pentobarbital has been researched along with Ache in 102 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effects of pentobarbital anesthesia on nociceptive processing in the medial and lateral pain pathways." | 7.76 | Effects of pentobarbital anesthesia on nociceptive processing in the medial and lateral pain pathways in rats. ( Gao, G; Luo, F; Wang, JY; Wang, N; Zhang, Y, 2010) |
| "Naloxone, per se, was ineffective." | 5.26 | Caerulein and morphine in a model of visceral pain. Effects on the hypotensive response to renal pelvis distension in the rat. ( Brasch, H; Zetler, G, 1982) |
| " In this study, we examined 3 commonly used euthanasia methods in mice: intraperitoneal injection of pentobarbital-phenytoin solution, CO2 inhalation, and isoflurane anesthesia followed by CO2 inhalation." | 3.85 | Physiologic, Behavioral, and Histologic Responses to Various Euthanasia Methods in C57BL/6NTac Male Mice. ( Boivin, GP; Bottomley, MA; Goss, L; Grobe, N; Schiml, PA, 2017) |
| "Formalin-induced acute inflammatory pain was established by intraplantar injection of 1% formalin without anesthesia or with anesthesia using the clinical anesthetics sevoflurane, propofol, or pentobarbital sodium." | 3.81 | Differential effects of general anesthetics on anxiety-like behavior in formalin-induced pain: involvement of ERK activation in the anterior cingulate cortex. ( Dai, RP; Li, CQ; Luo, C; Luo, W; Xu, JM; Zhang, YL; Zhou, FH, 2015) |
| "To investigate the effects of pentobarbital anesthesia on nociceptive processing in the medial and lateral pain pathways." | 3.76 | Effects of pentobarbital anesthesia on nociceptive processing in the medial and lateral pain pathways in rats. ( Gao, G; Luo, F; Wang, JY; Wang, N; Zhang, Y, 2010) |
| " The extract at given doses significantly and dose dependently reduced the frequency of acetic acid induced writhing in mice, prolonged the tail flicking latency in mice, reduced Carrageenan-induced paw edema volume in rat, delayed the onset as well as reduced the frequency of castor oil induced diarrhoeal episodes in mice, decreased gastrointestinal motility as assessed by the charcoal motility test in mice and prolonged pentobarbitone induced sleeping time in mice." | 3.73 | Preliminary pharmacological studies on Piper chaba stem bark. ( Ahmed, M; Faiz Hossain, C; Shilpi, JA; Taufiq-Ur-Rahman, M, 2005) |
| " In the first series of experiments, RT and VPL responses to pinching with a small artery clamp were tested with the rats under pentobarbital, urethane, ketamine, or halothane anesthesia." | 3.72 | Reticular thalamic responses to nociceptive inputs in anesthetized rats. ( Shaw, FZ; Yen, CT, 2003) |
| "Acetic acid-induced abdominal writhing, the tail flick test and carrageenan-induced peritonitis were used to study the analgesic and anti-inflammatory activity of the crude ethanolic extract from Spiranthera odoratissima roots." | 3.72 | Analgesic and anti-inflammatory activity of the ethanolic extract from Spiranthera odoratissima A. St. Hillaire (Manacá) roots. ( Costa, EA; Matos, LG; Paula, JR; Pontes, IS; Tresvenzol, LM, 2004) |
| " In NRGC neurons that responded to both nociception (tail clamp) and transient hypertension elicited by phenylephrine (5 micrograms/kg, i." | 3.69 | Interaction between neuronal responses to nociception and hypertension in the nucleus reticularis gigantocellularis of the rat. ( Chan, JY; Chan, SH; Kuo, TB; Tsai, HF, 1994) |
| " Few studies exist quantifying adverse events during and after euthanasia." | 2.61 | An Objective Exploration of Euthanasia and Adverse Events. ( Marchitelli, B, 2019) |
| "When ketamine was used as the general anesthetic, self-mutilation was almost suppressed (13%) and consisted of superficial erosions." | 1.32 | Effects of anesthesia and nociceptive stimulation in an experimental model of brachial plexus avulsion. ( Rokyta, R; Vaculín, S, 2004) |
