pentobarbital has been researched along with Aging in 65 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to determine the relative roles of viral-induced interferon (IFN) and viral infection of the liver in mouse cytomegalovirus (MCMV)-induced depression of cytochrome P-450 (cyt P-450) levels and enhancement of pentobarbital-induced sleeping time (PEN-ST)." | 7.67 | Increased susceptibility to pentobarbital following mouse cytomegalovirus infection: relative roles of viral-induced interferon and viral infection of the liver. ( Catignani, JC; Ménache, MG; Selgrade, MK, 1989) |
| "We recently showed that the glottis is actively closed throughout post-hyperventilation, hypocapnic central apnea in lambs." | 3.69 | Prolonged active glottic closure after barbiturate-induced respiratory arrest in lambs. ( Dalle, D; Diaz, V; Kianicka, I; Leroux, JF; Praud, JP, 1996) |
| "The purpose of this study was to determine the relative roles of viral-induced interferon (IFN) and viral infection of the liver in mouse cytomegalovirus (MCMV)-induced depression of cytochrome P-450 (cyt P-450) levels and enhancement of pentobarbital-induced sleeping time (PEN-ST)." | 3.67 | Increased susceptibility to pentobarbital following mouse cytomegalovirus infection: relative roles of viral-induced interferon and viral infection of the liver. ( Catignani, JC; Ménache, MG; Selgrade, MK, 1989) |
| "The effects of lead acetate and aging on temporally-spaced responding (differential reinforcement of low rate or DRL-20 seconds) were studied." | 3.66 | Effects of lead on temporally-spaced responding in rats. ( Dietz, DD; Grant, LD; Kimmel, CA; McMillan, DE, 1978) |
| "Pentobarbital-treated rats received i." | 1.31 | Evidence suggesting that the potentiating action of neuropeptide Y on luteinizing hormone (LH)-releasing hormone-induced LH release remains unaltered in aged female rats. ( Sahu, A, 2000) |
| " The response to a TRH challenge (10 micrograms/kg) was unaffected by the low dosage of SRIF14 infusion (0." | 1.28 | Somatostatin inhibition of thyrotropin-releasing hormone- and growth hormone-releasing factor-induced growth hormone secretion in young and adult anesthetized chickens. ( Harvey, S; Scanes, CG, 1989) |
| "The diazepam stimuli were dose-dependent in each group." | 1.27 | A comparison of diazepam stimuli in aged and adult rats. ( Amrick, CL; Bennett, DA, 1987) |
| " Increases in pharmacologic effect that occur with aging may be caused by alterations in pharmacokinetic parameters or changes at the site of drug action." | 1.27 | Pharmacodynamics and pharmacokinetics of ethanol, diazepam and pentobarbital in young and aged rats. ( Cooper, RL; Guthrie, S; Linnoila, M; Thurman, R, 1987) |
