Page last updated: 2024-10-26

pentetic acid and Neoplasms

pentetic acid has been researched along with Neoplasms in 109 studies

Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"The increased expression of the neurotensin (NT) receptor NTS1 by different cancer cells, such as pancreatic adenocarcinoma and ductal breast cancer cells, as compared to normal epithelium, offers the opportunity to target these tumors with radiolabeled neurotensin analogues for diagnostic or therapeutic purposes."3.75Novel neurotensin analogues for radioisotope targeting to neurotensin receptor-positive tumors. ( Abdelhak, J; Alshoukr, F; Barbet, J; Burg, S; Gruaz-Guyon, A; Maes, V; Pelaprat, D; Raguin, O; Rosant, C; Sarda, L; Tourwé, D, 2009)
"Thirteen (13) patients with liver neuroendocrine carcinomas metastases, positive for somatostatin receptors, confirmed by scintigraphy were infused with 4070-7030 MBq per session of In-111-octreotide after selective hepatic catheterization, exploiting the catastrophic activity of Indium Auger and Internal Conversion electron emission on cell DNA."3.73Evaluation of the therapeutic response to In-111-DTPA octreotide-based targeted therapy in liver metastatic neuroendocrine tumors according to CT/MRI/US findings. ( Dimitriou, P; Dimitropoulos, N; Hatzioannou, A; Kontogeorgakos, D; Koutoulidis, V; Limouris, GS; Lyra, M; Mourikis, D; Papanikolos, G; Stravaka, A; Vlahos, L, 2005)
" This report presents the results of pharmacokinetic and dosimetric studies performed in 24 patients with different tumours."2.69Three-step radioimmunotherapy with yttrium-90 biotin: dosimetry and pharmacokinetics in cancer patients. ( Chinol, M; Cremonesi, M; Ferrari, M; Grana, C; Paganelli, G; Prisco, G; Robertson, C; Stabin, MG; Tosi, G, 1999)
"In developed countries, cancer is the second leading cause of death, being only surpassed by cardiovascular diseases."2.47Radiometallated peptides for molecular imaging and targeted therapy. ( Correia, JD; Paulo, A; Raposinho, PD; Santos, I, 2011)
"The vast majority of human tumors seem to over-express the one or the other of five distinct hSSTR subtype receptors."2.41Experience with indium-111 and yttrium-90-labeled somatostatin analogs. ( Andreae, F; Angelberger, P; Burggasser, G; Dudczak, R; Füger, B; Kurtaran, A; Leimer, M; Li, SR; Novotny, C; Pangerl, T; Patri, P; Raderer, M; Traub, T; Virgolini, I, 2002)
"The value of SRI in patients with other tumors, such as breast cancer or malignant lymphomas, or in patients with granulomatous diseases has to be established."2.41Peptide receptor imaging and therapy. ( de Jong, M; Krenning, EP; Kwekkeboom, D, 2000)
"Nanoparticles' uptake by cancer cells upon reaching the tumor microenvironment is often the rate-limiting step in cancer nanomedicine."1.91Novel Strategy to Drive the Intracellular Uptake of Lipid Nanoparticles for Photodynamic Therapy. ( Bu, J; Chen, J; Cheng, MHY; Ding, L; Guidolin, K; Ho, T; Makky, A; Valic, M; Yau, J; Zheng, G; Zheng, M, 2023)
"To visualize whole cancerous region including hypoxic cancer without radiation exposure, we developed meglumine-gadopentetate-glucose solution for 7."1.62Whole cancer-region enhancement using meglumine-gadopentetate-glucose solution and 7.0-T magnetic resonance imaging. ( Enomoto, T; Hagiwara, O; Matsukiyo, H; Moriyama, H; Sato, E; Sato, Y; Takeda, K; Watanabe, M; Yoshida, R; Yoshida, S; Yoshioka, K, 2021)
"Among different cytokines used for cancer immunotherapy, interleukin-12 (IL-12) has shown great ability as a powerful antitumor and antiangiogenic agent."1.43Enhanced Delivery of Plasmid Encoding Interleukin-12 Gene by Diethylene Triamine Penta-Acetic Acid (DTPA)-Conjugated PEI Nanoparticles. ( Dehshahri, A; Keykhaee, M; Khalvati, B; Sadeghpour, H; Sheikhsaran, F, 2016)
"Colon26 tumors inoculated in the right shoulder were clearly visualized by SPECT 24h after administration."1.43Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging. ( Homma, T; Kanazaki, K; Makino, A; Ono, M; Saji, H; Sano, K; Takahashi, A; Yamauchi, F, 2016)
"The results also showed a good anticancer activity for 99mTc-DTPA-Methionine."1.39A comparative study of two novel nanosized radiolabeled analogues of methionine for SPECT tumor imaging. ( Aghasadeghi, MR; Alavidjeh, MS; Amanlou, M; Ardestani, MS; Daha, FJ; Ebrahimi, SE; Ghorbani, M; Khosroshahi, AG; Mousavi, L; Pouriayevali, MH; Sabzevari, O; Sadat, SM, 2013)
"EGFR is over-expressed in several solid tumors including breast, prostate, pancreas, and lung cancers and is correlated to the metastatic potential of the tumor."1.37Development of anti-EGF receptor peptidomimetics (AERP) as tumor imaging agent. ( Alavi, A; Berezov, A; Greene, MI; Murali, R; Ponde, DE; Su, Z; Zhang, H, 2011)
"U-87MG and BMG tumors saturated at approximately 2000 +/- 280 nmol/kg of (99m)Tc-DTPA-bis(Met)."1.36Synthesis of specific SPECT-radiopharmaceutical for tumor imaging based on methionine: 99mTc-DTPA-bis(methionine). ( Chuttani, K; Goel, V; Hazari, PP; Kumar, N; Mishra, AK; Sharma, R; Shukla, G, 2010)
"Tumors were clearly visualized 1 day after injecting 3."1.36PET imaging of HER1-expressing xenografts in mice with 86Y-CHX-A''-DTPA-cetuximab. ( Baidoo, KE; Brechbiel, MW; Garmestani, K; Milenic, DE; Nayak, TK; Regino, CA; Szajek, LP; Wong, KJ, 2010)
"In mice bearing LS-174T, PC-3, or A431 tumors, the tumor uptake at 3 d was 34."1.36Preparation, biological evaluation, and pharmacokinetics of the human anti-HER1 monoclonal antibody panitumumab labeled with 86Y for quantitative PET of carcinoma. ( Baidoo, KE; Brechbiel, MW; Garmestani, K; Milenic, DE; Nayak, TK, 2010)
"To improve the targeting to tumors expressing the cholecystokinin receptor subtype 2 (CCK2R) with limited kidney uptake, we synthesized a novel cholecystokinin C-terminal tetrapeptide (CCK4)-based derivative conjugated to an original bipyridine-chelator (BPCA), 111In-BPCA-(Ahx)2-CCK4."1.36Development of a new radioligand for cholecystokinin receptor subtype 2 scintigraphy: from molecular modeling to in vivo evaluation. ( Benoist, E; Brillouet, S; Courbon, F; Delord, JP; Dorbes, S; Mestre-Voegtlé, B; Picard, C; Poirot, M; Silvente-Poirot, S, 2010)
