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pentobarbital and Coronary Disease

pentobarbital has been researched along with Coronary Disease in 23 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"The effect of halothane on arrhythmias induced by ischaemia was investigated in rats, isolated perfused rat hearts, and pigs."7.67Effects of halothane on arrhythmias induced by myocardial ischaemia. ( MacLeod, BA; McGroarty, R; Morton, RH; Walker, MJ, 1989)
"The effect of halothane on arrhythmias induced by ischaemia was investigated in rats, isolated perfused rat hearts, and pigs."3.67Effects of halothane on arrhythmias induced by myocardial ischaemia. ( MacLeod, BA; McGroarty, R; Morton, RH; Walker, MJ, 1989)
"Thus, reperfusion arrhythmias after a 15 minute occlusion of the left anterior descending coronary artery were compared in 24 open chest dogs (17 anesthetized with pentobarbital and 7 with chloralose plus urethane) and 25 conscious, unsedated, trained dogs."1.27Disparity of reperfusion arrhythmias after reversible myocardial ischemia in open chest and conscious dogs. ( Bolli, R; Myers, ML; Roberts, R; Zhu, WX, 1986)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199023 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Altura, BM1
Altura, BT1
Platou, ES1
Steinnes, K1
Refsum, H1
Kositskiĭ, GI1
Mikhailova, SD1
Putygin, SV1
Komai, H1
Berkoff, HA1
Rusy, BF1
Evans, DB1
Parham, CS1
Laffan, RJ1
Palacios, I1
Newell, JB1
Powell, WJ1
Schwartz, JS2
Bache, RJ2
Dai, S1
Manning, AS1
Crome, R1
Klein, N1
Hearse, DJ1
Maguire, ME1
MacLeod, BA1
McGroarty, R1
Morton, RH1
Walker, MJ1
Preuss, KC1
Gross, GJ1
Brooks, HL1
Warltier, DC1
Kaufman, WR1
Jugdutt, BI1
Tatekawa, S1
Traber, KB1
Hantler, CB1
Tait, AR1
Gallagher, KP1
Knight, PR1
Yahagi, N1
Furuya, H1
Homans, DC1
Sublett, E1
Elsperger, KJ1
Bolli, R1
Myers, ML1
Zhu, WX1
Roberts, R1
Puddu, PE1
Jouve, R1
Guillen, JC1
Langlet, F1
Noirclerc, M1
Reale, A1
Torresani, J1
Spear, JF1
Moore, EN1
Gerstenblith, G1
Lochner, W1
Raff, WK1
Kosche, F1
Peterson, KL1
Skloven, D1
Ludbrook, P1
Uther, JB1
Ross, J1
David, MS1
Charrette, EJ1
Lynn, RB1
Kato, K1
Fukuda, H1
Koyama, S1
Sommers, HM1
Wessel, HU1
Jennings, RB1

Reviews

1 review available for pentobarbital and Coronary Disease

ArticleYear
Microcirculatory actions and uses of naturally-occurring (magnesium) and novel synthetic calcium channel blockers.
    Microcirculation, endothelium, and lymphatics, 1984, Volume: 1, Issue:2

    Topics: Anesthesia; Animals; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Cell Membrane Pe

1984

Other Studies

22 other studies available for pentobarbital and Coronary Disease

ArticleYear
A method for simultaneous epicardial monophasic action potential recordings from the dog heart in situ.
    Acta pharmacologica et toxicologica, 1984, Volume: 54, Issue:2

    Topics: Action Potentials; Animals; Coronary Disease; Coronary Vessels; Dogs; Electrophysiology; Female; Hea

1984
[Effect of anesthesia on the development of ventricular fibrillation in experimental myocardial ischemia].
    Kardiologiia, 1981, Volume: 21, Issue:1

    Topics: Anesthesia, General; Animals; Cats; Coronary Disease; Female; Male; Pentobarbital; Ventricular Fibri

1981
Protection of ischemic rat heart by cardioplegic doses of pentobarbital.
    The Journal of surgical research, 1981, Volume: 30, Issue:1

    Topics: Animals; Blood Pressure; Coronary Disease; Dose-Response Relationship, Drug; Female; Heart Arrest, I

1981
Non-specific myocardial depression by beta-adrenergic receptor blockers in normal and compromised myocardium.
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 240, Issue:2

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Cats; Coronary Disease; In Vitro Techniques; Myoca

1979
Effects of acute global ischemia on diastolic relaxation in canine hearts.
    The American journal of physiology, 1978, Volume: 235, Issue:6

    Topics: Animals; Blood Pressure; Coronary Disease; Diastole; Dogs; Myocardial Contraction; Pentobarbital; Ti

