pentetic acid has been researched along with Neurofibromatosis 1 in 12 studies
Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.
Neurofibromatosis 1: An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic NEURAL CREST. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene (GENES, NEUROFIBROMATOSIS 1) on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18) There is overlap of clinical features with NOONAN SYNDROME in a syndrome called neurofibromatosis-Noonan syndrome. Both the PTPN11 and NF1 gene products are involved in the SIGNAL TRANSDUCTION pathway of Ras (RAS PROTEINS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our case occurred in association with neurofibromatosis type 1 and in the absence of an identified primary tumor." | 1.39 | MIBG superscan of metastatic paraganglioma occurring with neurofibromatosis type 1. ( Barron, BJ; Harrison, CE, 2013) |
| "Purely capillary hemangiomas have transient early intense activity while purely cavernous hemangiomas display no early activity but are well visualized on delayed scintigraphic images." | 1.28 | Scintigraphic differentiation of congenital soft-tissue extremity enlargement with Tc-99m DTPA. ( Harcke, HT; Harris, L; Mandell, GA; Scott, CI; Sharkey, C, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (58.33) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harrison, CE | 1 |
| Barron, BJ | 1 |
| Parazzini, C | 1 |
| Triulzi, F | 1 |
| Bianchini, E | 1 |
| Agnetti, V | 1 |
| Conti, M | 1 |
| Zanolini, C | 1 |
| Maninetti, MM | 1 |
| Rossi, LN | 1 |
| Scotti, G | 1 |
| Maini, CL | 1 |
| Cioffi, RP | 1 |
| Tofani, A | 1 |
| Sciuto, R | 1 |
| Fontana, M | 1 |
| Carapella, CM | 1 |
| Crecco, M | 1 |
| Van Es, S | 1 |
| North, KN | 1 |
| McHugh, K | 1 |
| De Silva, M | 1 |
| Kurosaki, Y | 1 |
| Kuramoto, K | 1 |
| Itai, Y | 1 |
| Mandell, GA | 3 |
| Scott, CI | 1 |
| Harcke, HT | 3 |
| Sharkey, C | 3 |
| Harris, L | 1 |
| Dolan, KD | 1 |
| Yuh, WT | 1 |
| Siddiqui, AR | 1 |
| Brooks, KM | 2 |
| MacEwen, GD | 2 |
| Ida, M | 1 |
| Mashima, Y | 1 |
| Mori, Y | 1 |
| Kawakami, K | 1 |
| Kondoh, H | 1 |
| Kaminsky, S | 1 |
| Schulz, B | 1 |
| Herrick, WC | 1 |
12 other studies available for pentetic acid and Neurofibromatosis 1
| Article | Year |
|---|---|
MIBG superscan of metastatic paraganglioma occurring with neurofibromatosis type 1.
Topics: 3-Iodobenzylguanidine; Female; Humans; Middle Aged; Neurofibromatosis 1; Octreotide; Paraganglioma; | 2013 |
Spontaneous involution of optic pathway lesions in neurofibromatosis type 1: serial contrast MR evaluation.
Topics: Adolescent; Child; Child, Preschool; Contrast Media; Cranial Nerve Neoplasms; Drug Combinations; Fem | 1995 |
Indium-111 octreotide scintigraphy in neurofibromatosis.
Topics: Adolescent; Child; Diagnosis, Differential; Female; Humans; Indium Radioisotopes; Male; Middle Aged; | 1995 |
MRI findings in children with neurofibromatosis type 1: a prospective study.
Topics: Brain; Brain Neoplasms; Child; Contrast Media; Drug Combinations; Female; Gadolinium DTPA; Humans; M | 1996 |
Delayed enhancement of peripheral zone of neurofibromas at magnetic resonance imaging.
Topics: Adult; Brain Neoplasms; Contrast Media; Gadolinium; Gadolinium DTPA; Humans; Image Enhancement; Magn | 1996 |
Scintigraphic differentiation of congenital soft-tissue extremity enlargement with Tc-99m DTPA.
Topics: Child; Extremities; Female; Hemangioma; Humans; Lipoma; Male; Neurofibromatosis 1; Organometallic Co | 1989 |
Gadolinium-enhanced facial nerves: accompanying bilateral acoustic tumors in patient with neurofibromatosis.
Topics: Adult; Contrast Media; Facial Nerve; Gadolinium; Gadolinium DTPA; Humans; Magnetic Resonance Imaging | 1989 |
Localization of technetium-99m DTPA in neurofibroma.
Topics: Child; Female; Humans; Lumbosacral Region; Neurofibromatosis 1; Pentetic Acid; Radionuclide Imaging; | 1986 |
SPECT imaging of para-axial neurofibromatosis with technetium-99m DTPA.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Male; Neurofibromatosis 1; Organometalli | 1987 |
[Evaluation of Tc-99m DTPA as tumor seeking agents for neurofibromatosis].
Topics: Adolescent; Adult; Child; Female; Gallium Radioisotopes; Humans; Male; Middle Aged; Neurilemmoma; Ne | 1988 |
[Visualization of multiple neurofibromas using gadolinium-DTPA assisted MRT: a case report].
Topics: Adult; Contrast Media; Gadolinium; Gadolinium DTPA; Humans; Magnetic Resonance Imaging; Male; Neurof | 1988 |
Neurofibromas: location by scanning with Tc-99m DTPA. Work in progress.
Topics: Adolescent; Adult; Child; Female; Humans; Male; Neurofibromatosis 1; Pentetic Acid; Prospective Stud | 1985 |