pentobarbital has been researched along with Bradyarrhythmia in 27 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Substance P (SP) evokes bradycardia that is mediated by cholinergic neurons in experiments with isolated guinea pig hearts." | 7.70 | Substance P evokes bradycardia by stimulation of postganglionic cholinergic neurons. ( Hancock, JC; Hoover, DB; Tompkins, JD, 1999) |
| " Time to achieve recumbency, LORR, quiescent electromyograph, isoelectric electrocorticograph, heart rate and apnea were recorded." | 3.83 | Assessment of Carbon Dioxide, Carbon Dioxide/Oxygen, Isoflurane and Pentobarbital Killing Methods in Adult Female Sprague-Dawley Rats. ( Chisholm, JM; Pang, DS, 2016) |
| " However, activation of a discrete region of the MM at the level of the caudal pole of the facial nucleus (CP7) consistently caused a dramatic reduction in phrenic nerve amplitude and/or frequency and, in six rats, produced a prolonged apnea." | 3.72 | A mapping study of cardiorespiratory responses to chemical stimulation of the midline medulla oblongata in ventilated and freely breathing rats. ( Goodchild, AK; Pilowsky, PM; Verner, TA, 2004) |
| "Substance P (SP) evokes bradycardia that is mediated by cholinergic neurons in experiments with isolated guinea pig hearts." | 3.70 | Substance P evokes bradycardia by stimulation of postganglionic cholinergic neurons. ( Hancock, JC; Hoover, DB; Tompkins, JD, 1999) |
| " Apnea followed by rapid shallow breathing was observed in most animals." | 3.66 | Cardiovascular and respiratory responses to right atrial injections of phenyl diguanide in pentobarbital-anesthetized newborn piglets. ( Gootman, N; Gootman, PM; Schleman, M, 1979) |
| "In pentobarbital-treated rats, the sensitivity of the cardiovascular system to nicotine was decreased; in these rats, consecutive nicotine doses did show tachyphylaxis for the pressor and tachycardiac responses." | 1.29 | Cardiovascular effects of different schedules of nicotine administration on spinal rats: influence of pentobarbital. ( Cruz, SL; Fernández-Guasti, A; Villarreal, JE, 1994) |
| "Complications, including fatal cardiac arrhythmias, have been greatly reduced by anesthetic protocols and surgical procedures developed through experience." | 1.27 | Anatomic and anesthetic considerations in experimental cardiopulmonary surgery in swine. ( Baumgartner, WA; Borkon, AM; Galloway, E; Gardner, TJ; Gott, VL; Hall, TS; Horneffer, PJ; Reitz, BA; Stuart, RS; Swindle, MM, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (66.67) | 18.7374 |
| 1990's | 6 (22.22) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chisholm, JM | 1 |
| Pang, DS | 1 |
| ABIKO, Y | 1 |
| BISCOE, TJ | 1 |
| MILLAR, RA | 1 |
| MIETTINEN, P | 1 |
| EEROLA, R | 1 |
| POENTINEN, P | 1 |
| MITHOEFER, JC | 1 |
| KAZEMI, H | 1 |
| HENDLEY, CD | 1 |
| SPUDIS, EV | 1 |
| DELATORRE, E | 1 |
| Verner, TA | 1 |
| Goodchild, AK | 1 |
| Pilowsky, PM | 1 |
| Mason, KP | 1 |
| Zurakowski, D | 1 |
| Zgleszewski, SE | 1 |
| Robson, CD | 1 |
| Carrier, M | 1 |
| Hickey, PR | 1 |
| Dinardo, JA | 1 |
| Cruz, SL | 1 |
| Fernández-Guasti, A | 1 |