1978
Effect of anesthesia on reactivity of large coronary arteries in the dog.
    Journal of cardiovascular pharmacology, 1987, Volume: 9, Issue:1

    Topics: Anesthesia; Animals; Blood Pressure; Chloralose; Coronary Disease; Coronary Vessels; Dogs; Droperido

1987
Anaesthetic-related occurrence of early ventricular arrhythmias during acute myocardial ischaemia in rats.
    Archives internationales de physiologie et de biochimie, 1989, Volume: 97, Issue:5

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Blood Pressure; Chloralose; Coronary Disease; Coronary Ve

1989
Dissociation between reperfusion induced arrhythmias and increases in ventricular alpha 1 receptor density in the anaesthetised rat.
    Cardiovascular research, 1989, Volume: 23, Issue:10

    Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Heart Ventricles; Male; Myocardial Reperfusion Inju

1989
Effects of halothane on arrhythmias induced by myocardial ischaemia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1989, Volume: 36, Issue:3 Pt 1

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Catheterization, Swan-Ganz; Coronary

1989
Time course of recovery of "stunned" myocardium following variable periods of ischemia in conscious and anesthetized dogs.
    American heart journal, 1987, Volume: 114, Issue:4 Pt 1

    Topics: Anesthesia, Intravenous; Animals; Consciousness; Coronary Circulation; Coronary Disease; Dogs; Femal

1987
Left ventricular catecholamines during acute myocardial infarction in the dog.
    Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:2

    Topics: Anesthesia; Animals; Catecholamines; Coronary Disease; Dogs; Dopamine; Epinephrine; Myocardial Infar

1987
Effects of isoflurane on myocardial blood flow, function, and oxygen consumption in the presence of critical coronary stenosis in dogs.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:11

    Topics: Animals; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Female; Heart; Isoflurane;

1987
The effects of halothane and pentobarbital on the threshold of transpulmonary passage of venous air emboli in dogs.
    Anesthesiology, 1987, Volume: 67, Issue:6

    Topics: Anesthesia, General; Animals; Coronary Disease; Dogs; Echocardiography; Embolism, Air; Halothane; Pe

1987
Mechanisms of remote myocardial dysfunction during coronary artery occlusion in the presence of multivessel disease.
    Circulation, 1986, Volume: 74, Issue:3

    Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Dogs; Hemodynamics; Myocardial Cont

1986
Disparity of reperfusion arrhythmias after reversible myocardial ischemia in open chest and conscious dogs.
    Journal of the American College of Cardiology, 1986, Volume: 7, Issue:5

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Chloralose; Coronary Circulation; Coronary Disease; Dogs;

1986
[An anesthetic technic in dogs for studying the arrhythmogenic effects of acute coronary occlusion].
    Journal de physiologie, 1985, Volume: 80, Issue:1

    Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Atropine; Coronary Disease; Coronary Vessels; Di

1985
Effect of lidocaine on the ventricular fibrillation threshold in the dog during acute ischemia and premature ventricular contractions.
    Circulation, 1972, Volume: 46, Issue:1

    Topics: Anesthesia, General; Animals; Cardiac Complexes, Premature; Coronary Disease; Dogs; Female; Infusion

1972
[Coronary flow resistance in heart failure and circulatory insufficiency].
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1972, Volume: 38

    Topics: Animals; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Heart Failure; Pentobarbita

1972
Comparison of isovolumic and ejection phase indices of myocardial performance in man.
    Circulation, 1974, Volume: 49, Issue:6

    Topics: Adult; Angiocardiography; Arteriosclerosis; Blood Pressure; Cardiac Catheterization; Cardiac Output;

1974
Experimental coronary artery thrombosis for production of cardiogenic shock.
    Canadian journal of surgery. Journal canadien de chirurgie, 1970, Volume: 13, Issue:2

    Topics: Anesthesia; Animals; Arteries; Blood Pressure; Bretylium Compounds; Cardiac Catheterization; Cardiac

1970
Depression of the S-T segment in epicardial electrocardiogram associated with experimental major coronary artery constriction.
    Journal of electrocardiology, 1968, Volume: 1, Issue:2

    Topics: Angina Pectoris; Animals; Coronary Disease; Coronary Vessels; Dogs; Electrocardiography; Electrodes;

1968
Myocardial temperature changes in acute experimental infarction.
    Laboratory investigation; a journal of technical methods and pathology, 1966, Volume: 15, Issue:12

    Topics: Animals; Body Temperature; Coronary Disease; Cyanosis; Dogs; Electrocardiography; Female; Heart; Mal

1966