pentobarbital has been researched along with Acute Disease in 29 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In order to study the effects of anesthetic agents on the inducibility of TdP, arrhythmias were induced by programmed electrical stimulation (PES) before and after cumulative intravenous administration of quinidine under anesthesia with sodium pentobarbital, halothane, or isoflurane." | 7.71 | Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole. ( Imai, R; Tamura, T; Yamamoto, K; Yamamoto, M, 2001) |
| "Controversy exists regarding the optimal means for monitoring the patient receiving pentobarbital therapy during medical coma." | 7.68 | Electroencephalographic activity and serum and cerebrospinal fluid pentobarbital levels in determining the therapeutic end point during barbiturate coma. ( Jimenez, F; Rosenwasser, RH; Winer, JW, 1991) |
| " PROSPECTIVE CONTROLLED CLINICAL TRIALS: Two of the 94 publications were prospective controlled studies (only one stated that allocation was via blinded randomisation), and both assessed the effect of multiple-dose activated charcoal for acute phenobarbital poisoning." | 4.87 | Enhanced elimination in acute barbiturate poisoning - a systematic review. ( Buckley, NA; Roberts, DM, 2011) |
| " In order to study the effects of anesthetic agents on the inducibility of TdP, arrhythmias were induced by programmed electrical stimulation (PES) before and after cumulative intravenous administration of quinidine under anesthesia with sodium pentobarbital, halothane, or isoflurane." | 3.71 | Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole. ( Imai, R; Tamura, T; Yamamoto, K; Yamamoto, M, 2001) |
| "Controversy exists regarding the optimal means for monitoring the patient receiving pentobarbital therapy during medical coma." | 3.68 | Electroencephalographic activity and serum and cerebrospinal fluid pentobarbital levels in determining the therapeutic end point during barbiturate coma. ( Jimenez, F; Rosenwasser, RH; Winer, JW, 1991) |
| "Assay of the clinical course of poisoning with acetic acid, dichloroethane, carbophos, chlorophos, phenobarbital and sodium etaminal in 2538 patients made it possible to define, with the use of the probit analysis, the 25, 50, 75 and 95% concentration thresholds of the lethality in acute poisonings with acetic acid, carbophos and dichloroethane." | 3.67 | [Age-related aspects of intensive therapy of acute poisoning of chemical etiology]. ( Dagaev, VN; Gorin, EE; Kostomarova, LG; Luzhnikov, EA, 1985) |
| " Dosing of the analgesics and sedatives was based on a neonatal sedation score for ventilated infants." | 1.32 | Endogenous distress in ventilated full-term newborns with acute respiratory failure. ( Aretz, S; Licht, C; Roth, B, 2004) |
| "Acute fetal hypoxemia was induced repeatedly by reducing uterine blood flow." | 1.29 | Effect of drugs on chemoreceptor responsiveness in fetal sheep. ( Baan, J; Boekkooi, PF; Rudolph, AM; Teitel, DF, 1995) |
| "Experimental vasogenic cerebral edema was created in rabbits with a cold-induced left occipital cortical lesions." | 1.26 | Acute therapeutic modalities for experimental vasogenic edema. ( Harbaugh, RD; James, HE; Laurin, R; Marshall, LF; Shapiro, HM, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (48.28) | 18.7374 |
| 1990's | 7 (24.14) | 18.2507 |
| 2000's | 5 (17.24) | 29.6817 |
| 2010's | 2 (6.90) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y | 1 |
| Lu, H | 1 |
| Xu, W | 1 |
| Shang, Y | 1 |
| Zhao, C | 1 |
| Wang, Y | 1 |
| Yang, R | 1 |
| Jin, S | 1 |
| Wu, Y | 1 |
| Wang, X | 1 |
| Teng, X | 1 |
| Wakai, A | 1 |
| McCabe, A | 1 |
| Roberts, I | 1 |
| Schierhout, G | 1 |
| Roberts, DM | 1 |
| Buckley, NA | 1 |
| Aretz, S | 1 |
| Licht, C | 1 |
| Roth, B | 1 |
| Koyama, K | 1 |
| Suzuki, R | 1 |
