pentetic acid has been researched along with Optic Neuritis in 18 studies
Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.
Optic Neuritis: Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To provide magnetic resonance imaging (MRI)-ultrastructural correlations of demyelinating lesions of the intraorbital optic nerve, the authors performed gadolinium-enhanced/T2-weighted fat-suppressed MRI and transmission electron microscopy of the optic nerves of animals with experimental allergic encephalomyelitis." | 3.68 | Intraorbital optic nerve and experimental optic neuritis. Correlation of fat suppression magnetic resonance imaging and electron microscopy. ( Beck, B; Ellis, EA; Fitzsimmons, J; Guy, J; Mancuso, A, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guy, J | 7 |
| McGorray, S | 3 |
| Qi, X | 1 |
| Fitzsimmons, J | 5 |
| Mancuso, A | 6 |
| Rao, N | 1 |
| Takanashi, J | 2 |
| Sugita, K | 2 |
| Fujii, K | 1 |
| Takatsuna, Y | 1 |
| Niimi, H | 2 |
| Simon, JH | 1 |
| Rubinstein, D | 1 |
| Brown, M | 1 |
| Yuh, W | 1 |
| Birch-Iensen, M | 1 |
| Szumowski, J | 1 |
| Stears, J | 1 |
| van der Meyden, CH | 1 |
| de Villiers, JF | 1 |
| Middlecote, BD | 1 |
| Terblanchè, J | 1 |
| Beck, B | 3 |
| Rao, NA | 2 |
| Hamed, L | 1 |
| Morrissey, SP | 1 |
| Miller, DH | 2 |
| Hermaszewski, R | 1 |
| Rudge, P | 1 |
| MacManus, DG | 2 |
| Kendall, B | 1 |
| McDonald, WI | 1 |
| Matsubayashi, J | 1 |
| Sato, K | 1 |
| Sklar, EM | 1 |
| Schatz, NJ | 1 |
| Glaser, JS | 1 |
| Post, MJ | 1 |
| ten Hove, M | 1 |
| Frederiksen, JL | 2 |
| Larsson, HB | 2 |
| Jensen, C | 1 |
| Ohtsuka, K | 1 |
| Hashimoto, M | 1 |
| Miura, M | 1 |
| Nakamura, Y | 1 |
| Christiansen, P | 1 |
| Henriksen, O | 1 |
| Mao, J | 1 |
| Bidgood, WD | 1 |
| Quisling, RG | 2 |
| Ellis, EA | 2 |
| Youl, BD | 1 |
| Turano, G | 1 |
| Towell, AD | 1 |
| Moore, SG | 1 |
| Jones, SJ | 1 |
| Barrett, G | 1 |
| Kendall, BE | 1 |
| Moseley, IF | 1 |
| Barkhof, F | 1 |
| Scheltens, P | 1 |
| Valk, J | 1 |
| Waalewijn, C | 1 |
| Uitdehaag, BM | 1 |
| Polman, CH | 1 |
| Beck, R | 1 |
| Moster, M | 1 |
18 other studies available for pentetic acid and Optic Neuritis
| Article | Year |
|---|---|
Conjugated deferoxamine reduces blood-brain barrier disruption in experimental optic neuritis.
Topics: Animals; Blood-Brain Barrier; Capillary Permeability; Deferoxamine; Disease Models, Animal; Encephal | 1994 |
Optic neuritis with silent cerebral lesions: availability of FLAIR sequences.
Topics: Brain; Child; Contrast Media; Gadolinium DTPA; Humans; Image Enhancement; Magnetic Resonance Imaging | 1995 |
Quantitative contrast-enhanced MR imaging of the optic nerve.
Topics: Adipose Tissue; Contrast Media; Gadolinium; Gadolinium DTPA; Humans; Image Enhancement; Magnetic Res | 1994 |
Gadolinium ring enhancement and mass effect in acute disseminated encephalomyelitis.
Topics: Acute Disease; Biopsy, Needle; Brain; Child; Contrast Media; Dexamethasone; Encephalomyelitis; Follo | 1994 |
Reversals of blood-brain barrier disruption by catalase: a serial magnetic resonance imaging study of experimental optic neuritis.
Topics: Animals; Blood-Brain Barrier; Catalase; Contrast Media; Disease Models, Animal; Encephalomyelitis, A | 1994 |
Disruption of the blood-brain barrier in experimental optic neuritis: immunocytochemical co-localization of H2O2 and extravasated serum albumin.
Topics: Animals; Blood-Brain Barrier; Capillary Permeability; Encephalomyelitis, Autoimmune, Experimental; F | 1994 |
Magnetic resonance imaging of the central nervous system in Behçet's disease.
Topics: Adolescent; Adult; Behcet Syndrome; Brain; Brain Stem; Cerebral Ventricles; Child; Contrast Media; F | 1993 |
Availability of frequency-selective fat-saturation pulse (Fat-Sat) MRI in childhood optic neuritis.
Topics: Adipose Tissue; Artifacts; Child, Preschool; Contrast Media; Gadolinium DTPA; Humans; Image Enhancem | 1996 |
MR of vasculitis-induced optic neuropathy.
Topics: Adult; Arthritis, Rheumatoid; Blood-Brain Barrier; Contrast Media; Drug Combinations; Female; Gadoli | 1996 |
Serial Gadolinium-enhanced MRI in untreated patients with acute optic neuritis: implications for natural history.
Topics: Acute Disease; Adult; Brain; Female; Gadolinium DTPA; Humans; Magnetic Resonance Imaging; Male; Midd | 1997 |
Posterior scleritis with optic perineuritis and internal ophthalmoplegia.
Topics: Adult; Female; Gadolinium DTPA; Humans; Magnetic Resonance Imaging; Ophthalmoplegia; Optic Neuritis; | 1997 |
Gd-DTPA-enhanced lesions in the brain of patients with acute optic neuritis.
Topics: Adult; Blood-Brain Barrier; Brain; Contrast Media; Female; Gadolinium DTPA; Humans; Magnetic Resonan | 1992 |
Enhancement and demyelination of the intraorbital optic nerve. Fat suppression magnetic resonance imaging.
Topics: Adult; Contrast Media; Demyelinating Diseases; Drug Combinations; Female; Gadolinium; Gadolinium DTP | 1992 |
Intraorbital optic nerve and experimental optic neuritis. Correlation of fat suppression magnetic resonance imaging and electron microscopy.
Topics: Adipose Tissue; Animals; Contrast Media; Drug Combinations; Encephalomyelitis, Autoimmune, Experimen | 1992 |
The pathophysiology of acute optic neuritis. An association of gadolinium leakage with clinical and electrophysiological deficits.
Topics: Adolescent; Adult; Electrophysiology; Evoked Potentials, Visual; Gadolinium DTPA; Humans; Magnetic R | 1991 |
Serial quantitative MR assessment of optic neuritis in a case of neuromyelitis optica, using Gadolinium- "enhanced" STIR imaging.
Topics: Adult; Contrast Media; Gadolinium DTPA; Humans; Magnetic Resonance Imaging; Male; Neuromyelitis Opti | 1991 |
Gadolinium-DTPA-enhanced magnetic resonance imaging in optic neuropathies.
Topics: Adolescent; Adult; Aged; Female; Gadolinium DTPA; Humans; Image Enhancement; Magnetic Resonance Imag | 1990 |
Gadolinium-DTPA-enhanced magnetic resonance imaging in experimental optic neuritis.
Topics: Animals; Demyelinating Diseases; Disease Models, Animal; Gadolinium DTPA; Guinea Pigs; Image Enhance | 1990 |