pentobarbital has been researched along with Alcohol Abuse in 20 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of oral pentobarbital on cigarette smoking and subjective response were determined in five adult men with histories of alcoholism and cigarette-smoking habits." | 5.05 | Cigarette smoking and subjective response in alcoholics: effects of pentobarbital. ( Chait, LD; Griffiths, RR; Henningfield, JE, 1983) |
| "Seizures and delirium tremens were recorded among 292 randomly selected patients admitted to an in-patient alcoholism program." | 1.27 | Should alcohol withdrawal seizures be treated with anti-epileptic drugs? ( Hillbom, ME; Hjelm-Jäger, M, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (85.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Besheer, J | 1 |
| Hodge, CW | 1 |
| Kozell, L | 1 |
| Belknap, JK | 2 |
| Hofstetter, JR | 1 |
| Mayeda, A | 1 |
| Buck, KJ | 2 |
| Hillbom, ME | 1 |
| Hjelm-Jäger, M | 1 |
| Henningfield, JE | 1 |
| Chait, LD | 1 |
| Griffiths, RR | 2 |
| Okamoto, M | 1 |
| Hinman, DJ | 1 |
| Aaronson, LM | 1 |
| Segel, LD | 2 |
| Rendig, SV | 1 |
| Haertzen, CA | 1 |
| Ross, FE | 1 |
| Crabbe, JC | 1 |
| Phillips, TJ | 1 |
| Cunningham, CL | 1 |
| Carlin, AS | 1 |
| Stauss, FF | 1 |
| Adams, KM | 1 |
| Grant, I | 1 |
| González Macías, J | 1 |
| De Castro del Pozo, S | 1 |
| Thompson, T | 1 |
| Pickens, R | 1 |
| Guarino, JJ | 1 |
| Roache, JD | 1 |
| Kirk, WT | 1 |
| Alpern, HP | 1 |
| McIntyre, TD | 1 |
| Kissin, B | 1 |
| Gross, MM | 1 |
| Zbinden, G | 1 |
| Randall, LO | 1 |
| Shah, MN | 1 |
| Clancy, BA | 1 |
| Iber, FL | 1 |
| Rubin, E | 2 |
| Bacchin, P | 1 |
| Gang, H | 1 |
| Lieber, CS | 2 |
| Daly, RJ | 1 |
| Kane, FJ | 1 |
3 reviews available for pentobarbital and Alcohol Abuse
| Article | Year |
|---|---|
Identifying genes for alcohol and drug sensitivity: recent progress and future directions.
Topics: Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Chromosome Mapping; Cocaine; Crosses, Genet | 1999 |
An experimental analysis of behavioral factors in drug dependence.
Topics: Administration, Oral; Alcoholism; Amphetamine; Animals; Behavior, Animal; Cannabis; Chlorpromazine; | 1975 |
Pharmacology of benzodiazepines: laboratory and clinical correlations.
Topics: Aggression; Alcoholism; Animals; Anticonvulsants; Anxiety; Autonomic Nervous System; Avoidance Learn | 1967 |
3 trials available for pentobarbital and Alcohol Abuse
| Article | Year |
|---|---|
Cigarette smoking and subjective response in alcoholics: effects of pentobarbital.
Topics: Adult; Alcoholism; Breath Tests; Drug Interactions; Ethanol; Humans; Male; Middle Aged; Pentobarbita | 1983 |
Comparison of the behavioral effects and abuse liability of ethanol and pentobarbital in recreational sedative abusers.
Topics: Adult; Affect; Alcohol Drinking; Alcoholism; Arousal; Dose-Response Relationship, Drug; Double-Blind | 1989 |
Evidence that the selectively bred long- and short-sleep mouse lines display common narcotic reactions to many depressants.
Topics: Alcoholism; Animals; Barbital; Barbiturates; Disease Susceptibility; Ethanol; Genetics, Behavioral; | 1985 |
14 other studies available for pentobarbital and Alcohol Abuse
| Article | Year |
|---|---|
Pharmacological and anatomical evidence for an interaction between mGluR5- and GABA(A) alpha1-containing receptors in the discriminative stimulus effects of ethanol.
Topics: Alcoholism; Animals; Diazepam; Discrimination, Psychological; Disease Models, Animal; Drug Interacti | 2005 |
Mapping a locus for alcohol physical dependence and associated withdrawal to a 1.1 Mb interval of mouse chromosome 1 syntenic with human chromosome 1q23.2-23.3.
Topics: Acute Disease; Alcohol Withdrawal Seizures; Alcoholism; Animals; Chromosome Mapping; Chromosomes, Ma | 2008 |
Should alcohol withdrawal seizures be treated with anti-epileptic drugs?
Topics: Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Anticonvulsants; Carbamazepine; Chlormethiazol | 1984 |
Comparison of ethanol and barbiturate physical dependence.
Topics: Alcoholism; Animals; Barbital; Barbiturates; Cats; Central Nervous System Depressants; Dose-Response | 1981 |
Dobutamine response of alcoholic rat hearts after cervical fracture or pentobarbital anesthesia.
Topics: Alcoholism; Anesthesia; Animals; Catecholamines; Cervical Vertebrae; Dobutamine; Fractures, Bone; He | 1982 |
Strength of drug habits: for heroin, morphine, methadone, alcohol, barbiturates, pentobarbital, benzedrine, cocaine, and marijuana.
Topics: Adult; Alcoholism; Amphetamines; Barbiturates; Cannabis; Cocaine; Heroin Dependence; Humans; Male; M | 1980 |
The prediction of neuropsychological impairment in polydrug abusers.
Topics: Adult; Alcoholism; Cannabis; Dextroamphetamine; Humans; Illicit Drugs; Life Style; Mental Disorders; | 1978 |
[Metabolism of phenylbutazone in the liver (author's transl)].
Topics: Alcoholism; Cholestasis; Diabetes Mellitus; Enzyme Induction; Epilepsy; Ethanol; Half-Life; Hepatiti | 1976 |
Tolerance to ethanol and cross-tolerance to pentobarbital by isolated hearts from chronic alcoholic rats.
Topics: Alcoholism; Animals; Drug Tolerance; Ethanol; Heart; In Vitro Techniques; Male; Pentobarbital; Perfu | 1988 |
Drug therapy in alcoholism.
Topics: Adult; Alcoholic Intoxication; Alcoholism; Antidepressive Agents; Anxiety; Carbamates; Chlordiazepox | 1970 |
Comparison of blood clearance of ethanol and tolbutamide and the activity of hepatic ethanol-oxidizing and drug-metabolizing enzymes in chronic alcoholic subjects.
Topics: Adult; Alcohol Oxidoreductases; Alcoholism; Aniline Compounds; Chronic Disease; Ethanol; Half-Life; | 1972 |
Induction and inhibition of hepatic microsomal and mitochondrial enzymes by ethanol.
Topics: Acyltransferases; Alcoholism; Aniline Compounds; Animals; Benzopyrenes; Centrifugation; Chemical and | 1970 |
Hepatic microsomal enzymes in man and rat: induction and inhibition by ethanol.
Topics: Alcoholism; Aniline Compounds; Animals; Barbiturates; Benzopyrenes; Depression, Chemical; Drug Toler | 1968 |
Two severe reactions to benzodiazepine compounds.
Topics: Adult; Alcoholism; Ataxia; Chlordiazepoxide; Diazepam; Drug Synergism; Humans; Male; Middle Aged; Mu | 1965 |