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pentetic acid and Malignant Melanoma

pentetic acid has been researched along with Malignant Melanoma in 44 studies

Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.

Research Excerpts

ExcerptRelevanceReference
"Choroidal melanoma is the most common intraocular tumor and is uniquely suited for evaluation by magnetic resonance imaging (MRI) because of the paramagnetic effect of the melanin molecule."5.28Magnetic resonance imaging of choroidal melanoma with and without gadolinium contrast enhancement. ( Bond, JB; Gupta, KL; Haik, BG; Mihara, F, 1991)
" Malignant melanomas could not be differentiated from benign melanocytic nevi with the use of gadopentetate dimeglumine."3.69Failure of gadopentetate dimeglumine-enhanced, high-resolution magnetic resonance imaging to differentiate among melanin-containing skin tumors. ( Bier, J; Felix, R; Garbe, C; Knollmann, FD; Mäurer, J; Schlums, D; Vogl, TJ, 1996)
"A phase 1 study was conducted using a monoclonal antimelanoma antibody-DTPA conjugate labeled with indium-111, for immunolymphoscintigraphy in patients with metastatic melanoma."3.67Phase 1 immunolymphoscintigraphy with an In-111-labeled antimelanoma monoclonal antibody. ( Corpuz, SW; Del Rio, MJ; Engelstad, BL; Huberty, JP; Khentigan, A; Lee, HM; Ramos, EC; Reinhold, CE; Rosendorf, LL; Spitler, LE, 1986)
"Observation of responses without any toxicity indicates that targeted alpha therapy has the potential to be a safe and effective therapeutic approach for metastatic melanoma."2.73Interim analysis of toxicity and response in phase 1 trial of systemic targeted alpha therapy for metastatic melanoma. ( Abbas Rizvi, SM; Allen, BJ; Apostolidis, C; Bosserhoff, A; Goldsmith, H; Graham, P; Kearsley, J; Morgenstern, A; Raja, C; Reisfeld, R; Song, E; Thompson, J, 2007)
"Melanoma is a highly malignant skin cancer that frequently metastasizes to the lung, bone, and brain at an early phase."1.62A Radiolabeled Self-assembled Nanoparticle Probe for Diagnosis of Lung-Metastatic Melanoma. ( Mukai, T; Munekane, M; Sano, K; Sasaki, H; Tanaka, T; Yamasaki, T, 2021)
"Twenty-seven melanocytic nevi and 18 malignant melanomas were examined by high resolution MRI."1.29Role of high-resolution magnetic resonance imaging for differentiating melanin-containing skin tumors. ( Bier, J; Felix, R; Garbe, C; Knollmann, FD; Mäurer, J; Schlums, D; Vogl, TJ, 1995)
"Cubic volumes containing brain metastases of lung cancer (n = 17), mammary carcinoma (n = 24), melanoma (n = 12) and those originating from other tumors (n = 13) were examined using the double spin echo technique with CHESS pulses for water suppression and TE = 135 ms."1.291H MR spectroscopy detection of lipids and lactate in metastatic brain tumors. ( Levendag, PC; Oudkerk, M; Sijens, PE; van Dijk, P; Vecht, CJ, 1996)
" The pilot clinical study of the 99mTc labelled anti melanoma Fab and 111-In-DTPA labelled anti melanoma F(ab')2 showed differences in the pharmacokinetic parameters."1.28Pharmacokinetics of radiopharmaceuticals. ( Jánoki, GA; Kerekes, A, 1992)
"Choroidal melanoma is the most common intraocular tumor and is uniquely suited for evaluation by magnetic resonance imaging (MRI) because of the paramagnetic effect of the melanin molecule."1.28Magnetic resonance imaging of choroidal melanoma with and without gadolinium contrast enhancement. ( Bond, JB; Gupta, KL; Haik, BG; Mihara, F, 1991)
"Immunoscintigraphic and pharmacokinetic characteristics of 111In-labeled ZME-018 monoclonal antibody were examined in 8 patients with malignant melanoma."1.27Immunoscintigraphy and pharmacokinetics of indium-111-labeled ZME-018 monoclonal antibody in patients with malignant melanoma. ( Arano, Y; Endo, K; Imamura, S; Kashihara-Sawami, M; Koizumi, M; Konishi, J; Miyachi, Y; Saga, T; Sakahara, H; Watanabe, Y, 1988)
" Changes in relaxation times in normal and abnormal tissues following contrast medium, toxicity and dosage of gadolinium-DTPA, and MRI pulse sequence techniques are reviewed."1.27Contrast-enhanced magnetic resonance imaging of tumours of the central nervous system: a clinical review. ( Graif, M; Steiner, RE, 1986)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19909 (20.45)18.7374
1990's24 (54.55)18.2507
2000's7 (15.91)29.6817
2010's3 (6.82)24.3611
2020's1 (2.27)2.80

