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pentetic acid and Osteosarcoma

pentetic acid has been researched along with Osteosarcoma in 17 studies

Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.

Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"To improve the accuracy of magnetic resonance imaging (MRI) in evaluating the response of osteosarcomas to preoperative chemotherapy, the authors developed a technique of mapping tumor necrosis and viability by quantitating slope values of gadolinium-DTPA (Gd-DTPA) uptake on dynamic fast low-angle shot (FLASH) images."7.68Assessment of osteosarcoma response to preoperative chemotherapy using dynamic FLASH gadolinium-DTPA-enhanced magnetic resonance mapping. ( Fairclough, DL; Fletcher, BD; Hanna, SL; Le, AH; Meyer, WH; Parham, DM, 1992)
"The ability of dynamic, gadolinium-enhanced magnetic resonance (MR) imaging to allow prediction of histologic responses to initial chemotherapy was evaluated in 20 patients with osteosarcoma (n = 12), Ewing sarcoma (n = 4), rhabdomyosarcoma (n = 3), or synovial sarcoma (n = 1)."3.68Pediatric musculoskeletal tumors: use of dynamic, contrast-enhanced MR imaging to monitor response to chemotherapy. ( Fairclough, DL; Fletcher, BD; Gronemeyer, SA; Hanna, SL, 1992)
"A new magnetic resonance (MR) technique, gadolinium-enhanced subtraction MR imaging, was developed to evaluate the response of patients with osteosarcoma to chemotherapy."3.68Osteosarcoma after chemotherapy: evaluation with contrast material-enhanced subtraction MR imaging. ( Charpentier, A; de Baere, T; di Paola, M; Shapeero, LG; Terrier, P; Vanel, D, 1992)
"To improve the accuracy of magnetic resonance imaging (MRI) in evaluating the response of osteosarcomas to preoperative chemotherapy, the authors developed a technique of mapping tumor necrosis and viability by quantitating slope values of gadolinium-DTPA (Gd-DTPA) uptake on dynamic fast low-angle shot (FLASH) images."3.68Assessment of osteosarcoma response to preoperative chemotherapy using dynamic FLASH gadolinium-DTPA-enhanced magnetic resonance mapping. ( Fairclough, DL; Fletcher, BD; Hanna, SL; Le, AH; Meyer, WH; Parham, DM, 1992)
"In nine patients with osteogenic or Ewing sarcoma, we evaluated the use of magnetic resonance angiography (MRA) to assess neovascularity non-invasively in vivo and to monitor response to chemotherapy."2.68Monitoring neovascularity as an indicator to response to chemotherapy in osteogenic and Ewing sarcoma using magnetic resonance angiography. ( Genant, HK; Gooding, CA; Johnston, JO; Lang, P; Matthay, KK; Rosenau, W; Vahlensieck, M, 1996)
"Nude mice bearing osteogenic sarcoma of human origin showed uptake in spiculated pattern."1.27The development and in-vivo behavior of tin containing radiopharmaceuticals--II. Autoradiographic and scintigraphic studies in normal animals and in animal models of bone disease. ( Atkins, HL; Brill, AB; Fairchild, RG; Meinken, GE; Oster, ZH; Richards, P; Sacker, DF; Som, P; Srivastava, SC; Tillman, DY, 1985)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19907 (41.18)18.7374
1990's10 (58.82)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van der Woude, HJ2
Bloem, JL2
Verstraete, KL1
Taminiau, AH2
Nooy, MA2
Hogendoorn, PC2
Holscher, HC1
Hermans, J1
Lang, P1
Vahlensieck, M1
Matthay, KK1
Johnston, JO1
Rosenau, W1
Gooding, CA1
Genant, HK1
Sundaram, M1
Volf, V1
Luz, A1
Schäffer, E1
Müller, WA1
Rencová, J1
Ballou, JE1
Dagle, GE1
McDonald, KE1
Buschbom, RL1
Fletcher, BD2
Hanna, SL2
Fairclough, DL2
Gronemeyer, SA1
de Baere, T1
Vanel, D1
Shapeero, LG1
Charpentier, A1
Terrier, P1
di Paola, M1
Parham, DM1
Meyer, WH1
Le, AH1
Seeger, LL1
Widoff, BE1
Bassett, LW1
Rosen, G1
Eckardt, JJ1
Maas, R2
Winkler, K1
Delling, G1
Heise, U1
Triebel, HJ1
Spielmann, RP1
Härle, A1
Reiser, M1
Erlemann, R1
Wuisman, P1
Pettersson, H1
Eliasson, J1
Egund, N1
Rööser, B1
Willén, H1
Rydholm, A1
Berg, NO1
Holtås, S1
Oster, ZH1
Som, P1
Srivastava, SC1
Fairchild, RG1
Meinken, GE1
Tillman, DY1
Sacker, DF1
Richards, P1
Atkins, HL1
Brill, AB1
Bair, WJ1
Thompson, RC1
Bukhtoiarova, EM1
Lemberg, VK1
Erokhin, RA1
Beliaev, IuA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomised Controlled Trial of the Effects of Fish Oil Emulsion in Total Parenteral Nutrition Upon Tumour Vascularity in Patients With Hepatic Colorectal Metastases[NCT00942292]Phase 220 participants (Actual)Interventional2007-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for pentetic acid and Osteosarcoma