| "The pentobarbital sleeping time was significantly prolonged following the ozone exposure in both the mice and rats when compared with an air control." | 1.27 | Age-dependent inhibition of pentobarbital sleeping time by ozone in mice and rats. ( Calabrese, EJ; Canada, AT; Leonard, D, 1986) |
| "The 5-hydroxytryptophan-induced rise was prevented by the serotonergic antagonist cyproheptadine but not by the dopaminergic antagonist haloperidol." | 1.26 | Maturation of central nervous system control of growth hormone secretion in rats. ( Kuhn, CM; Schanberg, SM, 1981) |
| " In all cases, data on plasma levels were subjected to pharmacokinetic analyses." | 1.26 | Carbamazepine pharmacokinetics in young, adult and pregnant rats. Relation to pharmacological effects. ( Assael, BM; Bossi, L; Garattini, S; Gerna, M; Gomeni, R; Morselli, PL, 1976) |
| "6 Animals withdrawn following chronic administration of a number of drugs, barbitone, barbitone/bemegride mixture, Mandrax (methaqualone: diphenhydramine; 10: 1), chlordiazepoxide, nitrazepam, chlorpromazine or ethanol, exhibited a significant tolerance to intracerebroventricularly administered pentobarbitone." | 1.25 | A study of the factors affecting the sleeping time following intracerebroventricular administration of pentobarbitone sodium: effect of prior administration of centrally active drugs. ( Stevenson, IH; Turnbull, MJ, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (66.15) | 18.7374 |
| 1990's | 13 (20.00) | 18.2507 |
| 2000's | 7 (10.77) | 29.6817 |
| 2010's | 2 (3.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ota, Y | 1 |
| Ago, Y | 1 |
| Tanaka, T | 1 |
| Hasebe, S | 1 |
| Toratani, Y | 1 |
| Onaka, Y | 1 |
| Hashimoto, H | 1 |
| Takuma, K | 1 |
| Matsuda, T | 1 |
| Tong, LM | 1 |
| Yoon, SY | 1 |
| Andrews-Zwilling, Y | 1 |
| Yang, A | 1 |
| Lin, V | 1 |
| Lei, H | 1 |
| Huang, Y | 1 |
| Fu, Y | 1 |
| Guo, L | 1 |
| Zhang, J | 1 |
| Chen, Y | 1 |
| Wang, X | 1 |
| Zeng, T | 1 |
| Tian, S | 1 |
| Ma, Y | 1 |
| Yamazaki, H | 1 |
| Okazaki, M | 1 |
| Takeda, R | 1 |
| Haji, A | 1 |
| Vera, ER | 1 |
| Battell, ML | 1 |
| Bhanot, S | 1 |
| McNeill, JH | 1 |
| Ma, A | 1 |
| Guo, H | 1 |
| Chaudhary, V | 1 |
| Hansen, R | 1 |
| Lindgren, H | 1 |
| Fulton, A | 1 |
| DESBARATS-SCHONBAUM, ML | 1 |
| BIRMINGHAM, MK | 1 |
| JILEK, L | 3 |
| TROJAN, S | 3 |
| TRABUCCHI, E | 1 |
| CHIESARA, E | 2 |
| KATO, R | 2 |
| VASSANELLI, P | 1 |
| FRONTINO, G | 1 |
| Sato, T | 1 |
| Kuninaka, A | 1 |
| Yoshino, H | 1 |
| Ui, M | 1 |
| Saito, K | 1 |
| Goto, M | 1 |
| Fukuda, H | 1 |
| Sherman, MP | 1 |
| Lehrer, RI | 1 |
| Nass, TE | 1 |
| Terasawa, E | 1 |
| Dierschke, DJ | 1 |
| Goy, RW | 1 |
| Wise, PM | 1 |
| Ratner, A | 1 |
| Kuhn, CM | 1 |