| Villarreal, JE | 1 |
| De Wildt, DJ | 1 |
| Van der Ven, JC | 1 |
| Van Bergen, P | 1 |
| De Lang, H | 1 |
| Versteeg, DH | 1 |
| Tompkins, JD | 1 |
| Hoover, DB | 1 |
| Hancock, JC | 1 |
| Alter, WA | 1 |
| Hawkins, RN | 1 |
| Parkhurst, LJ | 1 |
| Poulin, S | 1 |
| Padgett, D | 1 |
| Fink, D | 1 |
| Schleman, M | 1 |
| Gootman, N | 1 |
| Gootman, PM | 1 |
| Myers, RE | 1 |
| de La Coussaye, JE | 1 |
| Bassoul, BP | 1 |
| Albat, B | 1 |
| Peray, PA | 1 |
| Gagnol, JP | 1 |
| Eledjam, JJ | 1 |
| Sassine, A | 1 |
| Bedran-de-Castro, MT | 1 |
| Farah, VM | 1 |
| Krieger, EM | 1 |
| Wang, YX | 1 |
| Pang, CC | 1 |
| Swindle, MM | 1 |
| Horneffer, PJ | 1 |
| Gardner, TJ | 1 |
| Gott, VL | 1 |
| Hall, TS | 1 |
| Stuart, RS | 1 |
| Baumgartner, WA | 1 |
| Borkon, AM | 1 |
| Galloway, E | 1 |
| Reitz, BA | 1 |
| Lehr, E | 2 |
| Werner, G | 2 |
| Greenberg, S | 1 |
| Englebrecht, JA | 1 |
| Wilson, WR | 1 |
| Ambre, J | 1 |
| Thomas, MR | 1 |
| Calaresu, FR | 1 |
| Levy, MN | 1 |
| Blattberg, B | 1 |
| Morishima, HO | 1 |
| Hyman, AI | 1 |
| Adamsons, K | 1 |
| James, LS | 1 |
| Chiba, S | 1 |
| Nakajima, T | 1 |
| Louhimo, I | 1 |
| Evers, W | 1 |
| Racz, GB | 1 |
| Dobkin, AB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Dexmedetomidine of Gastrointestinal Motility[NCT04798482] | Phase 4 | 22 participants (Actual) | Interventional | 2021-09-14 | Completed | ||
| Utility of Oral Dexmedetomidine as the Sole Sedative Agent in Pediatric Population Undergoing MRI[NCT05619627] | Phase 1 | 120 participants (Anticipated) | Interventional | 2024-02-01 | Not yet recruiting | ||
| An Observer-blinded Randomized Study of Propofol Infusion vs Bolus Dexmedetomidine and Propofol Sedation for Pediatric Magnetic Resonance Imaging[NCT03513757] | Phase 4 | 40 participants (Actual) | Interventional | 2018-03-04 | Completed | ||
| A Comparison of Two Doses of Intranasal Dexmedetomidine for Premedication in Children - a Double- Blind Randomised Controlled Trial[NCT02459509] | Phase 4 | 140 participants (Anticipated) | Interventional | 2015-06-30 | Recruiting | ||
| Effect of Increasing Depth of Dexmedetomidine and Propofol Anesthesia on Upper Airway Morphology in Children With History of Obstructive Sleep Apnea[NCT01344759] | Phase 4 | 60 participants (Actual) | Interventional | 2009-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Pediatric Anesthesia Emergence Delirium (PAED) score greater than 12 as defined by Sikich and Lerman. 0 = no delirium, 20 = worst possible delirium; 5 categories scored from 0-4 additive for a maximum score of 20. Categories 1-3 are scored the same and categories ar scored inversely as described. 1. Child makes contact with caregiver, 2. child's actions are purposeful, 3. child is aware of his surroundings. For each of these category, score 0 for extremely, 1 for very much, 2 for quite a bit, 3 for just a little, 4 for not at all. The other 2 categories 4. Child is restless and 5 Child is inconsolable are scored as 0 for not at all, 1 for just a little, 2 for quite a bit, 3 for very much, 4 for extremely (NCT03513757)
Timeframe: up to 24 hours.
