Page last updated: 2024-11-02

pentobarbital and Anxiety

pentobarbital has been researched along with Anxiety in 63 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"Ephedrine alkaloids-free Ephedra Herb extract (EFE) has been developed to eliminate the adverse effects caused by ephedrine alkaloid-induced sympathetic hyperactivation."5.48Ephedrine Alkaloids-Free Ephedra Herb Extract, EFE, Has No Adverse Effects Such as Excitation, Insomnia, and Arrhythmias. ( Amakura, Y; Goda, Y; Hakamatsuka, T; Hanawa, T; Hyuga, M; Hyuga, S; Kobayashi, Y; Maruyama, T; Odaguchi, H; Oshima, N; Takahashi, J; Takemoto, H; Uchiyama, N; Yamashita, T, 2018)
"Formalin-induced acute inflammatory pain was established by intraplantar injection of 1% formalin without anesthesia or with anesthesia using the clinical anesthetics sevoflurane, propofol, or pentobarbital sodium."3.81Differential effects of general anesthetics on anxiety-like behavior in formalin-induced pain: involvement of ERK activation in the anterior cingulate cortex. ( Dai, RP; Li, CQ; Luo, C; Luo, W; Xu, JM; Zhang, YL; Zhou, FH, 2015)
" A crude extract was given systemically and its effects were tested on pentylenetetrazole (PTZ)-induced seizures, sodium pentobarbital-induced hypnosis, exploratory activity, anxiety and nociception."3.73Neuropharmacological profile of an ethanol extract of Ruta chalepensis L. in mice. ( Carrera, D; Cedillo-Portugal, E; Gonzalez-Trujano, ME; Navarrete, A; Ventura-Martinez, R, 2006)
" Both isolated male and female mice showed shorter time in pentobarbital-induced loss of righting reflex and less body weight gain."3.72Sex difference in psychological behavior changes induced by long-term social isolation in mice. ( Chen, D; Guo, M; Liu, W; Wu, CF; Yang, JY, 2004)
") had no depression-like effect in the forced swimming test (FST) in rats; exerted anxiety-like effect in the elevated plus maze test in rats; did not alter the locomotor activity in rats; had no apparent effect on sleep latency but shortened the sleeping time on pentobarbital sleeping time in mice; and showed analgesic activity in acetic acid writhing and hot plate test in mice."3.71Antidepressant, anxiogenic, and antinociceptive properties of levofloxacin in rats and mice. ( Erden, BF; Gacar, N; Ozdemirci, S; Ulak, G; Utkan, T; Yildiz, F, 2001)
", thigmotaxis) was suppressed by anxiolytic agents (diazepam 1-5 mg/kg; chlordiazepoxide 1-10 mg/kg; pentobarbital 1-10 mg/kg), with a relative potency that was similar to their relative potency in the treatment of human anxiety."3.67Thigmotaxis as a test for anxiolytic activity in rats. ( Fundytus, M; Treit, D, 1988)
"Anxiety and depression are often comorbid with neurological as well as other medical maladies."1.56Electronegativity in Substituted-4(H)-quinazolinones Causes Anxiolysis without a Sedative-hypnotic Adverse Reaction in Female Wistar Rats. ( Agarwal, RK; Das, D; Gajbhiye, A; Mishra, S; Patil, S; Sahu, A; Verma, E, 2020)
"Ephedrine alkaloids-free Ephedra Herb extract (EFE) has been developed to eliminate the adverse effects caused by ephedrine alkaloid-induced sympathetic hyperactivation."1.48Ephedrine Alkaloids-Free Ephedra Herb Extract, EFE, Has No Adverse Effects Such as Excitation, Insomnia, and Arrhythmias. ( Amakura, Y; Goda, Y; Hakamatsuka, T; Hanawa, T; Hyuga, M; Hyuga, S; Kobayashi, Y; Maruyama, T; Odaguchi, H; Oshima, N; Takahashi, J; Takemoto, H; Uchiyama, N; Yamashita, T, 2018)
"Rolipram was characterized for its emetic, behavioral, cardiovascular and pulmonary activities in dogs, to assess its systemic pharmacology and potential bronchodilatory selectivity."1.29Emetic, central nervous system, and pulmonary activities of rolipram in the dog. ( Evans, DY; Heaslip, RJ, 1995)
"0 mg/kg AOAA significantly potentiated the effects of diazepam, as indicated by a significant shift to the left in the diazepam dose-response curve relative to diazepam alone."1.27Potentiation of the anticonflict effects of diazepam, but not pentobarbital and phenobarbital, by aminooxyacetic acid (AOAA). ( Beshears, JF; Commissaris, RL; Halas, NA; McCloskey, TC, 1988)

