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pentobarbital and Brain Dead

pentobarbital has been researched along with Brain Dead in 7 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Research Excerpts

ExcerptRelevanceReference
"The diagnosis of brain death and the implications of pentobarbital intoxication during a brain death examination are discussed."1.35Head injuries, pentobarbital, and the determination of death. ( McCutcheon, JR; Molina, DK; Rulon, JJ, 2009)
"The certainty of brain death diagnosis can be enhanced by demonstrating that the concentrations of such drugs are well below the therapeutic range."1.33More reliable brain death diagnosis with chromatographic analysis of midazolam, diazepam, thiopentone, and active metabolites. ( Halwachs-Baumann, G; Mangge, H; März, W; Meinitzer, A, 2006)
"Pentobarbital concentration was evaluated in the brain tissues of brain-dead rabbits."1.30Changes in brain barbiturate concentration in brain-dead rabbits. ( Osawa, M; Saito, T; Takeichi, S; Yukawa, N, 1998)
"In the present two cases of brain death a large amount of barbiturate remained in the brain, even when the blood concentration was not detectable, possibly because the blood flow was stagnant in the brain."1.29Influence of antemortem medication on the determination of brain death. ( Nakajima, Y; Osawa, M; Saito, T; Takeichi, S; Yukawa, N, 1995)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's3 (42.86)18.2507
2000's3 (42.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Meinitzer, A2
Kalcher, K1
Gartner, G1
Halwachs-Baumann, G2
März, W2
Stettin, M1
Molina, DK1
McCutcheon, JR1
Rulon, JJ1
Mangge, H1
Saito, T2
Takeichi, S2
Nakajima, Y1
Yukawa, N2
Osawa, M2
Masukawa, T1
Tochino, Y1
Mantz, JM1
Tempe, JD1
Jaeger, A1
Kurtz, D1
Lobstein, A1
Mack, G1

Other Studies

7 other studies available for pentobarbital and Brain Dead

ArticleYear
Drugs and brain death diagnostics: determination of drugs capable of inducing EEG zero line.
    Clinical chemistry and laboratory medicine, 2008, Volume: 46, Issue:12

    Topics: Anesthetics, Intravenous; Brain Death; Central Nervous System Depressants; Chromatography, High Pres

2008
Head injuries, pentobarbital, and the determination of death.
    The American journal of forensic medicine and pathology, 2009, Volume: 30, Issue:1

    Topics: Accidents, Traffic; Adolescent; Adult; Brain Death; Coma; Female; Forensic Pathology; Head Injuries,

2009
More reliable brain death diagnosis with chromatographic analysis of midazolam, diazepam, thiopentone, and active metabolites.
    Journal of analytical toxicology, 2006, Volume: 30, Issue:3

    Topics: Benzodiazepines; Brain Death; Chromatography, High Pressure Liquid; Humans; Pentobarbital; Thiopenta

2006
Influence of antemortem medication on the determination of brain death.
    Nihon hoigaku zasshi = The Japanese journal of legal medicine, 1995, Volume: 49, Issue:6

    Topics: Adolescent; Brain; Brain Death; Child, Preschool; Coma; Craniocerebral Trauma; Diagnosis, Differenti

1995
Changes in brain barbiturate concentration in brain-dead rabbits.
    Nihon hoigaku zasshi = The Japanese journal of legal medicine, 1998, Volume: 52, Issue:3

    Topics: Animals; Brain; Brain Death; Electroencephalography; Evoked Potentials, Auditory, Brain Stem; Hypnot

1998
Circadian periodicity in the duration of decapitation-induced gasping in mice.
    Japanese journal of pharmacology, 1991, Volume: 57, Issue:3

    Topics: Animals; Body Temperature; Brain Death; Brain Ischemia; Circadian Rhythm; Ethanol; Hypothermia, Indu

1991
[24-hour cerebral electric silence during a massive poisoning with 10g of pentobarbital. Hemodialysis cure].
    La Presse medicale, 1971, May-29, Volume: 79, Issue:27

    Topics: Brain Death; Coma; Electroencephalography; Electroretinography; Female; Fluoroscopy; Humans; Middle

1971