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pentetic acid and Neoplasm Metastasis

pentetic acid has been researched along with Neoplasm Metastasis in 32 studies

Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
"Metastasis is the principal cause of death in breast cancer patients."5.31In vitro cytotoxicity of bismuth-213 (213Bi)-labeled-plasminogen activator inhibitor type 2 (alpha-PAI-2) on human breast cancer cells. ( Allen, BJ; Andronicos, NM; Ranson, M; Rizvi, S; Tian, Z, 2002)
"Thirteen (13) patients with liver neuroendocrine carcinomas metastases, positive for somatostatin receptors, confirmed by scintigraphy were infused with 4070-7030 MBq per session of In-111-octreotide after selective hepatic catheterization, exploiting the catastrophic activity of Indium Auger and Internal Conversion electron emission on cell DNA."3.73Evaluation of the therapeutic response to In-111-DTPA octreotide-based targeted therapy in liver metastatic neuroendocrine tumors according to CT/MRI/US findings. ( Dimitriou, P; Dimitropoulos, N; Hatzioannou, A; Kontogeorgakos, D; Koutoulidis, V; Limouris, GS; Lyra, M; Mourikis, D; Papanikolos, G; Stravaka, A; Vlahos, L, 2005)
"Patients with human epidermal growth factor receptor 2 (HER2) -positive metastatic breast cancer underwent gamma camera imaging from 15 minutes to 7 days after injection of 150 MBq 111In-diethylenetriamine penta-acetic acid anhydride (DTPA) -trastuzumab, after loading-dose trastuzumab, and after once-a-week trastuzumab doses for 11 weeks, and concomitant paclitaxel once every 3 weeks."3.73Indium-111-labeled trastuzumab scintigraphy in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer. ( de Korte, MA; de Vries, EG; Gietema, JA; Jager, PL; Jonkman, S; Kosterink, JG; Lub-De Hooge, MN; Perik, PJ; Sleijfer, DT; van der Graaf, WT; van Veldhuisen, DJ, 2006)
"Observation of responses without any toxicity indicates that targeted alpha therapy has the potential to be a safe and effective therapeutic approach for metastatic melanoma."2.73Interim analysis of toxicity and response in phase 1 trial of systemic targeted alpha therapy for metastatic melanoma. ( Abbas Rizvi, SM; Allen, BJ; Apostolidis, C; Bosserhoff, A; Goldsmith, H; Graham, P; Kearsley, J; Morgenstern, A; Raja, C; Reisfeld, R; Song, E; Thompson, J, 2007)
"In one patient with widespread bone metastases, octreotide gave a more detailed assessment of metastatic disease than conventional radiology."2.71Indium-111-labelled octreotide scintigraphy in the diagnosis and management of non-iodine avid metastatic carcinoma of the thyroid. ( Christian, JA; Cook, GJ; Harmer, C, 2003)
"Metastasis is the principal cause of death in breast cancer patients."1.31In vitro cytotoxicity of bismuth-213 (213Bi)-labeled-plasminogen activator inhibitor type 2 (alpha-PAI-2) on human breast cancer cells. ( Allen, BJ; Andronicos, NM; Ranson, M; Rizvi, S; Tian, Z, 2002)
"In order to detect recurrences or metastases, in conjunction with conventional imaging techniques (cervical and hepatic ultrasonography, lung CT scan."1.30[Value of scintigraphic explorations by radiomarkers others than iodine radioisotope in differentiated thyroid cancer]. ( Borson-Chazot, F; Houzard, C; Sassolas, G; Sigartau, C, 1997)
"The development of hepatic metastases was determined 21 days after direct injection of SS-R-positive or -negative tumour cells into the vena porta in rats."1.30Anti-proliferative effect of radiolabelled octreotide in a metastases model in rat liver. ( Breeman, WA; Krenning, EP; Marquet, RL; Slooter, GD; van Eijck, CH, 1999)
