Page last updated: 2024-11-02

pentobarbital and Arrhythmias, Cardiac

pentobarbital has been researched along with Arrhythmias, Cardiac in 56 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.

Research Excerpts

ExcerptRelevanceReference
"To determine the type of atrial fibrillation induced by use of 2 pacing protocols during fentanyl and pentobarbital anesthesia before and after administration of atropine and to determine the organization of electrical activity in the left and right atria during atrial fibrillation in German Shepherd Dogs."7.74Evaluation of atrial fibrillation induced during anesthesia with fentanyl and pentobarbital in German Shepherd Dogs with inherited arrhythmias. ( Farver, TB; Flanders, JA; Gelzer, AR; Gilmour, RF; Hemsley, SA; Koetje, BD; Kraus, MS; Moïse, NS; Otani, NF; Pariaut, R, 2008)
"Using canine coronary artery ligation/reperfusion and adrenaline arrhythmia models, we determined the effects of azimilide, a class III antiarrhythmic agent, E-1-[[(5-(4-chlorophenyl)-2-furanyl) methylene]-amino]-3-[4-(4-methyl-1-piperazinyl)butyl]-2,4-imidazolidi nedione dihydrochloride."7.70Effects of azimilide, a KV(r) and KV(s) blocker, on canine ventricular arrhythmia models. ( Chino, D; Hashimoto, K; Xue, Y; Yamada, C, 1999)
"The severity and incidences of arrhythmias induced by left coronary artery occlusion (7 min) and reperfusion (7 min) were compared in two groups of rats anaesthetized by using urethane (1."7.69Comparison of sodium pentobarbitone and urethane anaesthesia in a rat model of coronary artery occlusion and reperfusion arrhythmias: interaction with L-NAME. ( Guc, MO; Iskit, AB, 1996)
"We investigated the incidence of ventricular arrhythmias, extent of myocardial infarction and alteration in haemodynamic parameters during 30 minutes of coronary arterial occlusion in rabbits anaesthetized with halothane, alpha chloralose and pentobarbitone."7.68Arrhythmias, haemodynamic changes and extent of myocardial damage during coronary ligation in rabbits anaesthetized with halothane, alpha chloralose or pentobarbitone. ( Chakrabarty, S; Sheridan, DJ; Thomas, P, 1991)
"Changes in the electrocardiogram following bilateral common carotid arteries ligation was observed during the awake state and pentobarbital anesthesia; and the influences of cerebral ischemia, pentobarbital or halothane anesthesia on the cardiotoxicity induced by continuous infusion of ouabain were also studied in Mongolian gerbils."7.68[Experimental study on arrhythmias induced by cerebral ischemia and ouabain in Mongolian gerbils]. ( Maruyama, Y; Nakamura, T, 1991)
"The effect of halothane on arrhythmias induced by ischaemia was investigated in rats, isolated perfused rat hearts, and pigs."7.67Effects of halothane on arrhythmias induced by myocardial ischaemia. ( MacLeod, BA; McGroarty, R; Morton, RH; Walker, MJ, 1989)
"The effect of hypocapnia (PCO2ET 25 vs 40 torr) on specialized atrioventricular (AV) conduction, supraventricular refractory periods, and experimental atrial arrhythmias provoked by premature atrial stimulation (atrial echoes-echoes, repetitive atrial firing (RAF)) was assessed in dogs anesthetized with pentobarbital or pentobarbital-halothane (1."7.66Mechanical hyperventilation: effect on specialized atrioventricular conduction, supraventricular refractoriness, and experimental atrial arrhythmias in dogs anesthetized with pentobarbital or pentobarbital-halothane. ( Ammendrup, P; Atlee, JL, 1980)
"Ephedrine alkaloids-free Ephedra Herb extract (EFE) has been developed to eliminate the adverse effects caused by ephedrine alkaloid-induced sympathetic hyperactivation."5.48Ephedrine Alkaloids-Free Ephedra Herb Extract, EFE, Has No Adverse Effects Such as Excitation, Insomnia, and Arrhythmias. ( Amakura, Y; Goda, Y; Hakamatsuka, T; Hanawa, T; Hyuga, M; Hyuga, S; Kobayashi, Y; Maruyama, T; Odaguchi, H; Oshima, N; Takahashi, J; Takemoto, H; Uchiyama, N; Yamashita, T, 2018)
