pentobarbital has been researched along with Age-Related Memory Disorders in 9 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, W | 2 |
| Tan, T | 2 |
| Yu, Y | 1 |
| Huang, Z | 1 |
| Du, Y | 1 |
| Han, H | 2 |
| Dong, Z | 2 |
| Tu, M | 1 |
| He, W | 1 |
| Tong, LM | 1 |
| Yoon, SY | 2 |
| Andrews-Zwilling, Y | 2 |
| Yang, A | 1 |
| Lin, V | 1 |
| Lei, H | 1 |
| Huang, Y | 2 |
| Bien-Ly, N | 1 |
| Xu, Q | 1 |
| Li, G | 1 |
| Bernardo, A | 1 |
| Zwilling, D | 1 |
| Yan, TX | 1 |
| Chen, L | 1 |
| Luo, J | 1 |
| Min, S | 1 |
| Wei, K | 1 |
| Li, P | 1 |
| Dong, J | 1 |
| Liu, YF | 1 |
| Ma, A | 1 |
| Guo, H | 1 |
| Wang, LW | 1 |
| Liu, XM | 1 |
| Lu, GH | 1 |
| Gao, NN | 1 |
| Xiao, PG | 1 |
| Kleen, JK | 1 |
| Sitomer, MT | 1 |
| Killeen, PR | 1 |
| Conrad, CD | 1 |
| Lineweaver, TT | 1 |
| Morris, HH | 1 |
| Naugle, RI | 1 |
| Najm, IM | 1 |
| Diehl, B | 1 |
| Bingaman, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Longitudinal Early-onset Alzheimer's Disease Study Protocol[NCT03507257] | 700 participants (Anticipated) | Observational | 2018-04-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for pentobarbital and Age-Related Memory Disorders
| Article | Year |
|---|---|
Inhibition of AMPAR endocytosis alleviates pentobarbital-induced spatial memory deficits and synaptic depression.
Topics: Animals; Depression; Endocytosis; Hippocampus; Long-Term Potentiation; Male; Memory Disorders; Memor | 2018 |
Acute pentobarbital treatment impairs spatial learning and memory and hippocampal long-term potentiation in rats.
Topics: Animals; Bicuculline; Biophysics; Dose-Response Relationship, Drug; Electric Stimulation; Escape Rea | 2015 |
Enhancing GABA Signaling during Middle Adulthood Prevents Age-Dependent GABAergic Interneuron Decline and Learning and Memory Deficits in ApoE4 Mice.
Topics: Aging; Animals; Apolipoprotein E4; Female; GABA Agonists; gamma-Aminobutyric Acid; Gene Knock-In Tec | 2016 |
Apolipoprotein E4 causes age- and Tau-dependent impairment of GABAergic interneurons, leading to learning and memory deficits in mice.
Topics: Age Factors; Analysis of Variance; Animals; Apolipoprotein E4; Cells, Cultured; Dentate Gyrus; Elect | 2010 |
Propofol protects against impairment of learning-memory and imbalance of hippocampal Glu/GABA induced by electroconvulsive shock in depressed rats.
Topics: Animals; Cognition; Depression; Down-Regulation; Electroconvulsive Therapy; Electroshock; gamma-Amin | 2011 |
[Effect of radix Achyranthis bidentatae on memory and endurance].
Topics: Achyranthes; Aging; Animals; Drugs, Chinese Herbal; Female; Male; Memory Disorders; Mice; Pentobarbi | 1998 |
[Primary research of pharmacological effects of PEC on mice].
Topics: Animals; Behavior, Animal; Drug Combinations; Drugs, Chinese Herbal; Epimedium; Fatigue; Hypoxia; Ma | 2004 |
Chronic stress impairs spatial memory and motivation for reward without disrupting motor ability and motivation to explore.
Topics: Adrenal Glands; Analysis of Variance; Animals; Behavior, Animal; Eating; Exploratory Behavior; Hippo | 2006 |
Evaluating the contributions of state-of-the-art assessment techniques to predicting memory outcome after unilateral anterior temporal lobectomy.
Topics: Anterior Temporal Lobectomy; Functional Laterality; Hippocampus; Humans; Magnetic Resonance Imaging; | 2006 |