Page last updated: 2024-10-26

pentetic acid and Insulinoma

pentetic acid has been researched along with Insulinoma in 16 studies

Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.

Insulinoma: A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA.

Research Excerpts

ExcerptRelevanceReference
"Small benign insulinomas are hard to localise, leading to difficulties in planning of surgical interventions."2.78Glucagon-like peptide-1 receptor imaging for the localisation of insulinomas: a prospective multicentre imaging study. ( Béhé, M; Brändle, M; Caplin, ME; Christ, E; Clerici, T; Ederer, S; Ell, PJ; Fischli, S; Forrer, F; Gloor, B; Nicolas, G; Perren, A; Reubi, JC; Seufert, J; Stettler, C; Wild, D, 2013)
"Insulinomas are neuroendocrine tumours derived from pancreatic beta-cells."1.3668Ga-labelled exendin-3, a new agent for the detection of insulinomas with PET. ( Boerman, OC; Brom, M; Gotthardt, M; Joosten, L; Oyen, WJ, 2010)
"Insulinomas are rare endocrine tumors that are mostly sporadic, benign, and small."1.33Intraoperative gamma probe detection of lymph node recurrence of insulinoma. ( Busquets, J; Grande, L; Miralles, EM; Miret, M; Munné, A; Ortega, M; Pelaez, N; Puig, J, 2005)
"Of the 60 evaluable patients, 51 had carcinoid tumours, 3 gastrinomas, 2 glucagonomas, 1 insulinoma and 3 paragangliomas."1.33Added value of gastrin receptor scintigraphy in comparison to somatostatin receptor scintigraphy in patients with carcinoids and other neuroendocrine tumours. ( Arnold, R; Bauhofer, A; Béhé, MP; Behr, TM; Gotthardt, M; Grass, J; Kalinowski, M; Oyen, WJ; Rinke, A; Schipper, ML, 2006)
"Insulinoma is a rare endocrine tumour in the elderly."1.31Intraoperative gamma probe detection of insulinoma in an elderly patient with pancreatic cystic lesions. ( Donckier, JE; Ernst, YJ; Michel, L; Roelants, V; Rosière, A; Vander Borght, T, 2002)
"Patient 1 had a metastatic follicular thyroid carcinoma, patient 2 a metastatic medullary thyroid carcinoma, patient 3 tuberculosis and patient 4 an insulinoma."1.30Somatostatin receptor scintigraphy using [111In-DTPA0]RC-160 in humans: a comparison with [111In-DTPA0]octreotide. ( Breeman, WA; Krenning, EP; Kwekkeboom, DJ; van Hagen, PM; Visser, TJ, 1998)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (50.00)18.2507
2000's4 (25.00)29.6817
2010's4 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cuccurullo, V1
Di Stasio, GD1
Mansi, L1
Grossman, A1
Christ, E1
Wild, D2
Ederer, S1
Béhé, M2
Nicolas, G1
Caplin, ME1
Brändle, M1
Clerici, T1
Fischli, S1
Stettler, C1
Ell, PJ1
Seufert, J1
Gloor, B1
Perren, A1
Reubi, JC2
Forrer, F1
Brom, M1
Oyen, WJ2
Joosten, L1
Gotthardt, M3
Boerman, OC1
Rosière, A1
Ernst, YJ1
Roelants, V1
Vander Borght, T1
Michel, L1
Donckier, JE1
Pelaez, N1
Busquets, J1
Ortega, M1
Miralles, EM1
Puig, J1
Miret, M1
Munné, A1
Grande, L1
Béhé, MP1
Grass, J1
Bauhofer, A1
Rinke, A1
Schipper, ML1
Kalinowski, M1
Arnold, R2
Behr, TM1
Wicki, A1
Storch, D1
Seemayer, C1
Kneifel, S1
Mihatsch, MJ1
Mäcke, HR1
Christofori, G1
Modlin, IM1
Cornelius, E1
Lawton, GP1
Weinel, RJ1
Kisker, O1
Joseph, K2
Welcke, U1
Zaraca, F1
Rothmund, M1
Ur, E1
Bomanji, J1
Mather, SJ1
Britton, KE1
Wass, JA1
Grossman, AB1
Besser, GM1
Krausz, Y1
Shibley, N1
De Jong, RB1
Yaffe, S1
Glaser, B1
Stapp, J1
Reinecke, J1
Skamel, HJ1
Höffken, H1
Neuhaus, C1
Lenze, H1
Trautmann, ME1
Yamamoto, K1
Ishii, Y1
Furudate, M1
Ito, K1
Tsukamoto, E1
Kanamaru, R1
Endo, K1
Hirano, T1
Tanaka, K1
Ogino, Y1
Robben, JH1
Visser-Wisselaar, HA1
Rutteman, GR1
van Rijk, PP1
van Dongen, AJ1
Voorhout, G1
van den Ingh, TS1
Hofland, LJ1
Lamberts, SW1
Breeman, WA1
van Hagen, PM1
Kwekkeboom, DJ1
Visser, TJ1
Krenning, EP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
New Imaging Procedure for the Localisation of Insulinoma[NCT02127541]52 participants (Actual)Interventional2014-01-06Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for pentetic acid and Insulinoma

ArticleYear
Physiopathological Premises to Nuclear Medicine Imaging of Pancreatic Neuroendocrine Tumours.
    Current radiopharmaceuticals, 2019, Volume: 12, Issue:2

    Topics: Animals; Dihydroxyphenylalanine; Dimerization; Edetic Acid; Fluorodeoxyglucose F18; Glucagon-Like Pe