"Effects upon arrhythmias, blood pressure, heart rate, mortality, ECG and the size of the occluded zone were determined for each drug in the presence of each anaesthetic."5.27Effects of prostaglandin E2, propranolol and nitroglycerine with halothane, pethidine or pentobarbitone anaesthesia on arrhythmias and other responses to ligation of a coronary artery in rats. ( Au, TL; Collins, GA; Macleod, BA; Walker, MJ, 1983)
"Fatal arrhythmias occurred in all mice given 50 mg/kg doxorubicin under ether anesthesia."5.27Acute doxorubicin-induced cardiac arrhythmias during ether anesthesia. ( Aversano, RC; Boor, PJ, 1983)
" Pentobarbital had no effect on arrhythmias, whereas thiopental was antiarrhythmic."3.76Comparison of thiopental, urethane, and pentobarbital in the study of experimental cardiology in rats in vivo. ( Bialka, S; Krzeminski, TF; Mitrega, K; Porc, M; Zorniak, M, 2010)
"To determine the type of atrial fibrillation induced by use of 2 pacing protocols during fentanyl and pentobarbital anesthesia before and after administration of atropine and to determine the organization of electrical activity in the left and right atria during atrial fibrillation in German Shepherd Dogs."3.74Evaluation of atrial fibrillation induced during anesthesia with fentanyl and pentobarbital in German Shepherd Dogs with inherited arrhythmias. ( Farver, TB; Flanders, JA; Gelzer, AR; Gilmour, RF; Hemsley, SA; Koetje, BD; Kraus, MS; Moïse, NS; Otani, NF; Pariaut, R, 2008)
"Using canine coronary artery ligation/reperfusion and adrenaline arrhythmia models, we determined the effects of azimilide, a class III antiarrhythmic agent, E-1-[[(5-(4-chlorophenyl)-2-furanyl) methylene]-amino]-3-[4-(4-methyl-1-piperazinyl)butyl]-2,4-imidazolidi nedione dihydrochloride."3.70Effects of azimilide, a KV(r) and KV(s) blocker, on canine ventricular arrhythmia models. ( Chino, D; Hashimoto, K; Xue, Y; Yamada, C, 1999)
"The severity and incidences of arrhythmias induced by left coronary artery occlusion (7 min) and reperfusion (7 min) were compared in two groups of rats anaesthetized by using urethane (1."3.69Comparison of sodium pentobarbitone and urethane anaesthesia in a rat model of coronary artery occlusion and reperfusion arrhythmias: interaction with L-NAME. ( Guc, MO; Iskit, AB, 1996)
"8 g/kg), and a contribution of diazepam with ketamine hydrochloride (D+K, 10 + 100 mg/kg) anesthesia on the incidence of ischemia/ reperfusion-induced arrhythmias in rats."3.69Influence of anesthetics on the incidence of reperfusion-induced arrhythmias and sudden death in rats. ( Baczkó, I; Leprán, I; Papp, JG, 1997)
"Changes in the electrocardiogram following bilateral common carotid arteries ligation was observed during the awake state and pentobarbital anesthesia; and the influences of cerebral ischemia, pentobarbital or halothane anesthesia on the cardiotoxicity induced by continuous infusion of ouabain were also studied in Mongolian gerbils."3.68[Experimental study on arrhythmias induced by cerebral ischemia and ouabain in Mongolian gerbils]. ( Maruyama, Y; Nakamura, T, 1991)
"We investigated the incidence of ventricular arrhythmias, extent of myocardial infarction and alteration in haemodynamic parameters during 30 minutes of coronary arterial occlusion in rabbits anaesthetized with halothane, alpha chloralose and pentobarbitone."3.68Arrhythmias, haemodynamic changes and extent of myocardial damage during coronary ligation in rabbits anaesthetized with halothane, alpha chloralose or pentobarbitone. ( Chakrabarty, S; Sheridan, DJ; Thomas, P, 1991)
"The effect of halothane on arrhythmias induced by ischaemia was investigated in rats, isolated perfused rat hearts, and pigs."3.67Effects of halothane on arrhythmias induced by myocardial ischaemia. ( MacLeod, BA; McGroarty, R; Morton, RH; Walker, MJ, 1989)