| "Decreased pain was correlated with increased motor activity for morphine and amphetamine, and with decreased activity for xylazine and acepromazine; dipyrone and indomethacin did not alter activity levels." | 1.31 | The formalin test in the mouse: a parametric analysis of scoring properties. ( Abbott, FV; Saddi, GM, 2000) |
| " Dogs euthanatized with pentobarbital alone had significantly longer times than did dogs euthanatized with pentobarbital in combination with any of the lidocaine concentrations." | 1.29 | Comparison of pentobarbital alone and pentobarbital in combination with lidocaine for euthanasia of dogs. ( Broadstone, R; Evans, AT; Hooks, TM; Johnston, SM; McNeil, JR; Stapleton, J, 1993) |
| " Dose-response curves were monophasic and linear over this range." | 1.28 | Propofol and barbiturate depression of spinal nociceptive neurotransmission. ( Gibbs, LM; Jewett, BA; Kendig, JJ; Tarasiuk, A, 1992) |
| "Pretreatment with pentobarbital 250 micrograms prevented the facilitation by naloxone of C fibre-evoked activity." | 1.27 | Effects of intrathecally administered pentobarbital and naloxone on the activity evoked in ascending axons of the rat spinal cord by stimulation of afferent A and C fibres. Further evidence for a tonic endorphinergic inhibition in nociception. ( Bernatzky, G; Doi, T; Jurna, I, 1983) |
| " The elimination-phase half-life of pentobarbital was 8." | 1.27 | Pharmacokinetics of pentobarbital in the dog. ( Atkinson, AJ; Frederiksen, MC; Henthorn, TK; Ruo, TI, 1983) |
| "When pentobarbital and morphine were administered in combination by i." | 1.27 | Interaction of pentobarbital and morphine in the tail-flick test performed on rats: synergism at the spinal and antagonism at the supraspinal level. ( Carlsson, KH; Jurna, I, 1986) |
| "Naloxone, per se, was ineffective." | 1.26 | Caerulein and morphine in a model of visceral pain. Effects on the hypotensive response to renal pelvis distension in the rat. ( Brasch, H; Zetler, G, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 53 (51.96) | 18.7374 |
| 1990's | 18 (17.65) | 18.2507 |
| 2000's | 21 (20.59) | 29.6817 |
| 2010's | 7 (6.86) | 24.3611 |
| 2020's | 3 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, JA | 1 |
| Bopp, AC | 1 |
| Henwood, MK | 1 |
| Bean, P | 1 |
| Grau, JW | 2 |
| Laferriere, CA | 1 |
| Pang, DS | 1 |
| Reimer, JN | 1 |
| Schuster, CJ | 1 |
| Knight, CG | 1 |
| Pang, DSJ | 1 |
| Leung, VSY | 1 |
| Boivin, GP | 2 |
| Bottomley, MA | 1 |
| Schiml, PA | 1 |
| Goss, L | 1 |
| Grobe, N | 1 |
| Duckett, S | 1 |
| Dudley, ES | 1 |
| Marchitelli, B | 1 |
| Belmont, AP | 1 |
| Nossair, F | 1 |
| Brambilla, D | 1 |
| Friedman, M | 1 |
| Boswinkel, J | 1 |
| Bradford, AB | 1 |
| Kwiatkowski, JL | 1 |
| Luo, C | 1 |
| Zhang, YL | 1 |
| Luo, W | 1 |
| Zhou, FH | 1 |
| Li, CQ | 1 |
| Xu, JM | 1 |
| Dai, RP | 1 |
| Liu, L | 1 |
| Tsuruoka, M | 1 |
| Maeda, M | 1 |
| Hayashi, B | 1 |
| Wang, X | 1 |
| Inoue, T | 1 |
| Wang, N | 1 |
| Zhang, Y | 1 |
| Wang, JY | 1 |
| Gao, G | 1 |
| Luo, F | 1 |
| Wang, B | 1 |
| Samanani, N | 1 |
| Roth, SH | 2 |
| Archer, DP | 2 |
| Yen, CT | 2 |
| Shaw, FZ | 2 |
| Devi, KP | 1 |
| Sreepriya, M | 1 |
| Devaki, T | 1 |
| Balakrishna, K | 1 |
| COLLINS, W | 1 |
| HOLT, LB | 1 |
| ROBESON, K | 1 |
| ROYCE, PC | 1 |
| SAYERS, G | 1 |
| ALLEN, T | 1 |
| GRAFF, TD | 1 |
| PHILLIPS, OC | 1 |
| NELSON, AT | 1 |
| HARRIS, LC | 1 |
| FOX, ET | 1 |
| FRAZIER, TM | 1 |
| WEATHERALL, JA | 1 |
| CLIFFORD, DH | 1 |
| ARORA, RB | 1 |
| SHARMA, PL | 1 |
| ARGENT, DE | 1 |
| MITCHELL, CL | 2 |
| STRAW, RN | 1 |
| HILL, HE | 1 |
| BELLEVILLE, RE | 1 |
| WIKLER, A | 1 |
| Vaculín, S | 1 |
| Rokyta, R | 1 |
| Nishikawa, T | 1 |
| Takeda, M | 1 |
| Tanimoto, T | 1 |