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-199040 (63.49)18.7374
1990's6 (9.52)18.2507
2000's7 (11.11)29.6817
2010's9 (14.29)24.3611
2020's1 (1.59)2.80

Authors

AuthorsStudies
Mishra, S1
Das, D1
Sahu, A1
Verma, E1
Patil, S1
Agarwal, RK1
Gajbhiye, A1
Takemoto, H1
Takahashi, J1
Hyuga, S1
Odaguchi, H1
Uchiyama, N1
Maruyama, T1
Yamashita, T1
Hyuga, M1
Oshima, N1
Amakura, Y1
Hakamatsuka, T1
Goda, Y1
Hanawa, T1
Kobayashi, Y1
Ota, Y1
Ago, Y1
Tanaka, T1
Hasebe, S1
Toratani, Y1
Onaka, Y1
Hashimoto, H1
Takuma, K1
Matsuda, T1
Raud, S1
Reimets, R1
Loomets, M1
Sütt, S1
Altpere, A1
Visnapuu, T1
Innos, J1
Luuk, H1
Plaas, M1
Volke, V1
Vasar, E1
Luo, C1
Zhang, YL1
Luo, W1
Zhou, FH1
Li, CQ1
Xu, JM1
Dai, RP1
dela Peña, IJ1
Hong, E1
de la Peña, JB1
Kim, HJ1
Botanas, CJ1
Hong, YS1
Hwang, YS1
Moon, BS1
Cheong, JH1
Ávila-Villarreal, G1
González-Trujano, ME2
Carballo-Villalobos, AI1
Aguilar-Guadarrama, B1
García-Jiménez, S1
Giles-Rivas, DE1
Castillo-España, P1
Villalobos-Molina, R1
Estrada-Soto, S1
VAN HARREVELD, A1
Estrada-Reyes, R1
López-Rubalcava, C1
Rocha, L1
Heinze, G1
González Esquinca, AR1
Martínez-Vázquez, M1
Shabanov, PD1
Lebedev, AA1
Galdino, PM1
Nascimento, MV1
Florentino, IF1
Lino, RC1
Fajemiroye, JO1
Chaibub, BA1
de Paula, JR1
de Lima, TC2
Costa, EA1
Zanoli, P1
Rivasi, M1
Baraldi, C1
Baraldi, M1
Kliethermes, CL1
Finn, DA1
Crabbe, JC1
CALLOWAY, NO2
BATTEN, CT1
SHAGASS, C1
SCHWARTZ, M1
CRISP, GO1
HARDAWAY, RM1
JOHNSON, DG1
HOUCHIN, DN1
JENKINS, EB1
BURNS, JW1
JACKSON, DR1
HILL, HE1
BELLEVILLE, RE1
WIKLER, A1
Guo, M1
Wu, CF1
Liu, W1
Yang, JY1
Chen, D1
ABRUZZI, WA1
Carrera, D1
Ventura-Martinez, R1
Cedillo-Portugal, E1
Navarrete, A1
Duarte, FS1
Duzzioni, M1
Mendes, BG1
Pizzolatti, MG1
Emmett-Oglesby, M1
Spencer, D1
Lewis, M1
Elmesallamy, F1
Lal, H2
Hovi-Viander, M1
Kangas, L1
Kanto, J1
Francès, H1
Monier, C1
Bourre, JM1
Agmo, A1
Galvan, A1
Heredia, A1
Morales, M1
Wolthuis, OL1
Groen, B1
Philippens, IH1
Heaslip, RJ1
Evans, DY1
Kash, SF1
Tecott, LH1
Hodge, C1
Baekkeskov, S1
Erden, BF1
Ulak, G1
Yildiz, F1
Utkan, T1
Ozdemirci, S1
Gacar, N1
Dockstader, CL1
van der Kooy, D1
Conner, JT1
Parson, N1
Katz, RL1
Wapner, S1
Bellville, JW1
Uhlenhuth, EH1
Dundee, JW1
Nair, SG1
Assaf, RA1
Clarke, RS1
Kernohan, SM1
Fernández-Teruel, A1
Escorihuela, RM1
Núñez, JF1
Zapata, A1
Boix, F1
Salazar, W1
Tobeña, A1
Harris, C1
Goa, KL1
Heel, RC1
Sagratella, S1
Scotti de Carolis, A1
Longo, VG1
Pollard, GT1
Howard, JL1
Miyauchi, T1
Dworkin, SI1
Co, C1
Smith, JE1
McCloskey, TC1
Beshears, JF1
Halas, NA1
Commissaris, RL1
Treit, D1
Fundytus, M1
Kissin, B1
Gross, MM1
Greenberg, R1
Pearlman, C1
Milkovich, L1
van den Berg, BJ1
Grainger, JK1
Feffer, HL1
Fassolt, A1
Egbert, LD1
Mima, T1
Okumura, F1
Onji, H1
Káclová, J1
Haertzen, CA1
Mizuguchi, T1
Zbinden, G1
Randall, LO1
Beattie, IA1
Berry, PA1
Lister, RE1
Morishima, HO1
Hyman, AI1
Adamsons, K1
James, LS1
Vogel, JR1
Beer, B1
Clody, DE1
Marble, HB1
Koppel, AC1
Adams-Koppel, E1
Jones, BE1
Ayres, JJ1
Flanary, HG1
Clements, TH1
Murray, WJ1
Bechtoldt, AA1
Berman, L1
Pietrobono, P1
Venchi, G1
Scotti, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Subanesthetic Sevoflurane for Treatment-Resistant Depression: A Proof-of-Concept Trial[NCT05008939]15 participants (Anticipated)Interventional2021-08-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for pentobarbital and Anxiety