"Tracer kinetics in tumors and nontumor tissues and tumor-to-background ratios were described by region-of-interest analysis and standardized uptake values (SUVs)."1.33Gluc-Lys([18F]FP)-TOCA PET in patients with SSTR-positive tumors: biodistribution and diagnostic evaluation compared with [111In]DTPA-octreotide. ( Herz, M; Meisetschläger, G; Poethko, T; Scheidhauer, K; Schottelius, M; Schwaiger, M; Stahl, A; Wester, HJ; Wolf, I, 2006)
"In 21 patients with SSTR-expressing tumors, the semiquantitative region-of-interest analysis showed that (99m)Tc-TOC achieved higher tumor-to-normal tissue ratios than (111)In-OCT."1.32An intrapatient comparison of 99mTc-EDDA/HYNIC-TOC with 111In-DTPA-octreotide for diagnosis of somatostatin receptor-expressing tumors. ( Decristoforo, C; Donnemiller, E; Gabriel, M; Mather, SJ; Moncayo, R; Ulmer, H; Watfah Rychlinski, C, 2003)
"In K1735-M2 and CT-26 tumors, a single treatment with IA-NP-(90)Y (14."1.32A novel antiangiogenesis therapy using an integrin antagonist or anti-Flk-1 antibody coated 90Y-labeled nanoparticles. ( Bednarski, MD; Choi, HS; Chu, P; Danthi, SN; Dechene, N; Doede, T; Knox, SJ; Lee, DY; Li, L; Ning, S; Pease, J; Shen, Z; Wartchow, CA, 2004)
"ACTH-secreting tumors were localized in 13 patients and were occult in four."1.32The role of [(18)F]fluorodeoxyglucose positron emission tomography and [(111)In]-diethylenetriaminepentaacetate-D-Phe-pentetreotide scintigraphy in the localization of ectopic adrenocorticotropin-secreting tumors causing Cushing's syndrome. ( Carrasquillo, JA; Chen, CC; Ilias, I; Nieman, LK; Pacak, K; Whatley, M, 2004)
"Int."1.31Evaluation of a radiolabelled cyclic DTPA-RGD analogue for tumour imaging and radionuclide therapy. ( Bernard, HF; Breeman, WA; de Jong, M; Krenning, EP; Mooij, CM; Schaar, M; Schmidt, MA; Srinivasan, A; van Hagen, PM, 2000)
"The uptake in the lung tumors was at an intermediate level (18."1.31Effective targeting of solid tumors in patients with locally advanced cancers by radiolabeled pegylated liposomes. ( Glass, D; Harrington, KJ; Mohammadtaghi, S; Peters, AM; Stewart, JS; Uster, PS; Vile, RG, 2001)
"For deep-lying tumors the NaI(TI) detector was superior, whereas the CdTe detector was best suited for superficial tumors with a high activity concentration in the underlying tissue."1.30Evaluation of three gamma detectors for intraoperative detection of tumors using 111In-labeled radiopharmaceuticals. ( Ahlman, H; Benjegård, SA; Bernhardt, P; Forssell-Aronsson, E; Sauret, V; Wängberg, B, 1999)
" Because renal excretion is the major variable determining the pharmacokinetics of this drug, a dosing formula based on glomerular filtration rate (GFR) has been proposed and is being increasingly used in carboplatin dosing."1.29Carboplatin dosing based on measurement of renal function--experience at the Peter MacCallum Cancer Institute. ( Bishop, JF; Hicks, R; Johnston, VK; Millward, MJ; Rischin, D; Stokes, KH; Toner, GC; Webster, LK, 1996)
"Somatostatin receptor-positive human tumors can be detected using radioiodinated analogues of somatostatin, both in vitro and in vivo."1.28[111In-DTPA-D-Phe1]-octreotide, a potential radiopharmaceutical for imaging of somatostatin receptor-positive tumors: synthesis, radiolabeling and in vitro validation. ( Albert, R; Bakker, WH; Breeman, WA; Bruns, C; Hofland, LJ; Koper, JW; Marbach, P; Pless, J; Pralet, D; Stolz, B, 1991)
" In addition, pharmacokinetic studies assessed the ability of C46-GYK-DTPA labeled with 111In to localize to and image human tumor xenografts in nude mice."1.28Carbohydrate-derivatized immunoconjugate of the anti-(carcinoembryonic antigen) monoclonal antibody C46: immunohistological reactivity and pharmacokinetic comparison with a randomly derivatized C46 immunoconjugate. ( D'Aleo, CJ; Davis, WL; Gilman, SC; Lopes, AD; Rosenstraus, MJ, 1990)
" The MR examination included various plain T1 and T2 weighted spin echo sequences as well as T1 weighted examinations after intravenous application of Gadolinium-DTPA ("Magnevist", Schering AG) in a dosage of 0."1.28[Gadolinium-DTPA in magnetic resonance tomography. Clinical use--indications]. ( Imhof, H; Kramer, J; Prayer, L; Stiglbauer, R; Wimberger, D, 1989)
"In 11 patients with various primary tumors, local recurrences or metastases [colorectal carcinoma (n = 7), ovarian carcinoma (n = 2), papillary thyroid carcinoma (n = 1), undifferentiated carcinoma of the lung (n = 1)], immunoscintigraphy (IS) was carried out using 111In-DTPA-labeled F(ab')2 fragments of various MAbs (anti-CEA, OC 125, anti-hTG) and planar and tomographic imaging were compared intra-individually."1.27[Immunoscintigraphy using 111In-DTPA-labeled monoclonal antibodies: comparison with ECT and planar scintigraphy]. ( Baum, RP; Brandhorst, I; Frohn, J; Halbsguth, A; Happ, J; Hör, G; Lochner, B; Weimer, B, 1987)
"Rhenium-186 has been theoretically determined to be among the best therapy radiolabels due to its unique half-life, particulate and gamma emissions and chelation properties."1.27Radiolabeled biomolecules with 186Re: potential for radioimmunotherapy. ( Quadri, SM; Wessels, BW, 1986)
"A total of 14 cancer patients were studied, nine with identifiable sites of metastatic disease from colorectal [8], pancreatic [2], ovarian [3], or small cell lung [1] primaries."1.27Pharmacokinetics of an indium-111-labeled monoclonal antibody in cancer patients. ( Childs, RL; Doherty, PW; Griffin, TW; Hnatowich, DJ; Kosciuczyk, C; Mattis, JA; Rusckowski, M; Shealy, D, 1985)
"In all, 39 patients with advanced cancer were treated at doses of 2."1.27Phase I study of the cisplatin analogue 1,1-diamminomethylcyclohexane sulfatoplatinum (TNO-6) (NSC 311056). ( Groth, S; Hansen, HH; Hansen, SW; Nissen, MH; Rørth, M; Sørensen, JB, 1985)