| Schanberg, SM | 1 |
| Golda, V | 1 |
| Petr, R | 1 |
| Cermák, F | 1 |
| Malec, R | 1 |
| Ando, M | 1 |
| Kleeberg, U | 1 |
| Klinger, W | 1 |
| Lee, S | 1 |
| Panerai, AE | 1 |
| Bellabarba, D | 1 |
| Friesen, HG | 1 |
| Mayevsky, A | 1 |
| Shaya, B | 1 |
| Schwartz, JB | 1 |
| Shen, C | 1 |
| Garcia, J | 1 |
| Capili, H | 1 |
| Sniezek, M | 1 |
| Griffith, WH | 1 |
| Murchison, DA | 1 |
| Tsuchiya, T | 1 |
| Aguayo, LG | 1 |
| Alarcón, JM | 1 |
| Praud, JP | 1 |
| Kianicka, I | 1 |
| Diaz, V | 1 |
| Leroux, JF | 1 |
| Dalle, D | 1 |
| Alasmi, MM | 1 |
| Pickens, WL | 1 |
| Hoath, SB | 1 |
| Anzalone, CR | 1 |
| Lu, JK | 1 |
| LaPolt, PS | 2 |
| Sahu, A | 1 |
| Chern, BY | 1 |
| Chen, YH | 1 |
| Hong, LS | 1 |
| Blokland, A | 1 |
| Honig, W | 1 |
| Jolles, J | 1 |
| Bruguerolle, B | 1 |
| Mesdjian, E | 1 |
| Valli, M | 1 |
| Blanc, MC | 1 |
| Jadot, G | 1 |
| Bouyard, P | 1 |
| Glatt, AF | 1 |
| Talaat, HN | 1 |
| Koella, WP | 1 |
| Kohnen, R | 1 |
| Lienert, GA | 1 |
| Schmidt, FI | 1 |
| Messiha, FS | 1 |
| Osuide, G | 1 |
| Wambebe, C | 1 |
| Dietz, DD | 1 |
| McMillan, DE | 1 |
| Grant, LD | 1 |
| Kimmel, CA | 1 |
| Assael, BM | 1 |
| Bossi, L | 1 |
| Garattini, S | 1 |
| Gerna, M | 1 |
| Gomeni, R | 1 |
| Morselli, PL | 1 |
| Drake, WT | 1 |
| Creighan, M | 1 |
| Sims, DE | 1 |
| Otis, TS | 1 |
| Mody, I | 1 |
| Ruano, D | 1 |
| Cano, J | 1 |
| Machado, A | 1 |
| Vitorica, J | 1 |
| Backofen, JE | 1 |
| Koehler, RC | 1 |
| Harris, AP | 1 |
| Rogers, MC | 1 |
| Traystman, RJ | 1 |
| Jones, MD | 1 |
| Keir, WJ | 1 |
| Deitrich, RA | 1 |
| Concas, A | 1 |
| Pepitoni, S | 1 |
| Atsoggiu, T | 1 |
| Toffano, G | 1 |
| Biggio, G | 1 |
| Catignani, JC | 1 |
| Ménache, MG | 1 |
| Selgrade, MK | 1 |
| Scanes, CG | 1 |
| Harvey, S | 1 |
| Paramonova, GI | 1 |
| Sonntag, WE | 1 |
| Gough, MA | 1 |
| Meyers, MB | 1 |
| Komiskey, HL | 1 |
| Amrick, CL | 1 |
| Bennett, DA | 1 |
| Lee, JC | 1 |
| McGrath, CJ | 1 |
| Leighton, AT | 1 |
| Wilson, MH | 1 |
| Guthrie, S | 1 |
| Cooper, RL | 1 |
| Thurman, R | 1 |
| Linnoila, M | 1 |
| Canada, AT | 1 |
| Calabrese, EJ | 1 |
| Leonard, D | 1 |
| Stevenson, IH | 1 |
| Turnbull, MJ | 1 |
| Mellström, A | 1 |
| Effendi, H | 1 |
| Versprille, A | 1 |
| Wise, ME | 1 |
| Cairns, RB | 1 |
| Scholz, SD | 1 |
| Galatulas, I | 1 |
| Martini, M | 1 |
| Pomarelli, P | 1 |
| Piccinini, F | 1 |
| Fujii, T | 1 |
| Imai, M | 1 |
| Morohashi, C | 1 |
| Wakahara, E | 1 |
| Watanabe, M | 1 |
| Koyama, R | 1 |
| Takanaka, A | 1 |
| Randall, HM | 1 |
| Toth, LA | 1 |
| Kayahan, S | 1 |
| Aksu, Y | 1 |
65 other studies available for pentobarbital and Aging
| Article | Year |
|---|---|
Anxiolytic-like effects of restraint during the dark cycle in adolescent mice.