Authors

AuthorsStudies
Tanaka, T1
Sano, K1
Munekane, M1
Yamasaki, T1
Sasaki, H1
Mukai, T1
Kameswaran, M1
Pandey, U1
Sarma, HD1
Samuel, G1
Leong, SP1
Kim, J1
Ross, M1
Faries, M1
Scoggins, CR1
Metz, WL1
Cope, FO1
Orahood, RC1
Gada, KS1
Patil, V1
Panwar, R1
Majewski, S1
Tekabe, Y1
Khaw, BA1
Wang, W2
McMurray, JS1
Wu, Q2
Campbell, ML1
Li, C3
Ke, S1
Houston, J1
Sevick-Muraca, E1
Dong, L1
Chow, D1
Charnsangavej, C1
Gelovani, JG1
Raja, C1
Graham, P1
Abbas Rizvi, SM2
Song, E1
Goldsmith, H1
Thompson, J1
Bosserhoff, A1
Morgenstern, A1
Apostolidis, C1
Kearsley, J1
Reisfeld, R1
Allen, BJ2
Wang, TS3
Srivastava, SC2
Fawwaz, RA3
Giacomini, P1
Ferrone, S2
Richards, P2
Hardy, M1
Alderson, PO3
Dewulf, P1
Demaerel, P1
Wilms, G1
Delanote, G1
Defloor, E1
Casselman, J1
Baert, AL1
Lundby, B1
Berg, KJ1
Lien, HH1
Aamdal, S1
Bard, DR3
Wraight, EP2
Knight, CG3
Mäurer, J2
Knollmann, FD2
Schlums, D2
Garbe, C2
Vogl, TJ2
Bier, J2
Felix, R3
Mitchell, DG1
Stolpen, AH1
Siegelman, ES1
Bolinger, L1
Outwater, EK1
Sijens, PE1
Levendag, PC1
Vecht, CJ1
van Dijk, P1
Oudkerk, M1
Yousem, DM1
Montone, KT1
Montgomery, L1
Loevner, LA1
Rao, V1
Chung, TS1
Kimura, Y1
Hayden, RE1
Weinstein, GS1
Sciuto, R1
Ferraironi, A1
Semprebene, A1
Occhipinti, E1
Mastrostefano, R1
Crecco, M1
Mottolese, M1
Maini, CL1
Crasto, S1
Duca, S1
Davini, O1
Rizzo, L1
Pavanello, IG1
Avataneo, T1
Cirillo, S1
Regge, D1
Soffietti, R1
Hosten, N2
Lemke, AJ1
Heinig, A1
Heywang-Köbrunner, SH1
Wohlrab, J1
Sarkar, S1
Goozee, G1
Reilly, RM1
Maiti, PK1
Kiarash, R1
Prashar, AK1
Fast, DG1
Entwistle, J1
Narang, SA1
Foote, S1
Kaplan, HA1
Lee, FT1
Rigopoulos, A1
Hall, C1
Clarke, K1
Cody, SH1
Smyth, FE1
Liu, Z1
Brechbiel, MW1
Hanai, N1
Nice, EC1
Catimel, B1
Burgess, AW1
Welt, S1
Ritter, G1
Old, LJ1
Scott, AM1
Colao, A1
Dorato, M1
Pulcrano, M1
Rossi, FW1
Auriemma, RS1
Lombardi, G1
Lastoria, S1
Jánoki, GA1
Kerekes, A1
Martos, J1
Petersen, D1
Klose, U1
Requardt, H1
Buchholz, R1
Ohneseit, P1
Schabet, M1
Voigt, K1
Maughan, TS1
Page-Thomas, DP2
Premkumar, A1
Sanders, L1
Marincola, F1
Feuerstein, I1
Concepcion, R1
Schwartzentruber, D1
Adam, G3
Brab, M3
Bohndorf, K2
Klose, KC1
Günther, RW3
Reim, M1
Bond, JB1
Haik, BG1
Mihara, F1
Gupta, KL1
Schörner, W1
Schubeus, P1
Le Doussal, JM1
Gruaz-Guyon, A1
Martin, M1
Gautherot, E1
Delaage, M1
Barbet, J1
Hanna, SL1
Lemmi, MA1
Langston, JW1
Fontanesi, J1
Brooks, HL1
Gronemeyer, S1
Sardi, A1
Minton, JP1
Mojzisik, C1
Nieroda, CA1
Ferrara, PJ1
Hinkle, GH1
Thurston, MO1
Martin, EW1
Paik, CH1
Yokoyama, K1
Reynolds, JC1
Quadri, SM1
Min, CY1
Shin, SY1
Maloney, PJ1
Larson, SM1
Reba, RC1
NG, AK1
Alsedairy, S1
Hardy, MA2
Koizumi, M1
Endo, K1
Watanabe, Y1
Saga, T1
Sakahara, H1
Konishi, J1
Arano, Y1
Miyachi, Y1
Kashihara-Sawami, M1
Imamura, S1
Lin, DS1
Graif, M1
Steiner, RE1
Engelstad, BL1
Spitler, LE1
Del Rio, MJ1
Ramos, EC1
Rosendorf, LL1
Reinhold, CE1
Khentigan, A1
Huberty, JP1
Corpuz, SW1
Lee, HM1
Estabrook, A1
Rosen, JM1