ArticleYear
Zopiclone. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy as an hypnotic.
    Drugs, 1986, Volume: 32, Issue:1

    Topics: Anti-Anxiety Agents; Anticonvulsants; Anxiety; Azabicyclo Compounds; Benzodiazepines; Biotransformat

1986
Cutting the REM nerve: an approach to the adaptive role of REM sleep.
    Perspectives in biology and medicine, 1974,Summer, Volume: 17, Issue:4

    Topics: Adaptation, Psychological; Animals; Anxiety; Avoidance Learning; Defense Mechanisms; Depression; Ele

1974
Psychological support for surgical patients.
    International psychiatry clinics, 1967, Volume: 4, Issue:2

    Topics: Adaptation, Psychological; Anesthesiology; Anxiety; Communication; Defense Mechanisms; Emotions; Hum

1967
[Methods of evaluating preoperative anxiety and the degree of sedation].
    Masui. The Japanese journal of anesthesiology, 1971, Volume: 20, Issue:8

    Topics: Anxiety; Diazepam; Evaluation Studies as Topic; Humans; Hypnotics and Sedatives; Meperidine; Pentoba

1971
Pharmacology of benzodiazepines: laboratory and clinical correlations.
    Advances in pharmacology, 1967, Volume: 5

    Topics: Aggression; Alcoholism; Animals; Anticonvulsants; Anxiety; Autonomic Nervous System; Avoidance Learn

1967

Trials

10 trials available for pentobarbital and Anxiety

ArticleYear
A comparative study of the clinical effects of pentobarbital and diazepam given orally as preoperative medication.
    Journal of oral surgery (American Dental Association : 1965), 1980, Volume: 38, Issue:3

    Topics: Adult; Anxiety; Diazepam; Double-Blind Method; Drug Evaluation; Humans; Middle Aged; Mouth; Pentobar

1980
Evaluation of lorazepam and pentobarbital as surgical premedicants.
    Clinical pharmacology and therapeutics, 1976, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Clinical Trials as Topic; Drug Evaluation; Hu

1976
Pentobarbitone premedication for anaesthesia. The influence of the preparation and route of administration on its clinical action.
    Anaesthesia, 1976, Volume: 31, Issue:8

    Topics: Administration, Oral; Adolescent; Adult; Anxiety; Female; Humans; Injections, Intramuscular; Middle

1976
Double-blind evaluation of diazepam, sodium pentobarbital, and placebo as adjunctive premedicants prior to discography.
    Clinical orthopaedics and related research, 1974, Issue:100