"The effect of hypocapnia (PCO2ET 25 vs 40 torr) on specialized atrioventricular (AV) conduction, supraventricular refractory periods, and experimental atrial arrhythmias provoked by premature atrial stimulation (atrial echoes-echoes, repetitive atrial firing (RAF)) was assessed in dogs anesthetized with pentobarbital or pentobarbital-halothane (1."3.66Mechanical hyperventilation: effect on specialized atrioventricular conduction, supraventricular refractoriness, and experimental atrial arrhythmias in dogs anesthetized with pentobarbital or pentobarbital-halothane. ( Ammendrup, P; Atlee, JL, 1980)
"The effects of asphyxia and potassium on the electrocardiogram (ECG), lead II, were recorded from dogs and cats anesthetized with sodium pentobarbital and halothane."3.65Effects of asphyxia and potassium on canine and feline electrocardiograms. ( Coulter, DB; Duncan, RJ; Sander, PD, 1975)
"Breathing a mixture of 75 percent helium and 25 percent oxygen instead of 75 percent nitrogen and 25 percent oxygen reduced the occurrence of dangerous cardiac arrhythmias after ligation of the circumflex coronary artery in open-chest dogs anesthetized with pentobarbital."3.65Possible mechanism for the antiarrhythmic effect of helium in anesthetized dogs. ( Eger, EI; Goldfien, A; Halsey, MJ; Raymond, L; Severinghaus, JW; Weiskopf, RB, 1972)
"Ephedrine alkaloids-free Ephedra Herb extract (EFE) has been developed to eliminate the adverse effects caused by ephedrine alkaloid-induced sympathetic hyperactivation."1.48Ephedrine Alkaloids-Free Ephedra Herb Extract, EFE, Has No Adverse Effects Such as Excitation, Insomnia, and Arrhythmias. ( Amakura, Y; Goda, Y; Hakamatsuka, T; Hanawa, T; Hyuga, M; Hyuga, S; Kobayashi, Y; Maruyama, T; Odaguchi, H; Oshima, N; Takahashi, J; Takemoto, H; Uchiyama, N; Yamashita, T, 2018)
"The incidence of reperfusion arrhythmias (100%) was similar in hearts of control and previously anesthetized rats, but the duration of the arrhythmias was significantly increased by anesthesia (5-fold with thiopental, 15-fold with pentobarbital, ether and halothane, and 30-fold with urethane)."1.29Effects of anesthetics on the incidence and duration of reperfusion arrhythmias in isolated rat heart. ( Almeida, AP; Freire-Maia, L; Goes, S, 1993)
" During dosing (10 mg kg-1 twice a day for 10 days) no effects on the electrocardiogram, monitored in conscious animals, were observed despite modest reductions (15-18%) in the maximum rate of depolarization of papillary muscle excised 1 or 6 h after completion of the dosing regime."1.28Antiarrhythmic, electrophysiological and haemodynamic effects of prolonged oral dosing with Org 7797 in the anaesthetized rat. ( Delbressine, L; Harris, N; Kane, KA; Muir, AW; Winslow, E, 1992)
" Three minutes after pretreatment, group 1 (n = 11), group 3 (n = 10), and their respective control groups (n = 11 and n = 9) received intravenous bupivacaine LD50 (median lethal dose)."1.28Nimodipine reduces the toxicity of intravenous bupivacaine in rats. ( Horn, JL; Hyman, SA; Kambam, JR; Kinney, WW; Skelley, CC, 1992)
"Potentiation of bupivacaine arrhythmia in myocyte cultures suggests that this effect is at least partly mediated at the myocyte level."1.28Progesterone potentiation of bupivacaine arrhythmogenicity in pentobarbital-anesthetized rats and beating rat heart cell cultures. ( Baum, VC; Curran, MA; Miletich, DJ, 1992)
"Fatal arrhythmias occurred in all mice given 50 mg/kg doxorubicin under ether anesthesia."1.27Acute doxorubicin-induced cardiac arrhythmias during ether anesthesia. ( Aversano, RC; Boor, PJ, 1983)
"Effects upon arrhythmias, blood pressure, heart rate, mortality, ECG and the size of the occluded zone were determined for each drug in the presence of each anaesthetic."1.27Effects of prostaglandin E2, propranolol and nitroglycerine with halothane, pethidine or pentobarbitone anaesthesia on arrhythmias and other responses to ligation of a coronary artery in rats. ( Au, TL; Collins, GA; Macleod, BA; Walker, MJ, 1983)
"Complications, including fatal cardiac arrhythmias, have been greatly reduced by anesthetic protocols and surgical procedures developed through experience."1.27Anatomic and anesthetic considerations in experimental cardiopulmonary surgery in swine. ( Baumgartner, WA; Borkon, AM; Galloway, E; Gardner, TJ; Gott, VL; Hall, TS; Horneffer, PJ; Reitz, BA; Stuart, RS; Swindle, MM, 1986)