"Dynamic MR image series were analyzed with a pharmacokinetic two-compartment model."1.29Pelvic lesions in patients with treated cervical carcinoma: efficacy of pharmacokinetic analysis of dynamic MR images in distinguishing recurrent tumors from benign conditions. ( Brix, G; Essig, M; Hawighorst, H; Hoffmann, U; Knapstein, PG; Knopp, MV; Schaeffer, U; van Kaick, G; Zuna, I, 1996)
"Immune-deprived mice bearing HX99 human breast carcinoma xenografts were injected with a radiolabelled monoclonal antibody, LICR-LON-M8 (M8), to investigate the dependence of tumour localization on (i) tumour site and (ii) antibody radiolabel."1.27The localization of human breast carcinomas by radiolabelled monoclonal antibodies. ( Rainsbury, RM, 1984)
"A case of cerebral metastases is presented in which the initial brain scan did not demonstrate the lesion because steroid medication had been started 18 hr earlier."1.25Steroid effect on the brain scan in a patient with cerebral metastases. ( Stebner, FC, 1975)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19909 (28.13)18.7374
1990's9 (28.13)18.2507
2000's11 (34.38)29.6817
2010's3 (9.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pfeifer, A1
Knigge, U1
Binderup, T1
Mortensen, J1
Oturai, P1
Loft, A1
Berthelsen, AK1
Langer, SW1
Rasmussen, P1
Elema, D1
von Benzon, E1
Højgaard, L1
Kjaer, A1
Namwongprom, S1
Wong, FC1
Tateishi, U1
Kim, EE1
Boonyaprapa, S1
Lingappa, M1
Song, H1
Thompson, S1
Bruchertseifer, F1
Morgenstern, A3
Sgouros, G1
Salaun, PY1
Campion, L1
Bournaud, C1
Faivre-Chauvet, A1
Vuillez, JP1
Taieb, D1
Ansquer, C1
Rousseau, C1
Borson-Chazot, F2
Bardet, S1
Oudoux, A1
Cariou, B1
Mirallié, E1
Chang, CH1
Sharkey, RM1
Goldenberg, DM1
Chatal, JF1
Barbet, J1
Kraeber-Bodéré, F1
Christian, JA1
Cook, GJ1
Harmer, C1
El-Mabhouh, A1
Angelov, C1
McEwan, A1
Jia, G1
Mercer, J1
Limouris, GS1
Dimitropoulos, N1
Kontogeorgakos, D1
Papanikolos, G1
Koutoulidis, V1
Hatzioannou, A1
Mourikis, D1
Lyra, M1
Dimitriou, P1
Stravaka, A1
Vlahos, L1
Abbas Rizvi, SM2
Li, Y1
Song, EY1
Qu, CF1
Raja, C2
Apostolidis, C2
Allen, BJ3
Tolmachev, V1
Nilsson, FY1
Widström, C1
Andersson, K1
Rosik, D1
Gedda, L1
Wennborg, A1
Orlova, A1
Perik, PJ1
Lub-De Hooge, MN1
Gietema, JA1
van der Graaf, WT1
de Korte, MA1
Jonkman, S1
Kosterink, JG1
van Veldhuisen, DJ1
Sleijfer, DT1
Jager, PL1
de Vries, EG1
Graham, P1
Song, E1
Goldsmith, H1
Thompson, J1
Bosserhoff, A1
Kearsley, J1
Reisfeld, R1
Rainsbury, RM1
Tenenbaum, F1
Lumbroso, J2
Schlumberger, M1
Mure, A1
Plouin, PF1
Caillou, B1
Parmentier, C1
Krenning, EP3
Kwekkeboom, DJ2
Oei, HY2
de Jong, RJ1
Dop, FJ1
Reubi, JC2
Lamberts, SW1
Kramer, EL1
DeNardo, SJ1
Liebes, L1
Kroger, LA1
Noz, ME1
Mizrachi, H1
Salako, QA1
Furmanski, P1
Glenn, SD1
DeNardo, GL1
Joseph, K1
Stapp, J1
Reinecke, J1
Skamel, HJ1
Höffken, H1
Neuhaus, C1
Lenze, H1
Trautmann, ME1
Arnold, R1
Hawighorst, H1
Knapstein, PG1
Schaeffer, U1
Knopp, MV1
Brix, G1
Hoffmann, U1
Zuna, I1
Essig, M1
van Kaick, G1
Postema, PT1
De Herder, WW1
Bruining, HJ1
Bonjer, J1
van Toor, H1
Hennemann, G1
Sassolas, G1
Houzard, C1
Sigartau, C1
Slooter, GD1
Breeman, WA1
Marquet, RL1
van Eijck, CH1
Banzo, J1
Abós, MD1
Prats, E1
García, F1
Razola, P1
Raderer, M1
Traub, T1
Formanek, M1
Virgolini, I1
Osterreicher, C1
Fiebiger, W1
Penz, M1
Jäger, U1
Pont, J1
Chott, A1
Kurtaran, A1
Ranson, M1
Tian, Z1
Andronicos, NM1
Rizvi, S1
Stebner, FC1
Silberstein, EB1
Calatayud-Maldonado, V1
Banzo-Marraco, J1
Uriguen-Saiz, M1
Teijeiro-Vidal, J1
Gonzalez-Arias, S1
Carreras, JL1
Redondo-Marco, J1
Moreau, R1
Doerr, RJ1
Abdel-Nabi, HH1
Constantinovici, A1
Wolfstein, RS1
Tanasescu, D1
Sakimura, IT1
Waxman, AD1
Siemsen, JK1
Jansen, CR1
Meyer, BJ1
Bieler, EU1
du Toit, D1
Brookeman, VA1
Williams, CM1

