Transplantation; Cysteine; E | 1966 |
Dose reduction factor for radiation lethality in mice as a function of the dose of mercaptoethylamine.
Topics: Animals; Body Temperature; Injections, Intraperitoneal; Injections, Intravenous; Mercaptoethylamines | 1970 |
Intestinal cell kinetics in irradiated mice. A quantitative investigation of the acute reaction to whole body roentgen irradiation.
Topics: Anesthesia; Animals; Cell Count; Cell Movement; Duodenum; Epithelium; Female; Ileum; Intestinal Muco | 1971 |
Influence of anesthesia on radiation effect. Experimental cataracts.
Topics: Anesthesia; Animals; Cataract; Female; Pentobarbital; Radiation Injuries, Experimental; Radiation-Pr | 1968 |