pentobarbital has been researched along with Altered Level of Consciousness in 4 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Two animal models of TLE--amygdala kindling and pilocarpine-induced status epilepticus (Pilo-SE)--were tested." | 3.75 | Pilocarpine model of temporal lobe epilepsy shows enhanced response to general anesthetics. ( Leung, LS; Long, JJ; Luo, T; McMurran, TJ; Shen, B; Stewart, L, 2009) |
| "A total of 61 patients were enrolled in the study (27 etomidate group, 34 pentobarbital group) at 2 different dosing regimens for etomidate." | 2.71 | Etomidate versus pentobarbital for sedation of children for head and neck CT imaging. ( Hunter, J; Kienstra, AJ; Macias, CG; Morriss, MC; Sasan, F; Ward, MA, 2004) |
| "Seizures were detected in 19% (n = 110) of patients who underwent cEEG monitoring; the seizures were exclusively nonconvulsive in 92% (n = 101) of these patients." | 2.42 | Detection of electrographic seizures with continuous EEG monitoring in critically ill patients. ( Claassen, J; Emerson, RG; Hirsch, LJ; Kowalski, RG; Mayer, SA, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Long, JJ | 1 |
| Shen, B | 1 |
| Luo, T | 1 |
| Stewart, L | 1 |
| McMurran, TJ | 1 |
| Leung, LS | 1 |
| Claassen, J | 1 |
| Mayer, SA | 1 |
| Kowalski, RG | 1 |
| Emerson, RG | 1 |
| Hirsch, LJ | 1 |
| Kienstra, AJ | 1 |
| Ward, MA | 1 |
| Sasan, F | 1 |
| Hunter, J | 1 |
| Morriss, MC | 1 |
| Macias, CG | 1 |
| Mushiroi, T | 1 |
| Shibahara, R | 1 |
| Tamura, M | 1 |
| Shimizu, T | 1 |
| Itoh, Y | 1 |
| Ukai, Y | 1 |
| Yoshikuni, Y | 1 |
| Kimura, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective Trial of Nonconvulsive Electrographic Seizure Detection by Nurses in the Adult Neuro ICU Using a Panel of Quantitative EEG Trends[NCT02082873] | 20 participants (Actual) | Observational | 2015-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pentobarbital and Altered Level of Consciousness
| Article | Year |
|---|---|
Detection of electrographic seizures with continuous EEG monitoring in critically ill patients.
Topics: Adult; Aged; Anticonvulsants; Brain Diseases; Child; Child, Preschool; Cohort Studies; Coma; Conscio | 2004 |
1 trial available for pentobarbital and Altered Level of Consciousness
| Article | Year |
|---|---|
Etomidate versus pentobarbital for sedation of children for head and neck CT imaging.
Topics: Child; Child, Preschool; Consciousness Disorders; Double-Blind Method; Emergency Service, Hospital; | 2004 |
2 other studies available for pentobarbital and Altered Level of Consciousness
| Article | Year |
|---|---|
Pilocarpine model of temporal lobe epilepsy shows enhanced response to general anesthetics.
Topics: Anesthetics, General; Animals; Brain; Consciousness Disorders; Convulsants; Disease Models, Animal; | 2009 |
[Montirelin hydrate (NS-3), a TRH analog, improved the disturbance of consciousness caused by head concussion and pentobarbital in mice].
Topics: Anesthesia; Animals; Brain Concussion; Consciousness Disorders; Male; Mice; Mice, Inbred Strains; Pe | 1996 |