"Thus, reperfusion arrhythmias after a 15 minute occlusion of the left anterior descending coronary artery were compared in 24 open chest dogs (17 anesthetized with pentobarbital and 7 with chloralose plus urethane) and 25 conscious, unsedated, trained dogs."1.27Disparity of reperfusion arrhythmias after reversible myocardial ischemia in open chest and conscious dogs. ( Bolli, R; Myers, ML; Roberts, R; Zhu, WX, 1986)
"Few arrhythmias were produced at the maximum administered infusion rate during pentobarbital anesthesia (2 of 6 with epinephrine, 3 of 6 with dopamine, and 0 of 6 administered dobutamine)."1.27Catecholamine infusion in vagotomized dogs during thiamylal-halothane and pentobarbital anesthesia. ( Bednarski, RM; Muir, WW, 1985)
"This model for malignant hyperpyrexia resembles the naturally occurring disease more closely than several preceding pharmacologic models."1.26A laboratory animal model for malignant hyperpyrexia. ( Durbin, CG; Rosenberg, H, 1979)
"Epinephrine-induced ventricular arrhythmia observed in C1 744-anesthetized animals was eliminated in cats and was markedly reduced in dogs by bilateral vagotomy."1.25Absence of sensitization to epinephrine-induced cardiac arrhythmia and fibrillation in dogs and cats anesthetized with CI 744. ( Pettway, CE; Smith, RD, 1975)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199037 (66.07)18.7374
1990's14 (25.00)18.2507
2000's2 (3.57)29.6817
2010's3 (5.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takemoto, H1
Takahashi, J1
Hyuga, S1
Odaguchi, H1
Uchiyama, N1
Maruyama, T1
Yamashita, T1
Hyuga, M1
Oshima, N1
Amakura, Y1
Hakamatsuka, T1
Goda, Y1
Hanawa, T1
Kobayashi, Y1
Shekarforoush, S1
Fatahi, Z1
Safari, F1
Pariaut, R1
Moïse, NS1
Koetje, BD1
Flanders, JA1
Hemsley, SA1
Farver, TB1
Gilmour, RF1
Gelzer, AR1
Kraus, MS1
Otani, NF1
Zorniak, M1
Mitrega, K1
Bialka, S1
Porc, M1
Krzeminski, TF1
MIETTINEN, P1
EEROLA, R1
POENTINEN, P1
SEKIYA, A1
VAUGHANWILLIAMS, EM1
Zhang, Y1
Wang, L1
Katz, RL2
Lord, CO1
Eakins, KE1
Au, TL1
Collins, GA1
Macleod, BA2
Walker, MJ3
Aversano, RC1
Boor, PJ1
Sumikawa, K1
Ishizaka, N1
Suzaki, M1
Ammendrup, P1
Atlee, JL1
de La Coussaye, JE1
Eledjam, JJ1
Bruelle, P1
Peray, PA1
Bassoul, BP1
Gagnol, JP1
Sassine, A1
Goes, S1
Freire-Maia, L1
Almeida, AP1
Iskit, AB1
Guc, MO1
Baczkó, I1
Leprán, I1
Papp, JG1
Jung, JW1
Koch, GG1
Xue, Y1
Yamada, C1
Chino, D1
Hashimoto, K1
Durbin, CG1
Rosenberg, H1
Miletich, DJ2
Albrecht, RF1
Seals, C1
Andersen, JR1
Eikard, B1
Bhargava, KP1
Srivastava, VK1
Barthwal, JP1
Sinha, JN1
Ticzon, AR1
Strauss, HC1
Gallagher, JJ1
Wallace, AG1
Smith, RD1
Pettway, CE1
Coulter, DB1
Duncan, RJ1
Sander, PD1
Baum, VC1
Curran, MA1
Delbressine, L1
Harris, N1
Kane, KA1
Muir, AW1
Winslow, E1
Hyman, SA1
Kinney, WW2
Horn, JL1
Skelley, CC1
Kambam, JR2
Nakamura, T1
Maruyama, Y1
Chakrabarty, S1
Thomas, P1
Sheridan, DJ1
Matsuda, F1
Wright, W1
Howard, PG1
Segal, J1
Schwalb, H1
Shmorak, V1
Uretzky, G1
Dai, S1
Manning, AS1
Crome, R1
Klein, N1
Hearse, DJ1
Maguire, ME1
McGroarty, R1
Morton, RH1
Swindle, MM1
Horneffer, PJ1
Gardner, TJ1
Gott, VL1
Hall, TS1
Stuart, RS1
Baumgartner, WA1
Borkon, AM1
Galloway, E1
Reitz, BA1
Bolli, R1
Myers, ML1
Zhu, WX1
Roberts, R1
Puddu, PE1
Jouve, R1
Guillen, JC1
Langlet, F1
Noirclerc, M1
Reale, A1
Torresani, J1
Mazzoni, P1
Giffin, JP1
Cottrell, JE1
Hartung, J1
Capuano, C1
Epstein, JM1
Bednarski, RM1
Muir, WW1
Vick, JA1
Shipman, WH1
Brooks, R1
Heeg, E1
Greeff, K1
Sakai, K1
Sugano, S1
Isono, C1
Chopdar, A1
Hinds, L1
Kaul, B1
Calabro, J1
Hutcheon, DE1
Holland, JA1
Wolfe, WG1
Kylstra, JA1
Thompson, EB1
Baldoni, F1
Tallarida, G1
Peruzzi, G1
Sangiorgi, M1
Stickney, JL1
Arora, RB1
Bagchi, N1
Gupta, OP1
Raymond, L1
Weiskopf, RB1
Halsey, MJ1
Goldfien, A1
Eger, EI1
Severinghaus, JW1
Kiba, T1
Madan, BR1
Khanna, NK1
Jain, BK1
Lehr, E1
Werner, G1

