pentobarbital has been researched along with Asystole in 21 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We recently showed that the glottis is actively closed throughout post-hyperventilation, hypocapnic central apnea in lambs." | 3.69 | Prolonged active glottic closure after barbiturate-induced respiratory arrest in lambs. ( Dalle, D; Diaz, V; Kianicka, I; Leroux, JF; Praud, JP, 1996) |
| "Sudden cardiac arrest (SCA) is a leading cause of mortality worldwide." | 1.91 | Evaluation of transcutaneous near-infrared spectroscopy for early detection of cardiac arrest in an animal model. ( Cheung, A; Christenson, J; Grunau, B; Hogle, K; Khalili, M; Kuo, C; Lingawi, S; Manouchehri, N; Mohseni, A; Raschdorf, K; Shadgan, B; So, K, 2023) |
| "Pentobarbital (PB) is a euthanasia drug in doses of 2 to 10 grams, causing death within 15-30 minutes." | 1.51 | Deliberate Self-poisoning with a Lethal Dose of Pentobarbital with Confirmatory Serum Drug Concentrations: Survival After Cardiac Arrest with Supportive Care. ( Druda, DF; Gone, S; Graudins, A, 2019) |
| "With cardiac arrest as the definition of death, no method of euthanasia killed fetal mice." | 1.32 | Euthanasia of mouse fetuses and neonates. ( Clark, T; Davis, JA; Klaunberg, BA; O'malley, J, 2004) |
| "Asphyxial cardiopulmonary arrest was induced and, after and 8 min cardiac arrest nonintervention interval, a standardized protocol of manual CPR with mechanical ventilation was performed." | 1.30 | Anesthetic regimen effects on a pediatric porcine model of asphyxial arrest. ( Ginn, A; Jasani, MS; Nadkarni, VM; Salzman, SK; Tice, LL, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (57.14) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 3 (14.29) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Raschdorf, K | 1 |
| Mohseni, A | 1 |
| Hogle, K | 1 |
| Cheung, A | 1 |
| So, K | 1 |
| Manouchehri, N | 1 |
| Khalili, M | 1 |
| Lingawi, S | 1 |
| Grunau, B | 1 |
| Kuo, C | 1 |
| Christenson, J | 1 |
| Shadgan, B | 1 |
| Druda, DF | 1 |
| Gone, S | 1 |
| Graudins, A | 1 |
| Knapp, J | 1 |
| Teschendorf, P | 1 |
| Scholz, E | 1 |
| Roewer, J | 1 |
| Russ, N | 1 |
| Böttiger, BW | 1 |
| Popp, E | 1 |
| Miyazawa, S | 1 |
| Shiina, T | 1 |
| Takewaki, T | 1 |
| Shimizu, Y | 1 |
| Lalonde-Robert, V | 1 |
| Desgent, S | 1 |
| Duss, S | 1 |
| Vachon, P | 1 |
| Reid, KH | 1 |
| Paskitti, M | 1 |
| Guo, SZ | 1 |
| Schmelzer, T | 1 |
| Iyer, V | 1 |
| BROOM, B | 1 |
| BRUMLIK, J | 1 |
| MIER, M | 1 |
| PETROVICK, M | 1 |
| JENSEN, HP | 1 |
| STAMAND, AE | 1 |
| EVERSOLE, UH | 1 |
| SIEGEL, JH | 1 |
| SONNENBLICK, EH | 1 |
| Klaunberg, BA | 1 |
| O'malley, J | 1 |
| Clark, T | 1 |
| Davis, JA | 1 |
| Artru, AA | 1 |
| Michenfelder, JD | 1 |
| Praud, JP | 1 |
| Kianicka, I | 1 |
| Diaz, V | 1 |
| Leroux, JF | 1 |
| Dalle, D | 1 |
| Jasani, MS | 1 |
| Salzman, SK | 1 |
| Tice, LL | 1 |
| Ginn, A | 1 |
| Nadkarni, VM | 1 |
| Fell, RH | 1 |
| Gunning, AJ | 1 |
| Bardhan, KD | 1 |
| Triger, DR | 1 |
| Tomlin, PJ | 1 |
| Wood, DW | 1 |
| Downes, JJ | 1 |
| Lecks, HI | 1 |
| Spieckermann, PG | 1 |
| Brückner, J | 1 |
| Kübler, W | 1 |
| Lohr, B | 1 |
| Bretschneider, HJ | 1 |
| Kumar, S | 1 |
| Srivastava, S | 1 |
| Hosein, EA | 1 |
| Koh, TY | 1 |
21 other studies available for pentobarbital and Asystole
| Article | Year |
|---|---|
Evaluation of transcutaneous near-infrared spectroscopy for early detection of cardiac arrest in an animal model.
Topics: Animals; Death, Sudden, Cardiac; Heart Arrest; Models, Animal; Oxygen; Pentobarbital; Spectroscopy, | 2023 |
Deliberate Self-poisoning with a Lethal Dose of Pentobarbital with Confirmatory Serum Drug Concentrations: Survival After Cardiac Arrest with Supportive Care.
