Page last updated: 2024-11-02

pentobarbital and Cocaine Abuse

pentobarbital has been researched along with Cocaine Abuse in 3 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Research Excerpts

ExcerptRelevanceReference
"Pentobarbital (42mg/kg) was administered intraperitoneally (i."1.35Cocaine withdrawal enhances pentobarbital-induced sleep in rats: evidence of GABAergic modulation. ( Hong, JT; Kim, YB; Ma, H; Ma, Y; Nam, SY; Oh, KW, 2008)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Scroggin, TL1
McMillin, GA1
Ma, Y1
Ma, H1
Hong, JT1
Kim, YB1
Nam, SY1
Oh, KW1
Singha, AK1
McCance-Katz, EF1
Petrakis, I1
Kosten, TR1
Oliveto, A1

Trials

1 trial available for pentobarbital and Cocaine Abuse

ArticleYear
Sex differences in self-reported and physiological response to oral cocaine and placebo in humans.
    The American journal of drug and alcohol abuse, 2000, Volume: 26, Issue:4

    Topics: Administration, Oral; Adult; Antipsychotic Agents; Blood Pressure; Chlorpromazine; Cocaine; Cocaine-

2000

Other Studies

2 other studies available for pentobarbital and Cocaine Abuse

ArticleYear
Quantitation of Cocaine and Metabolites, Phencyclidine, Butalbital and Phenobarbital in Meconium by Liquid Chromatography-Tandem Mass Spectrometry.
    Journal of analytical toxicology, 2018, Apr-01, Volume: 42, Issue:3

    Topics: Barbiturates; Biotransformation; Chromatography, Liquid; Cocaine; Cocaine-Related Disorders; Female;

2018
Cocaine withdrawal enhances pentobarbital-induced sleep in rats: evidence of GABAergic modulation.
    Behavioural brain research, 2008, Dec-01, Volume: 194, Issue:1

    Topics: Anesthetics, Local; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Drug Synergism; G

2008