| Matsumoto, S | 1 |
| Matos, LG | 1 |
| Pontes, IS | 1 |
| Tresvenzol, LM | 1 |
| Paula, JR | 1 |
| Costa, EA | 1 |
| Taufiq-Ur-Rahman, M | 1 |
| Shilpi, JA | 2 |
| Ahmed, M | 1 |
| Faiz Hossain, C | 1 |
| Gradl, G | 1 |
| Gaida, S | 1 |
| Finke, B | 1 |
| Lindenblatt, N | 1 |
| Gierer, P | 1 |
| Menger, MD | 1 |
| Mittlmeier, T | 1 |
| Vollmar, B | 1 |
| Craft, RM | 1 |
| Leitl, MD | 1 |
| Uddin, SJ | 1 |
| Rahman, MT | 1 |
| Ferdous, M | 1 |
| Rouf, R | 1 |
| Sarker, SD | 1 |
| Kumar, A | 1 |
| Kulkarni, SK | 1 |
| Kubota, I | 1 |
| Tsuboi, Y | 1 |
| Shoda, E | 1 |
| Kondo, M | 1 |
| Masuda, Y | 1 |
| Kitagawa, J | 1 |
| Oi, Y | 1 |
| Iwata, K | 1 |
| Washburn, SN | 1 |
| Patton, BC | 1 |
| Ferguson, AR | 1 |
| Hudson, KL | 1 |
| Svendsen, O | 1 |
| Kok, L | 1 |
| Lauritzen, B | 1 |
| Chen, YF | 1 |
| Li, N | 1 |
| Jiao, YL | 1 |
| Wei, P | 1 |
| Zhang, QY | 1 |
| Rahman, K | 1 |
| Zheng, HC | 1 |
| Qin, LP | 1 |
| Hori, Y | 1 |
| Lee, KH | 1 |
| Chung, JM | 1 |
| Endo, K | 1 |
| Willis, WD | 1 |
| Terman, GW | 1 |
| Shavit, Y | 1 |
| Lewis, JW | 1 |
| Cannon, JT | 1 |
| Liebeskind, JC | 2 |
| Kissin, I | 2 |
| Jebeles, JA | 1 |
| Bernatzky, G | 1 |
| Doi, T | 1 |
| Jurna, I | 2 |
| Frederiksen, MC | 1 |
| Henthorn, TK | 1 |
| Ruo, TI | 1 |
| Atkinson, AJ | 1 |
| Jensen, TS | 1 |
| Smith, DF | 1 |
| Moskovets, ON | 1 |
| Brasch, H | 1 |
| Zetler, G | 1 |
| Tomemori, N | 1 |
| Komatsu, T | 1 |
| Shingu, K | 1 |
| Urabe, N | 1 |
| Seo, N | 1 |
| Mori, K | 1 |
| Willow, M | 1 |
| Carmody, J | 1 |
| Carroll, P | 1 |
| Follett, KA | 1 |
| Dirks, B | 1 |
| Tsai, HF | 1 |
| Kuo, TB | 1 |
| Chan, JY | 1 |
| Chan, SH | 1 |
| Goto, T | 2 |
| Marota, JJ | 1 |
| Crosby, G | 1 |
| Evans, AT | 1 |
| Broadstone, R | 1 |
| Stapleton, J | 1 |
| Hooks, TM | 1 |
| Johnston, SM | 1 |
| McNeil, JR | 1 |
| McGaraughty, S | 1 |
| Reinis, S | 1 |
| Tsoukatos, J | 1 |
| Sapsed-Byrne, S | 1 |
| Holdcroft, A | 1 |
| Ridout, D | 1 |
| Abbott, FV | 2 |
| Guy, ER | 1 |
| Takahashi, H | 1 |
| Yanagida, H | 1 |
| Roychowdhury, SM | 1 |
| Heinricher, MM | 2 |
| Vatine, JJ | 1 |
| Ratner, A | 1 |
| Rosen, D | 1 |
| Seltzer, Z | 1 |
| Aikawa, N | 1 |
| Ohmori, K | 1 |
| Hiruma-Lima, CA | 1 |
| Gracioso, JS | 1 |
| Bighetti, EJ | 1 |
| Germonsén Robineou, L | 1 |
| Souza Brito, AR | 1 |
| Saddi, GM | 1 |
| Gurgel, LA | 1 |
| Santos, FA | 1 |
| Rao, VS | 1 |
| Rollin, BE | 1 |
| Chen, RF | 1 |
| Martin, BR | 1 |
| Dewey, WL | 1 |
| Chau-Pham, T | 1 |
| Prnage, AJ | 1 |
| Geller, EB | 1 |
| Durlofsky, L | 1 |
| Cowan, A | 1 |
| Harakal, C | 1 |
| Adler, MW | 1 |
| Passatore, M | 1 |
| Haigler, HJ | 1 |
| Emmers, R | 1 |
| Jewett, BA | 1 |
| Gibbs, LM | 1 |
| Tarasiuk, A | 1 |
| Kendig, JJ | 1 |
| Olivéras, JL | 1 |
| Montagne-Clavel, J | 1 |
| Martin, G | 1 |
| Iwasaki, H | 2 |
| Collins, JG | 3 |
| Namiki, A | 1 |
| Yamasawa, Y | 1 |
| Omote, K | 1 |
| Omote, T | 1 |
| Matsumoto, M | 1 |
| Haws, CM | 1 |
| Fields, HL | 1 |
| Ren, K | 1 |
| Saito, Y | 1 |
| Tang, J | 1 |
| Wang, QA | 1 |
| Mao, LM | 1 |
| Han, JS | 1 |
| Baumeister, AA | 1 |
| Hebert, G | 1 |
| Nagy, M | 1 |
| Hawkins, M | 1 |
| Maier, SF | 1 |
| Stein, C | 1 |
| Morgan, MM | 1 |
| Fleischmann, A | 1 |
| Urca, G | 1 |
| Wixson, SK | 1 |
| White, WJ | 1 |
| Hughes, HC | 1 |
| Marshall, WK | 1 |
| Lang, CM | 1 |
| Kajander, KC | 1 |
| Giesler, GJ | 1 |
| Pomeranz, B | 2 |
| Nguyen, P | 1 |
| Peets, JM | 1 |
| Dykstra, LA | 1 |
| Woods, JH | 1 |
| Carlsson, KH | 1 |
| Mason, JO | 1 |
| Vinik, HR | 1 |
| McDanal, J | 1 |
| Bradley, EL | 1 |
| Pendse, VK | 1 |
| Madan, BR | 1 |
| Krauthamer, GM | 1 |
| Whitaker, AH | 1 |
| Slater, P | 1 |
| Van Alstine, RS | 1 |
| Fisher, SJ | 1 |
| Moertel, CG | 1 |
| Ahmann, DL | 1 |
| Taylor, WF | 1 |
| Schwartau, N | 1 |
| Sherman, AD | 1 |
| Gebhart, GF | 1 |
| Ryhänen, P | 1 |