Reviews

3 reviews available for pentetic acid and Neoplasm Metastasis

ArticleYear
Somatostatin-receptor scintigraphy in gastroenteropancreatic tumors. An overview of European results.
    Annals of the New York Academy of Sciences, 1994, Sep-15, Volume: 733

    Topics: Europe; Humans; Indium Radioisotopes; Neoplasm Metastasis; Neuroendocrine Tumors; Octreotide; Pancre

1994
[Scintigraphy of somatostatin receptors in the diagnosis and staging of neuroendocrine tumors of the digestive tract and pancreas].
    Revista espanola de medicina nuclear, 2000, Volume: 19, Issue:3

    Topics: Algorithms; Animals; Binding, Competitive; Biomarkers, Tumor; Clinical Trials, Phase I as Topic; Gas

2000
OncoScint CR103 imaging in the surgical management of patients with colorectal cancer.
    Targeted diagnosis and therapy, 1992, Volume: 6

    Topics: Antibodies, Monoclonal; Colorectal Neoplasms; Female; Humans; Indium Radioisotopes; Male; Neoplasm M

1992

Trials

7 trials available for pentetic acid and Neoplasm Metastasis

ArticleYear
Phase II trial of anticarcinoembryonic antigen pretargeted radioimmunotherapy in progressive metastatic medullary thyroid carcinoma: biomarker response and survival improvement.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2012, Volume: 53, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antibodies, Bispecific; Antibodies, Monoclonal, Humanized;

2012
Indium-111-labelled octreotide scintigraphy in the diagnosis and management of non-iodine avid metastatic carcinoma of the thyroid.
    British journal of cancer, 2003, Jul-21, Volume: 89, Issue:2

    Topics: Antineoplastic Agents, Hormonal; Bone Neoplasms; Chelating Agents; Humans; Indium Radioisotopes; Iod

2003
Interim analysis of toxicity and response in phase 1 trial of systemic targeted alpha therapy for metastatic melanoma.
    Cancer biology & therapy, 2007, Volume: 6, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Agents; Biomarkers, Tumor; Co

2007
Radioimmunolocalization of metastatic breast carcinoma using indium-111-methyl benzyl DTPA BrE-3 monoclonal antibody: phase I study.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1993, Volume: 34, Issue:7