Research

Studies (109)

TimeframeStudies, this research(%)All Research%
pre-199019 (17.43)18.7374
1990's30 (27.52)18.2507
2000's32 (29.36)29.6817
2010's20 (18.35)24.3611
2020's8 (7.34)2.80

Authors

AuthorsStudies
Diamandis, P1
Wildenhain, J1
Clarke, ID1
Sacher, AG1
Graham, J1
Bellows, DS1
Ling, EK1
Ward, RJ1
Jamieson, LG1
Tyers, M1
Dirks, PB1
Xu, R1
Chi, W1
Zhao, Y1
Tang, Y1
Jing, X1
Wang, Z2
Zhou, Y1
Shen, Q1
Zhang, J1
Yang, Z1
Dang, D1
Meng, L1
Margalik, DA1
Chen, J2
Ho, T2
Ding, L2
Dhaliwal, A1
Doria, AS1
Zheng, G2
Guidolin, K1
Makky, A1
Valic, M1
Bu, J1
Zheng, M1
Cheng, MHY1
Yau, J1
Tang, S1
Li, G1
Zhang, H2
Bao, Y1
Wu, X1
Yan, R1
Jin, Y1
Hosseini, SM1
Mohammadnejad, J1
Yousefnia, H1
Alirezapour, B1
Rezayan, AH1
Zhang, Y1
Liu, D1
Qiao, B1
Luo, Y1
Yang, C1
Zhang, L1
Cao, Y1
Ran, H1
Luca, S1
Verdoliva, V1
Saviano, M1
Sato, E1
Yoshida, S1
Takeda, K1
Yoshida, R1
Sato, Y1
Yoshioka, K1
Moriyama, H1
Hagiwara, O1
Matsukiyo, H1
Enomoto, T1
Watanabe, M1
Yamamoto, T1
Kabus, S1
Kanazaki, K2
Sano, K3
Makino, A2
Takahashi, A2
Deguchi, J1
Ohashi, M1
Temma, T1
Ono, M2
Saji, H3
Hazari, PP2
Prakash, S1
Meena, VK1
Jaswal, A1
Khurana, H1
Mishra, SK1
Bhonsle, HK1
Singh, L1
Mishra, AK3
Li, JJ1
Lan, KL1
Chang, SF1
Chen, YF1
Tsai, WC1
Chiang, PH1
Lin, MH1
Fischer, WB1
Shih, YS1
Yen, SH1
Liu, RS1
Tsay, YG1
Wang, HE1
Chang, CA1
Dehshahri, A1
Sadeghpour, H1
Keykhaee, M1
Khalvati, B1
Sheikhsaran, F1
Yamauchi, F1
Homma, T1
Stammes, MA1
Knol-Blankevoort, VT1
Cruz, LJ1
Feitsma, HR1
Mezzanotte, L1
Cordfunke, RA1
Sinisi, R1
Dubikovskaya, EA1
Maeda, A1
DaCosta, RS1
Bierau, K1
Chan, A1
Kaijzel, EL1
Snoeks, TJ1
van Beek, ER1
Löwik, CW1
Hagimori, M1
Hatabe, E1
Miyazaki, H1
Sasaki, H1
Mukai, T1
Xiong, QF1
Chen, Y1
Alshoukr, F1
Rosant, C1
Maes, V1
Abdelhak, J1
Raguin, O1
Burg, S1
Sarda, L1
Barbet, J1
Tourwé, D1
Pelaprat, D1
Gruaz-Guyon, A1
Müssig, K1
Oksüz, MO1
Pfannenberg, C1
Adam, P1
Zustin, J1
Beckert, S1
Petersenn, S1
Shukla, G1
Goel, V1
Chuttani, K2
Kumar, N1
Sharma, R1
Nayak, TK2
Regino, CA1
Wong, KJ1
Milenic, DE2
Garmestani, K2
Baidoo, KE2
Szajek, LP1
Brechbiel, MW4
Brillouet, S1
Dorbes, S1
Courbon, F1
Picard, C1
Delord, JP1
Benoist, E1
Poirot, M1
Mestre-Voegtlé, B1
Silvente-Poirot, S1
Kakkar, D1
Tiwari, AK1
Kaul, A1
Singh, H1
Josan, JS1
De Silva, CR1
Yoo, B1
Lynch, RM1
Pagel, MD1
Vagner, J1
Hruby, VJ1
Park, D1
Don, AS1
Massamiri, T1
Karwa, A1
Warner, B1
MacDonald, J1
Hemenway, C1
Naik, A1
Kuan, KT1
Dilda, PJ1
Wong, JW1
Camphausen, K1
Chinen, L1
Dyszlewski, M1
Hogg, PJ1
Correia, JD1
Paulo, A1
Raposinho, PD1
Santos, I1
Ponde, DE1
Su, Z1
Berezov, A1
Alavi, A1
Greene, MI1
Murali, R1
Maecke, HR2
Reubi, JC5
Laverman, P1
Sosabowski, JK1
Boerman, OC1
Oyen, WJ1
Khosroshahi, AG1
Amanlou, M1
Sabzevari, O1
Daha, FJ1
Aghasadeghi, MR1
Ghorbani, M1
Ardestani, MS1
Alavidjeh, MS1
Sadat, SM1
Pouriayevali, MH1
Mousavi, L1
Ebrahimi, SE1
Virgolini, I2
Traub, T1
Novotny, C1
Leimer, M2
Füger, B1
Li, SR1
Patri, P1
Pangerl, T1
Angelberger, P2
Raderer, M2
Burggasser, G1
Andreae, F1
Kurtaran, A2
Dudczak, R1
Weiner, RE1
Thakur, ML1
Hosseinkhani, H1
Aoyama, T1
Ogawa, O1
Tabata, Y2
Gabriel, M1
Decristoforo, C1
Donnemiller, E1
Ulmer, H1
Watfah Rychlinski, C1
Mather, SJ1
Moncayo, R1
ROSENTHAL, MW2
MARKLEY, JF2
LINDENBAUM, A2
Wen, X1
Wu, QP1
Ke, S1
Wallace, S1
Charnsangavej, C1
Huang, P1
Liang, D1
Chow, D1
Li, C1
Ke, CY2
Mathias, CJ2
Green, MA2
Khawli, LA1
Alauddin, MM1
Hu, P1
Epstein, AL1
Li, L1
Wartchow, CA1
Danthi, SN1
Shen, Z1
Dechene, N1
Pease, J1
Choi, HS1
Doede, T1
Chu, P1
Ning, S1
Lee, DY1
Bednarski, MD1
Knox, SJ1
Pacak, K1
Ilias, I1
Chen, CC1
Carrasquillo, JA1
Whatley, M1
Nieman, LK1
Bernard, B1
Capello, A1
van Hagen, M1
Breeman, W1
Srinivasan, A3
Schmidt, M1
Erion, J2
van Gameren, A1
Krenning, E1
de Jong, M6
Forssell-Aronsson, E3
Bernhardt, P2
Nilsson, O2
Tisell, LE1
Wängberg, B3
Ahlman, H3
Kwekkeboom, DJ4
Mueller-Brand, J1
Paganelli, G2
Anthony, LB2
Pauwels, S1
Kvols, LK1
O'dorisio, TM1
Valkema, R3
Bodei, L1
Chinol, M2
Krenning, EP8
Limouris, GS1
Dimitropoulos, N1
Kontogeorgakos, D1
Papanikolos, G1
Koutoulidis, V1
Hatzioannou, A1
Mourikis, D1
Lyra, M1
Dimitriou, P1
Stravaka, A1
Vlahos, L1
Berndorff, D1
Borkowski, S1
Sieger, S1
Rother, A1
Friebe, M1
Viti, F1
Hilger, CS1
Cyr, JE1
Dinkelborg, LM1
Boswell, CA1
Meisetschläger, G1
Poethko, T1
Stahl, A1
Wolf, I1
Scheidhauer, K1
Schottelius, M1
Herz, M1
Wester, HJ1
Schwaiger, M1
Lewis, I1
Albert, R2
Kneuer, R1
Pless, J2
Simeon, C1
Kerrad, S1
Hoyer, D1
Bruns, C3
Liu, J1
Ohta, S1
Sonoda, A1
Yamada, M2
Yamamoto, M1
Nitta, N1
Murata, K1
de Korte, MA1
de Vries, EG1
Lub-de Hooge, MN1
Jager, PL1
Gietema, JA1
van der Graaf, WT1
Sluiter, WJ1
van Veldhuisen, DJ1
Suter, TM1
Sleijfer, DT1
Perik, PJ1
Wesbey, GE1
Engelstad, BL1
Brasch, RC1
Carr, DH1
Lamberts, SW2
Visser, TJ2
Bakker, WH4
Kooij, PP3
Rubin, PA1
Bilyk, JR1
Shore, JW1
Sutula, FC1
Cheng, HM1
Westlin, JE3
Ahlström, H1
Ylä-Jääski, J2
Oberg, K1
Nilsson, S3
van Osdol, WW1
Sung, C1
Dedrick, RL1
Weinstein, JN1
Arnberg, H1
Husin, S1
Li, S1
Yang, Q1
Neuhold, N1
Kaserer, K1
Peck-Radosavljevic, M1
Scheithauer, W1
Niederle, B1
Eichler, HG1
Valent, P1
Steens, J1
Cleton, FJ1
Pauwels, EK1
Millward, MJ1
Webster, LK1
Toner, GC1
Bishop, JF1
Rischin, D1
Stokes, KH1
Johnston, VK1
Hicks, R1
Harrison, KA1
Tempero, MA1
Uno, K1
Kuyama, J1
Uchida, Y1
Sakata, S1
Kitakata, Y1
Waser, B1
Schaer, JC1
Laederach, U1
Schmidt, MA2
Bugaj, JE1
Hosono, M1
Cremonesi, M1
Ferrari, M1
Stabin, MG1
Grana, C1
Prisco, G1
Robertson, C1
Tosi, G1
Espenan, GD1
Nelson, JA1
Fisher, DR1
Diaco, DS1
McCarthy, KE1
Maloney, TJ1
Woltering, EA1
Schörner, W1
Lang, P1
Bittner, R1
Felix, R2
Jones-Bey, H1
Benjegård, SA2
Sauret, V1
Kälkner, KM1
van Hagen, PM1
Breeman, WA4
Bernard, HF1
Schaar, M1
Mooij, CM1
Kwekkeboom, D1
Ong, GL1
Elsamra, SE1
Goldenberg, DM1
Mattes, MJ1
Gabizon, AA1
Harrington, KJ1
Mohammadtaghi, S1
Uster, PS1
Glass, D1
Peters, AM1
Vile, RG1
Stewart, JS1
Skånberg, J1
Lugtenburg, PJ1
De Jong, FH1
Christiansen, A1
Kam, BL1
De Herder, WW1
Stridsberg, M1
Lindemans, J1
Ensing, G1
Ballou, JE1
Dagle, GE1
McDonald, KE1
Buschbom, RL1
Oei, HY1
Barzen, G1
Ochi, K1
Fujii, T1
Kimura, Y1
Akamune, A1
Hamamoto, K2
Hofland, LJ1
Marbach, P1
Pralet, D1
Stolz, B1
Koper, JW1
Erlemann, R1
Stöber, U1
Drews, C1
Böcker, D1
Peters, PE1
Hnatowich, DJ3
Sandring, KH1
Lüning, M1
Rosenstraus, MJ1
Davis, WL1
Lopes, AD1
D'Aleo, CJ1
Gilman, SC1
Fletcher, BD1
Hanna, SL1
Chu, TM1
Itai, Y1
Hicks, RJ1
Kalff, V1
Brazenor, G1
Rahmat, H1
Kelly, MJ1
Keenan, AM1
Harbert, JC1
Larson, SM1
Prayer, L1
Imhof, H1
Stiglbauer, R1
Kramer, J1
Wimberger, D1
Snook, D1
Rowlinson, G1
Stewart, S1
Epenetos, AA1
Tanada, S1
Mogami, H1
Mochizuki, T1
Miyagawa, M1
Yasuhara, Y1
Iio, A1
Zuckier, LS1
Weissmann, HS1
Kaplun, L1
Schlossberg, I1
Gade, MF1
Freeman, LM1
Happ, J1
Baum, RP1
Frohn, J1
Weimer, B1
Halbsguth, A1
Lochner, B1
Brandhorst, I1
Hör, G1
Quadri, SM1
Wessels, BW1
Griffin, TW1
Kosciuczyk, C1
Rusckowski, M1
Childs, RL1
Mattis, JA1
Shealy, D1
Doherty, PW1
Sørensen, JB1
Groth, S1
Hansen, SW1
Nissen, MH1
Rørth, M1
Hansen, HH1
Norwood, WD1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Peptide Receptor Radionuclide Therapy (PRRT) in Tumors With High Expression of Somatostatin Receptors[NCT04790708]250 participants (Anticipated)Interventional2018-07-02Recruiting
Molecular and Whole-body MR Imaging in Lymphomas[NCT02389101]21 participants (Actual)Interventional2014-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

