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pentobarbital and Cardiovascular Stroke

pentobarbital has been researched along with Cardiovascular Stroke in 29 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Research Excerpts

ExcerptRelevanceReference
"We investigated the incidence of ventricular arrhythmias, extent of myocardial infarction and alteration in haemodynamic parameters during 30 minutes of coronary arterial occlusion in rabbits anaesthetized with halothane, alpha chloralose and pentobarbitone."7.68Arrhythmias, haemodynamic changes and extent of myocardial damage during coronary ligation in rabbits anaesthetized with halothane, alpha chloralose or pentobarbitone. ( Chakrabarty, S; Sheridan, DJ; Thomas, P, 1991)
"Using a high-frequency linear transducer (15L8), we studied 1) the feasibility of performing echocardiography in nonanesthetized mice compared with mice given pentobarbital sodium (Pento) or a mixture of ketamine and xylazine and 2) the feasibility of echocardiographic evaluation of left ventricular (LV) hypertrophy, dilatation, and function in mice with two-kidney, one-clip hypertension or myocardial infarction (MI)."3.70Echocardiographic assessment of cardiac function in conscious and anesthetized mice. ( Carretero, OA; Kim, HE; Kurihara, N; Liu, YH; Rhaleb, NE; Yang, XP, 1999)
" each) to reduce myocardial O2 consumption, and (c) when xylazine was added to pentobarbital anesthesia."3.69Glibenclamide, a blocker of ATP-sensitive potassium channels, abolishes infarct size limitation by preconditioning in rabbits anesthetized with xylazine/pentobarbital but not with pentobarbital alone. ( Goto, M; Iimura, O; Miki, T; Miura, T; Sakamoto, J; Shimamoto, K, 1995)
"We investigated the incidence of ventricular arrhythmias, extent of myocardial infarction and alteration in haemodynamic parameters during 30 minutes of coronary arterial occlusion in rabbits anaesthetized with halothane, alpha chloralose and pentobarbitone."3.68Arrhythmias, haemodynamic changes and extent of myocardial damage during coronary ligation in rabbits anaesthetized with halothane, alpha chloralose or pentobarbitone. ( Chakrabarty, S; Sheridan, DJ; Thomas, P, 1991)
"Cromakalim pretreatment (both when given throughout the experiment and when not present in the reperfusion buffer) resulted in significant improvements in the reperfusion function."1.28The protective effects of cromakalim and pinacidil on reperfusion function and infarct size in isolated perfused rat hearts and anesthetized dogs. ( Dzwonczyk, S; Grover, GJ; Parham, CS; Sleph, PG, 1990)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199016 (55.17)18.7374
1990's9 (31.03)18.2507
2000's2 (6.90)29.6817
2010's2 (6.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Behmenburg, F1
van Caster, P1
Bunte, S1
Brandenburger, T1
Heinen, A1
Hollmann, MW1
Huhn, R1
Larsen, JR1
Aagaard, S1
Lie, RH1
Sloth, E1
Hasenkam, JM1
Karlsson, LO1
Zhou, AX1
Larsson, E1
Aström-Olsson, K1
Månsson, C1
Akyürek, LM1
Grip, L1
Haelewyn, B1
Zhu, L1
Hanouz, JL1
Persehaye, E1
Roussel, S1
Ducouret, P1
Gérard, JL1
Dlabal, PW1
Stutts, BS1
Floyd, J1
Oliveros, RA1
Beckmann, CH1
Ytrehus, K1
Liu, Y1
Tsuchida, A1
Miura, T2
Liu, GS1
Yang, XM1
Herbert, D1
Cohen, MV1
Downey, JM1
Goto, M1
Miki, T1
Sakamoto, J1
Shimamoto, K1
Iimura, O1
Haessler, R1
Kuzume, K1
Chien, GL1
Wolff, RA1
Davis, RF1
Van Winkle, DM1
Iliodromitis, EK1
Kremastinos, DT1
Katritsis, DG1
Papadopoulos, CC1
Hearse, DJ1
Schwartz, LM1
Jennings, RB2
Reimer, KA1
Yang, XP1
Liu, YH1
Rhaleb, NE1
Kurihara, N1
Kim, HE1
Carretero, OA1
Roberts, R1
Sobel, BE1
Franciosa, JA1
Notargiacomo, AV1
Cohn, JN1
Heckel, RC1
Chakrabarty, S1
Thomas, P1
Sheridan, DJ1
Grover, GJ1
Dzwonczyk, S1
Parham, CS1
Sleph, PG1
Conway, DR1
Kim, D1
Djuricin, G1
VanDenburgh, A1
Jacobs, HK1
Rosel, TJ1
Prinz, RA1
Hunt, GB1
Ross, DL1
Kaufman, WR1
Jugdutt, BI2
Homans, DC1
Sublett, E1
Elsperger, KJ1
Schwartz, JS1
Bache, RJ1
Mergner, GW1
Mergner, WJ1
Stoiko, M1
Grayson, J1
Lapin, BA1
Siegel, JH1
Feola, M1
Haiderer, O1
Kennedy, JH1
Louhimo, I1
David, MS1
Charrette, EJ1
Lynn, RB1
Kumar, S1
Srivastava, S1
Hood, WB1
McCarthy, B1
Lown, B1
Sommers, HM1
Wessel, HU1