Reviews

1 review available for pentetic acid and Malignant Melanoma

ArticleYear
[Somatostatin analogs in the clinical management of pituitary neoplasms].
    Minerva endocrinologica, 2001, Volume: 26, Issue:3

    Topics: Acromegaly; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Antineoplastic Agents, Hormon

2001

Trials

4 trials available for pentetic acid and Malignant Melanoma

ArticleYear
A phase 2 study of (99m)Tc-tilmanocept in the detection of sentinel lymph nodes in melanoma and breast cancer.
    Annals of surgical oncology, 2011, Volume: 18, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Dextrans; Female; Humans; Lymph Nodes; Lymphatic M

2011
Interim analysis of toxicity and response in phase 1 trial of systemic targeted alpha therapy for metastatic melanoma.
    Cancer biology & therapy, 2007, Volume: 6, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Agents; Biomarkers, Tumor; Co

2007
A double blind study to evaluate the tolerability of gadodiamide injection and its effect on renal function in patients undergoing cerebral magnetic resonance imaging.
    The British journal of radiology, 1993, Volume: 66, Issue:790

    Topics: Adult; Aged; Brain Neoplasms; Contrast Media; Double-Blind Method; Female; Gadolinium DTPA; Humans;

1993
The use of a chelating derivative of alpha melanocyte stimulating hormone for the clinical imaging of malignant melanoma.
    The British journal of radiology, 1992, Volume: 65, Issue:770

    Topics: Adult; Aged; Chelating Agents; Drug Evaluation; Female; Humans; Indium Radioisotopes; Lung Neoplasms