Trials

1 trial available for pentobarbital and Arrhythmias, Cardiac

ArticleYear
Arrhythmias during halothane anesthesia. III. The influence of barbiturates.
    Acta anaesthesiologica Scandinavica, 1978, Volume: 22, Issue:4

    Topics: Adult; Aged; Anesthesia, General; Arrhythmias, Cardiac; Blood Pressure; Carbon Dioxide; Halothane; H

1978

Other Studies

55 other studies available for pentobarbital and Arrhythmias, Cardiac

ArticleYear
Ephedrine Alkaloids-Free Ephedra Herb Extract, EFE, Has No Adverse Effects Such as Excitation, Insomnia, and Arrhythmias.
    Biological & pharmaceutical bulletin, 2018, Volume: 41, Issue:2

    Topics: Alkaloids; Analgesics, Non-Narcotic; Animals; Animals, Outbred Strains; Anxiety; Arrhythmias, Cardia

2018
The effects of pentobarbital, ketamine-pentobarbital and ketamine-xylazine anesthesia in a rat myocardial ischemic reperfusion injury model.
    Laboratory animals, 2016, Volume: 50, Issue:3

    Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Hemodynamics; Ketamine; Male; Myocardial Reperfusion Inj

2016
Evaluation of atrial fibrillation induced during anesthesia with fentanyl and pentobarbital in German Shepherd Dogs with inherited arrhythmias.
    American journal of veterinary research, 2008, Volume: 69, Issue:11

    Topics: Action Potentials; Anesthetics, Intravenous; Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Atr

2008
Comparison of thiopental, urethane, and pentobarbital in the study of experimental cardiology in rats in vivo.
    Journal of cardiovascular pharmacology, 2010, Volume: 56, Issue:1

    Topics: Adjuvants, Anesthesia; Anesthetics, Intravenous; Animals; Arrhythmias, Cardiac; Blood Pressure; Dise

2010
EKG CHANGES DURING SURGERY FOR STRABISMUS.
    Acta ophthalmologica, 1964, Volume: 42

    Topics: Adolescent; Anesthesia; Arrhythmias, Cardiac; Bradycardia; Bundle-Branch Block; Cardiac Complexes, P

1964
CENTRAL AND PERIPHRAL ACTIONS OF PRONETHALOL.
    British journal of pharmacology and chemotherapy, 1965, Volume: 24