| Hollmén, A | 1 |
| Hinkula, A | 1 |
| Pakonen, ML | 1 |
| Pihlajaniemi, H | 1 |
| Kerkelä, A | 1 |
| Mima, T | 1 |
| Uchiyama, S | 1 |
| Onchi, Y | 1 |
| Lambelin, G | 1 |
| Roba, J | 1 |
| Gillet, C | 1 |
| Buu-Hoï, NP | 1 |
| Mizuguchi, T | 1 |
| Nakazato, K | 1 |
| Suzuki, H | 1 |
| Akita, H | 1 |
| Mietani, M | 1 |
| Jacobs, BL | 1 |
| Farel, PB | 1 |
| Koppel, AC | 1 |
| Adams-Koppel, E | 1 |
| Shanbhag, SM | 1 |
| Kulkarni, HJ | 1 |
| Gaitonde, BB | 1 |
| Hahn, L | 1 |
| Baldy-Moulinier, M | 1 |
| Ingvar, DH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Subanesthetic Sevoflurane for Treatment-Resistant Depression: A Proof-of-Concept Trial[NCT05008939] | 15 participants (Anticipated) | Interventional | 2021-08-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for pentobarbital and Ache
| Article | Year |
|---|---|
Review of Intraperitoneal Injection of Sodium Pentobarbital as a Method of Euthanasia in Laboratory Rodents.
Topics: Anesthetics, Inhalation; Animal Welfare; Animals; Animals, Laboratory; Biomedical Research; Euthanas | 2020 |
An Objective Exploration of Euthanasia and Adverse Events.
Topics: Animals; Euthanasia, Animal; Hypnotics and Sedatives; Pain; Pentobarbital | 2019 |
3 trials available for pentobarbital and Ache
| Article | Year |
|---|---|
Nociception after intraperitoneal injection of a sodium pentobarbitone formulation with and without lidocaine in rats quantified by expression of neuronal c-fos in the spinal cord--a preliminary study.
Topics: Anesthetics, Local; Animals; Hypnotics and Sedatives; Lidocaine; Male; Neurons; Pain; Pain Measureme | 2007 |
Relief of pain by oral medications. A controlled evaluation of analgesic combinations.
Topics: Administration, Oral; Analgesics; Aspirin; Azepines; Caffeine; Clinical Trials as Topic; Codeine; De | 1974 |
[Effects of sedatives on postoperative pain].
Topics: Blood Pressure; Chlorpromazine; Clinical Trials as Topic; Humans; Hypnotics and Sedatives; Injection | 1971 |
97 other studies available for pentobarbital and Ache
| Article | Year |
|---|---|
General Anesthesia Blocks Pain-Induced Hemorrhage and Locomotor Deficits After Spinal Cord Injury in Rats.
Topics: Anesthesia, General; Anesthetics; Animals; Contusions; Hemorrhage; Humans; Isoflurane; Pain; Pentoba | 2023 |
Intraperitoneal injection of sodium pentobarbital has the potential to elicit pain in adult rats (Rattus norvegicus).
Topics: Animals; Behavior, Animal; Female; Hypnotics and Sedatives; Injections, Intraperitoneal; Liver; Male | 2020 |
Physiologic, Behavioral, and Histologic Responses to Various Euthanasia Methods in C57BL/6NTac Male Mice.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Carbon Dioxide; Euthanasia, Animal; Hypnotics and Seda | 2017 |
Knowing, Anticipating, Even Facilitating but Still not Intending: Another Challenge to Double Effect Reasoning.
Topics: Advance Directives; Beneficence; Cause of Death; Decision Making; Ethics, Medical; Health Services A | 2018 |
Evaluation of a Commercially Available Euthanasia Solution as a Voluntarily Ingested Euthanasia Agent in Laboratory Mice.
Topics: Administration, Oral; Animals; Euthanasia, Animal; Female; Laboratory Animal Science; Male; Mice; Pa | 2018 |
Safety of deep sedation in young children with sickle cell disease: a retrospective cohort study.
Topics: Acute Chest Syndrome; Adjuvants, Anesthesia; Anemia, Sickle Cell; Child; Child, Preschool; Deep Seda | 2015 |
Differential effects of general anesthetics on anxiety-like behavior in formalin-induced pain: involvement of ERK activation in the anterior cingulate cortex.
Topics: Anesthetics, Inhalation; Animals; Anxiety; Behavior, Animal; Extracellular Signal-Regulated MAP Kina | 2015 |
Descending modulation of visceral nociceptive transmission from the locus coeruleus/subcoeruleus in the rat.