    Topics: Adjuvants, Anesthesia; Adult; Aged; Anxiety; Blood Pressure; Clinical Trials as Topic; Cognition Dis

1974
[The value of peroben, nembutal and valium as hypnosedativa in the praeoperative phase (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1974, Feb-12, Volume: 63, Issue:6

    Topics: Anxiety; Clinical Trials as Topic; Diazepam; Diphenhydramine; Drug Combinations; Drug Evaluation; Hu

1974
[Studies on preoperative anxiety and sleep disorders].
    Masui. The Japanese journal of anesthesiology, 1968, Volume: 17, Issue:1

    Topics: Anxiety; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Pentobarbital; Placebos; Preopera

1968
Premedication with ataractics and barbiturates in anxious patients prior to dental surgery.
    Activitas nervosa superior, 1967, Volume: 9, Issue:4

    Topics: Adult; Aged; Anesthesia, Dental; Anxiety; Benactyzine; Clinical Trials as Topic; Humans; Meprobamate

1967
Subjective effects of narcotic antagonists cyclazocine and nalorphine on the Addiction Research Center Inventory (ARCI).
    Psychopharmacologia, 1970, Volume: 18, Issue:4

    Topics: Academies and Institutes; Analgesics; Analysis of Variance; Anxiety; Azocines; Clinical Trials as To

1970
Effects of morphine and pentobarbital on conditioned electrodermal responses and basal conductance in man.
    Psychopharmacologia, 1965, Mar-15, Volume: 7, Issue:3

    Topics: Adult; Anxiety; Clinical Trials as Topic; Conditioning, Psychological; Cues; Electroshock; Galvanic

1965
Efficacy of oral psychosedative drugs for preanesthetic medication.
    JAMA, 1968, Jan-29, Volume: 203, Issue:5

    Topics: Adult; Age Factors; Anxiety; Body Weight; Diazepam; Ethchlorvynol; Female; Humans; Hydroxyzine; Hypn

1968

Other Studies

48 other studies available for pentobarbital and Anxiety

ArticleYear
Electronegativity in Substituted-4(H)-quinazolinones Causes Anxiolysis without a Sedative-hypnotic Adverse Reaction in Female Wistar Rats.
    Central nervous system agents in medicinal chemistry, 2020, Volume: 20, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Depression; Female; Hypnotics and Sedatives; Lethal Dose 50;

2020
Ephedrine Alkaloids-Free Ephedra Herb Extract, EFE, Has No Adverse Effects Such as Excitation, Insomnia, and Arrhythmias.
    Biological & pharmaceutical bulletin, 2018, Volume: 41, Issue:2

    Topics: Alkaloids; Analgesics, Non-Narcotic; Animals; Animals, Outbred Strains; Anxiety; Arrhythmias, Cardia

2018
Anxiolytic-like effects of restraint during the dark cycle in adolescent mice.
    Behavioural brain research, 2015, May-01, Volume: 284

    Topics: Aging; Animals; Anxiety; Brain; Conditioning, Psychological; Corticosterone; Darkness; Exploratory B

2015
Deletion of the Wolfram syndrome-related gene Wfs1 results in increased sensitivity to ethanol in female mice.
    Neuropharmacology, 2015, Volume: 95

    Topics: Animals; Anxiety; Central Nervous System Depressants; Dose-Response Relationship, Drug; Ethanol; Exp

2015
Differential effects of general anesthetics on anxiety-like behavior in formalin-induced pain: involvement of ERK activation in the anterior cingulate cortex.
    Psychopharmacology, 2015, Volume: 232, Issue:24

    Topics: Anesthetics, Inhalation; Animals; Anxiety; Behavior, Animal; Extracellular Signal-Regulated MAP Kina

2015
Milk Collected at Night Induces Sedative and Anxiolytic-Like Effects and Augments Pentobarbital-Induced Sleeping Behavior in Mice.
    Journal of medicinal food, 2015, Volume: 18, Issue:11

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Cattle; Circadian Rhythm; Hypnotics and Sed

2015
Anxiolytic-like effects and toxicological studies of Brickellia cavanillesii (Cass.) A. Gray in experimental mice models.
    Journal of ethnopharmacology, 2016, Nov-04, Volume: 192