Reviews

1 review available for pentobarbital and Cardiovascular Stroke

ArticleYear
The myocardial contractile state and its role in the response to anesthesia and surgery.
    Anesthesiology, 1969, Volume: 30, Issue:5

    Topics: Anesthesia; Anesthetics; Animals; Biomechanical Phenomena; Blood Pressure; Blood Volume; Calcium; Di

1969

Other Studies

28 other studies available for pentobarbital and Cardiovascular Stroke

ArticleYear
Impact of Anesthetic Regimen on Remote Ischemic Preconditioning in the Rat Heart In Vivo.
    Anesthesia and analgesia, 2018, Volume: 126, Issue:4

    Topics: Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Disease Models, Anim

2018
Sevoflurane improves myocardial ischaemic tolerance in a closed-chest porcine model.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:10

    Topics: Adjuvants, Anesthesia; Anesthetics, Inhalation; Animals; Disease Models, Animal; Female; Methyl Ethe

2008
Cyclosporine does not reduce myocardial infarct size in a porcine ischemia-reperfusion model.
    Journal of cardiovascular pharmacology and therapeutics, 2010, Volume: 15, Issue:2

    Topics: Anesthetics; Animals; Apoptosis Inducing Factor; Caspase 3; Cyclosporine; Disease Models, Animal; Dr

2010
Cardioprotective effects of desflurane: effect of timing and duration of administration in rat myocardium.
    British journal of anaesthesia, 2004, Volume: 92, Issue:4

    Topics: Adjuvants, Anesthesia; Anesthetics, Inhalation; Animals; Blood Pressure; Cardiotonic Agents; Desflur

2004
Behavior of serum myoglobin during cardiac catheterization: concise communication.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1981, Volume: 22, Issue:9

    Topics: Adult; Cardiac Catheterization; Coronary Angiography; Heart Injuries; Humans; Myocardial Infarction;

1981
Rat and rabbit heart infarction: effects of anesthesia, perfusate, risk zone, and method of infarct sizing.
    The American journal of physiology, 1994, Volume: 267, Issue:6 Pt 2

    Topics: Anesthesia; Animals; Buffers; Disease Models, Animal; Female; Histocytochemistry; Male; Myocardial I

1994
Glibenclamide, a blocker of ATP-sensitive potassium channels, abolishes infarct size limitation by preconditioning in rabbits anesthetized with xylazine/pentobarbital but not with pentobarbital alone.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:4

    Topics: Adenosine Triphosphate; Anesthesia; Animals; Blood Glucose; Blood Pressure; Glyburide; Heart Rate; M

1995
Anaesthetics alter the magnitude of infarct limitation by ischaemic preconditioning.
    Cardiovascular research, 1994, Volume: 28, Issue:10

    Topics: Anesthetics; Animals; Blood Glucose; Constriction; Coronary Vessels; Heart; Isoflurane; Ketamine; My

1994
Multiple cycles of preconditioning cause loss of protection in open-chest rabbits.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:3

    Topics: Anesthesia, Intravenous; Animals; Blood Pressure; Heart Rate; Ischemic Preconditioning, Myocardial;

1997
Premedication with the opioid analgesic butorphanol raises the threshold for ischemic preconditioning in dogs.
    Basic research in cardiology, 1997, Volume: 92, Issue:2

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Butorphanol; Cardiotonic Agents; Coronary Circula

1997
Echocardiographic assessment of cardiac function in conscious and anesthetized mice.
    The American journal of physiology, 1999, Volume: 277, Issue:5

    Topics: Adjuvants, Anesthesia; Anesthesia, General; Anesthetics, Dissociative; Animals; Drug Combinations; E

1999
Effect of selected drugs and myocardial infarction on the disappearance of creatine kinase from the circulation in conscious dogs.
    Cardiovascular research, 1977, Volume: 11, Issue:2

    Topics: Animals; Creatine Kinase; Diazepam; Dogs; Kinetics; Morphine; Myocardial Infarction; Pentobarbital

