pentobarbital has been researched along with Endotoxemia in 5 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pentobarbital is an anesthetic used mainly in animal studies." | 5.34 | The reduction of tumor necrosis factor-alpha release and tissue damage by pentobarbital in the experimental endotoxemia model. ( Chen, HI; Harn, HJ; Hsu, BG; Lee, RP; Li, CH; Liao, KW; Lin, SZ; Tsai, NM; Yang, FL, 2007) |
| "Pentobarbital is an anesthetic used mainly in animal studies." | 1.34 | The reduction of tumor necrosis factor-alpha release and tissue damage by pentobarbital in the experimental endotoxemia model. ( Chen, HI; Harn, HJ; Hsu, BG; Lee, RP; Li, CH; Liao, KW; Lin, SZ; Tsai, NM; Yang, FL, 2007) |
| "Urethane/chloralose-treated mice demonstrated hypoglycaemia and enhanced serum levels of ALT and creatinine in response to LPS, but failed to show LPS-induced increases in serum lipase and lung MPO activity." | 1.33 | Comparison of urethane/chloralose and pentobarbitone anaesthesia for examining effects of bacterial lipopolysaccharide in mice. ( Furman, BL; Kazerani, HR, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kazerani, HR | 1 |
| Furman, BL | 1 |
| Lehmann, Ch | 1 |
| Feyerherd, F | 1 |
| Feyerherd, T | 1 |
| Fogliata, M | 1 |
| Gründling, M | 1 |
| Usichenko, TI | 1 |
| Meissner, K | 1 |
| Wendt, M | 1 |
| Pavlovic, D | 1 |
| Yang, FL | 1 |
| Li, CH | 1 |
| Hsu, BG | 1 |
| Tsai, NM | 1 |
| Lin, SZ | 1 |
| Harn, HJ | 1 |
| Chen, HI | 1 |
| Liao, KW | 1 |
| Lee, RP | 1 |
| Hoque, AM | 1 |
| Marczin, N | 1 |
| Catravas, JD | 1 |
| Fuchs, LC | 1 |
| Cheng, X | 1 |
| Pang, CC | 1 |
5 other studies available for pentobarbital and Endotoxemia
| Article | Year |
|---|---|
Comparison of urethane/chloralose and pentobarbitone anaesthesia for examining effects of bacterial lipopolysaccharide in mice.
Topics: Alanine Transaminase; Anesthetics, Combined; Anesthetics, General; Animals; Blood Glucose; Chloralos | 2006 |
Ketamine does not affect intestinal microcirculation in pentobarbital-anaesthetized rats during experimental endotoxaemia.
Topics: Analgesics; Anesthesia, Intravenous; Anesthetics; Animals; Blood Pressure; Cytokines; Endotoxemia; E | 2007 |
The reduction of tumor necrosis factor-alpha release and tissue damage by pentobarbital in the experimental endotoxemia model.
Topics: Anesthetics; Animals; Apoptosis; Cell Line; Endotoxemia; Humans; Hypoxia; Lipopolysaccharides; Mice; | 2007 |
Anesthesia with sodium pentobarbital enhances lipopolysaccharide-induced cardiovascular dysfunction in rats.
Topics: Adjuvants, Anesthesia; Anesthesia; Animals; Antidotes; Arterioles; Blood Pressure; Cardiovascular Sy | 1996 |
Pressor and vasoconstrictor effects of methylene blue in endotoxaemic rats.
Topics: Animals; Blood Pressure; Cardiac Output; Endotoxemia; Endotoxins; Hypnotics and Sedatives; Lipopolys | 1998 |