pentobarbital has been researched along with Closed Head Injuries in 3 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The diagnosis of brain death and the implications of pentobarbital intoxication during a brain death examination are discussed." | 1.35 | Head injuries, pentobarbital, and the determination of death. ( McCutcheon, JR; Molina, DK; Rulon, JJ, 2009) |
| "Pentobarbital was unable to significantly modulate mitochondrial function in traumatized rats, whereas it exerted this effect in all control animals." | 1.33 | Pentobarbital fails to reduce cerebral oxygen consumption early after non-hemorrhagic closed head injury in rats. ( Borgers, M; De Visscher, G; Flameng, W; Jorens, P; Reneman, RS; Rooker, S; Van Rossem, K; Verlooy, J, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Molina, DK | 1 |
| McCutcheon, JR | 1 |
| Rulon, JJ | 1 |
| De Visscher, G | 1 |
| Rooker, S | 1 |
| Jorens, P | 1 |
| Verlooy, J | 1 |
| Borgers, M | 1 |
| Reneman, RS | 1 |
| Van Rossem, K | 1 |
| Flameng, W | 1 |
| Segal, J | 1 |
3 other studies available for pentobarbital and Closed Head Injuries
| Article | Year |
|---|---|
Head injuries, pentobarbital, and the determination of death.
Topics: Accidents, Traffic; Adolescent; Adult; Brain Death; Coma; Female; Forensic Pathology; Head Injuries, | 2009 |
Pentobarbital fails to reduce cerebral oxygen consumption early after non-hemorrhagic closed head injury in rats.
Topics: Animals; Brain Injuries; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Down- | 2005 |
Prolonged barbiturate therapy in a patient with closed head injury and jugular venous thrombosis.
Topics: Adult; Combined Modality Therapy; Critical Care; Dose-Response Relationship, Drug; Drug Administrati | 1993 |