68Ga-DOTANOC Uptake in Lymphomas With PET/CT

Uptake of 68Ga-DOTANOC in lymphoma expressed as SUVmax (NCT02389101)
Timeframe: Within 30 days prior to start of chemotherapy

InterventionStandardized Uptake Value (Median)
Lymphoma3.1

Reviews

24 reviews available for pentetic acid and Neoplasms

ArticleYear
Review: Deoxyglucose compounds labeled with isotopes different from 18-fuoride: is there a future in clinical practice?
    Cancer biotherapy & radiopharmaceuticals, 2008, Volume: 23, Issue:3

    Topics: Animals; Deoxyglucose; Diagnostic Imaging; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; M

2008
Radiometallated peptides for molecular imaging and targeted therapy.
    Dalton transactions (Cambridge, England : 2003), 2011, Jun-21, Volume: 40, Issue:23

    Topics: Coordination Complexes; Humans; Metals; Neoplasms; Pentetic Acid; Peptides; Radiopharmaceuticals; Re

2011
Radiolabelled peptides for oncological diagnosis.
    European journal of nuclear medicine and molecular imaging, 2012, Volume: 39 Suppl 1

    Topics: Animals; Bombesin; Cholecystokinin; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Human

2012
Experience with indium-111 and yttrium-90-labeled somatostatin analogs.
    Current pharmaceutical design, 2002, Volume: 8, Issue:20

    Topics: Heterocyclic Compounds; Humans; Indium Radioisotopes; Neoplasms; Octreotide; Pentetic Acid; Peptides

2002
Radiolabeled peptides in the diagnosis and therapy of oncological diseases.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2002, Volume: 57, Issue:5

    Topics: Humans; Intercellular Signaling Peptides and Proteins; Neoplasms; Octreotide; Pentetic Acid; Peptide

2002
The folate receptor as a molecular target for tumor-selective radionuclide delivery.
    Nuclear medicine and biology, 2003, Volume: 30, Issue:8

    Topics: Animals; Biomarkers, Tumor; Carrier Proteins; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Ne

2003
Overview of results of peptide receptor radionuclide therapy with 3 radiolabeled somatostatin analogs.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005, Volume: 46 Suppl 1

    Topics: Animals; Clinical Trials as Topic; Drug Delivery Systems; Drug Evaluation, Preclinical; Gastrointest

2005
Overview of results of peptide receptor radionuclide therapy with 3 radiolabeled somatostatin analogs.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005, Volume: 46 Suppl 1

    Topics: Animals; Clinical Trials as Topic; Drug Delivery Systems; Drug Evaluation, Preclinical; Gastrointest

2005
Overview of results of peptide receptor radionuclide therapy with 3 radiolabeled somatostatin analogs.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005, Volume: 46 Suppl 1

    Topics: Animals; Clinical Trials as Topic; Drug Delivery Systems; Drug Evaluation, Preclinical; Gastrointest

2005
Overview of results of peptide receptor radionuclide therapy with 3 radiolabeled somatostatin analogs.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005, Volume: 46 Suppl 1

    Topics: Animals; Clinical Trials as Topic; Drug Delivery Systems; Drug Evaluation, Preclinical; Gastrointest

2005
Somatostatin and the concept of peptide receptor scintigraphy in oncology.
    Seminars in oncology, 1994, Volume: 21, Issue:5 Suppl 13

    Topics: Humans; Indium Radioisotopes; Iodine Radioisotopes; Neoplasms; Octreotide; Pentetic Acid; Radionucli

1994
Essentials of peptide receptor scintigraphy with emphasis on the somatostatin analog octreotide.
    Seminars in oncology, 1994, Volume: 21, Issue:5 Suppl 13

    Topics: Humans; Indium Radioisotopes; Iodine Radioisotopes; Neoplasms; Octreotide; Pentetic Acid; Radionucli

1994
The diagnostic utility of somatostatin receptor scintigraphy in oncology.
    Journal of cancer research and clinical oncology, 1996, Volume: 122, Issue:9

    Topics: Amino Acid Sequence; Humans; Indium Radioisotopes; Molecular Sequence Data; Neoplasms; Octreotide; P

