pentobarbital has been researched along with Burns in 8 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Isoflurane (ISO), ketamine-xylazine (KX), or pentobarbital (PEN) with or without buprenorphine were administered before scald-burn in 72 rats that were euthanized without anesthesia by decapitation after 24 h and compared with unburned shams." | 3.76 | Impact of anesthesia, analgesia, and euthanasia technique on the inflammatory cytokine profile in a rodent model of severe burn injury. ( Al-Mousawi, AM; Branski, LK; Herndon, DN; Jeschke, MG; Kraft, R; Kulp, GA; Mecott, GA; Williams, FN, 2010) |
| " Compared with pair-fed control rats, pentobarbital demonstrated a significantly prolonged clearance and elimination half-life without a change in volume of distribution." | 1.27 | Pharmacokinetics of pentobarbital, quinidine, lidocaine, and theophylline in the thermally injured rat. ( DiGregorio, GJ; Fruncillo, RJ, 1984) |
| "It has been suggested that acute respiratory distress syndrome (ARDS) is induced by a cybernetic imbalance of the central nervous system secondary to alarm reaction-provoked intravascular coagulation into cerebral microvessels." | 1.27 | Acute respiratory distress syndrome (ARDS): the prophylactic effect of neurodepressant agents. ( de Oliveira Antonio, MP; de Oliveira, GG; Shimano, LT, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Mousawi, AM | 1 |
| Kulp, GA | 1 |
| Branski, LK | 1 |
| Kraft, R | 1 |
| Mecott, GA | 1 |
| Williams, FN | 1 |
| Herndon, DN | 1 |
| Jeschke, MG | 1 |
| BRAASCH, D | 1 |
| Fruncillo, RJ | 1 |
| DiGregorio, GJ | 1 |
| Agadzhanov, MI | 1 |
| Melik-Agaian, EA | 1 |
| Barton, RN | 1 |
| de Oliveira, GG | 1 |
| Shimano, LT | 1 |
| de Oliveira Antonio, MP | 1 |
| Lewis, GP | 1 |
| Jelenko, C | 1 |
| Jennings, WD | 1 |
| O'Kelley, WR | 1 |
| Byrd, HC | 1 |
8 other studies available for pentobarbital and Burns
| Article | Year |
|---|---|
Impact of anesthesia, analgesia, and euthanasia technique on the inflammatory cytokine profile in a rodent model of severe burn injury.
Topics: Acute-Phase Reaction; Analgesia; Analgesics; Anesthesia, General; Anesthetics; Animals; Buprenorphin | 2010 |
[DECREASED ERYTHROCYTE FLEXIBILITY (INDUCED BY BARBITURATES, BURNS, HYPOXEMIA) AND THEIR EFFECT ON CAPILLARY CIRCULATION].
Topics: Animals; Barbiturates; Blood Volume Determination; Burns; Capillaries; Dogs; Erythrocytes; Hypoxia; | 1963 |
Pharmacokinetics of pentobarbital, quinidine, lidocaine, and theophylline in the thermally injured rat.
Topics: Animals; Burns; Dialysis; Kinetics; Lidocaine; Male; Pentobarbital; Quinidine; Rats; Rats, Inbred St | 1984 |
[Combined effect of anesthesia and burn injuries on lipid peroxidation].
Topics: Anesthesia, General; Animals; Burns; Ether; Female; Lipid Metabolism; Pentobarbital; Peroxides; Rats | 1978 |
Effect of limb ischaemia and scalding on the concentrations of growth hormone and corticosterone in rat plasma.
Topics: Animals; Burns; Corticosterone; Growth Hormone; Hindlimb; Ischemia; Male; Pentobarbital; Rats | 1977 |
Acute respiratory distress syndrome (ARDS): the prophylactic effect of neurodepressant agents.
Topics: Animals; Burns; Central Nervous System Depressants; Chlorpromazine; Diazepam; Dogs; Haloperidol; Hum | 1986 |
Changes in the composition of rabbit hind limb lymph after thermal injury.
Topics: Anesthesia, Intravenous; Animals; Burns; Catheterization; Cytoplasm; Freezing; Hindlimb; Lymph; Lymp | 1969 |
Threshold burning effects on distant microcirculation. I. Preliminary observations.
Topics: Animals; Burns; Capillaries; Capillary Resistance; Male; Microcirculation; Omentum; Pentobarbital; R | 1971 |