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pentobarbital and Anoxia, Brain

pentobarbital has been researched along with Anoxia, Brain in 28 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Research Excerpts

ExcerptRelevanceReference
"Effect of minaprine on hypoxia- or hypoxia/hypoglycemia (ischemia)-induced impairment of 2-deoxyglucose (2DG) uptake by rat hippocampal slices was evaluated."7.68Protective effect of minaprine against the abnormal changes of 2-deoxyglucose uptake by rat hippocampal slices induced by hypoxia/hypoglycemia. ( Kodama, K; Shibata, S; Ueki, S, 1992)
"Effect of minaprine on hypoxia- or hypoxia/hypoglycemia (ischemia)-induced impairment of 2-deoxyglucose (2DG) uptake by rat hippocampal slices was evaluated."3.68Protective effect of minaprine against the abnormal changes of 2-deoxyglucose uptake by rat hippocampal slices induced by hypoxia/hypoglycemia. ( Kodama, K; Shibata, S; Ueki, S, 1992)
" Ten EEGs from 10 patients with hypoxic-ischemic encephalopathy (HIE-BS) and 21 records from 8 patients with pentobarbital induced burst-suppression for treatment of status epilepticus (SE-BS) were reviewed."3.68Variance of interburst intervals in burst suppression. ( Beydoun, A; Drury, I; Yen, CE, 1991)
"Tacrine was protective against hypoxia but had no effect on anoxia and ischemia."1.29Protective effect of R(-)-1-(benzo[b]thiophen-5-yl)- 2-[2-(N,N-diethylamino)ethoxy]ethanol hydrochloride (T-588), a novel cerebral activator, against experimental cerebral anoxia. ( Ano, M; Hirata, K; Kitamura, K; Maekawa, M; Narita, H; Ono, S; Ukai, W; Yamafuji, T, 1993)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199024 (85.71)18.7374
1990's3 (10.71)18.2507
2000's1 (3.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
OROSZ, E1
KRUPP, P1
CARPI, A1
Nemoto, EM2
Shiu, GK2
Nemmer, JP1
Bleyaert, AL1
Nemmer, J1
Mei, GS1
Chen, SJ1
Chen, XH1
Wu, DX1
Han, Y1
Karasawa, A1
Kumada, Y1
Yamada, K1
Shuto, K1
Nakamizo, N1
Artru, AA1
Michenfelder, JD3
Mayevsky, A1
Lebourdais, S1
Chance, B1
Ono, S1
Kitamura, K1
Maekawa, M1
Hirata, K1
Ano, M1
Ukai, W1
Yamafuji, T1
Narita, H1
Viapiano, MS1
Mitridate de Novara, AM1
Fiszer de Plazas, S1
Bozzini, CE1
Sundt, TM1
Anderson, RE1
Hoff, JT1
Marshall, L1
Rossowska, M1
Ignelzi, RJ1
Yasuda, H1
Shuto, S1
Tsumagari, T1
Nakajima, A1
Majewska, MD1
Strosznajder, J1
Lazarewicz, J1
Milde, JH1
Kodama, K1
Shibata, S1
Ueki, S1
Beydoun, A1
Yen, CE1
Drury, I1
Berga, P1
Beckett, PR1
Roberts, DJ1
Llenas, J1
Massingham, R1
Krieglstein, J1
Brungs, H1
Peruche, B1
Rivera, VM1
Meyer, JS1
Hata, T1
Ishikawa, Y1
Imai, A1
Aitken, PG1
Schiff, SJ1
Wagner, KR1
Ting, P1
Westfall, MV1
Yamaguchi, S1
Bacher, JD1
Myers, RE1
Bazán, NG1
Buletza, GF1
Quay, WB1
Rosen, MG1
McLaughlin, A1
Goldstein, A1
Wells, BA1
Keats, AS1

Reviews

1 review available for pentobarbital and Anoxia, Brain

ArticleYear
Cerebral protection by anaesthetics during ischaemia: (a review).
    Resuscitation, 1975, Volume: 4, Issue:4

    Topics: Anesthetics; Animals; Barbiturates; Brain; Cerebrovascular Circulation; Dogs; Halothane; Haplorhini;