    Topics: Arrhythmias, Cardiac; Blood Pressure; Chloroform; Electrocardiography; Epinephrine; Ethanolamines; E

1965
Increased coronary flow may prolong transmural ventricular repolarisation.
    Medical hypotheses, 2006, Volume: 67, Issue:4

    Topics: Action Potentials; Adjuvants, Anesthesia; Animals; Arrhythmias, Cardiac; Coronary Circulation; Elect

2006
Anesthetic-dopamine cardiac arrhythmias and their prevention by beta adrenergic blockade.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Cyclopropanes; Dopamine; Drug Synergism; Femora

1967
Effects of prostaglandin E2, propranolol and nitroglycerine with halothane, pethidine or pentobarbitone anaesthesia on arrhythmias and other responses to ligation of a coronary artery in rats.
    British journal of pharmacology, 1983, Volume: 79, Issue:4

    Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Coronary Vessels; Dinoprostone; Drug Interactions; Halot

1983
Acute doxorubicin-induced cardiac arrhythmias during ether anesthesia.
    Research communications in chemical pathology and pharmacology, 1983, Volume: 41, Issue:2

    Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Doxorubicin; Electrocardiography; Ether; Ethyl E

1983
Arrhythmogenic plasma levels of epinephrine during halothane, enflurane, and pentobarbital anesthesia in the dog.
    Anesthesiology, 1983, Volume: 58, Issue:4

    Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Dogs; Enflurane; Epinephrine; Female; Halothane;

1983
Mechanical hyperventilation: effect on specialized atrioventricular conduction, supraventricular refractoriness, and experimental atrial arrhythmias in dogs anesthetized with pentobarbital or pentobarbital-halothane.
    Anesthesia and analgesia, 1980, Volume: 59, Issue:11

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Dogs; Halothane; Heart Conduction System; Hyperventilatio

1980
Electrophysiologic and arrhythmogenic effects of the potassium channel agonist BRL 38227 in anesthetized dogs.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:5

    Topics: Anesthesia; Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Benzopyrans; Cromakalim; Dogs; D

1993
Effects of anesthetics on the incidence and duration of reperfusion arrhythmias in isolated rat heart.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1993, Volume: 26, Issue:10

    Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Male; Myocardial Reperfusion; Pentobarbital; Rats; Rats,

1993
Comparison of sodium pentobarbitone and urethane anaesthesia in a rat model of coronary artery occlusion and reperfusion arrhythmias: interaction with L-NAME.
    Pharmacological research, 1996, Volume: 33, Issue:1

    Topics: Adjuvants, Anesthesia; Anesthetics, Intravenous; Animals; Arrhythmias, Cardiac; Arterial Occlusive D

1996
Influence of anesthetics on the incidence of reperfusion-induced arrhythmias and sudden death in rats.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:2

    Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Death, Sudden; Diazepam; Hemodynamics; Ketamine; Male; M

1997
Multivariate non-parametric methods for Mann-Whitney statistics to analyse cross-over studies with two treatment sequences.
    Statistics in medicine, 1999, Apr-30, Volume: 18, Issue:8

    Topics: Animals; Arrhythmias, Cardiac; Clinical Protocols; Cross-Over Studies; Female; Heart Rate; Least-Squ

1999
Effects of azimilide, a KV(r) and KV(s) blocker, on canine ventricular arrhythmia models.
    European journal of pharmacology, 1999, Jul-02, Volume: 376, Issue:1-2

    Topics: Anesthetics; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Epinephrine; Female; Halot

1999
A laboratory animal model for malignant hyperpyrexia.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 210, Issue:1

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Caffeine; Disease Models, Animal; Drug Interactions; Halo

1979
Responses to fasting and lipid infusion of epinephrine-induced arrhythmias during halothane anesthesia.
    Anesthesiology, 1978, Volume: 48, Issue:4

    Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Epinephrine; Fasting; Fatty Acids; Fatty Acids,

1978
Significance of spinal autonomic loci in post coronary ligation arrhythmia.
    Neuropharmacology, 1976, Volume: 15, Issue:10

    Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Catecholamines; Chloralose; Chlorisondamine

1976
Sinus nodal function in the intact dog heart evaluated by premature atrial stimulation and atrial pacing.
    The American journal of cardiology, 1975, Volume: 35, Issue:4

    Topics: Anesthesia, Intravenous; Animals; Arrhythmias, Cardiac; Atrial Function; Chloralose; Dogs; Electric