Topics: Aging; Animals; Anxiety; Brain; Conditioning, Psychological; Corticosterone; Darkness; Exploratory B | 2015 |
Enhancing GABA Signaling during Middle Adulthood Prevents Age-Dependent GABAergic Interneuron Decline and Learning and Memory Deficits in ApoE4 Mice.
Topics: Aging; Animals; Apolipoprotein E4; Female; GABA Agonists; gamma-Aminobutyric Acid; Gene Knock-In Tec | 2016 |
Differential effects of ageing on the EEG during pentobarbital and ketamine anaesthesia.
Topics: Adjuvants, Anesthesia; Aging; Anesthesia; Anesthetics, Dissociative; Animals; Electroencephalography | 2008 |
Hypercapnic and hypoxic ventilatory responses in long-term streptozotocin-diabetic rats during conscious and pentobarbital-induced anesthetic states.
Topics: Aging; Anesthetics; Animals; Blood Glucose; Body Weight; Consciousness; Diabetes Mellitus, Experimen | 2002 |
Effects of age and anesthetic on plasma glucose and insulin levels and insulin sensitivity in spontaneously hypertensive and Wistar rats.
Topics: Aging; Anesthetics; Animals; Area Under Curve; Blood Glucose; Glucose Tolerance Test; Insulin; Insul | 2002 |
[Effect of radix Achyranthis bidentatae on memory and endurance].
Topics: Achyranthes; Aging; Animals; Drugs, Chinese Herbal; Female; Male; Memory Disorders; Mice; Pentobarbi | 1998 |
Effects of telazol and nembutal on retinal responses.
Topics: Aging; Anesthetics, Dissociative; Animals; Animals, Newborn; Dark Adaptation; Drug Combinations; Ele | 2003 |
Effects of age and of Krebs-cycle metabolites on the inhibition of mouse brain respiration by pentobarbital.
Topics: Aging; Brain; Cell Respiration; Citric Acid Cycle; Humans; Pentobarbital; Respiration | 1959 |
[Influences on resistance of the body against oligemia and ischemia of the CNS during the course of ontogenesis].
Topics: Aging; Central Nervous System; Chlorpromazine; Hyperglycemia; Hypoxia; Ischemia; Pentobarbital | 1963 |
[Differences in influencing the course of anoxia and hypoxia of the central nervous system in ontogenesis].
Topics: Aging; Brain; Central Nervous System; Chlorpromazine; Humans; Hypoglycemia; Hypoxia; Pentobarbital | 1962 |
[VARIATIONS IN THE ENZYME ACTIVITY AND PHARMACOLOGIC EFFECTS IN RELATION TO AGE].
Topics: Aging; Aldosterone; Aspirin; Carisoprodol; Cholesterol; Cholinesterases; Dexamethasone; Meprobamate; | 1964 |
VARIATION IN THE ACTIVITY OF LIVER MICROSOMAL DRUG-METABOLIZING ENZYMES IN RATS IN RELATION TO THE AGE.
Topics: Aging; Animals, Newborn; Carisoprodol; Diphosphates; Hexobarbital; Insecticides; Liver; Meprobamate; | 1964 |
[The effect of chlorpromazine and pentobarbital on the survival of spinal reflexes and activity of the respiration center in rats after decapitation in the course of ontogenesis].
Topics: Aging; Animals; Chlorpromazine; Decapitation; Medulla Oblongata; Pentobarbital; Rats; Reflex; Respir | 1961 |
Plasma cyclic nucleotides in spontaneously hypertensive rats: hyperresponse to acute hot stress.
Topics: Aging; Animals; Autonomic Nervous System; Blood Pressure; Cyclic AMP; Cyclic GMP; Hot Temperature; H | 1984 |
Effects of pentobarbital on [3H]diazepam binding in the cerebral cortex, cerebellum and spinal cord of developing rats.
Topics: Aging; Animals; Anti-Anxiety Agents; Cerebellum; Cerebral Cortex; Diazepam; Female; In Vitro Techniq | 1984 |
Superoxide generation by neonatal and adult rabbit alveolar macrophages.