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Asteraceae; Behavior, Animal; Consciousness; Disease Models,

2016
Effect of ether and pentobarbital on the polarisation state of central nervous elements.
    The American journal of physiology, 1947, Oct-01, Volume: 150, Issue:4

    Topics: Anxiety; Ether; Ethers; Humans; Pentobarbital

1947
Anxiolytic-like and sedative actions of Rollinia mucosa: possible involvement of the GABA/benzodiazepine receptor complex.
    Pharmaceutical biology, 2010, Volume: 48, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Dose-Response Relationship, Drug; Drug Synergism; Exploratory

2010
[Behavioral correlations of gradual forced administration of psychoactive drugs].
    Eksperimental'naia i klinicheskaia farmakologiia, 2011, Volume: 74, Issue:6

    Topics: Amphetamine; Animals; Anxiety; Behavior, Animal; Dexamethasone; Dose-Response Relationship, Drug; Dr

2011
The anxiolytic-like effect of an essential oil derived from Spiranthera odoratissima A. St. Hil. leaves and its major component, β-caryophyllene, in male mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2012, Aug-07, Volume: 38, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Male; Mice; Motor Activity; Oils, Volatile;

2012
Pharmacological activity of hyperforin acetate in rats.
    Behavioural pharmacology, 2002, Volume: 13, Issue:8

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Anxiety; Beha

2002
Validation of a modified mirrored chamber sensitive to anxiolytics and anxiogenics in mice.
    Psychopharmacology, 2003, Volume: 169, Issue:2

    Topics: Animals; Animals, Outbred Strains; Anti-Anxiety Agents; Anxiety; Carbolines; Dextroamphetamine; Diaz

2003
Tranquilization and sedation by the use of a combination of small doses of reserpine and pentobarbital sodium.
    The Illinois medical journal, 1956, Volume: 110, Issue:5

    Topics: Anxiety; Humans; Hypertension; Hypnotics and Sedatives; Pentobarbital; Reserpine; Tranquilizing Agen

1956
Tranquilization and sedation by the use of a combination of small doses of reserpine and pentobarbital sodium.
    The Illinois medical journal, 1956, Volume: 110, Issue:5

    Topics: Anxiety; Humans; Hypertension; Hypnotics and Sedatives; Pentobarbital; Reserpine; Tranquilizing Agen

1956
Tranquilization and sedation by the use of a combination of small doses of reserpine and pentobarbital sodium.
    The Illinois medical journal, 1956, Volume: 110, Issue:5

    Topics: Anxiety; Humans; Hypertension; Hypnotics and Sedatives; Pentobarbital; Reserpine; Tranquilizing Agen

1956
Tranquilization and sedation by the use of a combination of small doses of reserpine and pentobarbital sodium.
    The Illinois medical journal, 1956, Volume: 110, Issue:5

    Topics: Anxiety; Humans; Hypertension; Hypnotics and Sedatives; Pentobarbital; Reserpine; Tranquilizing Agen

1956
Long-release barbiturate medication for relief of tension.
    Medical times, 1962, Volume: 90

    Topics: Anxiety; Anxiety Disorders; Barbiturates; Delayed-Action Preparations; Humans; Pentobarbital

1962
NEUROPHYSIOLOGICAL DYSFUNCTION ASSOCIATED WITH SOME PSYCHIATRIC DISORDERS.
    Psychiatric research reports, 1963, Volume: 17

    Topics: Anxiety; Anxiety Disorders; Attention; Cats; Depression; Electroencephalography; Hearing; Humans; Me

1963
A NEW LOOK AT PENTOBARBITAL.
    Western medicine; the medical journal of the west, 1964, Volume: 5

    Topics: Anxiety; Anxiety Disorders; Dementia; Female; Heart Diseases; Humans; Hypertension; Menopause; Neuro

1964
INFLUENCE OF STRESS ON FIBRINOGEN.
    The Journal of trauma, 1964, Volume: 4

    Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Blood Coagulation Disorders; Coagulants; Cortisone; D

1964
Studies on anxiety associated with anticipation of pain. II. Comparative effects of pentobarbital and morphine.
    A.M.A. archives of neurology and psychiatry, 1955, Volume: 73, Issue:6

