Page last updated: 2024-11-02

pentobarbital and Emesis, Postoperative

pentobarbital has been researched along with Emesis, Postoperative in 1 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Research Excerpts

ExcerptRelevanceReference
"Propofol may produce its antiemetic effect by depleting the area postrema of serotonin as well as by a direct gamma-aminobutyric acid-mediated inhibition."1.31The effects of propofol in the area postrema of rats. ( Cechetto, DF; Diab, T; Gelb, AW; Gibson, CJ, 2001)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cechetto, DF1
Diab, T1
Gibson, CJ1
Gelb, AW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Optimizing Anesthesia Antiemetic Measures Versus Combination With Dexamethasone or Ondansetron in the Prevention of Postoperative Nausea and Vomiting.[NCT00825071]Phase 4180 participants (Actual)Interventional2007-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for pentobarbital and Emesis, Postoperative

ArticleYear
The effects of propofol in the area postrema of rats.
    Anesthesia and analgesia, 2001, Volume: 92, Issue:4

    Topics: Anesthetics, Intravenous; Animals; Electric Stimulation; Electrophysiology; Fourth Ventricle; GABA-A

2001