| Yoshida, T | 1 |
| Kikuno, T | 1 |
| Kozell, L | 1 |
| Belknap, JK | 1 |
| Hofstetter, JR | 1 |
| Mayeda, A | 1 |
| Buck, KJ | 1 |
| Lu, ZN | 2 |
| Cai, ZH | 2 |
| Wu, ZG | 2 |
| Traeger, SM | 1 |
| Henning, RJ | 1 |
| Dobkin, W | 1 |
| Giannotta, S | 1 |
| Weil, MH | 1 |
| Weiss, M | 1 |
| Benzi, G | 1 |
| Arrigoni, E | 1 |
| Pastoris, O | 1 |
| Villa, RF | 1 |
| Dossena, M | 1 |
| Agnoli, A | 1 |
| Giuffrida, AM | 1 |
| Sergienko, VI | 1 |
| Grigor'eva, AV | 1 |
| Artemkina, IV | 1 |
| Bul'chuk, OV | 1 |
| Lopukhin, IuM | 1 |
| Louis, PT | 1 |
| Goddard-Finegold, J | 1 |
| Fishman, MA | 1 |
| Griggs, JR | 1 |
| Stein, F | 1 |
| Laurent, JP | 1 |
| Boekkooi, PF | 1 |
| Baan, J | 1 |
| Teitel, DF | 1 |
| Rudolph, AM | 1 |
| Bironneau, E | 1 |
| Garrec, F | 1 |
| Kergueris, MF | 1 |
| Testa, A | 1 |
| Nicolas, F | 1 |
| Lam, AM | 1 |
| Coplin, WM | 1 |
| Matsumoto, Y | 1 |
| Tada, F | 1 |
| Sakata, S | 1 |
| Rodríguez Gil, DJ | 1 |
| Viapiano, MS | 1 |
| Fiszer de Plazas, S | 1 |
| Yamamoto, K | 1 |
| Tamura, T | 1 |
| Imai, R | 1 |
| Yamamoto, M | 1 |
| Juhl, B | 1 |
| Einer-Jensen, N | 1 |
| Harbaugh, RD | 1 |
| James, HE | 1 |
| Marshall, LF | 1 |
| Shapiro, HM | 1 |
| Laurin, R | 1 |
| Airaksinen, MM | 1 |
| Ho, BT | 1 |
| An, R | 1 |
| Taylor, D | 1 |
| Winer, JW | 1 |
| Rosenwasser, RH | 1 |
| Jimenez, F | 1 |
| Raneburger, J | 1 |
| Vermes, M | 1 |
| Eiselsberg, P | 1 |
| Hohenegger, M | 1 |
| Yan, J | 1 |
| Xu, RN | 1 |
| Dvorák, J | 1 |
| Trojan, S | 1 |
| St'astný, F | 1 |
| Luzhnikov, EA | 1 |
| Dagaev, VN | 1 |
| Kostomarova, LG | 1 |
| Gorin, EE | 1 |
| Greenway, CV | 1 |
| Stark, RD | 1 |
| Doroshchuk, VP | 1 |
| Popova, VN | 1 |
| Tsyganova, AM | 1 |
| Zingg, W | 1 |
3 reviews available for pentobarbital and Acute Disease
| Article | Year |
|---|---|
Mannitol for acute traumatic brain injury.
Topics: Acute Disease; Brain Injuries; Diuretics, Osmotic; Humans; Intracranial Hypertension; Intracranial P | 2013 |
Enhanced elimination in acute barbiturate poisoning - a systematic review.
Topics: Acute Disease; Adult; Barbiturates; Clinical Trials as Topic; Female; Humans; Pentobarbital; Phenoba | 2011 |
Hemodiafiltration in pentobarbital poisoning.
Topics: Acute Disease; Adult; Fatal Outcome; Hemodiafiltration; Humans; Hypnotics and Sedatives; Male; Pento | 1996 |
26 other studies available for pentobarbital and Acute Disease
| Article | Year |
|---|---|
Apelin ameliorated acute heart failure via inhibiting endoplasmic reticulum stress in rabbits.
Topics: Acute Disease; Animals; Apelin; Apelin Receptors; Disease Models, Animal; Endoplasmic Reticulum Stre | 2021 |
Endogenous distress in ventilated full-term newborns with acute respiratory failure.
Topics: Acute Disease; Analgesia; Female; Fentanyl; Humans; Hypnotics and Sedatives; Infant, Newborn; Intens | 2004 |
Usefulness of serum concentration measurement for acute pentobarbital intoxication in patients.
Topics: Acute Disease; Adult; Aged; Biomarkers; Female; Hemoperfusion; Humans; Male; Middle Aged; Pentobarbi | 2007 |
Mapping a locus for alcohol physical dependence and associated withdrawal to a 1.1 Mb interval of mouse chromosome 1 syntenic with human chromosome 1q23.2-23.3.
Topics: Acute Disease; Alcohol Withdrawal Seizures; Alcoholism; Animals; Chromosome Mapping; Chromosomes, Ma | 2008 |
[Resin hemoperfusion for acute pentobarbital intoxication in rats and rabbits].
Topics: Acute Disease; Animals; Charcoal; Female; Hemoperfusion; Male; Pentobarbital; Rabbits; Rats; Resins, | 1984 |
Hemodynamic effects of pentobarbital therapy for intracranial hypertension.
Topics: Acute Disease; Adolescent; Adult; Brain Injuries; Cerebrovascular Circulation; Hemodynamics; Humans; | 1983 |
Drug action on the metabolic changes induced by acute hypoxia on synaptosomes from the cerebral cortex.