    Topics: Anxiety; Barbiturates; Humans; Morphine; Pain; Pentobarbital

1955
Sex difference in psychological behavior changes induced by long-term social isolation in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2004, Volume: 28, Issue:1

    Topics: Animals; Anxiety; Behavior, Animal; Body Weight; Female; Helplessness, Learned; Hypnotics and Sedati

2004
A LONG RELEASE DOSE FORM OF PENTOBARBITAL COMPARED WITH MEPROBAMATE IN THE MANAGEMENT OF ANXIETY STATES.
    Clinical medicine (Northfield, Ill.), 1964, Volume: 71

    Topics: Adolescent; Anxiety; Anxiety Disorders; Biomedical Research; Drug Therapy; Humans; Meprobamate; Pati

1964
Neuropharmacological profile of an ethanol extract of Ruta chalepensis L. in mice.
    Journal of ethnopharmacology, 2006, Jun-15, Volume: 106, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Central Nervous System Depressants; Ethanol;

2006
Participation of dihydrostyryl-2-pyrones and styryl-2-pyrones in the central effects of Polygala sabulosa (Polygalaceae), a folk medicine topical anesthetic.
    Pharmacology, biochemistry, and behavior, 2007, Volume: 86, Issue:1

    Topics: Anesthetics, Inhalation; Anesthetics, Local; Animals; Anti-Anxiety Agents; Anxiety; Convulsants; Dio

2007
Anxiogenic aspects of diazepam withdrawal can be detected in animals.
    European journal of pharmacology, 1983, Aug-19, Volume: 92, Issue:1-2

    Topics: Animals; Anxiety; Benzodiazepinones; Diazepam; Discrimination Learning; Flumazenil; Humans; Male; Pe

1983
Effects of dietary alpha-linolenic acid deficiency on neuromuscular and cognitive functions in mice.
    Life sciences, 1995, Volume: 57, Issue:21

    Topics: alpha-Linolenic Acid; Animals; Anxiety; Behavior, Animal; Cognition; Diet; Female; Male; Mice; Motor

1995
Naloxone blocks the antianxiety but not the motor effects of benzodiazepines and pentobarbital: experimental studies and literature review.
    Psychopharmacology, 1995, Volume: 120, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Male; Maze Learning; Motor Activity; Naloxon

1995
A simple automated test to measure exploratory and motor activity of marmosets.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:4

    Topics: Animals; Anxiety; Callithrix; Exploratory Behavior; Female; Male; Methamphetamine; Motor Activity; P

1994
Emetic, central nervous system, and pulmonary activities of rolipram in the dog.
    European journal of pharmacology, 1995, Nov-24, Volume: 286, Issue:3

    Topics: Animals; Anxiety; Asthma; Brain; Bronchi; Dogs; Female; Heart Rate; Male; Nadolol; Pentobarbital; Ph

1995
Increased anxiety and altered responses to anxiolytics in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Feb-16, Volume: 96, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Crosses, Genetic; Diazepam; Female; gamma-Aminobutyric Acid;

1999
Antidepressant, anxiogenic, and antinociceptive properties of levofloxacin in rats and mice.
    Pharmacology, biochemistry, and behavior, 2001, Volume: 68, Issue:3

    Topics: Analgesics; Animals; Anti-Infective Agents; Antidepressive Agents; Anxiety; Hypnotics and Sedatives;

2001
Mouse strain differences in opiate reward learning are explained by differences in anxiety, not reward or learning.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Nov-15, Volume: 21, Issue:22

    Topics: Animals; Anxiety; Behavior, Animal; Cocaine; Conditioning, Psychological; Cues; Diazepam; Dopamine U

2001
Evaluating antianxiety agents in humans: experimental paradigms.
    The American journal of psychiatry, 1977, Volume: 134, Issue:6

    Topics: Anxiety; Avoidance Learning; Chlorpromazine; Conditioning, Operant; Dextroamphetamine; Diazepam; Dru

1977
The early acquisition of two-way (shuttle-box) avoidance as an anxiety-mediated behavior: psychopharmacological validation.
    Brain research bulletin, 1991, Volume: 26, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Azides; Benzodiazepines; Carbolines; Male

1991
Interoceptive stimuli produced by an anxiogenic drug are mimicked by benzodiazepine antagonists in rats pretreated with isoniazid.
    Neuropharmacology, 1985, Volume: 24, Issue:7