| Intervention | participants (Number) |
|---|---|
| Propofol | 0 |
| Propofol Dexmedetomidine | 0 |
dexmedetomidine dose (mcg/kg) (NCT03513757)
Timeframe: up to 90 minutes
| Intervention | mcg/kg (Median) |
|---|---|
| Propofol | 0 |
| Propofol Dexmedetomidine | 0.70 |
minutes from completion of scan to discharge ready (NCT03513757)
Timeframe: up to 2 hours
| Intervention | minutes (Median) |
|---|---|
| Propofol | 40 |
| Propofol Dexmedetomidine | 17 |
Time (minutes) from anesthesia start to readiness for discharge from the department to home or clinic. (NCT03513757)
Timeframe: through study completion, an average of 2 hours
| Intervention | minutes (Median) |
|---|---|
| Propofol | 98 |
| Propofol Dexmedetomidine | 77 |
minutes from completion of scan to spontaneous eye opening (NCT03513757)
Timeframe: up to 90 minutes
| Intervention | minutes (Median) |
|---|---|
| Propofol | 28 |
| Propofol Dexmedetomidine | 3 |
glycopyrrolate dose (mcg/kg) (NCT03513757)
Timeframe: 5 minutes
| Intervention | mcg/kg (Median) |
|---|---|
| Propofol | 0 |
| Propofol Dexmedetomidine | 4.2 |
behavior deemed inappropriate and a deviation from child's normal though parental observation obtained through follow-up phone call (NCT03513757)
Timeframe: up to 48 hours
| Intervention | participants (Number) |
|---|---|
| Propofol | 3 |
| Propofol Dexmedetomidine | 0 |
lidocaine dose (mg/kg) (NCT03513757)
Timeframe: up to 90 minutes
| Intervention | mg/kg (Median) |
|---|---|
| Propofol | 1.00 |
| Propofol Dexmedetomidine | 1.00 |
documentation of use (NCT03513757)
Timeframe: up to 10 minutes
| Intervention | participants (Number) |
|---|---|
| Propofol | 18 |
| Propofol Dexmedetomidine | 17 |
minutes from completion of scan to oral/enteral intake (NCT03513757)
Timeframe: up to 2 hours
| Intervention | minutes (Median) |
|---|---|
| Propofol | 33 |
| Propofol Dexmedetomidine | 14 |
sevoflurane induction time of 5 minutes (NCT03513757)
Timeframe: sevoflurane induction time up to 10 minutes
| Intervention | participants (Number) |
|---|---|
| Propofol | 18 |
| Propofol Dexmedetomidine | 17 |
parental observation of deviation from child's normal habit obtained through follow-up phone call (NCT03513757)
Timeframe: up to 48 hours
| Intervention | participants (Number) |
|---|---|
| Propofol | 3 |
| Propofol Dexmedetomidine | 2 |
total propofol administered (mg/kg) (NCT03513757)
Timeframe: up to 90 minutes
| Intervention | mg/kg (Median) |
|---|---|
| Propofol | 10.6 |
| Propofol Dexmedetomidine | 3.0 |
This is the count of the number of patients who needed an artificial airway. (NCT01344759)
Timeframe: During MRI and until recovery room discharge - approximately 30-250 minutes
| Intervention | Number of artifical airway events (Number) |
|---|---|
| Mild OSA and Dexmedetomidine | 0 |
| Mild OSA and Propofol | 1 |
| Moderate OSA and Dexmedetomidine | 1 |
| Moderate OSA and Propofol | 1 |
| Severe OSA and Dexmedetomidine | 2 |
| Severe OSA and Propofol | 5 |
The Obstructive Index is a count of the obstructive apnea events per hour of sleep (NCT01344759)
Timeframe: During MRI and until recovery room discharge - approximately 30-250 minutes
| Intervention | Apnea events/hour of sleep (Mean) |
|---|---|
| Mild OSA and Dexmedetomidine | 4.2 |
| Mild OSA and Propofol | 3.0 |
| Moderate OSA and Dexmedetomidine | 8.0 |
| Moderate OSA and Propofol | 8.0 |
| Severe OSA and Dexmedetomidine | 16.7 |
| Severe OSA and Propofol | 17.1 |
The respiratory disturbance index is a count of respiratory disturbance events per hour of sleep. (NCT01344759)
Timeframe: During MRI and until recovery room discharge - approximately 30-250 minutes
| Intervention | respir.disturbance events/hr of sleep (Mean) |
|---|---|
| Mild OSA and Dexmedetomidine | 5.1 |
