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pentobarbital and A-V Dissociation

pentobarbital has been researched along with A-V Dissociation in 9 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Research Excerpts

ExcerptRelevanceReference
" In order to study the effects of anesthetic agents on the inducibility of TdP, arrhythmias were induced by programmed electrical stimulation (PES) before and after cumulative intravenous administration of quinidine under anesthesia with sodium pentobarbital, halothane, or isoflurane."7.71Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole. ( Imai, R; Tamura, T; Yamamoto, K; Yamamoto, M, 2001)
" In order to study the effects of anesthetic agents on the inducibility of TdP, arrhythmias were induced by programmed electrical stimulation (PES) before and after cumulative intravenous administration of quinidine under anesthesia with sodium pentobarbital, halothane, or isoflurane."3.71Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole. ( Imai, R; Tamura, T; Yamamoto, K; Yamamoto, M, 2001)
" Apnea followed by rapid shallow breathing was observed in most animals."3.66Cardiovascular and respiratory responses to right atrial injections of phenyl diguanide in pentobarbital-anesthetized newborn piglets. ( Gootman, N; Gootman, PM; Schleman, M, 1979)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19906 (66.67)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Voss, F1
Schreiner, KD1
Senges, JC1
Becker, R1
Bauer, A1
Kuebler, W1
Schoels, W1
BOYER, SH1
CHISHOLM, AW1
MIETTINEN, P1
EEROLA, R1
POENTINEN, P1
Schwartz, JB1
Shen, C1
Garcia, J1
Capili, H1
Sniezek, M1
Yamamoto, K1
Tamura, T1
Imai, R1
Yamamoto, M1
Schleman, M1
Gootman, N1
Gootman, PM1
Bourgeois, MJ1
Gilbert, BK1
Donald, DE1
Wood, EH1
Urthaler, F1
Krames, BL1
James, TN1
Louhimo, I1

Other Studies

9 other studies available for pentobarbital and A-V Dissociation

ArticleYear
Refractory patterns and susceptibility to drug-induced polymorphic ventricular tachycardias in dogs with chronic atrioventricular block: relation to the type of anesthesia.
    Journal of cardiovascular pharmacology, 2002, Volume: 40, Issue:5

    Topics: Adjuvants, Anesthesia; Anesthetics, Inhalation; Animals; Anti-Arrhythmia Agents; Dogs; Drug Interact

2002
Chronotropic responses to sympathomimetic amines in experimental complete heart block: the influence of pentobarbital, hydrocortisone, and acid-base changes.
    Bulletin of the Johns Hopkins Hospital, 1958, Volume: 103, Issue:2

    Topics: Acid-Base Equilibrium; Atrioventricular Block; Heart Block; Hydrocortisone; Pentobarbital; Sympathom

1958
EKG CHANGES DURING SURGERY FOR STRABISMUS.
    Acta ophthalmologica, 1964, Volume: 42

    Topics: Adolescent; Anesthesia; Arrhythmias, Cardiac; Bradycardia; Bundle-Branch Block; Cardiac Complexes, P

1964
Influence of autonomic blockade and aging on AV conduction and responses to verapamil in the beagle.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1995, Volume: 50, Issue:2

    Topics: Aging; Animals; Atrioventricular Node; Atropine; Autonomic Nervous System; Blood Pressure; Dogs; Dos

1995
Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 60, Issue:1

    Topics: Acute Disease; Anesthesia; Anesthetics, Inhalation; Animals; Astemizole; Atrioventricular Node; Cath

2001
Cardiovascular and respiratory responses to right atrial injections of phenyl diguanide in pentobarbital-anesthetized newborn piglets.
    Pediatric research, 1979, Volume: 13, Issue:11

    Topics: Anesthesia, Inhalation; Animals; Animals, Newborn; Aorta; Apnea; Biguanides; Blood Pressure; Bradyca

1979
Characteristics of aortic diastolic pressure decay with application to the continuous monitoring of changes in peripheral vascular resistance.
    Circulation research, 1974, Volume: 35, Issue:1

    Topics: Acetylcholine; Anesthesia, Intravenous; Angiotensin II; Animals; Aorta; Aorta, Thoracic; Blood Press

1974
Selective effects of pentobarbital on automaticity and conduction in the intact canine heart.
    Cardiovascular research, 1974, Volume: 8, Issue:1

    Topics: Acetylcholine; Anesthesia; Animals; Atropine; Blood Pressure; Chloralose; Depression, Chemical; Dogs

1974
Heart injury after blunt thoracic trauma: an experimental study on rabbits.
    Acta chirurgica Scandinavica. Supplementum, 1968, Volume: 380

    Topics: Animals; Aorta; Aortic Rupture; Blood Pressure Determination; Body Weight; Bradycardia; Bundle-Branc

1968