2019
Use of an isotopic somatostatin receptor probe to image gut endocrine tumors.
    Archives of surgery (Chicago, Ill. : 1960), 1995, Volume: 130, Issue:4

    Topics: Adult; Aged; Carcinoid Tumor; Duodenal Neoplasms; Female; Gastrinoma; Humans; Indium Radioisotopes;

1995

Trials

3 trials available for pentetic acid and Insulinoma

ArticleYear
Glucagon-like peptide-1 receptor imaging for the localisation of insulinomas: a prospective multicentre imaging study.
    The lancet. Diabetes & endocrinology, 2013, Volume: 1, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Exenatide; Female; Glucagon-Like Peptide-1 Receptor; Humans; Indium

2013
Use of an isotopic somatostatin receptor probe to image gut endocrine tumors.
    Archives of surgery (Chicago, Ill. : 1960), 1995, Volume: 130, Issue:4

    Topics: Adult; Aged; Carcinoid Tumor; Duodenal Neoplasms; Female; Gastrinoma; Humans; Indium Radioisotopes;

1995
[Phase 3 multicenter clinical study of 111In-DTPA-D-octreotide (MP-1727) in patients with gastrointestinal hormone producing tumors].
    Kaku igaku. The Japanese journal of nuclear medicine, 1995, Volume: 32, Issue:11

    Topics: Adult; Aged; Carcinoid Tumor; Female; Gastrinoma; Glucagonoma; Humans; Indium Radioisotopes; Insulin

1995

Other Studies

12 other studies available for pentetic acid and Insulinoma

ArticleYear
The nuclear option for insulinomas.
    The lancet. Diabetes & endocrinology, 2013, Volume: 1, Issue:2

    Topics: Exenatide; Female; Humans; Indium Radioisotopes; Insulinoma; Male; Pancreatic Neoplasms; Pentetic Ac

2013
68Ga-labelled exendin-3, a new agent for the detection of insulinomas with PET.
    European journal of nuclear medicine and molecular imaging, 2010, Volume: 37, Issue:7

    Topics: Amino Acid Sequence; Animals; Biological Transport; Cell Line, Tumor; Dose-Response Relationship, Dr

2010
Intraoperative gamma probe detection of insulinoma in an elderly patient with pancreatic cystic lesions.
    Clinical endocrinology, 2002, Volume: 57, Issue:4

    Topics: Aged; Aged, 80 and over; Female; Humans; Indium Radioisotopes; Insulinoma; Intraoperative Period; Oc

2002
Intraoperative gamma probe detection of lymph node recurrence of insulinoma.
    Journal of surgical oncology, 2005, Sep-01, Volume: 91, Issue:3

    Topics: Aged; Female; Humans; Insulinoma; Intraoperative Care; Lymph Node Excision; Lymphatic Metastasis; Oc

2005
Added value of gastrin receptor scintigraphy in comparison to somatostatin receptor scintigraphy in patients with carcinoids and other neuroendocrine tumours.
    Endocrine-related cancer, 2006, Volume: 13, Issue:4

    Topics: Adult; Aged; Carcinoid Tumor; Diagnosis, Differential; Female; Glucagonoma; Humans; Indium Radioisot

2006
[Lys40(Ahx-DTPA-111In)NH2]-Exendin-4 is a highly efficient radiotherapeutic for glucagon-like peptide-1 receptor-targeted therapy for insulinoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Jun-15, Volume: 13, Issue:12

    Topics: Animals; Cell Proliferation; Female; Glucagon-Like Peptide-1 Receptor; Indium Radioisotopes; Insulin

2007
[Somatostatin receptor scintigraphy in preoperative diagnosis of the site of endocrine gastrointestinal tumors].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1994, Volume: 65, Issue:10

    Topics: Biomarkers, Tumor; Carcinoid Tumor; Gastrinoma; Gastrointestinal Neoplasms; Humans; Indium Radioisot

1994
Localization of neuroendocrine tumours and insulinomas using radiolabelled somatostatin analogues, 123I-Tyr3-octreotide and 111In-pentatreotide.
    Clinical endocrinology, 1993, Volume: 38, Issue:5

    Topics: Adult; Aged; Evaluation Studies as Topic; Female; Humans; Indium Radioisotopes; Insulinoma; Iodine R

1993
Gallbladder visualization with In-111 labeled octreotide.
    Clinical nuclear medicine, 1994, Volume: 19, Issue:2

    Topics: False Negative Reactions; False Positive Reactions; Fasting; Female; Gallbladder; Humans; Indium Rad

1994
Receptor scintigraphy with 111In-pentetreotide for endocrine gastroenteropancreatic tumors.
    Hormone and metabolic research. Supplement series, 1993, Volume: 27

    Topics: Aged; Carcinoid Tumor; Gastrinoma; Gastrointestinal Neoplasms; Humans; Indium Radioisotopes; Insulin

1993
In vitro and in vivo detection of functional somatostatin receptors in canine insulinomas.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:7

    Topics: Animals; Autoradiography; Blood Glucose; Dogs; Female; Indium Radioisotopes; Insulin; Insulinoma; Io

1997
Somatostatin receptor scintigraphy using [111In-DTPA0]RC-160 in humans: a comparison with [111In-DTPA0]octreotide.
    European journal of nuclear medicine, 1998, Volume: 25, Issue:2

    Topics: Adenocarcinoma, Follicular; Adult; Carcinoma, Medullary; Female; Humans; Indium Radioisotopes; Insul

1998