Topics: Acute Disease; Animals; Cerebral Cortex; Choline; Cytidine Diphosphate Choline; Dogs; Female; Hypoxi | 1982 |
[The protective action of sodium hypochlorite on the morphology and transcription of the central neurons in rats with acute nembutal poisoning].
Topics: Acute Disease; Animals; Brain; Drug Evaluation, Preclinical; Male; Neurons; Pentobarbital; Poisoning | 1993 |
Barbiturates and hyperventilation during intracranial hypertension.
Topics: Acute Disease; Animals; Blood Flow Velocity; Blood Gas Analysis; Cerebrovascular Circulation; Combin | 1993 |
Effect of drugs on chemoreceptor responsiveness in fetal sheep.
Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Chemoreceptor Cells; Fetus; Heart Rate; Hypoxia | 1995 |
Pentobarbital and venous oxygenation.
Topics: Acute Disease; Brain Edema; Brain Injuries; Cerebral Veins; Coma; Humans; Oxygen; Pentobarbital | 1997 |
[Effects of pentobarbital on coronary and cerebral circulation and metabolism in dogs subjected to hemorrhage].
Topics: Acute Disease; Adjuvants, Anesthesia; Animals; Brain; Cerebrovascular Circulation; Coronary Circulat | 1999 |
Acute hypoxic hypoxia transiently reduces GABA(A) binding site number in developing chick optic lobe.
Topics: Acute Disease; Allosteric Regulation; Animals; Binding Sites; Chick Embryo; GABA Modulators; gamma-A | 2000 |
Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole.
Topics: Acute Disease; Anesthesia; Anesthetics, Inhalation; Animals; Astemizole; Atrioventricular Node; Cath | 2001 |
The effect of acute respiratory acidosis on the proportion: total splanchnic perfusion/cardiac output, and the alteration in this proportion by two anaesthetics.
Topics: Acidosis, Respiratory; Acute Disease; Anesthesia, Intravenous; Animals; Blood Pressure; Cardiac Outp | 1978 |
Acute therapeutic modalities for experimental vasogenic edema.
Topics: Acetazolamide; Acute Disease; Animals; Brain Edema; Cerebrovascular Disorders; Cold Temperature; Dex | 1979 |
Major pharmacological effects of 6-methoxytetrahydro-beta-carboline, a drug elevating the tissue 5-hydroxytryptamine level.
Topics: Acute Disease; Amphetamine; Animals; Blood Pressure; Body Temperature; Body Weight; Carbolines; Cats | 1978 |
Electroencephalographic activity and serum and cerebrospinal fluid pentobarbital levels in determining the therapeutic end point during barbiturate coma.
Topics: Acute Disease; Adolescent; Adult; Brain Injuries; Child; Coma; Electroencephalography; Female; Human | 1991 |
Reduced metabolic rate in acute uremic rats: interrelations between bilateral nephrectomy and anesthesia.
Topics: Acute Disease; Anesthesia; Animals; Male; Nephrectomy; Oxygen Consumption; Pentobarbital; Rats; Rats | 1989 |
Diacetylchitin coated resin hemoperfusion in dog acute pentobarbital intoxication.
Topics: Acute Disease; Animals; Chitin; Dogs; Female; Hemoperfusion; Male; Pentobarbital; Resins, Plant | 1986 |
[The effect of pentobarbital and pargyline on the development of acute experimental intracranial hypertension in chick embryos].
Topics: Acute Disease; Animals; Asphyxia; Brain Edema; Chick Embryo; Intracranial Pressure; Pargyline; Pento | 1987 |
[Age-related aspects of intensive therapy of acute poisoning of chemical etiology].
Topics: Acetates; Acetic Acid; Acute Disease; Adult; Age Factors; Critical Care; Ethylene Dichlorides; Hemop | 1985 |
The vascular responses of the spleen to intravenous infusions of catecholamines, angiotensin and vasopressi in the anaesthetized cat.
Topics: Acute Disease; Anesthesia, Intravenous; Angiotensin II; Animals; Catecholamines; Cats; Constriction; | 1970 |
[Principles of treatment of imminent respiratory disorders in acute poisoning with polychlorcamphen and polychlorpinen].
Topics: Acute Disease; Animals; Atropine; Cats; Chlorpromazine; Intubation; Pentobarbital; Pesticides; Rats; | 1974 |
[Neurologic manifestations of acute intermittent porphyria provoked by the use of barbiturates and estrogens (clinico-biochemical findings)].
Topics: Acute Disease; Adult; Female; Humans; Menstruation; Neurologic Manifestations; Pentobarbital; Porphy | 1971 |
Fast and slow rewarming after acute and prolonged hypothermia in rabbits.
Topics: Acute Disease; Anesthesia; Animals; Body Temperature; Chloralose; Chronic Disease; Heating; Hypnosis | 1969 |