Topics: Animals; Colon; Electric Stimulation; Electrophysiology; Evoked Potentials; Hypnotics and Sedatives; | 2008 |
Effects of pentobarbital anesthesia on nociceptive processing in the medial and lateral pain pathways in rats.
Topics: Action Potentials; Anesthesia; Anesthetics; Animals; Brain; Gyrus Cinguli; Lasers; Male; Microelectr | 2010 |
Spinal carbonic anhydrase contributes to nociceptive reflex enhancement by midazolam, pentobarbital, and propofol.
Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Ethoxzolamide; Hypnotics | 2003 |
Reticular thalamic responses to nociceptive inputs in anesthetized rats.
Topics: Action Potentials; Afferent Pathways; Anesthesia; Anesthetics, Dissociative; Anesthetics, Inhalation | 2003 |
Antinociceptive and hypnotic effects of Premna tomentosa L. (Verbenaceae) in experimental animals.
Topics: Acetic Acid; Analgesics; Animals; Aspirin; Hypnotics and Sedatives; Male; Motor Activity; Pain; Pain | 2003 |
Tubocurarine and nembutal anesthesia.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Corneal Transplantation; Curare; Pain; Pentobarbita | 1958 |
Blood ACTH: effects of ether, pentobarbital, epinephrine and pain.
Topics: Adrenocorticotropic Hormone; Epinephrine; Ether; Ethers; Pain; Pentamidine; Pentobarbital | 1958 |
The intraperitoneal use of procaine hydrochloride with morphine-pentobarbital anesthesia.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Animals; Animals, Newborn; Morphine; Pain; Pain Man | 1959 |
Post-tonsillectomy analgesia: a double-blind study comparing pentobarbital, codeine and a placebo.
Topics: Analgesia; Codeine; Double-Blind Method; Humans; Pain; Pain Management; Pentobarbital; Placebos; Pos | 1961 |
Anaesthesia in new-born animals.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Animals; Animals, Newborn; Ethers; Pain; Pain Manag | 1960 |
Effect of preanesthetic medication with promazine and promethazine on pentobarbital anesthesia and subsequent hypothermia in the cat.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Animals; Cats; Hypothermia; Hypothermia, Induced; P | 1960 |
Mean auricularrate and ventricular response rate in auricular flutter in 200 dogs under sodium-pentobarbitone anaesthesia.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Animals; Atrial Flutter; Dogs; Pain; Pain Managemen | 1962 |
ANAESTHESIA AND ANALGESIA IN DOMICILIARY MIDWIFERY.
Topics: Analgesia; Anesthesia; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Inhalation; Anesthes | 1964 |
A COMPARISON OF DRUG EFFECTS UPON THE JAW JERK RESPONSE TO ELECTRICAL STIMULATION OF THE TOOTH PULP IN DOGS AND CATS.
Topics: Animals; Cats; Chlorpromazine; Dental Pulp; Dogs; Electric Stimulation; Morphine; Pain; Pentobarbita | 1964 |
THE EFFECTS OF MORPHINE, PENTOBARBITAL, PENTAZOCINE AND NALORPHINE ON BIOELECTRICAL POTENTIALS EVOKED IN THE BRAIN STEM OF THE CAT BY ELECTRICAL STIMULATION OF THE TOOTH PULP.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Brain; Brain Stem; Cats; Dental Pulp; Electric S | 1964 |
Studies on anxiety associated with anticipation of pain. II. Comparative effects of pentobarbital and morphine.
Topics: Anxiety; Barbiturates; Humans; Morphine; Pain; Pentobarbital | 1955 |
Effects of anesthesia and nociceptive stimulation in an experimental model of brachial plexus avulsion.
Topics: Anesthesia; Animals; Brachial Plexus; Ketamine; Male; Models, Animal; Nociceptors; Pain; Pentobarbit | 2004 |
Convergence of nociceptive information from temporomandibular joint and tooth pulp afferents on C1 spinal neurons in the rat.
Topics: Animals; Dental Pulp; Electric Stimulation; Electromyography; Histological Techniques; Male; Neurons | 2004 |
Analgesic and anti-inflammatory activity of the ethanolic extract from Spiranthera odoratissima A. St. Hillaire (Manacá) roots.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cell Migrati | 2004 |
Preliminary pharmacological studies on Piper chaba stem bark.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidiarrheals; Carrageenan; Central | 2005 |
Supernatant of traumatized muscle induces inflammation and pain, but not microcirculatory perfusion failure and apoptotic cell death.
Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Death; Edema; Hemodynamics; In Situ | 2005 |
Potentiation of morphine antinociception by pentobarbital in female vs. male rats.
Topics: Adjuvants, Anesthesia; Analgesics, Opioid; Analysis of Variance; Animals; Castration; Disease Models | 2006 |
Assessment of neuropharmacological activities of Pandanus foetidus (Pandanaceae) in mice.
Topics: Acetic Acid; Analgesics; Animals; Dose-Response Relationship, Drug; Female; Hypnotics and Sedatives; | 2006 |
Protective effect of BR-16A, a polyherbal preparation against social isolation stress: possible GABAergic mechanism.
Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Female; Flumazenil; GABA Ago | 2006 |
Modulation of neuronal activity in CNS pain pathways following propofol administration in rats: Fos and EEG analysis.
Topics: Anesthesia; Anesthetics, Intravenous; Anesthetics, Local; Animals; Central Nervous System; Conscious | 2007 |
Exposure to intermittent nociceptive stimulation under pentobarbital anesthesia disrupts spinal cord function in rats.
Topics: Animals; Behavior, Animal; Conditioning, Operant; Electroshock; Hindlimb; Hypnotics and Sedatives; M | 2007 |
Antinociceptive activity of petroleum ether fraction from the MeOH extracts of Paederia scandens in mice.
Topics: Acetic Acid; Alkanes; Analgesics; Animals; Capsaicin; Formaldehyde; Hot Temperature; Methanol; Mice; | 2008 |
The effects of small doses of barbiturate on the activity of primate nociceptive tract cells.
Topics: Anesthesia, General; Animals; Cerebral Decortication; Decerebrate State; Halothane; Nerve Fibers; Ni | 1984 |
Intrinsic mechanisms of pain inhibition: activation by stress.
Topics: Adaptation, Physiological; Adrenalectomy; Anesthesia; Animals; Brain Stem; Conditioning, Psychologic | 1984 |
Halothane antagonizes effect of morphine on the motor reaction threshold in rats.
Topics: Animals; Constriction; Dose-Response Relationship, Drug; Halothane; Morphine; Motor Activity; Pain; | 1984 |
Effects of intrathecally administered pentobarbital and naloxone on the activity evoked in ascending axons of the rat spinal cord by stimulation of afferent A and C fibres. Further evidence for a tonic endorphinergic inhibition in nociception.
Topics: Afferent Pathways; Animals; Axons; Electric Stimulation; Endorphins; Evoked Potentials; Female; Inje | 1983 |
Pharmacokinetics of pentobarbital in the dog.
Topics: Anesthesia, Intravenous; Animals; Blood Volume; Dogs; Female; Hematocrit; Kinetics; Male; Pain; Pent | 1983 |
Stimulation of spinal dopaminergic receptors: differential effects on tail reflexes in rats.
Topics: Animals; Apomorphine; Dopamine; Male; Pain; Pentobarbital; Rats; Rats, Inbred Strains; Reaction Time | 1983 |
[Effect of auricular electroacupuncture on the motor manifestations of nociceptive reactions].
Topics: Acupuncture Therapy; Animals; Cats; Ear, External; Electric Stimulation Therapy; Electromyography; M | 1980 |
Caerulein and morphine in a model of visceral pain. Effects on the hypotensive response to renal pelvis distension in the rat.
Topics: Animals; Blood Pressure; Ceruletide; Disease Models, Animal; Kidney Pelvis; Male; Morphine; Naloxone | 1982 |
Activation of the supraspinal pain inhibition system by ketamine hydrochloride.
Topics: Animals; Bradykinin; Cats; Decerebrate State; Female; Ketamine; Male; Pain; Pentobarbital; Spinal Co | 1981 |
The effects of swimming in mice on pain perception and sleeping time in response to hypnotic drugs.
Topics: Animals; Ethanol; Female; Mice; Morphine; Naloxone; Pain; Pentobarbital; Sleep; Stress, Physiologica | 1980 |
Responses of neurons in ventrolateral orbital cortex to noxious visceral stimulation in the rat.
Topics: Animals; Cerebral Cortex; Electric Stimulation; Male; Nerve Fibers; Neurons; Nociceptors; Pain; Pent | 1995 |
Interaction between neuronal responses to nociception and hypertension in the nucleus reticularis gigantocellularis of the rat.
Topics: Anesthesia; Animals; Basal Ganglia; Blood Pressure; Evoked Potentials; Hypertension; Male; Neurons; | 1994 |
Pentobarbitone, but not propofol, produces pre-emptive analgesia in the rat formalin model.
Topics: Analgesics; Anesthesia, Intravenous; Animals; Behavior, Animal; Disease Models, Animal; Formaldehyde | 1994 |
Comparison of pentobarbital alone and pentobarbital in combination with lidocaine for euthanasia of dogs.
Topics: Animals; Dogs; Drug Combinations; Drug Synergism; Electrocardiography; Euthanasia; Female; Injection | 1993 |
A correlogram analysis of the activity in the rostral ventromedial medulla of awake rats and in rats anesthetized with ketamine or pentobarbital following the administration of morphine.
Topics: Action Potentials; Analgesics, Opioid; Animals; Data Interpretation, Statistical; Drug Combinations; | 1995 |
The influence of colonic temperature changes in anaesthetised rats on tail skin temperatures and repeated testing of tail-flick latencies.
Topics: Analysis of Variance; Anesthesia; Animals; Behavior, Animal; Body Temperature; Colon; Female; Pain; | 1995 |
Effects of morphine, pentobarbital and amphetamine on formalin-induced behaviours in infant rats: sedation versus specific suppression of pain.
Topics: Amphetamine; Animals; Animals, Newborn; Behavior, Animal; Female; Formaldehyde; Hypnotics and Sedati | 1995 |
Is pentobarbital analgesic in the rat formalin test?