1996
Diagnostic use of radiolabeled antibodies for cancer.
    Oncology (Williston Park, N.Y.), 1995, Volume: 9, Issue:7

    Topics: Antibodies, Monoclonal; Antibodies, Neoplasm; Antigens, Neoplasm; Humans; Indium Radioisotopes; Neop

1995
[Tumor imaging in nuclear medicine].
    Nihon rinsho. Japanese journal of clinical medicine, 1996, Volume: 54, Issue:5

    Topics: Citric Acid; Gallium Radioisotopes; Gamma Cameras; Humans; Indium Radioisotopes; Neoplasms; Octreoti

1996
Radiolabeled somatostatin analog scintigraphy in oncology and immune diseases: an overview.
    European radiology, 1997, Volume: 7, Issue:7

    Topics: Humans; Indium Radioisotopes; Neoplasms; Neuroendocrine Tumors; Octreotide; Pentetic Acid; Radiophar

1997
[Nuclear oncology with monoclonal antibodies and peptides].
    Kaku igaku. The Japanese journal of nuclear medicine, 1998, Volume: 35, Issue:8

    Topics: Animals; Antibodies, Monoclonal; Humans; Indium Radioisotopes; Iodine Radioisotopes; Mice; Neoplasms

1998
Gd-DTPA enhances uses for MR imaging of body.
    Diagnostic imaging, 1990, Volume: 12, Issue:4

    Topics: Cardiomyopathies; Contrast Media; Gadolinium; Humans; Magnetic Resonance Imaging; Musculoskeletal Di

1990
Peptide receptor imaging and therapy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2000, Volume: 41, Issue:10

    Topics: Humans; Indium Radioisotopes; Neoplasms; Neuroendocrine Tumors; Octreotide; Oligopeptides; Pentetic

2000
Chelated metal ions for therapeutic and diagnostic applications.
    Experimental biology and medicine (Maywood, N.J.), 2001, Volume: 226, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Bismuth; Chelating Agents; Humans; Isotope Labeling; Isotopes; Meta

2001
[Radioimmunoscintigraphy: fundamentals (1)].
    Aktuelle Radiologie, 1992, Volume: 2, Issue:5

    Topics: Contrast Media; Gadolinium; Gadolinium DTPA; Humans; Iodine Radioisotopes; Neoplasms; Organometallic

1992
Radiolabeling antibodies via the cyclic anhydride of DTPA--experiences of 5 years.
    Cancer treatment and research, 1990, Volume: 51

    Topics: Antibodies, Monoclonal; Humans; Isotope Labeling; Liver; Neoplasms; Pentetic Acid; Radionuclide Imag

1990
[Magnetic resonance tomography of the whole body--methodology and clinical results].
    Zeitschrift fur arztliche Fortbildung, 1990, Volume: 84, Issue:24

    Topics: Cardiovascular Diseases; Contrast Media; Gadolinium DTPA; Humans; Magnetic Resonance Imaging; Neopla

1990
Potential applications of monoclonal antibodies in cancer diagnosis and therapy.
    Cancer investigation, 1985, Volume: 3, Issue:6

    Topics: Adenocarcinoma; alpha-Fetoproteins; Animals; Antibodies, Monoclonal; Antibody Specificity; Antigens,

1985
[MRI and MRS in the diagnosis of cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:3 Pt 2

    Topics: Carcinoma, Hepatocellular; Contrast Media; Diagnosis, Differential; Gadolinium DTPA; Hemangioma, Cav

1989
Monoclonal antibodies in nuclear medicine.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1985, Volume: 26, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Antibody Affinity; Epitopes; Genes, MHC Class II; Humans; Hybridoma

1985
Preparation and use of DTPA-coupled antitumor antibodies radiolabeled with yttrium-90.
    Targeted diagnosis and therapy, 1988, Volume: 1

    Topics: Animals; Antibodies, Monoclonal; Drug Carriers; Humans; Mice; Mice, Nude; Neoplasms; Pentetic Acid;

1988

Trials

4 trials available for pentetic acid and Neoplasms

ArticleYear
Technical Note: Correction for the effect of breathing variations in CT pulmonary ventilation imaging.
    Medical physics, 2018, Volume: 45, Issue:1

    Topics: Abdomen; Four-Dimensional Computed Tomography; Humans; Lung; Motion; Neoplasms; Organotechnetium Com

2018
Three-dimensional OctreoScan111 SPECT of abdominal manifestation of neuroendocrine tumours.
    Acta oncologica (Stockholm, Sweden), 1993, Volume: 32, Issue:2

    Topics: Abdominal Neoplasms; Carcinoid Tumor; Female; Humans; Image Processing, Computer-Assisted; Indium Ra

1993
Three-step radioimmunotherapy with yttrium-90 biotin: dosimetry and pharmacokinetics in cancer patients.
    European journal of nuclear medicine, 1999, Volume: 26, Issue:2

    Topics: Antibodies, Monoclonal; Avidin; Biotinylation; Bone Marrow; Chelating Agents; Heterocyclic Compounds

1999
Phase I study of peptide receptor radionuclide therapy with [In-DTPA]octreotide: the Rotterdam experience.
    Seminars in nuclear medicine, 2002, Volume: 32, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Neoplasms; Neuroendocrine Tumors;

2002

Other Studies

81 other studies available for pentetic acid and Neoplasms

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic

2007
All-in-One Theranostic Platforms: Deep-Red AIE Nanocrystals to Target Dual-Organelles for Efficient Photodynamic Therapy.
    ACS nano, 2022, 12-27, Volume: 16, Issue:12

    Topics: Humans; Nanoparticles; Neoplasms; Organelles; Pentetic Acid; Photochemotherapy; Photosensitizing Age

2022
Prolonged Circulating Lipid Nanoparticles Enabled by High-Density Gd-DTPA-Bis(stearylamide) for Long-Lasting Enhanced Tumor Magnetic Resonance Imaging.
    Bioconjugate chemistry, 2022, 11-16, Volume: 33, Issue:11

    Topics: Animals; Contrast Media; Gadolinium DTPA; Lipids; Liposomes; Magnetic Resonance Imaging; Mice; Neopl

2022
Novel Strategy to Drive the Intracellular Uptake of Lipid Nanoparticles for Photodynamic Therapy.
    Angewandte Chemie (International ed. in English), 2023, 04-11, Volume: 62, Issue:16

    Topics: Cell Line, Tumor; Edetic Acid; Humans; Lipids; Liposomes; Nanoparticles; Neoplasms; Pentetic Acid; P

2023
Organic disulfide-modified folate carbon dots for tumor-targeted synergistic chemodynamic/photodynamic therapy.
    Biomaterials science, 2023, May-02, Volume: 11, Issue:9

    Topics: Carbon; Cell Line, Tumor; Disulfides; Folic Acid; Glutathione; Humans; Hydrogen Peroxide; Nanopartic

2023
Development of
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:10

    Topics: Animals; Cell Line, Tumor; Cetuximab; ErbB Receptors; Immunoconjugates; Mice; Mice, Nude; Neoplasms;

2023
Bi-DTPA, a potential CT-guided radiation sensitizer.
    Biochemical and biophysical research communications, 2023, 09-03, Volume: 671

    Topics: Humans; Neoplasms; Pentetic Acid; Radiation Tolerance; Radiation-Sensitizing Agents; Tomography, X-R

2023
Peptide Ligands Specifically Targeting HER2 Receptor and the Role Played by a Synthetic Model System of the Receptor Extracellular Domain: Hypothesized Future Perspectives.
    Journal of medicinal chemistry, 2020, 12-24, Volume: 63, Issue:24

    Topics: Animals; Binding Sites; Humans; Immunoconjugates; Isotope Labeling; Ligands; Magnetic Resonance Imag

2020
Whole cancer-region enhancement using meglumine-gadopentetate-glucose solution and 7.0-T magnetic resonance imaging.
    Magnetic resonance imaging, 2021, Volume: 81