1975
Absence of sensitization to epinephrine-induced cardiac arrhythmia and fibrillation in dogs and cats anesthetized with CI 744.
    American journal of veterinary research, 1975, Volume: 36, Issue:5

    Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Anesthetics, Diss

1975
Effects of asphyxia and potassium on canine and feline electrocardiograms.
    Canadian journal of comparative medicine : Revue canadienne de medecine comparee, 1975, Volume: 39, Issue:4

    Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Arrhythmias, Cardiac; Asphyxia; Blood Pres

1975
Progesterone potentiation of bupivacaine arrhythmogenicity in pentobarbital-anesthetized rats and beating rat heart cell cultures.
    Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:4

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Bupivacaine; Cells, Cultured; Drug Synergism; Epinephrine

1992
Antiarrhythmic, electrophysiological and haemodynamic effects of prolonged oral dosing with Org 7797 in the anaesthetized rat.
    The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:12

    Topics: Action Potentials; Administration, Oral; Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, C

1992
Nimodipine reduces the toxicity of intravenous bupivacaine in rats.
    Anesthesia and analgesia, 1992, Volume: 74, Issue:6

    Topics: Animals; Apnea; Arrhythmias, Cardiac; Body Weight; Bupivacaine; Cardiovascular System; Drug Interact

1992
[Experimental study on arrhythmias induced by cerebral ischemia and ouabain in Mongolian gerbils].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1991, Volume: 98, Issue:5

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Blood Pressure; Brain; Brain Ischemia; Electrocardiograph

1991
Arrhythmias, haemodynamic changes and extent of myocardial damage during coronary ligation in rabbits anaesthetized with halothane, alpha chloralose or pentobarbitone.
    International journal of cardiology, 1991, Volume: 31, Issue:1

    Topics: Analysis of Variance; Anesthesia, General; Animals; Arrhythmias, Cardiac; Blood Pressure; Chloralose

1991
Nicardipine reduces the cardio-respiratory toxicity of intravenously administered bupivacaine in rats.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:8

    Topics: Analysis of Variance; Anesthesia, Conduction; Animals; Apnea; Arrhythmias, Cardiac; Bupivacaine; Hea

1990
Electrical stimulation studies with quinacainol, a putative 1C agent, in the anaesthetised rat.
    Proceedings of the Western Pharmacology Society, 1990, Volume: 33

    Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Electric Stimulat

1990
Effect of anesthesia on cardiac function and response in the perfused rat heart.
    Journal of molecular and cellular cardiology, 1990, Volume: 22, Issue:11

    Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Calcium; Heart; Hemodynamics; In Vitro Technique

1990
Anaesthetic-related occurrence of early ventricular arrhythmias during acute myocardial ischaemia in rats.
    Archives internationales de physiologie et de biochimie, 1989, Volume: 97, Issue:5

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Blood Pressure; Chloralose; Coronary Disease; Coronary Ve

1989
Dissociation between reperfusion induced arrhythmias and increases in ventricular alpha 1 receptor density in the anaesthetised rat.
    Cardiovascular research, 1989, Volume: 23, Issue:10

    Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Heart Ventricles; Male; Myocardial Reperfusion Inju

1989
Effects of halothane on arrhythmias induced by myocardial ischaemia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1989, Volume: 36, Issue:3 Pt 1

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Catheterization, Swan-Ganz; Coronary

1989
Anatomic and anesthetic considerations in experimental cardiopulmonary surgery in swine.
    Laboratory animal science, 1986, Volume: 36, Issue:4

    Topics: Acepromazine; Anesthesia; Animals; Arrhythmias, Cardiac; Bradycardia; Cardiopulmonary Bypass; Cardio

1986
Disparity of reperfusion arrhythmias after reversible myocardial ischemia in open chest and conscious dogs.
    Journal of the American College of Cardiology, 1986, Volume: 7, Issue:5

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Chloralose; Coronary Circulation; Coronary Disease; Dogs;

1986
[An anesthetic technic in dogs for studying the arrhythmogenic effects of acute coronary occlusion].
    Journal de physiologie, 1985, Volume: 80, Issue:1

    Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Atropine; Coronary Disease; Coronary Vessels; Di

1985
Intracranial pressure during diltiazem-induced hypotension in anesthetized dogs.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:10

