pentobarbital has been researched along with Bilirubinemia in 3 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A slower plasma clearance rate and longer elimination half-life were observed in homozygous animals as well as increased overall volumes of pentobarbital distribution." | 5.26 | Effect of hyperbilirubinemia on the pharmacokinetics of pentobarbital in the rat. ( Buice, RG, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Buice, RG | 1 |
| Indacochea-Redmond, N | 1 |
| Witschi, H | 1 |
| Plaa, GL | 2 |
| Becker, BA | 1 |
3 other studies available for pentobarbital and Bilirubinemia
| Article | Year |
|---|---|
Effect of hyperbilirubinemia on the pharmacokinetics of pentobarbital in the rat.
Topics: Animals; Half-Life; Hyperbilirubinemia; Kinetics; Male; Pentobarbital; Rats; Time Factors | 1978 |
Effects of inhibitors of protein and ribonucleic acid synthesis on naphthyliso-thiocyanate-induced hyperbilirubinemia, sulfobromophthalein retention and prolongation of pentobarbital hypnosis.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cycloheximide; Dactinomycin; Depression, Chemical; | 1974 |
Quantitative and temporal delineation of various parameters of liver dysfunction due to alpha-naphthylisothiocyanate.
Topics: Animals; Bile; Bilirubin; Blood; Chromatography, Paper; Hyperbilirubinemia; Liver; Liver Diseases; M | 1965 |