pentobarbital has been researched along with Benign Intracranial Hypertension in 12 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pentobarbital has been used in the majority of the clinical studies." | 2.38 | Management of elevated intracranial pressure. ( LeBlanc, KL; Woster, PS, 1990) |
| "03 L/kg and a terminal half-life of 19." | 1.27 | Pentobarbital pharmacokinetics in patients with severe head injury. ( Blouin, RA; Porter, WH; Rapp, RP; Tibbs, PA; Wermeling, DP, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (66.67) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schwartz, ML | 1 |
| Tator, CH | 1 |
| Rowed, DW | 1 |
| Reid, SR | 1 |
| Meguro, K | 1 |
| Andrews, DF | 1 |
| Algren, JT | 1 |
| Roe, EJ | 1 |
| Rea, GL | 1 |
| Rockswold, GL | 1 |
| Lee, MW | 1 |
| Deppe, SA | 1 |
| Sipperly, ME | 1 |
| Barrette, RR | 1 |
| Thompson, DR | 1 |
| Louis, PT | 1 |
| Goddard-Finegold, J | 1 |
| Fishman, MA | 1 |
| Griggs, JR | 1 |
| Stein, F | 1 |
| Laurent, JP | 1 |
| Hoff, JT | 1 |
| Marshall, L | 1 |
| Woster, PS | 1 |
| LeBlanc, KL | 1 |
| Pittman, T | 1 |
| Bucholz, R | 1 |
| Williams, D | 1 |
| Wermeling, DP | 1 |
| Blouin, RA | 1 |
| Porter, WH | 1 |
| Rapp, RP | 1 |
| Tibbs, PA | 1 |
| Miller, JD | 1 |
| Hayashi, M | 1 |
| Kobayashi, H | 1 |
| Kawano, H | 1 |
| Handa, Y | 1 |
| Kabuto, M | 1 |
2 reviews available for pentobarbital and Benign Intracranial Hypertension
| Article | Year |
|---|---|
The use of barbiturates in the control of intracranial hypertension. Brain Trauma Foundation.
Topics: Barbiturates; Craniocerebral Trauma; Humans; Intracranial Pressure; MEDLINE; Pentobarbital; Pseudotu | 1996 |
Management of elevated intracranial pressure.
Topics: Adrenal Cortex Hormones; Barbiturates; Craniocerebral Trauma; Diuretics; Humans; Pentobarbital; Pseu | 1990 |
10 other studies available for pentobarbital and Benign Intracranial Hypertension
| Article | Year |
|---|---|
The University of Toronto head injury treatment study: a prospective, randomized comparison of pentobarbital and mannitol.
Topics: Adult; Brain Edema; Cerebral Hemorrhage; Hematoma; Humans; Intracranial Pressure; Mannitol; Pentobar | 1984 |
Barbiturate-augmented neurointensive care of intracranial hypertension in meningitis.
Topics: Adolescent; Brain Edema; Humans; Intracranial Pressure; Male; Meningitis, Pneumococcal; Penicillins; | 1983 |
Barbiturate therapy in uncontrolled intracranial hypertension.
Topics: Adolescent; Adult; Brain Injuries; Child; Humans; Intracranial Pressure; Middle Aged; Pentobarbital; | 1983 |
The efficacy of barbiturate coma in the management of uncontrolled intracranial hypertension following neurosurgical trauma.
Topics: Adolescent; Adult; Brain Injuries; Chi-Square Distribution; Child; Coma; Female; Glasgow Coma Scale; | 1994 |
Barbiturates and hyperventilation during intracranial hypertension.
Topics: Acute Disease; Animals; Blood Flow Velocity; Blood Gas Analysis; Cerebrovascular Circulation; Combin | 1993 |
Barbiturates in neurosurgery.
Topics: Animals; Barbiturates; Brain Ischemia; Cats; Cerebral Infarction; Dogs; Haplorhini; Humans; Hypoxia, | 1979 |
Efficacy of barbiturates in the treatment of resistant intracranial hypertension in severely head-injured children.
Topics: Adolescent; Brain Injuries; Child; Child, Preschool; Coma; Humans; Infant; Pentobarbital; Pseudotumo | 1989 |
Pentobarbital pharmacokinetics in patients with severe head injury.
Topics: Adolescent; Adult; Brain Injuries; Female; Humans; Infusions, Intravenous; Intracranial Pressure; Ki | 1987 |
ICP monitoring--current status and future directions.
Topics: Biomechanical Phenomena; Compliance; Humans; Intracranial Pressure; Monitoring, Physiologic; Neurosu | 1987 |
The effects of local intraparenchymal pentobarbital on intracranial hypertension following experimental subarachnoid hemorrhage.
Topics: Animals; Dogs; Hypothalamus, Posterior; Injections; Intracranial Pressure; Medulla Oblongata; Pentob | 1987 |