1977
Importance of state of consciousness in determining hemodynamic responses to acute coronary occlusion in the dog.
    Circulatory shock, 1977, Volume: 4, Issue:3

    Topics: Anesthesia, General; Animals; Blood Pressure; Cardiac Output; Consciousness; Disease Models, Animal;

1977
Arrhythmias, haemodynamic changes and extent of myocardial damage during coronary ligation in rabbits anaesthetized with halothane, alpha chloralose or pentobarbitone.
    International journal of cardiology, 1991, Volume: 31, Issue:1

    Topics: Analysis of Variance; Anesthesia, General; Animals; Arrhythmias, Cardiac; Blood Pressure; Chloralose

1991
The protective effects of cromakalim and pinacidil on reperfusion function and infarct size in isolated perfused rat hearts and anesthetized dogs.
    Cardiovascular drugs and therapy, 1990, Volume: 4, Issue:2

    Topics: Animals; Benzopyrans; Blood Pressure; Cromakalim; Dogs; Female; Guanidines; In Vitro Techniques; L-L

1990
The effect of parathyroid hormone on the acutely ischemic myocardium.
    The American surgeon, 1990, Volume: 56, Issue:8

    Topics: Anesthetics; Animals; Chloralose; Coronary Circulation; Dogs; Female; Male; Myocardial Infarction; M

1990
Comparison of effects of three anesthetic agents on induction of ventricular tachycardia in a canine model of myocardial infarction.
    Circulation, 1988, Volume: 78, Issue:1

    Topics: Animals; Dogs; Droperidol; Drug Combinations; Electric Stimulation; Electrophysiology; Fentanyl; Hal

1988
Left ventricular catecholamines during acute myocardial infarction in the dog.
    Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:2

    Topics: Anesthesia; Animals; Catecholamines; Coronary Disease; Dogs; Dopamine; Epinephrine; Myocardial Infar

1987
Difference in the relation between infarct and occluded bed in pentobarbital-anesthetized and conscious dogs.
    Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:3

    Topics: Anesthesia; Animals; Blood Pressure; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Vess

1986
Mechanisms of remote myocardial dysfunction during coronary artery occlusion in the presence of multivessel disease.
    Circulation, 1986, Volume: 74, Issue:3

    Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Dogs; Hemodynamics; Myocardial Cont

1986
Anesthetics influence myocardial infarct size.
    Advances in myocardiology, 1985, Volume: 6

    Topics: Anesthetics; Animals; Coronary Circulation; Coronary Vessels; Dogs; Fentanyl; Halothane; Heart Rate;

1985
Observations on the mechanisms of infarction in the dog after experimental occlusion of the coronary artery.
    Lancet (London, England), 1966, Jun-11, Volume: 1, Issue:7450

    Topics: Animals; Blood Circulation; Blood Flow Velocity; Collateral Circulation; Coronary Vessels; Dogs; Ele

1966
Experimental graded "pump failure" of the left ventricle.
    The Journal of surgical research, 1971, Volume: 11, Issue:7

    Topics: Animals; Aorta, Thoracic; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Cardiac Output; Cardi

1971
Heart injury after blunt thoracic trauma: an experimental study on rabbits.
    Acta chirurgica Scandinavica. Supplementum, 1968, Volume: 380

    Topics: Animals; Aorta; Aortic Rupture; Blood Pressure Determination; Body Weight; Bradycardia; Bundle-Branc

1968
Experimental coronary artery thrombosis for production of cardiogenic shock.
    Canadian journal of surgery. Journal canadien de chirurgie, 1970, Volume: 13, Issue:2

    Topics: Anesthesia; Animals; Arteries; Blood Pressure; Bretylium Compounds; Cardiac Catheterization; Cardiac

1970
Influence of hypoxia and coronary ligation on cardiac arrest in dogs anaesthetized with pentobarbitone.
    British journal of anaesthesia, 1969, Volume: 41, Issue:4

    Topics: Anesthesia, Intravenous; Animals; Coronary Vessels; Dogs; Electrocardiography; Female; Heart Arrest;

1969
Aortic pressure loading in dogs with myocardial infarction.
    American heart journal, 1969, Volume: 77, Issue:1

    Topics: Animals; Aorta; Blood Pressure; Cardanolides; Cardiac Catheterization; Cardiac Output; Coronary Vess

1969
Myocardial temperature changes in acute experimental infarction.
    Laboratory investigation; a journal of technical methods and pathology, 1966, Volume: 15, Issue:12

    Topics: Animals; Body Temperature; Coronary Disease; Cyanosis; Dogs; Electrocardiography; Female; Heart; Mal

1966