pentobarbital has been researched along with Allodynia in 9 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diosgenin is a steroidal saponin extract from numerous plants, including Solanum and Dioscorea species, and has been reported to possess neuroprotective activity." | 1.46 | Diosgenin attenuates neuropathic pain in a rat model of chronic constriction injury. ( Song, HG; Sun, N; Wang, PF; Zhao, WX, 2017) |
| "To evaluate hyperalgesia, paw withdrawal latency (PWL) to radiant heat was measured before nerve constriction and five times after the constriction; just before TENS and at 1, 3, 7, and 14 days after the completion of TENS." | 1.32 | Long-lasting effect of transcutaneous electrical nerve stimulation on the thermal hyperalgesia in the rat model of peripheral neuropathy. ( Inoue, T; Mashimo, T; Nishimura, M; Sakaue, G; Shibata, M; Shibata, SC; Takenoshita, M, 2003) |
| "Nocifensive hyperreflexia was induced in 12 rats with 30 mg x kg(-1) pentobarbital ip." | 1.31 | Pentobarbital induces nocifensive yhyperreflexia, not hyperalgesia in rats. ( Archer, DP; Roth, SH; Samanani, N, 2000) |
| "This secondary hyperalgesia to thermal stimulation persisted for at least 1 h and was most likely mediated by central mechanisms." | 1.29 | Pentobarbital prevents the development of C-fiber-induced hyperalgesia in the rat. ( Cleland, CL; Foong-Yen, L; Gebhart, GF, 1994) |
| " Dose-response curves were monophasic and linear over this range." | 1.28 | Propofol and barbiturate depression of spinal nociceptive neurotransmission. ( Gibbs, LM; Jewett, BA; Kendig, JJ; Tarasiuk, A, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, WX | 1 |
| Wang, PF | 1 |
| Song, HG | 1 |
| Sun, N | 1 |
| Inoue, T | 1 |
| Takenoshita, M | 1 |
| Shibata, M | 1 |
| Nishimura, M | 1 |
| Sakaue, G | 1 |
| Shibata, SC | 1 |
| Mashimo, T | 1 |
| Cleland, CL | 1 |
| Foong-Yen, L | 1 |
| Gebhart, GF | 1 |
| Tarasiuk, A | 2 |
| Gibbs, L | 1 |
| Kendig, JJ | 2 |
| Tatsuo, MA | 1 |
| Yokoro, CM | 1 |
| Salgado, JV | 1 |
| Pesquero, SM | 1 |
| Santana, MA | 1 |
| Francischi, JN | 1 |
| Archer, DP | 1 |
| Samanani, N | 1 |
| Roth, SH | 1 |
| Pertovaara, A | 1 |
| Keski-Vakkuri, U | 1 |
| Kalmari, J | 1 |
| Wei, H | 1 |
| Panula, P | 1 |
| Jewett, BA | 1 |
| Gibbs, LM | 1 |
| Carmody, J | 1 |
| Jamieson, D | 1 |
| dePoortere, R | 1 |
9 other studies available for pentobarbital and Allodynia
| Article | Year |
|---|---|
Diosgenin attenuates neuropathic pain in a rat model of chronic constriction injury.
Topics: Animals; Constriction; Diosgenin; Disease Models, Animal; Hyperalgesia; Interleukin-12; Interleukin- | 2017 |
Long-lasting effect of transcutaneous electrical nerve stimulation on the thermal hyperalgesia in the rat model of peripheral neuropathy.
Topics: Anesthetics, Inhalation; Animals; Constriction; Disease Models, Animal; Halothane; Hot Temperature; | 2003 |
Pentobarbital prevents the development of C-fiber-induced hyperalgesia in the rat.
Topics: Anesthesia; Animals; Decerebrate State; Electric Stimulation; Hot Temperature; Hyperalgesia; Male; M | 1994 |
Descending inhibition in neonatal rat spinal cord: actions of pentobarbital and morphine.
Topics: Analgesics, Opioid; Animals; Animals, Newborn; Brain Stem; Denervation; Dose-Response Relationship, | 1996 |
Hyperalgesic effect induced by barbiturates, midazolam and ethanol: pharmacological evidence for GABA-A receptor involvement.
Topics: Animals; Barbiturates; Central Nervous System Depressants; Ethanol; GABA Antagonists; GABA Modulator | 1997 |
Pentobarbital induces nocifensive yhyperreflexia, not hyperalgesia in rats.
Topics: Animals; Behavior, Animal; Gene Expression; Genes, fos; Hot Temperature; Hyperalgesia; Hypnotics and | 2000 |
Response properties of neurons in the rostroventromedial medulla of neuropathic rats: attempted modulation of responses by [1DMe]NPYF, a neuropeptide FF analogue.
Topics: Action Potentials; Adjuvants, Anesthesia; Animals; Contrast Media; Hyperalgesia; Ligation; Male; Med | 2001 |
Propofol and barbiturate depression of spinal nociceptive neurotransmission.
Topics: Animals; Animals, Newborn; Depression, Chemical; Hyperalgesia; In Vitro Techniques; Pain; Pentobarbi | 1992 |
Opioid-independent hyperalgesia induced in mice by pentobarbitone at low dosage.
Topics: Animals; Hyperalgesia; Hyperesthesia; Male; Mice; Mice, Inbred BALB C; Pain Measurement; Pentobarbit | 1986 |