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepinones; Brain Chemistry; Convulsants; Discriminati

1985
EEG interaction between delta 8-tetrahydrocannabinol and some sedative-anxiolytic drugs. Is the anxiogenic effect of Cannabis related to an action on the GABAergic system?
    Advances in biochemical psychopharmacology, 1986, Volume: 41

    Topics: Animals; Anxiety; Brain; Cannabis; Diazepam; Dronabinol; Drug Interactions; Electroencephalography;

1986
Effects of chlordiazepoxide, pentobarbital, buspirone, chlorpromazine, and morphine in the stretched attend posture (SAP) test.
    Psychopharmacology, 1988, Volume: 94, Issue:3

    Topics: Animals; Anxiety; Behavior, Animal; Buspirone; Chlordiazepoxide; Chlorpromazine; Male; Mice; Morphin

1988
Specific effects of punishment on amino acids turnover in discrete rat brain regions.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:3

    Topics: Amino Acids; Animals; Anxiety; Aspartic Acid; Behavior, Animal; Brain; Brain Chemistry; Conflict, Ps

1988
Potentiation of the anticonflict effects of diazepam, but not pentobarbital and phenobarbital, by aminooxyacetic acid (AOAA).
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:3

    Topics: Acetates; Aminooxyacetic Acid; Animals; Anxiety; Behavior, Animal; Conflict, Psychological; Diazepam

1988
Thigmotaxis as a test for anxiolytic activity in rats.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:4

    Topics: Animals; Anxiety; Behavior, Animal; Dextroamphetamine; Disease Models, Animal; Male; Morphine; Motor

1988
Drug therapy in alcoholism.
    Current psychiatric therapies, 1970, Volume: 10

    Topics: Adult; Alcoholic Intoxication; Alcoholism; Antidepressive Agents; Anxiety; Carbamates; Chlordiazepox

1970
Effects of prenatal meprobamate and chlordiazepoxide hydrochloride on human embryonic and fetal development.
    The New England journal of medicine, 1974, Dec-12, Volume: 291, Issue:24

    Topics: Abnormalities, Drug-Induced; Aluminum; Anxiety; Child, Preschool; Chlordiazepoxide; Embryo, Mammalia

1974
Perception: its meaning, significance and control in dental procedures. 3. Clinical aspects.
    Australian dental journal, 1972, Volume: 17, Issue:3

    Topics: Analgesia; Anesthesia, Dental; Anxiety; Behavior Therapy; Conditioning, Psychological; Dental Care;

1972
Methods for detecting anti-anxiety drugs using baboons (Papio cynocephalus).
    British journal of pharmacology, 1970, Volume: 38, Issue:2

    Topics: Aggression; Animals; Anxiety; Behavior, Animal; Benzazepines; Chlordiazepoxide; Chlorpromazine; Hapl

1970
Anesthetic management for fetal operation in the subhuman primate.
    American journal of obstetrics and gynecology, 1971, Aug-01, Volume: 110, Issue:7

    Topics: Acidosis, Respiratory; Anesthesia, Inhalation; Animals; Anxiety; Arteries; Blood Gas Analysis; Blood

1971
A simple and reliable conflict procedure for testing anti-anxiety agents.
    Psychopharmacologia, 1971, Volume: 21, Issue:1

    Topics: Animals; Anxiety; Behavior, Animal; Chlordiazepoxide; Conflict, Psychological; Dextroamphetamine; Di

1971
A clinical comparison of sedative agents in surgical preoperative medication.
    U. S. Navy medicine, 1969, Volume: 53, Issue:5

    Topics: Anxiety; Humans; Hydroxyzine; Hypnotics and Sedatives; Pentobarbital; Preanesthetic Medication

1969
A method of intravenous medication.
    Sda Dentist, 1969,Spring, Volume: 2, Issue:3

    Topics: Anxiety; Humans; Injections, Intravenous; Meperidine; Pain; Pentobarbital; Preanesthetic Medication;

1969
[On the use of a new derivative of benzodiazepines (Ro 4-5360) in the treatment of insomnia in pre-surgery patients].
    Minerva anestesiologica, 1969, Volume: 35, Issue:1

    Topics: Anxiety; Diazepam; Glutethimide; Humans; Pentobarbital; Preanesthetic Medication; Preoperative Care;

1969