    Topics: Contrast Media; Gadolinium DTPA; Glucose; Humans; Magnetic Resonance Imaging; Meglumine; Neoplasms;

2021
Development of human serum albumin conjugated with near-infrared dye for photoacoustic tumor imaging.
    Journal of biomedical optics, 2014, Volume: 19, Issue:9

    Topics: Animals; Cell Line, Tumor; Female; Humans; Indium Radioisotopes; Indocyanine Green; Mice; Mice, Inbr

2014
LAT1 targeted delivery of methionine based imaging probe derived from M(III) metal ions for early diagnosis of proliferating tumours using molecular imaging modalities.
    Current cancer drug targets, 2015, Volume: 14, Issue:9

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; Early Detection of Cancer; Fe

2015
Development and Characterization of the Recombinant Human VEGF-EGF Dual-Targeting Fusion Protein as a Drug Delivery System.
    Bioconjugate chemistry, 2015, Dec-16, Volume: 26, Issue:12

    Topics: Animals; Antineoplastic Agents; Cattle; Cell Line; Cell Line, Tumor; Drug Carriers; Drug Delivery Sy

2015
Enhanced Delivery of Plasmid Encoding Interleukin-12 Gene by Diethylene Triamine Penta-Acetic Acid (DTPA)-Conjugated PEI Nanoparticles.
    Applied biochemistry and biotechnology, 2016, Volume: 179, Issue:2

    Topics: Cell Proliferation; Gene Transfer Techniques; Genetic Vectors; Hep G2 Cells; Humans; Hydrophobic and

2016
Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging.
    Journal of controlled release : official journal of the Controlled Release Society, 2016, Mar-28, Volume: 226

    Topics: Animals; Cell Line, Tumor; Coloring Agents; Drug Carriers; Indium Radioisotopes; Indocyanine Green;

2016
Pre-clinical Evaluation of a Cyanine-Based SPECT Probe for Multimodal Tumor Necrosis Imaging.
    Molecular imaging and biology, 2016, Volume: 18, Issue:6

    Topics: Animals; Carbocyanines; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Indium Radioisotop

2016
An Activatable Fluorescent γ-Polyglutamic Acid Complex for Sentinel Lymph Node Imaging.
    Biological & pharmaceutical bulletin, 2017, Volume: 40, Issue:3

    Topics: Animals; Dendrimers; Fluorescence; Fluorescent Dyes; Humans; Lymphatic Metastasis; Lysosomes; Male;

2017
Novel neurotensin analogues for radioisotope targeting to neurotensin receptor-positive tumors.
    Bioconjugate chemistry, 2009, Aug-19, Volume: 20, Issue:8

    Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Indium Radioisotopes; L

2009
Somatostatin receptor expression in an epitheloid hemangioma causing oncogenic osteomalacia.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:11

    Topics: Hemangioma; Humans; Hypophosphatemia; Indium Radioisotopes; Male; Middle Aged; Neoplasms; Octreotide

2009
Synthesis of specific SPECT-radiopharmaceutical for tumor imaging based on methionine: 99mTc-DTPA-bis(methionine).
    Bioconjugate chemistry, 2010, Feb-17, Volume: 21, Issue:2

    Topics: Adult; Aged; Animals; Biological Transport; Cell Line, Tumor; Chelating Agents; Drug Stability; Fema

2010
PET imaging of HER1-expressing xenografts in mice with 86Y-CHX-A''-DTPA-cetuximab.
    European journal of nuclear medicine and molecular imaging, 2010, Volume: 37, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cell Line, Tumor; Cell Transform

2010
Preparation, biological evaluation, and pharmacokinetics of the human anti-HER1 monoclonal antibody panitumumab labeled with 86Y for quantitative PET of carcinoma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Volume: 51, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Area Under Curve; Biological Transport; Cell Line, Tumor; Cell Tran

2010
Development of a new radioligand for cholecystokinin receptor subtype 2 scintigraphy: from molecular modeling to in vivo evaluation.
    Bioorganic & medicinal chemistry, 2010, Jul-15, Volume: 18, Issue:14

    Topics: Animals; Chlorocebus aethiops; COS Cells; Humans; Mice; Mice, Nude; Models, Molecular; Neoplasms; NI

2010
Comparative evaluation of glutamate-sensitive radiopharmaceuticals: Technetium-99m-glutamic acid and technetium-99m-diethylenetriaminepentaacetic acid-bis(glutamate) conjugate for tumor imaging.
    Cancer biotherapy & radiopharmaceuticals, 2010, Volume: 25, Issue:6

    Topics: Animal Structures; Animals; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Cell Survival; Cysteine; Dru

2010
Fluorescent and lanthanide labeling for ligand screens, assays, and imaging.
    Methods in molecular biology (Clifton, N.J.), 2011, Volume: 716

    Topics: Animals; Binding Sites; Cell Line; Chelating Agents; Fluorescent Dyes; Heterocyclic Compounds, 1-Rin

2011
Noninvasive imaging of cell death using an Hsp90 ligand.
    Journal of the American Chemical Society, 2011, Mar-09, Volume: 133, Issue:9

    Topics: Animals; Arsenicals; Carbocyanines; Carcinoma, Lewis Lung; Cell Death; Colorectal Neoplasms; HSP90 H

2011
Development of anti-EGF receptor peptidomimetics (AERP) as tumor imaging agent.
    Bioorganic & medicinal chemistry letters, 2011, Apr-15, Volume: 21, Issue:8

    Topics: Animals; Cell Line, Tumor; Enzyme Inhibitors; ErbB Receptors; Humans; Mice; Mice, Nude; Neoplasms; P

2011
Somatostatin receptors as targets for nuclear medicine imaging and radionuclide treatment.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2011, Volume: 52, Issue:6

    Topics: Animals; Drug Delivery Systems; Humans; Neoplasms; Octreotide; Pentetic Acid; Peptides; Positron-Emi

2011
A comparative study of two novel nanosized radiolabeled analogues of methionine for SPECT tumor imaging.
    Current medicinal chemistry, 2013, Volume: 20, Issue:1

    Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Colon; Colonic Neoplasms; Dendrimers; Humans; Methionine;

2013
Tumor targeting of gene expression through metal-coordinated conjugation with dextran.
    Journal of controlled release : official journal of the Controlled Release Society, 2003, Mar-07, Volume: 88, Issue:2

    Topics: Animals; Chelating Agents; Dextrans; DNA; Electrophoresis; Gene Expression Regulation, Neoplastic; G

2003
An intrapatient comparison of 99mTc-EDDA/HYNIC-TOC with 111In-DTPA-octreotide for diagnosis of somatostatin receptor-expressing tumors.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2003, Volume: 44, Issue:5

    Topics: Adult; Aged; Edetic Acid; Female; Humans; Indium Radioisotopes; Male; Middle Aged; Neoplasms; Octreo

2003
PROGRESS REPORT: PLUTONIUM REMOVAL, TUMOR INCIDENCE STUDIES. III. ANL-6723.
    ANL, 1963

    Topics: Bone and Bones; Chelating Agents; Cohort Studies; Metabolism; Mice; Neoplasms; Neoplasms, Experiment

1963
PROGRESS REPORT: PLUTONIUM REMOVAL. TUMOR INCIDENCE STUDIES. V. ANL-6823.
    ANL, 1964

    Topics: Animals; Bone Neoplasms; Chelating Agents; Cohort Studies; Injections, Intravenous; Mice; Neoplasms;

1964
Improved radiolabeling of PEGylated protein: PEGylated annexin V for noninvasive imaging of tumor apoptosis.
    Cancer biotherapy & radiopharmaceuticals, 2003, Volume: 18, Issue:5

    Topics: Animals; Annexin A5; Apoptosis; Cell Line, Tumor; Humans; Neoplasms; Pentetic Acid; Polyethylene Gly