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Benzazepines; Blood Pressure; Cardiac Output; Diltiazem;

1985
Catecholamine infusion in vagotomized dogs during thiamylal-halothane and pentobarbital anesthesia.
    The Cornell veterinarian, 1985, Volume: 75, Issue:4

    Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Blood Pressure; Catecholamines; Dobutamine; Dogs

1985
Beta adrenergic and anti-arrhythmic effects of cardiopep, a newly isolated substance from whole bee venom.
    Toxicon : official journal of the International Society on Toxinology, 1974, Volume: 12, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Anti-Arrhythmia Agents; Arrhythmias

1974
[Analysis of digitalis action by continuous measurement of intraventricular pressure in cats].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 260, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Digoxin; Ouabain; Pentobarbital; Ventricular Fu

1968
Effects of oxyfedrine and ouabain on the heart-lung preparation of the dog.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 277, Issue:1

    Topics: Amino Alcohols; Animals; Arrhythmias, Cardiac; Cardiac Output; Disease Models, Animal; Dogs; Female;

1973
Sedation for cataract surgery. Comparison of Carbrital and neuroleptanalgesia.
    The British journal of ophthalmology, 1970, Volume: 54, Issue:10

    Topics: Aged; Apnea; Arrhythmias, Cardiac; Benperidol; Butyrates; Cataract Extraction; Fentanyl; Humans; Hyp

1970
Dissociation of tracheobronchial and cardiac effects of some beta-adrenergic stimulants.
    Anesthesiology, 1971, Volume: 34, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Bronchi; Bronchial Spasm; Bronchodilator Ag

1971
Effects of carbon monoxide on the vulnerability of the ventricles to drug-induced arrhythmias.
    Journal of clinical pharmacology, 1974, Volume: 14, Issue:1

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Blood Pressure; Carbon Monoxide; Carboxyhemoglobin; Digit

1974
Helium: absence of antiarrhythmic effect in anesthetized dogs.
    The Journal of thoracic and cardiovascular surgery, 1973, Volume: 66, Issue:3

    Topics: Anesthesia, Intravenous; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Carbon Dioxide; Coro

1973
Comparison of degree of susceptibility of hyperthyroid and euthyroid animals to cardiac glycoside-induced arrhythmias.
    Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:10

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Calcium Chloride; Cardiac Glycosides; Guinea Pigs; He

1973
[Changes in the reflex cardiocirculatory and respiratory responses to intracarotid and intrafemoral injection of bradykinin caused by drug blocking of the neurovegetative system].
    Bollettino della Societa italiana di biologia sperimentale, 1973, Feb-15, Volume: 49, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Atropine; Autonomic Nerve Block; Blood Pressure; Bradykinin; Cardiova

1973
The effect of different types of anesthesia on digitalis toxicity.
    American heart journal, 1974, Volume: 87, Issue:6

    Topics: Anesthesia, Intravenous; Anesthetics; Animals; Arrhythmias, Cardiac; Cardanolides; Cats; Chloralose;

1974
The effects of reserpine and propranolol on the therapeutic and toxic effects of peruvoside in the heart-lung preparation and intact dogs.
    The Indian journal of medical research, 1972, Volume: 60, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Cardanolides; Cardiac Glycosides; Dogs; Drug Antagonism; Extracorpore

1972
Possible mechanism for the antiarrhythmic effect of helium in anesthetized dogs.
    Science (New York, N.Y.), 1972, Jun-16, Volume: 176, Issue:4040

    Topics: Anesthesia, General; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Coronary

1972
Effects of thiopental and pentobarbital sodium on the transmembrane potentials of the rabbit's atria in special reference to interaction with catecholamine.
    Japanese journal of pharmacology, 1966, Volume: 16, Issue:4

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Atrial Function; Drug Antagonism; Electrophysiolog

1966
Effect of pentobarbital and thiopental on the acetylcholine content of the heart and brain.
    Indian journal of physiology and pharmacology, 1969, Volume: 13, Issue:4

    Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Cerebral Cortex; Female; Heart Atria; Heart Ventricles

1969
[Mescaline induced bradycardia and its antagonistic modification by chlorpromazine, pentobarbital and scopolamine after injection into lateral cerebral ventricle of mouse].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:7

    Topics: Animals; Arrhythmias, Cardiac; Bradycardia; Cerebral Ventricles; Chlorpromazine; Depression, Chemica

1970