ArticleYear
Plutonium: biomedical research.
    Science (New York, N.Y.), 1974, Feb-22, Volume: 183, Issue:4126

    Topics: Aerosols; Animals; Autoradiography; Body Burden; Bone and Bones; Dogs; Dose-Response Relationship, R

1974

Trials

2 trials available for pentetic acid and Osteosarcoma

ArticleYear
Osteosarcoma and Ewing's sarcoma after neoadjuvant chemotherapy: value of dynamic MR imaging in detecting viable tumor before surgery.
    AJR. American journal of roentgenology, 1995, Volume: 165, Issue:3

    Topics: Adolescent; Adult; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Contrast Media; Drug Combinations;

1995
Monitoring neovascularity as an indicator to response to chemotherapy in osteogenic and Ewing sarcoma using magnetic resonance angiography.
    Medical and pediatric oncology, 1996, Volume: 26, Issue:5

    Topics: Adolescent; Antineoplastic Agents; Bone Neoplasms; Double-Blind Method; Female; Gadolinium DTPA; Hum

1996

Other Studies

14 other studies available for pentetic acid and Osteosarcoma

ArticleYear
Can MRI predict the histopathological response in patients with osteosarcoma after the first cycle of chemotherapy?
    Clinical radiology, 1995, Volume: 50, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Edema; Fem

1995
The use of gadolinium in the MR imaging of bone tumors.
    Seminars in ultrasound, CT, and MR, 1997, Volume: 18, Issue:4

    Topics: Antineoplastic Agents; Bone Neoplasms; Contrast Media; Drug Combinations; Edema; Evaluation Studies

1997
Effect of oral ZnDTPA on late effects of injected plutonium in rat.
    International journal of radiation biology, 1999, Volume: 75, Issue:8

    Topics: Administration, Oral; Animals; Bone and Bones; Bone Neoplasms; Glomerulosclerosis, Focal Segmental;

1999
Influence of inhaled Ca-DTPA on the long-term effects of inhaled Pu nitrate.
    Health physics, 1977, Volume: 32, Issue:6

    Topics: Aerosols; Animals; Body Weight; Bone Neoplasms; Calcium; Dose-Response Relationship, Drug; Dose-Resp

1977
Pediatric musculoskeletal tumors: use of dynamic, contrast-enhanced MR imaging to monitor response to chemotherapy.
    Radiology, 1992, Volume: 184, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Contrast M

1992
Osteosarcoma after chemotherapy: evaluation with contrast material-enhanced subtraction MR imaging.
    Radiology, 1992, Volume: 185, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Combined M

1992
Assessment of osteosarcoma response to preoperative chemotherapy using dynamic FLASH gadolinium-DTPA-enhanced magnetic resonance mapping.
    Investigative radiology, 1992, Volume: 27, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant;

1992
Preoperative evaluation of osteosarcoma: value of gadopentetate dimeglumine-enhanced MR imaging.
    AJR. American journal of roentgenology, 1991, Volume: 157, Issue:2

    Topics: Adolescent; Adult; Aged; Bone Marrow; Bone Neoplasms; Female; Femoral Neoplasms; Gadolinium DTPA; Hu

1991
The potential of MRI in preoperative evaluation of chemotherapy-induced necrosis in osteosarcoma and Ewing's sarcoma.
    La Chirurgia degli organi di movimento, 1990, Volume: 75, Issue:1 Suppl

    Topics: Bone Neoplasms; Contrast Media; Gadolinium DTPA; Humans; Magnetic Resonance Imaging; Necrosis; Organ

1990
[Unusually localized osteosarcoma].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1989, Volume: 150, Issue:5

    Topics: Contrast Media; Female; Gadolinium; Gadolinium DTPA; Humans; Magnetic Resonance Imaging; Middle Aged

1989
[The value of nuclear magnetic resonance tomography in staging of bone and soft tissue sarcomas].
    Der Orthopade, 1989, Volume: 18, Issue:1

    Topics: Bone and Bones; Bone Neoplasms; Contrast Media; Gadolinium DTPA; Humans; Magnetic Resonance Imaging;

1989
Gadolinium-DTPA enhancement of soft tissue tumors in magnetic resonance imaging--preliminary clinical experience in five patients.
    Skeletal radiology, 1988, Volume: 17, Issue:5

    Topics: Adult; Aged; Female; Fibrosarcoma; Gadolinium; Gadolinium DTPA; Humans; Magnetic Resonance Imaging;

1988
The development and in-vivo behavior of tin containing radiopharmaceuticals--II. Autoradiographic and scintigraphic studies in normal animals and in animal models of bone disease.
    International journal of nuclear medicine and biology, 1985, Volume: 12, Issue:3

    Topics: Animals; Bone Diseases; Bone Neoplasms; Fractures, Bone; Humans; Kinetics; Mice; Mice, Nude; Neoplas

1985
[Tumors in rats that have received pentacin after the administration of plutonium-239].
    Voprosy onkologii, 1968, Volume: 14, Issue:8

    Topics: Animals; Bone Neoplasms; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Osteosarcoma; Pentet

1968