2003
Tumor targeting properties of indium-111 labeled genetically engineered Fab' and F(ab')2 constructs of chimeric tumor necrosis treatment (chTNT)-3 antibody.
    Cancer biotherapy & radiopharmaceuticals, 2003, Volume: 18, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Chelating Agents; Drug Delivery Systems; Genetic Vectors; Immunoglo

2003
A novel antiangiogenesis therapy using an integrin antagonist or anti-Flk-1 antibody coated 90Y-labeled nanoparticles.
    International journal of radiation oncology, biology, physics, 2004, Mar-15, Volume: 58, Issue:4

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Apoptosis; Cell Line, Tumor; Drug Screenin

2004
The role of [(18)F]fluorodeoxyglucose positron emission tomography and [(111)In]-diethylenetriaminepentaacetate-D-Phe-pentetreotide scintigraphy in the localization of ectopic adrenocorticotropin-secreting tumors causing Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:5

    Topics: ACTH Syndrome, Ectopic; Adult; Aged; Cushing Syndrome; Female; Fluorodeoxyglucose F18; Humans; Indiu

2004
Radiolabeled RGD-DTPA-Tyr3-octreotate for receptor-targeted radionuclide therapy.
    Cancer biotherapy & radiopharmaceuticals, 2004, Volume: 19, Issue:2

    Topics: Animals; Cell Line, Tumor; Indium Radioisotopes; Neoplasms; Oligopeptides; Pentetic Acid; Peptides,

2004
Biodistribution data from 100 patients i.v. injected with 111In-DTPA-D-Phe1-octreotide.
    Acta oncologica (Stockholm, Sweden), 2004, Volume: 43, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Indium Radioisotopes; Injections, Intrav

2004
Evaluation of the therapeutic response to In-111-DTPA octreotide-based targeted therapy in liver metastatic neuroendocrine tumors according to CT/MRI/US findings.
    Cancer biotherapy & radiopharmaceuticals, 2005, Volume: 20, Issue:2

    Topics: Adult; Aged; DNA; Female; Humans; Indium; Indium Radioisotopes; Liver; Liver Neoplasms; Magnetic Res

2005
Targeting the tumor-associated folate receptor with an 111In-DTPA conjugate of pteroic acid.
    Journal of the American Chemical Society, 2005, May-25, Volume: 127, Issue:20

    Topics: Animals; Carrier Proteins; Folate Receptors, GPI-Anchored; Humans; Indium Radioisotopes; KB Cells; M

2005
Radioimmunotherapy of solid tumors by targeting extra domain B fibronectin: identification of the best-suited radioimmunoconjugate.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Oct-01, Volume: 11, Issue:19 Pt 2

    Topics: Animals; Bone Marrow; Cell Line, Tumor; Chromatography, High Pressure Liquid; Dimerization; Electrop

2005
Auger electrons: lethal, low energy, and coming soon to a tumor cell nucleus near you.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005, Volume: 46, Issue:12

    Topics: Animals; Cell Nucleus; Electrons; Endocytosis; Humans; Indium Radioisotopes; Neoplasms; Pentetic Aci

2005
Gluc-Lys([18F]FP)-TOCA PET in patients with SSTR-positive tumors: biodistribution and diagnostic evaluation compared with [111In]DTPA-octreotide.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006, Volume: 47, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Female; Fluorine Radioisotopes; Fructose; Humans; Indium Radioisotop

2006
Medicinal chemistry of somatostatin analogs leading to the DTPA and DOTA conjugates of the multi-receptor-ligand SOM230.
    Journal of endocrinological investigation, 2005, Volume: 28, Issue:11 Suppl I

    Topics: Chelating Agents; Heterocyclic Compounds, 1-Ring; Humans; Hydroxyproline; Isotope Labeling; Neoplasm

2005
Preparation of PEG-conjugated fullerene containing Gd3+ ions for photodynamic therapy.
    Journal of controlled release : official journal of the Controlled Release Society, 2007, Jan-22, Volume: 117, Issue:1

    Topics: Animals; Cell Line, Tumor; Chelating Agents; Cobalt Radioisotopes; Contrast Media; Excipients; Fulle

2007
111Indium-trastuzumab visualises myocardial human epidermal growth factor receptor 2 expression shortly after anthracycline treatment but not during heart failure: a clue to uncover the mechanisms of trastuzumab-related cardiotoxicity.
    European journal of cancer (Oxford, England : 1990), 2007, Volume: 43, Issue:14

    Topics: Adult; Aged; Anthracyclines; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplast

2007
Paramagnetic pharmaceuticals for magnetic resonance imaging.
    Physiological chemistry and physics and medical NMR, 1984, Volume: 16, Issue:2

    Topics: Abdomen; Adult; Animals; Brain; Contrast Media; Deferoxamine; Electron Spin Resonance Spectroscopy;

1984
The use of iron and gadolinium chelates as NMR contrast agents: animal and human studies.
    Physiological chemistry and physics and medical NMR, 1984, Volume: 16, Issue:2

    Topics: Abdominal Neoplasms; Animals; Brain Neoplasms; Colonic Neoplasms; Contrast Media; Edetic Acid; Ferri

1984
[Survey on adverse reactions to radiopharmaceuticals: Report No. 3 (the 6th survey in 1980)].
    Kaku igaku. The Japanese journal of nuclear medicine, 1982, Volume: 19, Issue:7

    Topics: Adolescent; Adosterol; Adrenal Glands; Adult; Aged; Child; Female; Gallium Radioisotopes; Hippurates

1982
Magnetic resonance imaging of the lacrimal drainage system.
    Ophthalmology, 1994, Volume: 101, Issue:2

    Topics: Abscess; Adult; Aged; Aged, 80 and over; Child; Female; Gadolinium DTPA; Humans; Lacrimal Apparatus;

1994
A distributed pharmacokinetic model of two-step imaging and treatment protocols: application to streptavidin-conjugated monoclonal antibodies and radiolabeled biotin.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1993, Volume: 34, Issue:9

    Topics: Bacterial Proteins; Biotin; Humans; Indium Radioisotopes; Models, Theoretical; Neoplasms; Pentetic A

1993
Distribution and elimination of the somatostatin analogue (111In-DTPA-D-Phe1)-Octreotide (OctreoScan111).
    Acta oncologica (Stockholm, Sweden), 1993, Volume: 32, Issue:2

    Topics: Adenoma, Islet Cell; Adult; Aged; Carcinoid Tumor; Chromatography, Gel; Endocrine Gland Neoplasms; F

1993
In vitro and in vivo studies of three radiolabelled somatostatin analogues: 123I-octreotide (OCT), 123I-Tyr-3-OCT and 111In-DTPA-D-Phe-1-OCT.
    European journal of nuclear medicine, 1996, Volume: 23, Issue:10

    Topics: Adolescent; Adult; Aged; Carcinoid Tumor; Female; Humans; In Vitro Techniques; Indium Radioisotopes;

1996
Carboplatin dosing based on measurement of renal function--experience at the Peter MacCallum Cancer Institute.
    Australian and New Zealand journal of medicine, 1996, Volume: 26, Issue:3

    Topics: Antineoplastic Agents; Area Under Curve; Carboplatin; Chromium Radioisotopes; Female; Glomerular Fil

1996
Unsulfated DTPA- and DOTA-CCK analogs as specific high-affinity ligands for CCK-B receptor-expressing human and rat tissues in vitro and in vivo.
    European journal of nuclear medicine, 1998, Volume: 25, Issue:5

    Topics: Animals; Autoradiography; Cholecystokinin; Female; Humans; Indium Radioisotopes; Neoplasms; Pentetic

1998
Experiences with high dose radiopeptide therapy: the health physics perspective.
    Health physics, 1999, Volume: 76, Issue:3

