pentobarbital has been researched along with Brain Disorders in 15 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seizures were detected in 19% (n = 110) of patients who underwent cEEG monitoring; the seizures were exclusively nonconvulsive in 92% (n = 101) of these patients." | 2.42 | Detection of electrographic seizures with continuous EEG monitoring in critically ill patients. ( Claassen, J; Emerson, RG; Hirsch, LJ; Kowalski, RG; Mayer, SA, 2004) |
| "Although the underlying cause of Reye syndrome is not understood, an effective approach to treatment is based on reversing the known metabolic and pathological abnormalities." | 2.36 | Treatment of Reye syndrome. ( Trauner, DA, 1980) |
| "Pentobarbital treatment reduced 2-DG accumulation in all brain areas examined and these reductions were not influenced by the nBM lesions." | 1.27 | Deoxyglucose uptake and choline acetyltransferase activity in cerebral cortex following lesions of the nucleus basalis magnocellularis. ( Fibiger, HC; Lamarca, MV, 1984) |
| " Three of the seven patients were given a dosage of medication and exceeding the manufacture's recommendation." | 1.26 | Toxic encephalopathy related to antihistamine-barbiturate antiemetic medication. ( Patterson, JH; Schwartz, JF, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (73.33) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HOAKEN, PC | 1 |
| KANE, FJ | 1 |
| SUZUKI, K | 1 |
| KOREY, SR | 1 |
| TERRY, RD | 1 |
| Claassen, J | 1 |
| Mayer, SA | 1 |
| Kowalski, RG | 1 |
| Emerson, RG | 1 |
| Hirsch, LJ | 1 |
| Piatt, JH | 1 |
| Schiff, SJ | 1 |
| Lamarca, MV | 1 |
| Fibiger, HC | 1 |
| Trauner, DA | 1 |
| Schwartz, JF | 1 |
| Patterson, JH | 1 |
| Bosatra, A | 1 |
| Russolo, M | 1 |
| Araki, T | 1 |
| Kato, H | 1 |
| Kogure, K | 1 |
| Inoue, T | 1 |
| Oldfield, EH | 1 |
| Friedman, R | 1 |
| Kinsella, T | 1 |
| Moquin, R | 1 |
| Olson, JJ | 1 |
| Orr, K | 1 |
| DeLuca, AM | 1 |
| Skolnick, A | 1 |
| Lockhart, CH | 1 |
| Hayes, JP | 1 |
| Hackett, PR | 1 |
| Shapiro, HM | 1 |
| Wyte, SR | 1 |
| Loeser, J | 1 |
| Potondi, A | 1 |
| Csalay, L | 1 |
| Klemm, WR | 1 |
| Mallo, GL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective Trial of Nonconvulsive Electrographic Seizure Detection by Nurses in the Adult Neuro ICU Using a Panel of Quantitative EEG Trends[NCT02082873] | 20 participants (Actual) | Observational | 2015-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for pentobarbital and Brain Disorders
| Article | Year |
|---|---|
Detection of electrographic seizures with continuous EEG monitoring in critically ill patients.
Topics: Adult; Aged; Anticonvulsants; Brain Diseases; Child; Child, Preschool; Cohort Studies; Coma; Conscio | 2004 |
Treatment of Reye syndrome.
Topics: Brain Diseases; Humans; Intracranial Pressure; Pentobarbital; Reye Syndrome | 1980 |
13 other studies available for pentobarbital and Brain Disorders
| Article | Year |
|---|---|
Unusual brain syndrome seen with diphenylhydantoin and pentobarbital.
Topics: Brain; Brain Diseases; Humans; Pentobarbital; Phenytoin | 1963 |
STUDIES ON PROTEIN SYNTHESIS IN BRAIN MICROSOMAL SYSTEM.
Topics: Amino Acids; Biomedical Research; Brain; Brain Diseases; Brain Neoplasms; Dementia; Electrons; Ether | 1964 |
High dose barbiturate therapy in neurosurgery and intensive care.
Topics: Barbiturates; Brain; Brain Diseases; Brain Edema; Brain Ischemia; Cerebrovascular Circulation; Criti | 1984 |
Deoxyglucose uptake and choline acetyltransferase activity in cerebral cortex following lesions of the nucleus basalis magnocellularis.
Topics: Alzheimer Disease; Animals; Basal Ganglia; Brain Diseases; Cerebral Cortex; Choline O-Acetyltransfer | 1984 |
Toxic encephalopathy related to antihistamine-barbiturate antiemetic medication.
Topics: Brain Diseases; Child, Preschool; Drug Combinations; Female; Humans; Infant; Male; Pentobarbital; Py | 1978 |
Directional hearing, temporal order and auditory pattern in peripheral and brain stem lesions.
Topics: Auditory Pathways; Auditory Perception; Brain Diseases; Brain Stem; Hearing; Hearing Disorders; Hear | 1976 |
Regional neuroprotective effects of pentobarbital on ischemia-induced brain damage.
Topics: Animals; Behavior, Animal; Brain Diseases; Brain Ischemia; Calcium; Corpus Striatum; Gerbillinae; Hi | 1990 |
Reduction in radiation-induced brain injury by use of pentobarbital or lidocaine protection.
Topics: Animals; Brain; Brain Diseases; Dose-Response Relationship, Radiation; Lidocaine; Monitoring, Physio | 1990 |
Primate study suggests pentobarbital may help protect the brain during radiation therapy.
Topics: Animals; Brain Diseases; Macaca mulatta; Male; Pentobarbital; Radiation Injuries, Experimental; Radi | 1990 |
Hypertensive encephalopathy following urological surgery.
Topics: Atropine; Blood Urea Nitrogen; Brain Diseases; Chlorides; Creatinine; Fever; Halothane; Humans; Hydr | 1973 |
Barbiturate-augmented hypothermia for reduction of persistent intracranial hypertension.
Topics: Adolescent; Blood Pressure; Brain Diseases; Brain Neoplasms; Child; Child, Preschool; Coma; Cranioce | 1974 |
[Effect of alcohol on experimentally induced cerebral hypoxia].
Topics: Animals; Brain Chemistry; Brain Diseases; Cats; Chloral Hydrate; Ethanol; Hypoxia; Pentobarbital; Ra | 1972 |
Clinical electroencephalography in anesthetized small animals.
Topics: Anesthesia; Animals; Brain Diseases; Cat Diseases; Cats; Dog Diseases; Dogs; Electroencephalography; | 1966 |