| Mild OSA and Propofol | 3.2 |
| Moderate OSA and Dexmedetomidine | 8.8 |
| Moderate OSA and Propofol | 7.1 |
| Severe OSA and Dexmedetomidine | 16.6 |
| Severe OSA and Propofol | 25.2 |
The patient's oxygen saturation on room air. (NCT01344759)
Timeframe: During MRI and until recovery room discharge - approximately 30-250 minutes
| Intervention | percentage of SpO2 (Mean) |
|---|---|
| Mild OSA and Dexmedetomidine | 87.2 |
| Mild OSA and Propofol | 88.0 |
| Moderate OSA and Dexmedetomidine | 86.3 |
| Moderate OSA and Propofol | 89.0 |
| Severe OSA and Dexmedetomidine | 84.0 |
| Severe OSA and Propofol | 88.0 |
The primary outcome measures will be the cross sectional area of the pharyngeal airway of the patients measured at two levels soft palate (nasopharyngeal) and base of the tongue (retroglossal). Magnetic resonance images of the airway were obtained during low (1 mcg/kg/hr) and high (3 mcg/kg/hr) doses of DEX or low (100 mcg/kg/m) and high (200 mcg/kg/m) doses of Propofol. All were administered through an intravenous (IV) catheter. (NCT01344759)
Timeframe: during MRI within first 10 minutes of scanning
| Intervention | mm^2 (Median) | |||
|---|---|---|---|---|
| Low Dose Sedative, Nasopharyngeal measurement | High Dose Sedative, Nasopharyngeal measurement | Low Dose Sedative, Retroglossal measurement | High dose sedative, Retroglossal measurement | |
| Dexmedetomidine | 178.5 | 235.4 | 120.9 | 120.5 |
| Propofol | 239.9 | 201.6 | 115.1 | 108.1 |
27 other studies available for pentobarbital and Bradyarrhythmia
| Article | Year |
|---|---|
Assessment of Carbon Dioxide, Carbon Dioxide/Oxygen, Isoflurane and Pentobarbital Killing Methods in Adult Female Sprague-Dawley Rats.
Topics: Adjuvants, Anesthesia; Animals; Apnea; Bradycardia; Carbon Dioxide; Electrocardiography; Electrocort | 2016 |
[Effect of diphenylhydantoin on the toxicity and heart action of strospeside in cats].
Topics: Anesthetics, General; Animals; Bradycardia; Cardiac Glycosides; Cats; Ethers; Heart; Pentobarbital; | 1962 |
THE EFFECT OF HALOTHANE ON CAROTID SINUS BARORECEPTOR ACTIVITY.
Topics: Animals; Bradycardia; Carotid Sinus; Cats; Chloralose; Dogs; Goats; Halothane; Hypotension; Neurophy | 1964 |
EKG CHANGES DURING SURGERY FOR STRABISMUS.
Topics: Adolescent; Anesthesia; Arrhythmias, Cardiac; Bradycardia; Bundle-Branch Block; Cardiac Complexes, P | 1964 |
EFFECT OF CARBON DIOXIDE ON HEART RATE.
Topics: Acidosis; Alkalosis; Animals; Atropine; Blood Gas Analysis; Bradycardia; Carbon Dioxide; Chloralose; | 1964 |
INTRACRANIAL PRESSURE DURING ELECTROSHOCK CONVULSIONS IN THE DOG.
Topics: Blood Pressure; Blood Pressure Determination; Bradycardia; Cerebrovascular Circulation; Dogs; Electr | 1965 |
A mapping study of cardiorespiratory responses to chemical stimulation of the midline medulla oblongata in ventilated and freely breathing rats.
Topics: Adjuvants, Anesthesia; Anesthetics, Intravenous; Animals; Apnea; Bradycardia; Brain Mapping; Glutami | 2004 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
High dose dexmedetomidine as the sole sedative for pediatric MRI.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Bradycardia; Child; Child, Preschool; | 2008 |
Cardiovascular effects of different schedules of nicotine administration on spinal rats: influence of pentobarbital.
Topics: Animals; Blood Pressure; Bradycardia; Decerebrate State; Dose-Response Relationship, Drug; Drug Admi | 1994 |
A hypotensive and bradycardic action of gamma 2-melanocyte-stimulating hormone (gamma 2-MSH) microinjected into the nucleus tractus solitarii of the rat.
Topics: Anesthesia; Animals; Blood Pressure; Bradycardia; Heart Rate; Hypotension; Injections, Intravenous; | 1994 |
Substance P evokes bradycardia by stimulation of postganglionic cholinergic neurons.