1975

Other Studies

27 other studies available for pentobarbital and Anoxia, Brain

ArticleYear
[SIGNIFICANCE OF GENERAL ANESTHESIA IN NEUROSURGERY].
    Ideggyogyaszati szemle, 1964, Volume: 17

    Topics: Anesthesia; Anesthesia, Endotracheal; Anesthesia, General; Brain Neoplasms; Cerebral Angiography; Ce

1964
[THE RELATION BETWEEN THE CEREBROVASCULAR AND ELECTROGRAPHIC EFFECT OF HYPERCAPNIA UNDER THE INFLUENCE OF BARBITURATES].
    Helvetica physiologica et pharmacologica acta, 1964, Volume: 22

    Topics: Animals; Barbiturates; Brain; Carbon Dioxide; Cerebrovascular Circulation; Dogs; Electrophysiologica

1964
Free fatty acid accumulation in the pathogenesis and therapy of ischemic-anoxic brain injury.
    The American journal of emergency medicine, 1983, Volume: 1, Issue:2

    Topics: Animals; Brain Ischemia; Cinnarizine; Fatty Acids, Nonesterified; Flunarizine; Gallopamil; Hypoxia,

1983
Dose of thiopental, pentobarbital, and phenytoin for maximal therapeutic effects in cerebral ischemic anoxia.
    Critical care medicine, 1983, Volume: 11, Issue:6

    Topics: Animals; Brain Chemistry; Brain Ischemia; Fatty Acids, Nonesterified; Female; Hypoxia, Brain; Ketami

1983
[A method for the screening of anti-cerebral anoxia drugs].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1983, Volume: 18, Issue:1

    Topics: Adenosine Triphosphate; Animals; Drug Evaluation, Preclinical; Female; Hypoxia, Brain; Male; Pentoba

1983
Protective effect of flunarizine against cerebral hypoxia-anoxia in mice and rats.
    Journal of pharmacobio-dynamics, 1982, Volume: 5, Issue:4

    Topics: Animals; Cinnarizine; Flunarizine; Hypoxia, Brain; Male; Mice; Mice, Inbred Strains; Pentobarbital;

1982
Anoxic cerebral potassium accumulation reduced by phenytoin: mechanism of cerebral protection?
    Anesthesia and analgesia, 1981, Volume: 60, Issue:1

    Topics: Animals; Cisterna Magna; Dose-Response Relationship, Drug; Heart Arrest; Hypothermia, Induced; Hypox

1981
The interrelation between brain PO2 and NADH oxidation-reduction state in the gerbil.
    Journal of neuroscience research, 1980, Volume: 5, Issue:3

    Topics: Anesthesia, General; Animals; Brain Chemistry; Brain Ischemia; Chloral Hydrate; Cortical Spreading D

1980
Protective effect of R(-)-1-(benzo[b]thiophen-5-yl)- 2-[2-(N,N-diethylamino)ethoxy]ethanol hydrochloride (T-588), a novel cerebral activator, against experimental cerebral anoxia.
    Japanese journal of pharmacology, 1993, Volume: 62, Issue:1

    Topics: Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Diethylamines; Energy Metabolism;

1993
Prolonged exposure to hypobaric hypoxia transiently reduces GABA(A) receptor number in mice cerebral cortex.
    Brain research, 2001, Mar-09, Volume: 894, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Bicuculline; Cerebral Cortex; Desoxycorticosterone; GABA Antagonists;

2001
Intracellular redox states under halothane and barbiturate anesthesia in normal, ischemic, and anoxic monkey brain.
    Annals of neurology, 1979, Volume: 5, Issue:6

    Topics: Animals; Brain; Brain Ischemia; Carbon Dioxide; Cerebrovascular Circulation; Halothane; Haplorhini;

1979
Barbiturates in neurosurgery.
    Clinical neurosurgery, 1979, Volume: 26

    Topics: Animals; Barbiturates; Brain Ischemia; Cats; Cerebral Infarction; Dogs; Haplorhini; Humans; Hypoxia,

1979
Effect of ischemia and nembutal anesthesia on the activity of (Na+--K+)-ATPase and 5'-nucleatidase in the cellular membrane fraction from guinea pig brain.
    Bulletin de l'Academie polonaise des sciences. Serie des sciences biologiques, 1975, Volume: 23, Issue:9