    Topics: Breast Neoplasms; Chelating Agents; Female; Humans; Indium Radioisotopes; Middle Aged; Neoplasm Meta

1993
Somatostatin receptor scintigraphy in non-medullary thyroid cancer.
    Digestion, 1996, Volume: 57 Suppl 1

    Topics: Carcinoma, Papillary; Carcinoma, Papillary, Follicular; Humans; Indium Radioisotopes; Neoplasm Metas

1996
Somatostatin-receptor scintigraphy for staging and follow-up of patients with extraintestinal marginal zone B-cell lymphoma of the mucosa associated lymphoid tissue (MALT)-type.
    British journal of cancer, 2001, Nov-16, Volume: 85, Issue:10

    Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Lymph Nodes; Lymphatic Metastasis; Lymphoma, B-Cell,

2001
Brain scintigraphy in the diagnosis of intracranial lesions. Comparative scanning with 169 ytterbium diethylenetriaminepenta-acetic acid and 203 mercury chlormerodrin.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Feb-10, Volume: 47, Issue:6

    Topics: Brain Diseases; Brain Neoplasms; Cerebral Angiography; Chlormerodrin; Costs and Cost Analysis; Drug

1973

Other Studies

22 other studies available for pentetic acid and Neoplasm Metastasis

ArticleYear
64Cu-DOTATATE PET for Neuroendocrine Tumors: A Prospective Head-to-Head Comparison with 111In-DTPA-Octreotide in 112 Patients.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2015, Volume: 56, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Biopsy; Female; Humans; Image Processing, Computer-Assisted; Male; M

2015
Correlation of chromogranin A levels and somatostatin receptor scintigraphy findings in the evaluation of metastases in carcinoid tumors.
    Annals of nuclear medicine, 2008, Volume: 22, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Carcinoid Tumor; Chromogranin A

2008
Immunoliposomal delivery of 213Bi for alpha-emitter targeting of metastatic breast cancer.
    Cancer research, 2010, Sep-01, Volume: 70, Issue:17

    Topics: Alpha Particles; Animals; Bismuth; Female; Immunoconjugates; Isothiocyanates; Liposomes; Mammary Neo

2010
Preclinical investigations of drug and radionuclide conjugates of bisphosphonates for the treatment of metastatic bone cancer.
    Cancer biotherapy & radiopharmaceuticals, 2004, Volume: 19, Issue:5

    Topics: Animals; Antimetabolites, Antineoplastic; Bone Neoplasms; Diphosphonates; Female; Fluorouracil; Huma

2004
Evaluation of the therapeutic response to In-111-DTPA octreotide-based targeted therapy in liver metastatic neuroendocrine tumors according to CT/MRI/US findings.
    Cancer biotherapy & radiopharmaceuticals, 2005, Volume: 20, Issue:2

    Topics: Adult; Aged; DNA; Female; Humans; Indium; Indium Radioisotopes; Liver; Liver Neoplasms; Magnetic Res

2005
Preclinical studies of bismuth-213 labeled plasminogen activator inhibitor type 2 (PAI2) in a prostate cancer nude mouse xenograft model.
    Cancer biology & therapy, 2006, Volume: 5, Issue:4

    Topics: Animals; Bismuth; Chelating Agents; Cycloheximide; Humans; Male; Mice; Mice, Nude; Neoplasm Metastas

2006
111In-benzyl-DTPA-ZHER2:342, an affibody-based conjugate for in vivo imaging of HER2 expression in malignant tumors.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006, Volume: 47, Issue:5

    Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Female; Humans; Indium Radioisotopes; Mice; Mice, In

2006
Indium-111-labeled trastuzumab scintigraphy in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, May-20, Volume: 24, Issue:15

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2006
The localization of human breast carcinomas by radiolabelled monoclonal antibodies.
    The British journal of surgery, 1984, Volume: 71, Issue:10

    Topics: Animals; Antibodies, Monoclonal; Breast Neoplasms; Diphosphonates; Evaluation Studies as Topic; Fema