1992

Other Studies

39 other studies available for pentetic acid and Malignant Melanoma

ArticleYear
A Radiolabeled Self-assembled Nanoparticle Probe for Diagnosis of Lung-Metastatic Melanoma.
    Biological & pharmaceutical bulletin, 2021, Volume: 44, Issue:3

    Topics: Animals; Cell Line, Tumor; Dendrimers; Indium Radioisotopes; Iodine Radioisotopes; Lung Neoplasms; M

2021
Preparation of (99m)Tc carbonyl DTPA-bevacizumab and its bioevaluation in a melanoma model.
    Annals of nuclear medicine, 2014, Volume: 28, Issue:9

    Topics: Animals; Antibodies, Monoclonal, Humanized; Bevacizumab; Cell Line, Tumor; Chromatography, High Pres

2014
Pretargeted gamma imaging of murine metastatic melanoma lung lesions with bispecific antibody and radiolabeled polymer drug conjugates.
    Nuclear medicine communications, 2011, Volume: 32, Issue:12

    Topics: Animals; Antibodies, Bispecific; Antigens, Neoplasm; Feasibility Studies; Lung Neoplasms; Male; Mela

2011
Convenient solid-phase synthesis of diethylenetriaminepenta-acetic acid (DTPA)- conjugated cyclic RGD peptide analogues.
    Cancer biotherapy & radiopharmaceuticals, 2005, Volume: 20, Issue:5

    Topics: Amino Acid Motifs; Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Fluoresceins; Humans

2005
Dual optical and nuclear imaging in human melanoma xenografts using a single targeted imaging probe.
    Nuclear medicine and biology, 2006, Volume: 33, Issue:3

    Topics: Animals; Cell Adhesion; Cell Line, Tumor; Fluorescent Dyes; Humans; Indium Radioisotopes; Indoles; I

2006
A comparison of the cyclic anhydride and mixed anhydride methods for 111In-DTPA chelation to monoclonal antibodies.
    Nuklearmedizin. Nuclear medicine, 1984, Volume: 23, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Humans; Indium; Isotope Labeling; Melanoma; M

1984
Cerebral metastatic malignant melanoma: CT and MR findings with pathological correlation.
    Journal belge de radiologie, 1993, Volume: 76, Issue:5

    Topics: Aged; Aged, 80 and over; Brain Diseases; Brain Neoplasms; Contrast Media; Diagnosis, Differential; D

1993
BisMSH-DTPA. A potential imaging agent for malignant melanoma.
    Annals of the New York Academy of Sciences, 1993, May-31, Volume: 680

    Topics: Adult; Aged; False Negative Reactions; False Positive Reactions; Female; Humans; Indium Radioisotope

1993
Role of high-resolution magnetic resonance imaging for differentiating melanin-containing skin tumors.
    Investigative radiology, 1995, Volume: 30, Issue:11

    Topics: Adipose Tissue; Adolescent; Adult; Aged; Body Water; Contrast Media; Diagnosis, Differential; Drug C

1995
Fatty tissue on opposed-phase MR images: paradoxical suppression of signal intensity by paramagnetic contrast agents.
    Radiology, 1996, Volume: 198, Issue:2

    Topics: Adipose Tissue; Angiomyolipoma; Contrast Media; Drug Combinations; Fatty Liver; Gadolinium DTPA; Hem

1996
Failure of gadopentetate dimeglumine-enhanced, high-resolution magnetic resonance imaging to differentiate among melanin-containing skin tumors.
    Academic radiology, 1996, Volume: 3, Issue:3

    Topics: Adolescent; Adult; Diagnosis, Differential; Drug Combinations; Female; Gadolinium DTPA; Humans; Magn

1996
1H MR spectroscopy detection of lipids and lactate in metastatic brain tumors.
    NMR in biomedicine, 1996, Volume: 9, Issue:2

    Topics: Brain Neoplasms; Breast Neoplasms; Gadolinium DTPA; Humans; Lactates; Lipids; Lung Neoplasms; Magnet