Topics: Aging; Animals; Animals, Newborn; Bordetella Infections; Cytochalasins; Female; Kinetics; Macrophage | 1984 |
Developmental changes in luteinizing hormone secretion in the female guinea pig. II. Positive feedback effects of ovarian steroids.
Topics: Aging; Animals; Estradiol; Feedback; Female; Guinea Pigs; Luteinizing Hormone; Pentobarbital; Proges | 1984 |
LHRH-induced LH and FSH responses in the aged female rat.
Topics: Aging; Animals; Diestrus; Estrus; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormo | 1980 |
Maturation of central nervous system control of growth hormone secretion in rats.
Topics: 5-Hydroxytryptophan; Aging; Animals; Central Nervous System; Clonidine; Female; Growth Hormone; Male | 1981 |
Blood pressure in the normotensive and genetically hypertensive rats: age, sex and narcosis dependency.
Topics: Aging; Animals; Blood Pressure; Female; Hypertension; Male; Pentobarbital; Rats; Rats, Inbred Strain | 1981 |
Cadmium effect on microsomal drug-metabolizing enzyme activity in rat livers with respect to differences in age and sex.
Topics: Aging; Animals; Cadmium; Cytochrome P-450 Enzyme System; Male; Microsomes, Liver; Mixed Function Oxy | 1982 |
Age course and inducibility of dimethylnitrosamine N-demethylation in rat liver.
Topics: Aging; Animals; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Enzyme | 1982 |
Effect of endocrine modifications and pharmacological treatments on brain and pituitary concentrations of beta-endorphin.
Topics: Adrenalectomy; Aging; Animals; Brain; Castration; Endorphins; Female; Male; Morphine; Naloxone; Pent | 1980 |
Factors affecting the development of hyperbaric oxygen toxicity in the awake rat brain.
Topics: Aging; Animals; Brain; Diazepam; Electroencephalography; Hyperbaric Oxygenation; Male; NAD; Pentobar | 1980 |
Influence of autonomic blockade and aging on AV conduction and responses to verapamil in the beagle.
Topics: Aging; Animals; Atrioventricular Node; Atropine; Autonomic Nervous System; Blood Pressure; Dogs; Dos | 1995 |
Enhancement of GABA-activated membrane currents in aged Fischer 344 rat basal forebrain neurons.
Topics: Action Potentials; Aging; Animals; Bicuculline; Drug Synergism; gamma-Aminobutyric Acid; Ion Channel | 1995 |
[Effects of cutaneous mechanical stimulation on plasma corticosterone, luteinizing hormone (LH), and testosterone levels in anesthetized male rats].
Topics: Aging; Anesthesia; Animals; Corticosterone; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Mal | 1994 |
Modulation of the developing rat sympathetic GABAA receptor by Zn++, benzodiazepines, barbiturates and ethanol.
Topics: Aging; Animals; Barbiturates; Benzodiazepines; Bicuculline; Diazepam; Ethanol; GABA-A Receptor Antag | 1993 |
Prolonged active glottic closure after barbiturate-induced respiratory arrest in lambs.
Topics: Abdominal Muscles; Aging; Animals; Animals, Newborn; Apnea; Electrodes, Implanted; Electromyography; | 1996 |
Effect of tactile stimulation on serum lactate in the newborn rat.
Topics: Aging; Animals; Animals, Newborn; Blood Glucose; Capsaicin; Carbon Dioxide; Epidermal Growth Factor; | 1997 |
Influences of age and reproductive status on ovarian ovulatory responsiveness to gonadotropin stimulation.
Topics: Aging; Animals; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Estrus; Female; Luteinizin | 1998 |
Evidence suggesting that the potentiating action of neuropeptide Y on luteinizing hormone (LH)-releasing hormone-induced LH release remains unaltered in aged female rats.