Topics: Australia; Cardiopulmonary Resuscitation; Heart Arrest; Humans; Male; Middle Aged; Palliative Care; | 2019 |
Conductance catheter measurement and effect of different anesthetics in a rat model of postresuscitation myocardial dysfunction.
Topics: Anesthetics; Animals; Cardiopulmonary Resuscitation; Disease Models, Animal; Heart Arrest; Heart Fun | 2014 |
Extension of time until cardiac arrest after injection of a lethal dose of pentobarbital in the hibernating Syrian hamster.
Topics: Animals; Cricetinae; Heart Arrest; Hibernation; Male; Mesocricetus; Pentobarbital | 2009 |
Electroencephalographic and physiologic changes after tricaine methanesulfonate immersion of African clawed frogs (Xenopus laevis).
Topics: Aminobenzoates; Anesthesia; Anesthetics; Animals; Brain; Drug Administration Routes; Electroencephal | 2012 |
Experience with ketamine and sodium pentobarbital as anesthetics in a rat model of cardiac arrest and resuscitation.
Topics: Anesthetics, Dissociative; Animals; Brain; Cardiopulmonary Resuscitation; Disease Models, Animal; He | 2003 |
EFFECTS OF AIR, OXYGEN AND 20 PER CENT CARBON DIOXIDE ON THE RABBIT DURING SURFACE COOLING DOWN TO CARDIAC ARREST.
Topics: Air; Animals; Carbon Dioxide; Electrocardiography; Electroencephalography; Heart Arrest; Heart Arres | 1963 |
[EXPERIMENTAL STUDIES ON A FORM OF RESTING TREMOR IN THE EXTREMITIES OF HEALTHY DOGS].
Topics: Apnea; Dogs; Electrocardiography; Electroencephalography; Electromyography; Extremities; Heart Arres | 1964 |
ANESTHESIA AND GASTROINTESTINAL SURGERY.
Topics: Anesthesia; Atropine; Blood Transfusion; Digestive System Surgical Procedures; Electrocardiography; | 1964 |
QUANTIFICATION AND PREDICTION OF MYOCARDIAL FAILURE.
Topics: Barbiturates; Dogs; Heart Arrest; Heart Failure; Heart Function Tests; Myocardium; Pentobarbital; Re | 1964 |
Euthanasia of mouse fetuses and neonates.
Topics: Animals; Animals, Laboratory; Animals, Newborn; Carbon Dioxide; Echocardiography; Euthanasia, Animal | 2004 |
Anoxic cerebral potassium accumulation reduced by phenytoin: mechanism of cerebral protection?
Topics: Animals; Cisterna Magna; Dose-Response Relationship, Drug; Heart Arrest; Hypothermia, Induced; Hypox | 1981 |
Prolonged active glottic closure after barbiturate-induced respiratory arrest in lambs.
Topics: Abdominal Muscles; Aging; Animals; Animals, Newborn; Apnea; Electrodes, Implanted; Electromyography; | 1996 |
Anesthetic regimen effects on a pediatric porcine model of asphyxial arrest.
Topics: Adjuvants, Anesthesia; Anesthesia, General; Anesthetics, Combined; Anesthetics, Dissociative; Anesth | 1997 |
Severe hypothermia as a result of barbiturate overdose complicated by cardiac arrest.
Topics: Adult; Anuria; Electric Countershock; Electrocardiography; Extracorporeal Circulation; Female; Heart | 1968 |
Death in outpatient dental anaesthetic practice.
Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, General; Anesthesia, Local; Anesthetics; An | 1974 |
Anesthetic problems in hereditary muscular abnormalities.
Topics: Anesthesia; Anesthesia, Inhalation; Child; Child, Preschool; Halothane; Heart Arrest; Humans; Inject | 1972 |
The management of respiratory failure in childhood status asthmaticus. Experience with 30 episodes and evolution of a technique.
Topics: Acid-Base Equilibrium; Acidosis; Asthma; Blood Gas Analysis; Cardiac Tamponade; Child; Chlorpromazin | 1968 |
[Preischemic stress and resuscitation time of the heart].
Topics: Adenosine Triphosphate; Anesthesia; Animals; Coronary Vessels; Dogs; Ethyl Ethers; Halothane; Heart | 1969 |
Influence of hypoxia and coronary ligation on cardiac arrest in dogs anaesthetized with pentobarbitone.
Topics: Anesthesia, Intravenous; Animals; Coronary Vessels; Dogs; Electrocardiography; Female; Heart Arrest; | 1969 |
The influence of deep narcosis on the content of substances with acetylcholine-like activity in the heart of the rat.
Topics: Acetylcholine; Acyltransferases; Anesthesia; Animals; Carnitine; Ethanol; Heart Arrest; In Vitro Tec | 1966 |