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pentobarbital and Epilepsies, Partial

pentobarbital has been researched along with Epilepsies, Partial in 5 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Epilepsies, Partial: Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317)

Research Excerpts

ExcerptRelevanceReference
"To determine whether epidural pentobarbital (PB) delivery can prevent and/or terminate neocortical seizures induced by locally administered acetylcholine (Ach) in freely moving rats."7.73Epidural pentobarbital delivery can prevent locally induced neocortical seizures in rats: the prospect of transmeningeal pharmacotherapy for intractable focal epilepsy. ( Baptiste, SL; Devinsky, O; Doyle, WK; John, JE; Kuzniecky, RI; Ludvig, N; von Gizycki, H, 2006)
"To determine whether epidural pentobarbital (PB) delivery can prevent and/or terminate neocortical seizures induced by locally administered acetylcholine (Ach) in freely moving rats."3.73Epidural pentobarbital delivery can prevent locally induced neocortical seizures in rats: the prospect of transmeningeal pharmacotherapy for intractable focal epilepsy. ( Baptiste, SL; Devinsky, O; Doyle, WK; John, JE; Kuzniecky, RI; Ludvig, N; von Gizycki, H, 2006)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ludvig, N1
Kuzniecky, RI1
Baptiste, SL1
John, JE1
von Gizycki, H1
Doyle, WK1
Devinsky, O1
Jennum, P1
Dam, M1
Fuglsang-Frederiksen, A1
Brückner, C1
Heinemann, U1
Hablitz, JJ1
Wray, DV1
Crowell, RM1

Other Studies

5 other studies available for pentobarbital and Epilepsies, Partial

ArticleYear
Epidural pentobarbital delivery can prevent locally induced neocortical seizures in rats: the prospect of transmeningeal pharmacotherapy for intractable focal epilepsy.
    Epilepsia, 2006, Volume: 47, Issue:11

    Topics: Acetylcholine; Animals; Anticonvulsants; Cerebrospinal Fluid; Disease Models, Animal; Drug Administr

2006
Effect of barbiturate on epileptiform activity: comparison between intravenous and oral administration. Sphenoidal, zygomatic and temporal recordings.
    Acta neurologica Scandinavica, 1993, Volume: 88, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Brain; Electrodes; Electroencephalography; Epilepsies, Part

1993
Effects of standard anticonvulsant drugs on different patterns of epileptiform discharges induced by 4-aminopyridine in combined entorhinal cortex-hippocampal slices.
    Brain research, 2000, Mar-17, Volume: 859, Issue:1

    Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbamazepine; Entorhinal Cortex; Epilepsies, Partial; Fe

2000
Focal penicillin epilepsy in an isolated cerebral hemisphere.
    Experimental neurology, 1978, Volume: 62, Issue:2

    Topics: Administration, Topical; Animals; Cats; Cerebral Cortex; Electroencephalography; Epilepsies, Partial

1978
Projected effects in focal epilepsy.
    Neurology, 1970, Volume: 20, Issue:4

    Topics: Anesthesia, Local; Animals; Cats; Cerebral Cortex; Electric Stimulation; Epilepsies, Partial; Neuron

1970