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pentetic acid and Graves Disease

pentetic acid has been researched along with Graves Disease in 9 studies

Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.

Graves Disease: A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).

Research Excerpts

ExcerptRelevanceReference
"Visualization of thyroidal and orbital Graves' disease is feasible, but further investigation is necessary to establish the role of [111In-DTPA-D-Phe1]octreotide scintigraphy in representing disease activity and expression and in predicting therapeutical outcome."1.29[111In-DTPA-D-Phe1] octreotide scintigraphy in thyroidal and orbital Graves' disease: a parameter for disease activity? ( Hooijkaas, H; Kooy, PP; Krenning, EP; Oei, HY; Postema, PT; Reubi, JC; van den Bosch, WA; van der Loos, T; Wiersinga, WM; Wijngaarde, R, 1994)
"Seven patients with exophthalmos were investigated: six had GD while one was affected with a non small cell lung cancer (NSCLC)."1.29Indium-111 octreotide in Graves' disease and in the evaluation of active exophthalmos. ( Bizzarro, A; De Bellis, A; Del Vecchio, E; Di Martino, S; Mansi, L; Panza, N; Rambaldi, PF, 1995)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's5 (55.56)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Savastano, S1
Pivonello, R3
Acampa, W1
Salvatore, M1
Lombardi, G3
Colao, A3
Fenzi, G3
Alevizaki-Harhalaki, M1
Alevizaki, C1
Georgiou, E1
Proukauis, C1
Ikkos, D1
Postema, PT2
Krenning, EP3
Wijngaarde, R1
Kooy, PP1
Oei, HY1
van den Bosch, WA1
Reubi, JC1
Wiersinga, WM2
Hooijkaas, H1
van der Loos, T1
Mansi, L1
Rambaldi, PF1
Bizzarro, A1
Panza, N1
Di Martino, S1
De Bellis, A1
Del Vecchio, E1
Kwekkeboom, DJ1
van Hagen, PM1
Lastoria, S2
Ferone, D2
Macchia, PE1
Vassallo, P1
Bonavolonta, G1
Muto, P1
Gerding, MN1
van der Zant, FM1
van Royen, EA1
Koornneef, L1
Prummel, MF1
Faggiano, A1
Markl, A1
Riedel, KG1
Oeckler, R1
Vogl, T1
Scheidhauer, K1

Reviews

1 review available for pentetic acid and Graves Disease

ArticleYear
Clinical implications of somatostatin-receptor scintigraphy in ophthalmic Graves' disease.
    European journal of endocrinology, 2000, Volume: 143 Suppl 1

    Topics: Graves Disease; Humans; Indium Radioisotopes; Octreotide; Pentetic Acid; Radionuclide Imaging; Radio

2000

Trials

1 trial available for pentetic acid and Graves Disease

ArticleYear
Orbital scintigraphy with [111In-diethylenetriamine pentaacetic acid-D-phe1]-octreotide predicts the clinical response to corticosteroid therapy in patients with Graves' ophthalmopathy.
    The Journal of clinical endocrinology and metabolism, 1998, Volume: 83, Issue:11

    Topics: Adult; Female; Glucocorticoids; Graves Disease; Humans; Indium Radioisotopes; Male; Methylprednisolo

1998

Other Studies

7 other studies available for pentetic acid and Graves Disease

ArticleYear
Recombinant thyrotropin-induced orbital uptake of [111In-diethylenetriamine-pentacetic acid-D-Phe1]octreotide in a patient with inactive Graves' ophthalmopathy.
    The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:4

    Topics: Female; Graves Disease; Humans; Indium Radioisotopes; Middle Aged; Octreotide; Orbit; Pentetic Acid;

2005
Increased Tc-99m DTPA uptake in active Graves' ophthalmopathy and pretibial myxoedema.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1983, Volume: 24, Issue:2

    Topics: Female; Graves Disease; Humans; Leg Dermatoses; Male; Middle Aged; Myxedema; Pentetic Acid; Radionuc

1983
[111In-DTPA-D-Phe1] octreotide scintigraphy in thyroidal and orbital Graves' disease: a parameter for disease activity?
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 79, Issue:6

    Topics: Eye; Eye Diseases; Graves Disease; Humans; Indium Radioisotopes; Methimazole; Octreotide; Pentetic A

1994
Indium-111 octreotide in Graves' disease and in the evaluation of active exophthalmos.
    The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), 1995, Volume: 39, Issue:2

    Topics: Adult; Exophthalmos; Female; Graves Disease; Humans; Indium Radioisotopes; Male; Middle Aged; Octreo

1995
Somatostatin-receptor scintigraphy in Graves' orbitopathy.
    European journal of nuclear medicine, 1996, Volume: 23, Issue:6

    Topics: Graves Disease; Humans; Indium Radioisotopes; Octreotide; Pentetic Acid; Radionuclide Imaging; Recep

1996
Octreotide-scintigraphy is a disease-activity parameter in Graves' ophthalmopathy.
    Clinical endocrinology, 1999, Volume: 50, Issue:3

    Topics: Adult; Evaluation Studies as Topic; Female; Graves Disease; Hormones; Humans; Indium Radioisotopes;

1999
[Nuclear magnetic resonance tomography of the orbits. Initial experiences using the paramagnetic contrast medium gadolinium-DTPA].
    Digitale Bilddiagnostik, 1986, Volume: 6, Issue:4

    Topics: Adult; Aged; Contrast Media; Female; Gadolinium; Graves Disease; Humans; Magnetic Resonance Spectros

1986