pentobarbital has been researched along with Ascorbic Acid Deficiency in 2 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Ascorbic Acid Deficiency: A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. As the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of hemorrhage. Ascorbic acid deficiency frequently develops into SCURVY in young children fed unsupplemented cow's milk exclusively during their first year. It develops also commonly in chronic alcoholism. (Cecil Textbook of Medicine, 19th ed, p1177)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pentobarbital action is increased under conditions of ascorbic acid deficiency, and this may have to be taken into account when anesthetizing malnourished patients." | 3.80 | Ascorbic acid reverses the prolonged anesthetic action of pentobarbital in Akr1a-knockout mice. ( Fujii, J; Ito, J; Konno, T; Kurahashi, T; Matsuoka, Y; Miyata, S; Otsuki, N; Takahashi, M; Yamada, K; Yamato, M; Zhang, X, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ito, J | 1 |
| Otsuki, N | 1 |
| Zhang, X | 1 |
| Konno, T | 1 |
| Kurahashi, T | 1 |
| Takahashi, M | 1 |
| Yamato, M | 1 |
| Matsuoka, Y | 1 |
| Yamada, K | 1 |
| Miyata, S | 1 |
| Fujii, J | 1 |
| Zannoni, VG | 1 |
| Lynch, MM | 1 |
1 review available for pentobarbital and Ascorbic Acid Deficiency
| Article | Year |
|---|---|
The role of ascorbic acid in drug metabolism.
Topics: Aminopyrine N-Demethylase; Aniline Compounds; Animals; Anisoles; Ascorbic Acid; Ascorbic Acid Defici | 1973 |
1 other study available for pentobarbital and Ascorbic Acid Deficiency
| Article | Year |
|---|---|
Ascorbic acid reverses the prolonged anesthetic action of pentobarbital in Akr1a-knockout mice.
Topics: Adjuvants, Anesthesia; Aldehyde Reductase; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Female; | 2014 |