Topics: Animals; Dose-Response Relationship, Drug; Formaldehyde; Hypnotics and Sedatives; Pain; Pentobarbita | 1997 |
Effects of iontophoretically applied serotonin on three classes of physiologically characterized putative pain modulating neurons in the rostral ventromedial medulla of lightly anesthetized rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia, General; Animals; Evoked Potentials; Iontophores | 1997 |
Differential sensory-motor effects of pentobarbital in intact rats genetically selected for high vs. low neuropathic pain-related behaviour.
Topics: Animals; Behavior, Animal; Male; Motor Activity; Pain; Pain Measurement; Pentobarbital; Rats; Rats, | 1998 |
Acetazolamide and amiloride inhibit pentobarbital-induced facilitation of nocifensive reflexes.
Topics: Acetazolamide; Amiloride; Animals; GABA Modulators; Male; NG-Nitroarginine Methyl Ester; Pain; Pento | 1999 |
Effect of zaldaride maleate, an antidiarrheal compound, on visceral pain reflex induced by small intestinal distention in anesthetized rats.
Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Animals, Newborn; Antidiarrheals; Atropine; Benzi | 1999 |
The juice of fresh leaves of Boerhaavia diffusa L. (Nyctaginaceae) markedly reduces pain in mice.
Topics: Acetates; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Carrageenan; Edema; Hot Temperature | 2000 |
The formalin test in the mouse: a parametric analysis of scoring properties.
Topics: Acepromazine; Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Amphetamine; Analgesics, Opioid; Ani | 2000 |
Effects of human placental extract on chemical and thermal nociception in mice.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Hot Temperature; | 2000 |
An ethicist's commentary on the producer who is unwilling to euthanize sick pigs.
Topics: Animal Husbandry; Animals; Ethics, Professional; Euthanasia; Pain; Pentobarbital; Swine; Swine Disea | 2001 |
Dynamic changes of touch- and laser heat-evoked field potentials of primary somatosensory cortex in awake and pentobarbital-anesthetized rats.
Topics: Adjuvants, Anesthesia; Animals; Behavior, Animal; Electroencephalography; Evoked Potentials, Somatos | 2001 |
Interactions of thyrotropin releasing hormone and morphine sulfate in rodents.
Topics: Analgesics; Animals; Apomorphine; Behavior, Animal; Body Weight; Chlorpromazine; Dronabinol; Humans; | 1977 |
The effect of pentobarbital on the antinociceptive action of morphine in morphine-tolerant and non-tolerant rats.
Topics: Animals; Drug Tolerance; Humans; Male; Morphine; Morphine Dependence; Pain; Pentobarbital; Rats; Sen | 1979 |
Physiological characterization of efferent cervical sympathetic fibers influenced by changes of illumination.
Topics: Animals; Asphyxia; Blood Pressure; Body Temperature; Cats; Cervical Plexus; Evoked Potentials; Light | 1976 |
Morphine: ability to block neuronal activity evoked by a nociceptive stimulus.
Topics: Action Potentials; Animals; Brain Stem; Chlorpromazine; Levorphanol; Male; Methadone; Morphine; Nalo | 1976 |
Thalamic mechanisms that process a temporal pulse code for pain.
Topics: Action Potentials; Animals; Electric Stimulation; Electrocoagulation; Morphine; Nerve Degeneration; | 1976 |
Propofol and barbiturate depression of spinal nociceptive neurotransmission.
Topics: Animals; Animals, Newborn; Depression, Chemical; Hyperalgesia; In Vitro Techniques; Pain; Pentobarbi | 1992 |
Drastic changes of ventromedial medulla neuronal properties induced by barbiturate anesthesia. I. Comparison of the single-unit types in the same awake and pentobarbital-treated rats.
Topics: Anesthesia; Animals; Electric Stimulation; Electroencephalography; Hot Temperature; Medulla Oblongat | 1991 |
[Comparison of the effect of propofol and that of pentobarbital on behavioral responses to somatic and visceral stimuli in rats].
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Male; Pain; Pentobarbital; Propofol; Ra | 1991 |
Alpha-adrenergic receptor agonists, but not antagonists, alter the tail-flick latency when microinjected into the rostral ventromedial medulla of the lightly anesthetized rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Male; Medulla Oblongata; Microinje | 1990 |
Plasticity of some spinal dorsal horn neurons as revealed by pentobarbital-induced disinhibition.
Topics: Animals; Cats; Female; Hot Temperature; Neuronal Plasticity; Neurons; Pain; Pentobarbital; Physical | 1990 |
Analgesia from electrical stimulation of the hypothalamic arcuate nucleus in pentobarbital-anesthetized rats.
Topics: Analgesia; Animals; Arcuate Nucleus of Hypothalamus; Brain Mapping; Electric Stimulation; Female; Na | 1990 |
Pentobarbital attenuates the antinociceptive effect of intranigral morphine.
Topics: Animals; Drug Interactions; Male; Morphine; Pain; Pentobarbital; Rats; Rats, Inbred Strains; Referen | 1989 |
Determinants of the nature of environmentally induced hypoalgesia.