Topics: Aging; Animals; Drug Synergism; Estradiol; Female; Gonadotropin-Releasing Hormone; Luteinizing Hormo | 2000 |
Ovarian steroidogenic responsiveness to exogenous gonadotropin stimulation in young and middle-aged female rats.
Topics: Aging; Animals; Body Weight; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Dose-Re | 2000 |
Long-term consequences of repeated pentobarbital anaesthesia on choice reaction time performance in ageing rats.
Topics: Adjuvants, Anesthesia; Aging; Animals; Behavior, Animal; Drug Administration Schedule; Hypnotics and | 2001 |
[The effects of age and sex on the acute toxicity of two barbiturate anesthetics in rats].
Topics: Aging; Animals; Animals, Newborn; Female; Male; Pentobarbital; Rats; Sex Factors; Thiopental | 1977 |
Testing of peripheral nerve function in chronic experiments in rats.
Topics: Action Potentials; Aging; Animals; Electric Stimulation; Furazolidone; Male; Neural Conduction; Pent | 1979 |
[Clinico-physiological sleep- and hangover-spectra from pentobarbital, promazin and their combination, as reflected by self-ratings of young and elderly subjects (author's transl)].
Topics: Adult; Aged; Aging; Drug Combinations; Humans; Pentobarbital; Promazine; Sleep | 1979 |
Epididymal alcohol and aldehyde dehydrogenases in rodents.
Topics: Aging; Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Animals; Cricetinae; Disulfiram; Epididymi | 1979 |
Antagonism of pentobarbitone sleep by dopamine in young chicks [proceedings].
Topics: Aging; Animals; Chickens; Dopamine; Male; Pentobarbital; Sleep | 1977 |
Effects of lead on temporally-spaced responding in rats.
Topics: Aging; Animals; Animals, Newborn; Conditioning, Operant; Dextroamphetamine; Dose-Response Relationsh | 1978 |
Carbamazepine pharmacokinetics in young, adult and pregnant rats. Relation to pharmacological effects.
Topics: Aging; Animals; Carbamazepine; Electroshock; Female; Kinetics; Male; Maternal-Fetal Exchange; Pentob | 1976 |
Limitations of monastral blue as a vascular label: rapid rate of clearance is age-dependent, and interactions with anesthetics depress arterial blood pressure in rats.
Topics: Aging; Anesthetics; Animals; Blood Pressure; Coloring Agents; Drug Interactions; Halothane; Indoles; | 1992 |
Modulation of decay kinetics and frequency of GABAA receptor-mediated spontaneous inhibitory postsynaptic currents in hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Anesthetics, Local; Animal | 1992 |
Pharmacologic characterization of GABAA/benzodiazepine receptor in rat hippocampus during aging.
Topics: Aging; Animals; Binding Sites; Cerebellum; Cerebral Cortex; Culture Techniques; Drug Interactions; F | 1991 |
Efficacy of Cushing response during development in sheep.
Topics: Aging; Animals; Animals, Newborn; Blood Circulation; Blood Pressure; Brain; Cardiac Output; Cerebros | 1991 |
Development of central nervous system sensitivity to ethanol and pentobarbital in short- and long-sleep mice.
Topics: Aging; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Ethanol; Female; Gas Chromatograph | 1990 |
Aging reduces the GABA-dependent 36Cl- flux in rat brain membrane vesicles.
Topics: Aging; Animals; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocycl | 1988 |
Increased susceptibility to pentobarbital following mouse cytomegalovirus infection: relative roles of viral-induced interferon and viral infection of the liver.
Topics: Aging; Animals; Antibodies; Cytochrome P-450 Enzyme System; Cytomegalovirus; Cytomegalovirus Infecti | 1989 |
Somatostatin inhibition of thyrotropin-releasing hormone- and growth hormone-releasing factor-induced growth hormone secretion in young and adult anesthetized chickens.