1996
Primary malignant melanoma of the sinonasal cavity: MR imaging evaluation.
    Radiographics : a review publication of the Radiological Society of North America, Inc, 1996, Volume: 16, Issue:5

    Topics: Aged; Contrast Media; Drug Combinations; Female; Gadolinium DTPA; Humans; Magnetic Resonance Imaging

1996
Clinical relevance of 111In-octreotide scans in CNS tumors.
    The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), 1995, Volume: 39, Issue:4 Suppl 1

    Topics: Brain Neoplasms; Central Nervous System Neoplasms; Diagnosis, Differential; Follow-Up Studies; Froze

1995
MRI diagnosis of intramedullary metastases from extra-CNS tumors.
    European radiology, 1997, Volume: 7, Issue:5

    Topics: Breast Neoplasms; Contrast Media; Female; Gadolinium; Gadolinium DTPA; Humans; Lung Neoplasms; Magne

1997
A special surface coil for high-resolution ocular MRI.
    Frontiers of radiation therapy and oncology, 1997, Volume: 30

    Topics: Child; Contrast Media; Echo-Planar Imaging; Eye; Eye Neoplasms; Gadolinium; Gadolinium DTPA; Humans;

1997
[A rare differential diagnosis of suspicious contrast medium enhancement in breast MRI. Melanoma metastasis in both breasts].
    Der Radiologe, 1997, Volume: 37, Issue:7

    Topics: Breast; Breast Neoplasms; Contrast Media; Female; Gadolinium DTPA; Humans; Magnetic Resonance Imagin

1997
Radioimmunoconjugates for targeted alpha therapy of malignant melanoma.
    Melanoma research, 2000, Volume: 10, Issue:3

    Topics: Antibodies, Monoclonal; Bismuth; Chelating Agents; DNA, Neoplasm; Humans; Immunoconjugates; Isothioc

2000
Rapid imaging of human melanoma xenografts using an scFv fragment of the human monoclonal antibody H11 labelled with 111In.
    Nuclear medicine communications, 2001, Volume: 22, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Female; Humans; Immunoglobulin Variable Region; Indium Radioisotope

2001
Specific localization, gamma camera imaging, and intracellular trafficking of radiolabelled chimeric anti-G(D3) ganglioside monoclonal antibody KM871 in SK-MEL-28 melanoma xenografts.
    Cancer research, 2001, Jun-01, Volume: 61, Issue:11

    Topics: Animals; Antibodies, Monoclonal; Chelating Agents; Female; Gamma Cameras; Gangliosides; Humans; Immu

2001
Pharmacokinetics of radiopharmaceuticals.
    Acta physiologica Hungarica, 1992, Volume: 79, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Bile; Carcinoembryonic Antigen; Chromatography, High Pressure Liqui

1992
MR imaging of experimental meningeal melanomatosis in nude rats.
    Journal of neuro-oncology, 1992, Volume: 14, Issue:3

    Topics: Animals; Cisterna Magna; Contrast Media; Female; Gadolinium DTPA; Magnetic Resonance Imaging; Melano

1992
Visceral metastases from melanoma: findings on MR imaging.
    AJR. American journal of roentgenology, 1992, Volume: 158, Issue:2

    Topics: Abdominal Neoplasms; Adult; Central Nervous System Neoplasms; Contrast Media; Drug Combinations; Eye

1992
[Contrast-enhanced MRT of malignant melanoma of the uvea].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1991, Volume: 154, Issue:3

    Topics: Adult; Aged; Contrast Media; Female; Gadolinium; Gadolinium DTPA; Humans; Iris Neoplasms; Magnetic R

1991
[Differential intraocular tumor diagnosis in MRI using gadolinium DTPA: value in comparison with other ophthalmologic examination procedures].
    Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1991, Volume: 88, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Eye; Eye Neoplasms; Female; Gadolinium DTPA; Humans;

1991
Magnetic resonance imaging of choroidal melanoma with and without gadolinium contrast enhancement.
    Ophthalmology, 1991, Volume: 98, Issue:4