Topics: Anesthetics; Animals; Atropine; Autonomic Fibers, Postganglionic; Bradycardia; Chlorisondamine; Chol | 1999 |
Barbiturate depression of neurally mediated reflexes to coronary artery occlusion.
Topics: Animals; Arterial Occlusive Diseases; Blood Pressure; Bradycardia; Cats; Coronary Vessels; Heart Rat | 1979 |
Cardiovascular and respiratory responses to right atrial injections of phenyl diguanide in pentobarbital-anesthetized newborn piglets.
Topics: Anesthesia, Inhalation; Animals; Animals, Newborn; Aorta; Apnea; Biguanides; Blood Pressure; Bradyca | 1979 |
Maternal psychological stress and fetal asphyxia: a study in the monkey.
Topics: Acid-Base Equilibrium; Animals; Animals, Newborn; Asphyxia; Asphyxia Neonatorum; Blood Pressure; Bra | 1975 |
Succinylcholine does not worsen bupivacaine-induced cardiotoxicity in pentobarbital-anaesthetized dogs.
Topics: Anesthesia, Intravenous; Animals; Aorta; Blood Pressure; Bradycardia; Bundle of His; Bupivacaine; Do | 1992 |
Influence of general anesthetics on baroreflex control of circulation.
Topics: Animals; Bradycardia; Chloralose; Heart Rate; Male; Nitroprusside; Pentobarbital; Phenylephrine; Pre | 1990 |
Pressor effect of NG-nitro-L-arginine in pentobarbital-anesthetized rats.
Topics: Anesthesia; Animals; Arginine; Blood Pressure; Bradycardia; Dose-Response Relationship, Drug; Heart | 1990 |
Anatomic and anesthetic considerations in experimental cardiopulmonary surgery in swine.
Topics: Acepromazine; Anesthesia; Animals; Arrhythmias, Cardiac; Bradycardia; Cardiopulmonary Bypass; Cardio | 1986 |
[Influencing of heart rhythm by injection of mescaline into the lateral cerebral ventricle of some mammals].
Topics: Animals; Arrhythmia, Sinus; Autonomic Nervous System; Bradycardia; Cerebral Ventricles; Chlorpromazi | 1970 |
Interaction of pentobarbital anesthesia with digoxin-mediated bradycardia.
Topics: Anesthesia, Intravenous; Animals; Atropine; Blood Pressure; Bradycardia; Chloralose; Digoxin; Dogs; | 1973 |
Localization and function of medullary sites mediating vagal bradycardia in the cat.
Topics: Animals; Bradycardia; Cats; Electric Stimulation; Interneurons; Medulla Oblongata; Neurons; Neurons, | 1974 |
Changes in heart rate induced by bacterial endotoxin.
Topics: Animals; Blood Pressure; Bradycardia; Chloralose; Dogs; Electrocardiography; Endotoxins; Escherichia | 1967 |
Anesthetic management for fetal operation in the subhuman primate.
Topics: Acidosis, Respiratory; Anesthesia, Inhalation; Animals; Anxiety; Arteries; Blood Gas Analysis; Blood | 1971 |
Effect of sodium pentobarbital on the SA nodal activity of the dog heart in vivo.
Topics: Acetylcholine; Animals; Atropine; Bradycardia; Depression, Chemical; Dogs; Female; Heart Rate; Injec | 1972 |
Heart injury after blunt thoracic trauma: an experimental study on rabbits.
Topics: Animals; Aorta; Aortic Rupture; Blood Pressure Determination; Body Weight; Bradycardia; Bundle-Branc | 1968 |
[Mescaline induced bradycardia and its antagonistic modification by chlorpromazine, pentobarbital and scopolamine after injection into lateral cerebral ventricle of mouse].
Topics: Animals; Arrhythmias, Cardiac; Bradycardia; Cerebral Ventricles; Chlorpromazine; Depression, Chemica | 1970 |
A study of plasma potassium and electrocardiographic changes after a single dose of succinylcholine.
Topics: Atropine; Bradycardia; Cardiovascular Diseases; Debridement; Diabetes Complications; Electrocardiogr | 1969 |