    Topics: Aged; Female; Guidelines as Topic; Half-Life; Health Physics; Humans; Indium Radioisotopes; Iodine R

1999
Enhanced MRI fills in soft tissue features.
    Diagnostic imaging, 1991, Volume: 13, Issue:5

    Topics: Contrast Media; Follow-Up Studies; Gadolinium; Humans; Magnetic Resonance Imaging; Neoplasms; Pentet

1991
Evaluation of three gamma detectors for intraoperative detection of tumors using 111In-labeled radiopharmaceuticals.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1999, Volume: 40, Issue:12

    Topics: Cadmium Compounds; Cesium; Evaluation Studies as Topic; Gamma Rays; Humans; Indium Radioisotopes; In

1999
Comparison between transversal SPECT, 3-dimensional rendering and 3-dimensional rendering plus clipping in the diagnosis of somatostatin receptor distribution in malignancies using 111In-DTPA-D-Phe1-octreotide scintigraphy.
    Cancer biotherapy & radiopharmaceuticals, 1997, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Neoplasms; Octreotide

1997
Evaluation of a radiolabelled cyclic DTPA-RGD analogue for tumour imaging and radionuclide therapy.
    International journal of cancer, 2000, Aug-20, Volume: 90, Issue:4

    Topics: Animals; Antineoplastic Agents; Autoradiography; Chromatography, High Pressure Liquid; Humans; Immun

2000
Single-cell cytotoxicity with radiolabeled antibodies.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:1

    Topics: Antibodies, Monoclonal; Antigen-Antibody Complex; Antigens, Differentiation, B-Lymphocyte; Cytotoxic

2001
Stealth liposomes and tumor targeting: one step further in the quest for the magic bullet.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:2

    Topics: Drug Delivery Systems; Humans; Indium Radioisotopes; Liposomes; Neoplasms; Pentetic Acid; Radionucli

2001
Effective targeting of solid tumors in patients with locally advanced cancers by radiolabeled pegylated liposomes.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:2

    Topics: Adult; Aged; Drug Carriers; Drug Delivery Systems; Drug Stability; Female; Humans; Indium Radioisoto

2001
Intraoperative tumour detection using 111In-DTPA-D-Phe1-octreotide and a scintillation detector.
    European journal of nuclear medicine, 2001, Volume: 28, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Intraoperative Care; Male; Middle Aged;

2001
Influence of inhaled Ca-DTPA on the long-term effects of inhaled Pu nitrate.
    Health physics, 1977, Volume: 32, Issue:6

    Topics: Aerosols; Animals; Body Weight; Bone Neoplasms; Calcium; Dose-Response Relationship, Drug; Dose-Resp

1977
Somatostatin receptor scintigraphy with indium-111-DTPA-D-Phe-1-octreotide in man: metabolism, dosimetry and comparison with iodine-123-Tyr-3-octreotide.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1992, Volume: 33, Issue:5

    Topics: Adult; Aged; Female; Humans; Indium Radioisotopes; Iodine Radioisotopes; Male; Middle Aged; Neoplasm

1992
[Potential application of DTPA for improving the image quality in radioimmunoscintigraphy with 111In labeled monoclonal antibodies].
    Kaku igaku. The Japanese journal of nuclear medicine, 1992, Volume: 29, Issue:1

    Topics: Animals; Indium Radioisotopes; Liver; Male; Neoplasms; Pentetic Acid; Protein Binding; Radioimmunode

1992
[111In-DTPA-D-Phe1]-octreotide, a potential radiopharmaceutical for imaging of somatostatin receptor-positive tumors: synthesis, radiolabeling and in vitro validation.
    Life sciences, 1991, Volume: 49, Issue:22

    Topics: Amino Acid Sequence; Animals; Female; In Vitro Techniques; Indium Radioisotopes; Isotope Labeling; M

1991
Favorable results in cancer imaging and therapy using monoclonal antibodies.
    Oncology (Williston Park, N.Y.), 1991, Volume: 5, Issue:7

    Topics: Antibodies, Monoclonal; Humans; Neoplasms; Oligopeptides; Pentetic Acid; Radioisotopes; Radionuclide

1991
[Contrasts in the FLASH sequences in the study of musculoskeletal tumors: phantom study and theoretical calculations].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1991, Volume: 154, Issue:5

    Topics: Bone Neoplasms; Contrast Media; Gadolinium; Gadolinium DTPA; Humans; Magnetic Resonance Imaging; Mod

1991
Carbohydrate-derivatized immunoconjugate of the anti-(carcinoembryonic antigen) monoclonal antibody C46: immunohistological reactivity and pharmacokinetic comparison with a randomly derivatized C46 immunoconjugate.
    Cancer immunology, immunotherapy : CII, 1990, Volume: 32, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Carbohydrates; Carcinoembryonic Antigen; Dose

1990
Musculoskeletal neoplasms: dynamic Gd-DTPA-enhanced MR imaging.
    Radiology, 1990, Volume: 177, Issue:1

    Topics: Bone Neoplasms; Contrast Media; Gadolinium DTPA; Humans; Magnetic Resonance Imaging; Muscular Diseas

1990
The radionuclide assessment of a system for slow intrathecal infusion of drugs.
    Clinical nuclear medicine, 1989, Volume: 14, Issue:4

    Topics: Aged; Analgesics, Opioid; Equipment Failure; Evaluation Studies as Topic; Humans; Infusion Pumps; In

1989
[Gadolinium-DTPA in magnetic resonance tomography. Clinical use--indications].
    Rontgen-Blatter; Zeitschrift fur Rontgen-Technik und medizinisch-wissenschaftliche Photographie, 1989, Volume: 42, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bone Neoplasms; Brain Neoplasms; Child; Contrast Media;

1989
[Clinical studies of radionuclide angiography with a new radioactive tracer, 99mTc-DTPA-human serum albumin].
    Kaku igaku. The Japanese journal of nuclear medicine, 1988, Volume: 25, Issue:11

    Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Neoplasms; Organometallic Compounds; Pentetic Acid;

1988
Significance of skeletal uptake detected on radionuclide renal perfusion studies.
    Clinical nuclear medicine, 1987, Volume: 12, Issue:6

    Topics: Bone and Bones; Bone Diseases; Bone Marrow; Humans; Kidney Diseases; Male; Middle Aged; Neoplasms; O

1987
[Immunoscintigraphy using 111In-DTPA-labeled monoclonal antibodies: comparison with ECT and planar scintigraphy].
    Nuklearmedizin. Nuclear medicine, 1987, Volume: 26, Issue:6

    Topics: Adult; Aged; Antibodies, Monoclonal; Humans; Middle Aged; Neoplasms; Pentetic Acid; Radionuclide Ima

1987
Radiolabeled biomolecules with 186Re: potential for radioimmunotherapy.
    International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1986, Volume: 13, Issue:4

    Topics: Antibodies, Monoclonal; Humans; Indicators and Reagents; Neoplasms; Pentetic Acid; Radioisotopes; Rh

1986
Pharmacokinetics of an indium-111-labeled monoclonal antibody in cancer patients.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1985, Volume: 26, Issue:8

    Topics: Adult; Aged; Antibodies, Monoclonal; Antigen-Antibody Complex; Antigens, Neoplasm; Antigens, Tumor-A

1985
Phase I study of the cisplatin analogue 1,1-diamminomethylcyclohexane sulfatoplatinum (TNO-6) (NSC 311056).
    Cancer chemotherapy and pharmacology, 1985, Volume: 15, Issue:2

    Topics: Adult; Aged; Drug Evaluation; Female; Humans; Iodohippuric Acid; Kidney Tubules; Leukopenia; Male; M

1985
Plutonium ( 239 Pu) toxicity diagnosis and therapy.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1972, Volume: 14, Issue:1

    Topics: Accidents, Occupational; Animals; Chemical Phenomena; Chemistry; Dogs; Environmental Exposure; Feces

1972