Topics: Analgesia; Animals; Electroshock; Endorphins; Male; Naltrexone; Pain; Pentobarbital; Rats; Rats, Inb | 1989 |
Barbiturate-induced inhibition of a spinal nociceptive reflex: role of GABA mechanisms and descending modulation.
Topics: Analgesics; Animals; Depression, Chemical; gamma-Aminobutyric Acid; Male; Pain; Pentobarbital; Rats; | 1987 |
Different endogenous analgesia systems are activated by noxious stimulation of different body regions.
Topics: Analgesia; Animals; Brain; Male; Mice; Mice, Inbred ICR; Nociceptors; Organ Specificity; Pain; Pento | 1988 |
The effects of pentobarbital, fentanyl-droperidol, ketamine-xylazine and ketamine-diazepam on noxious stimulus perception in adult male rats.
Topics: Anesthesia; Anesthetics; Animals; Diazepam; Droperidol; Drug Combinations; Fentanyl; Ketamine; Male; | 1987 |
Responses of neurons in the lateral cervical nucleus of the cat to noxious cutaneous stimulation.
Topics: Animals; Cats; Decerebrate State; Evoked Potentials, Somatosensory; Methohexital; Nociceptors; Pain; | 1987 |
Intrathecal diazepam suppresses nociceptive reflexes and potentiates electroacupuncture effects in pentobarbital-anesthetized rats.
Topics: Acupuncture Therapy; Anesthesia, Intravenous; Animals; Diazepam; Drug Synergism; Humans; Injections, | 1987 |
A descriptive study of spinal dorsal horn neurons in the physiologically intact, awake, drug-free cat.
Topics: Action Potentials; Anesthesia; Animals; Cats; Female; Male; Membrane Potentials; Neurons, Afferent; | 1987 |
Studies in suppression of nocifensive reflexes measured with tail flick electromyograms and using intrathecal drugs in barbiturate anesthetized rats.
Topics: Anesthesia; Animals; Conditioning, Classical; Electric Stimulation; Electromyography; Injections, Sp | 1987 |
A tail withdrawal procedure for assessing analgesic activity in rhesus monkeys.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Female; Haloperidol; Hot Temperature; Male; M | 1986 |
Interaction of pentobarbital and morphine in the tail-flick test performed on rats: synergism at the spinal and antagonism at the supraspinal level.
Topics: Animals; Central Nervous System; Drug Interactions; Female; Injections, Intraperitoneal; Injections, | 1986 |
Barbiturates inhibit stress-induced analgesia.
Topics: Animals; Male; Naloxone; Pain; Pain Measurement; Pentobarbital; Rats; Rats, Inbred Strains; Sensory | 1987 |
Some pharmacological actions of cyclizine, chlorcyclizine and homchlorcyclizine.
Topics: Acetylcholine; Animals; Anura; Central Nervous System; Conditioning, Psychological; Cyclizine; Diaph | 1969 |
Cortical synchronization evoked by noxious bradykinin stimulation under barbiturate anesthesia.
Topics: Anesthesia, Intravenous; Animals; Bradykinin; Cats; Cerebral Cortex; Cortical Synchronization; Elect | 1974 |
Effect of 6-hydroxydopamine on some actions of tremorine and oxotremorine.
Topics: Amines; Animals; Body Temperature; Brain Chemistry; Catecholamines; Dopamine; Dose-Response Relation | 1974 |
Use of sedation-analgesia in general dentistry.
Topics: Analgesia; Anesthesia, Dental; Diazepam; Humans; Meperidine; Nitrous Oxide; Pain; Pentobarbital; Sco | 1973 |
Pain-induced alteration of glutamate in periaqueductal central gray and its reversal by morphine.
Topics: Animals; Chlorpromazine; Glutamates; Hypothalamus; Male; Mice; Morphine; Naloxone; Nociceptors; Pain | 1974 |
Patient's views on general anaesthesia.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Inhalation; Attitude; Cognition; Diazepam; | 1973 |
Pharmacology of a new analgesic, antipyretic, and anti-inflammatory agent, 4-allyloxy-3-chlorophenylacetic acid.
Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Carrageenan; Codeine | 1970 |
[Effect of sedatives on pain threshold].
Topics: Adult; Diazepam; Female; Humans; Hypnotics and Sedatives; Meperidine; Pain; Pentazocine; Pentobarbit | 1971 |
Motivated behaviors produced by increased arousal in the presence of goal objects.
Topics: Aggression; Animal Nutritional Physiological Phenomena; Animals; Arousal; Behavior, Animal; Consumma | 1971 |
A method of intravenous medication.
Topics: Anxiety; Humans; Injections, Intravenous; Meperidine; Pain; Pentobarbital; Preanesthetic Medication; | 1969 |
Pharmacological actions of berberine on the central nervous system.
Topics: Alkaloids; Amphetamine; Analgesics; Animals; Anticonvulsants; Cats; Central Nervous System; Drug Syn | 1970 |
Continuous paracervical block anaesthesia.
Topics: Adolescent; Adult; Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthetics, Local; Catheterizat | 1969 |
EEG frequency content related to regional blood flow of cerebral cortex in cat.
Topics: Animals; Cats; Cerebral Cortex; Cerebrovascular Circulation; Electroencephalography; Fentanyl; Krypt | 1968 |