1984
Comparison of radiolabeled octreotide and meta-iodobenzylguanidine (MIBG) scintigraphy in malignant pheochromocytoma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1995, Volume: 36, Issue:1

    Topics: 3-Iodobenzylguanidine; Adrenal Gland Neoplasms; Adult; Aged; Female; Ganglioneuroblastoma; Humans; I

1995
Receptor scintigraphy with 111In-pentetreotide for endocrine gastroenteropancreatic tumors.
    Hormone and metabolic research. Supplement series, 1993, Volume: 27

    Topics: Aged; Carcinoid Tumor; Gastrinoma; Gastrointestinal Neoplasms; Humans; Indium Radioisotopes; Insulin

1993
Pelvic lesions in patients with treated cervical carcinoma: efficacy of pharmacokinetic analysis of dynamic MR images in distinguishing recurrent tumors from benign conditions.
    AJR. American journal of roentgenology, 1996, Volume: 166, Issue:2

    Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Contrast Media; Diagnosis, Differential; Drug C

1996
[Value of scintigraphic explorations by radiomarkers others than iodine radioisotope in differentiated thyroid cancer].
    Annales d'endocrinologie, 1997, Volume: 58, Issue:1

    Topics: Adenocarcinoma; Carcinoma, Papillary; Deoxyglucose; Fluorodeoxyglucose F18; Humans; Iodine Radioisot

1997
Anti-proliferative effect of radiolabelled octreotide in a metastases model in rat liver.
    International journal of cancer, 1999, May-31, Volume: 81, Issue:5

    Topics: Animals; Drug Administration Schedule; Indium Radioisotopes; Liver Neoplasms, Experimental; Male; Ne

1999
In vitro cytotoxicity of bismuth-213 (213Bi)-labeled-plasminogen activator inhibitor type 2 (alpha-PAI-2) on human breast cancer cells.
    Breast cancer research and treatment, 2002, Volume: 71, Issue:2

    Topics: Bismuth; Breast Neoplasms; Cell Survival; Female; Humans; Kinetics; Neoplasm Metastasis; Pentetic Ac

2002
Steroid effect on the brain scan in a patient with cerebral metastases.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1975, Volume: 16, Issue:4

    Topics: Adult; Brain Neoplasms; Dexamethasone; Humans; Male; Neoplasm Metastasis; Pentetic Acid; Radionuclid

1975
Optimizing brain-scan sensitivity.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1978, Volume: 19, Issue:5

    Topics: Brain Diseases; Brain Neoplasms; Cerebrovascular Disorders; Evaluation Studies as Topic; Humans; Neo

1978
Diagnosis of intracranial space-occupying lesions with DTPA-Sn-99mTc.
    Acta neurochirurgica, 1978, Volume: 41, Issue:4

    Topics: Brain Neoplasms; Humans; Meningioma; Neoplasm Metastasis; Pentetic Acid; Radionuclide Imaging; Techn

1978
[Gamma-myelography in neurosurgery].
    Neuro-Chirurgie, 1976, Volume: 22, Issue:4

    Topics: Brain Diseases; Emergencies; Humans; Neoplasm Metastasis; Pentetic Acid; Radionuclide Imaging; Spina

1976
Cerebral scintiphotos with 113mIn.
    Acta radiologica: diagnosis, 1972, Volume: 13, Issue:0

    Topics: Brain Diseases; Brain Neoplasms; Diagnosis, Differential; Diagnostic Errors; Edetic Acid; Glioblasto

1972
Brain imaging with 99mTc-DTPA: a clinical comparison of early and delayed studies.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1974, Volume: 15, Issue:12

    Topics: Aged; Arteriovenous Malformations; Brain; Brain Diseases; Brain Neoplasms; Cerebrovascular Disorders

1974
Evaluation of 99mTc-DTPA acid as a brain scanning agent.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1970, Volume: 11, Issue:12

    Topics: Astrocytoma; Brain; Brain Diseases; Brain Neoplasms; Humans; Ischemic Attack, Transient; Meningioma;

1970