    Topics: Adenosine Triphosphatases; Animals; Brain; Cell Membrane; Guinea Pigs; Hypoxia, Brain; Ischemic Atta

1975
Effect of various drugs on ischemic glial nuclei.
    Surgical forum, 1979, Volume: 30

    Topics: Acetazolamide; Animals; Brain; Brain Ischemia; Cell Nucleus; Dexamethasone; Female; Furosemide; Hypo

1979
Protective effect of a novel imidazole derivative against cerebral anoxia.
    Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 233, Issue:1

    Topics: Animals; Asphyxia; Atmospheric Pressure; Cyanides; Electroencephalography; Female; Hypoxia, Brain; I

1978
Effect of ischemic anoxia and barbiturate anesthesia on free radical oxidation of mitochondrial phospholipids.
    Brain research, 1978, Dec-15, Volume: 158, Issue:2

    Topics: Anesthesia, General; Animals; Barbiturates; Brain; Fatty Acids, Nonesterified; Free Radicals; Guinea

1978
Protective effect of minaprine against the abnormal changes of 2-deoxyglucose uptake by rat hippocampal slices induced by hypoxia/hypoglycemia.
    Japanese journal of pharmacology, 1992, Volume: 60, Issue:1

    Topics: Acetylcholine; Animals; Brain Ischemia; Central Nervous System Stimulants; Deoxyglucose; Hippocampus

1992
Variance of interburst intervals in burst suppression.
    Electroencephalography and clinical neurophysiology, 1991, Volume: 79, Issue:6

    Topics: Adolescent; Adult; Aged; Brain; Brain Ischemia; Child; Child, Preschool; Electroencephalography; Fem

1991
Synergistic interactions between piracetam and dihydroergocristine in some animal models of cerebral hypoxia and ischaemia.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:9

    Topics: Anesthesia; Animals; Avoidance Learning; Brain Ischemia; Cerebrovascular Circulation; Dihydroergotox

1986
Cultured neurons for testing cerebroprotective drug effects in vitro.
    Journal of pharmacological methods, 1988, Volume: 20, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Ch

1988
Narcolepsy following cerebral hypoxic ischemia.
    Annals of neurology, 1986, Volume: 19, Issue:5

    Topics: Anesthesia, Intravenous; Brain Ischemia; Cerebral Infarction; Humans; Hypoxia, Brain; Male; Middle A

1986
Barbiturate protection against hypoxic neuronal damage in vitro.
    Journal of neurosurgery, 1986, Volume: 65, Issue:2

    Topics: Animals; Female; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Neurons; Oxygen Consumption; Pent

1986
Brain metabolic correlates of hypoxic-ischemic cerebral necrosis in mid-gestational sheep fetuses: significance of hypotension.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1986, Volume: 6, Issue:4

    Topics: Animals; Blood Pressure; Brain; Brain Ischemia; Energy Metabolism; Female; Fetal Diseases; Hypotensi

1986
Changes in free fatty acids of brain by drug-induced convulsions, electroshock and anaesthesia.
    Journal of neurochemistry, 1971, Volume: 18, Issue:8

    Topics: Animals; Brain; Cell Membrane; Cyclic AMP; Electroshock; Ethyl Ethers; Fatty Acids, Nonesterified; H

1971
Differential effects of anesthetics on neutral proteinase activity of rat brain regions according to time of day.
    Brain research, 1972, Nov-13, Volume: 46

    Topics: Anesthetics; Animals; Brain; Carbon Dioxide; Caudate Nucleus; Cerebral Cortex; Ethyl Ethers; Hypotha

1972
Fetal and maternal electroencephalography in the guinea pig.
    Experimental neurology, 1966, Volume: 16, Issue:2

    Topics: Animals; Brain; Electroencephalography; Female; Fetus; Guinea Pigs; Hypoxia, Brain; Laparotomy; Mate

1966
Increased tolerance to cerebral anoxia by pentobarbital.
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 161, Issue:1

    Topics: Animals; Brain; Dogs; Hypoxia, Brain; Morphine; Oxygen; Pentobarbital; Procaine

1966