    Topics: Choroid Neoplasms; Gadolinium; Gadolinium DTPA; Humans; Image Enhancement; Magnetic Resonance Imagin

1991
[MRT of brain metastases. (I) What is the place of screening with T2-weighted sequences?].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1990, Volume: 153, Issue:3

    Topics: Adult; Aged; Brain Neoplasms; Breast Neoplasms; Carcinoma, Bronchogenic; Gadolinium; Gadolinium DTPA

1990
A chelating derivative of alpha-melanocyte stimulating hormone as a potential imaging agent for malignant melanoma.
    British journal of cancer, 1990, Volume: 62, Issue:6

    Topics: Animals; Drug Stability; Indium Radioisotopes; Melanocyte-Stimulating Hormones; Melanoma; Mice; Mice

1990
Gadolinium-DTPA-enhanced MRI of intraocular tumors.
    Magnetic resonance imaging, 1990, Volume: 8, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Ciliary Body; Contrast Media; Eye Neoplasms; Female; Gadolinium DTPA

1990
Targeting of indium 111-labeled bivalent hapten to human melanoma mediated by bispecific monoclonal antibody conjugates: imaging of tumors hosted in nude mice.
    Cancer research, 1990, Jun-01, Volume: 50, Issue:11

    Topics: Animals; Antibodies; Antibody Specificity; Antigens, Neoplasm; Female; Haptens; Humans; Immunoglobul

1990
Treatment of choroidal melanoma: MR imaging in the assessment of radioactive plaque position.
    Radiology, 1990, Volume: 176, Issue:3

    Topics: Aged; Brachytherapy; Choroid Neoplasms; Contrast Media; Gadolinium DTPA; Humans; Iodine Radioisotope

1990
The use of a hand-held gamma detector improves the safety of isolated limb perfusion.
    Journal of surgical oncology, 1989, Volume: 41, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Extr

1989
Reduction of background activities by introduction of a diester linkage between antibody and a chelate in radioimmunodetection of tumor.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1989, Volume: 30, Issue:10

    Topics: Animals; Antibodies, Monoclonal; Binding, Competitive; Chemical Phenomena; Chemistry; Humans; Indium

1989
A method for direct quantification of the amount of DTPA in 111In monoclonal antibody preparations.
    International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 1987, Volume: 38, Issue:4

    Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Cell Line; HLA-D Antigens; HLA-DR Antigens; Humans; Indi

1987
Immunoscintigraphy and pharmacokinetics of indium-111-labeled ZME-018 monoclonal antibody in patients with malignant melanoma.
    Japanese journal of cancer research : Gann, 1988, Volume: 79, Issue:8

    Topics: Adult; Aged; Animals; Antibodies, Monoclonal; Humans; Indium Radioisotopes; Infusions, Intravenous;

1988
Hypervascularity on cerebral radionuclide angiogram.
    Seminars in nuclear medicine, 1986, Volume: 16, Issue:1

    Topics: Brain Neoplasms; Humans; Male; Melanoma; Middle Aged; Pentetic Acid; Radionuclide Imaging; Technetiu

1986
Contrast-enhanced magnetic resonance imaging of tumours of the central nervous system: a clinical review.
    The British journal of radiology, 1986, Volume: 59, Issue:705

    Topics: Astrocytoma; Brain Neoplasms; Breast Neoplasms; Female; Gadolinium; Humans; Magnetic Resonance Spect

1986
Phase 1 immunolymphoscintigraphy with an In-111-labeled antimelanoma monoclonal antibody.
    Radiology, 1986, Volume: 161, Issue:2

    Topics: Adult; Antibodies, Monoclonal; Female; Humans; Indium; Lymphatic Metastasis; Male; Melanoma; Middle

1986
Immunoreactivity and biodistribution of indium-111-labeled monoclonal antibody to a human high molecular weight-melanoma associated antigen.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1985, Volume: 26, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Cell Line; Cells, Cultured; Humans; Indium; Iso

1985