Topics: Aging; Animals; Chickens; Dose-Response Relationship, Drug; Growth Hormone; Growth Hormone-Releasing | 1989 |
[The relationship of the intensity of liver microsomal oxidation to individual longevity].
Topics: Aging; Animals; Female; Longevity; Microsomes, Liver; Oxidation-Reduction; Pentobarbital; Rats; Rats | 1989 |
Growth hormone releasing hormone induced release of growth hormone in aging male rats: dependence on pharmacological manipulation and endogenous somatostatin release.
Topics: Aging; Animals; Ditiocarb; Growth Hormone; Growth Hormone-Releasing Hormone; Immunization, Passive; | 1988 |
Aging: effect on the interaction of ethanol and pentobarbital with the benzodiazepine-GABA receptor-ionophore complex.
Topics: Aging; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Ethanol; Flunitr | 1985 |
A comparison of diazepam stimuli in aged and adult rats.
Topics: Aging; Animals; Chlordiazepoxide; Diazepam; Discrimination Learning; Dose-Response Relationship, Dru | 1987 |
Effects of surgical pentobarbital anesthesia on blood pressure, heart rate, and arterial blood pH and gas tension in turkeys.
Topics: Acid-Base Equilibrium; Aging; Anesthesia, Intravenous; Animals; Blood Pressure; Body Weight; Carbon | 1988 |
Pharmacodynamics and pharmacokinetics of ethanol, diazepam and pentobarbital in young and aged rats.
Topics: Aging; Animals; Brain Chemistry; Diazepam; Ethanol; Female; Pentobarbital; Rats; Sleep | 1987 |
Age-dependent inhibition of pentobarbital sleeping time by ozone in mice and rats.
Topics: Aging; Animals; Cytochrome P-450 Enzyme System; Female; Liver; Mice; Mice, Inbred DBA; Ozone; Pentob | 1986 |
A study of the factors affecting the sleeping time following intracerebroventricular administration of pentobarbitone sodium: effect of prior administration of centrally active drugs.
Topics: Aging; Amphetamine; Animals; Anti-Anxiety Agents; Barbiturates; Body Weight; Carbon Radioisotopes; C | 1974 |
Postnatal excitability changes of the ankle monosynaptic reflexes in the cat.
Topics: Aging; Animals; Animals, Newborn; Ankle; Cats; Decerebrate State; Electric Stimulation; Laminectomy; | 1971 |
The negative inotropic effect of barbiturates on the heart of newborn and adult guinea-pigs.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Barbiturates; Depression, Chemical; Dose-Res | 1974 |
Fighting in mice: dyadic escalation and what is learned.
Topics: Aggression; Aging; Animals; Arousal; Behavior, Animal; Chlorpromazine; Dose-Response Relationship, D | 1973 |
Effect of drugs on the calcium exchangeability in the pineal gland.
Topics: Aging; Amphetamine; Animals; Biological Clocks; Calcium; Calcium Isotopes; Male; Pentobarbital; Pine | 1972 |
Sex and age differences in the effects of barbiturates.
Topics: Aging; Animals; Female; Male; Pentobarbital; Phenobarbital; Rats; Sex | 1965 |
Metabolism of drugs in old rats. II. Metabolism in vivo and effect of drugs in old rats.
Topics: Aging; Anesthesia; Animals; Carisoprodol; Female; Hexobarbital; Injections, Intraperitoneal; Insecti | 1968 |
Effects of spontaneous ischemia on aerobic metabolism of cortical and medullary homogenates of dog kidney.
Topics: Aging; Animals; Dogs; Female; Glutarates; Ischemia; Isocitrate Dehydrogenase; Kidney; Malate Dehydro | 1970 |
The effect of penthobarbital on stimulation threshold in young and old subjects.
Topics: Adolescent; Adult; Aged; Aging; Basal Metabolism; Female; Homeostasis; Humans; Male; Middle Aged; Ox | 1968 |