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pentetic acid and Experimental Mammary Neoplasms

pentetic acid has been researched along with Experimental Mammary Neoplasms in 36 studies

Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.

Research Excerpts

ExcerptRelevanceReference
" Radioimmunotherapy was also combined with a single injection of 300 microg paclitaxel to explore improved efficacy."1.34Radioimmunotherapy with alpha-particle emitting 213Bi-C-functionalized trans-cyclohexyl-diethylenetriaminepentaacetic acid-humanized 3S193 is enhanced by combination with paclitaxel chemotherapy. ( Brechbiel, MW; Kelly, MP; Lee, FT; Scott, AM; Smyth, FE; Tahtis, K, 2007)
"DTPA-paclitaxel was labeled with 111In with a radiochemical yield of 84% and radiochemical purity of 90%."1.30Synthesis, biodistribution and imaging properties of indium-111-DTPA-paclitaxel in mice bearing mammary tumors. ( Hunter, NR; Inoue, T; Kim, EE; Li, C; Liu, CW; Milas, L; Tansey, W; Wallace, S; Yang, DJ; Yu, DF, 1997)
"The in vivo response of MCF-7 breast cancer xenografts to tamoxifen and DTPA-Tam in nude mice demonstrated that DTPA-Tam could reduce tumor growth rate."1.29Synthesis, biodistribution, and estrogen receptor scintigraphy of indium-111-diethylenetriaminepentaacetic acid-tamoxifen analogue. ( Cherif, A; Delpassand, ES; Inoue, T; Joubert, A; Podoloff, DA; Price, J; Quadri, SM; Wallace, S; Yang, DJ, 1996)
" By simultaneously monitoring the effects in various tissues, the pharmacokinetic effect of each drug in the entire body could be obtained."1.29Pharmacokinetic changes induced by vasomodulators in kidneys, livers, muscles, and implanted tumors in rats as measured by dynamic Gd-DTPA-enhanced MRI. ( Lao, X; Nalcioglu, O; Roth, GM; Samoszuk, MK; Su, MY; Wang, Z, 1996)
"Five normal rats, 14 rats bearing the Rous sarcoma intrarenally, and four rats with DMBA-induced mammary carcinomas were imaged by dynamic (18F)-2-fluoro-2-deoxy-D-glucose ((18F)FDG) scintigraphy and (99mTc)DTPA renography."1.27Dynamic (18F)-2-fluoro-2-deoxy-D-glucose (FDG) scintigraphy of normal and tumor-bearing rats. ( Parviainen, S; Paul, R, 1986)
"An animal model of liver cancer was used to demonstrate that with a fast MRI technique, Gadolinium-DTPA increases tumor-liver contrast."1.27Dynamic spin-echo MRI of liver cancer using Gadolinium-DTPA: animal investigation. ( Brady, TJ; Ferrucci, JT; Saini, S; Stark, DD; Wittenberg, J, 1986)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19904 (11.11)18.7374
1990's25 (69.44)18.2507
2000's2 (5.56)29.6817
2010's5 (13.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khaw, BA1
Gada, KS1
Patil, V1
Panwar, R1
Mandapati, S1
Hatefi, A1
Majewski, S1
Weisenberger, A1
Hajmohammadi, M2
Siadat, SD1
Ghorbani, M1
Shafiee Ardestani, M1
Teimourian, S1
Asgari, V1
Ahangari Cohan, R1
Hajmohammadi, A1
Behzadi, R1
Rajab Nezhad, S1
Namvar Asl, N1
Saha, A1
Ellison, D1
Thomas, GJ1
Vallath, S1
Mather, SJ1
Hart, IR1
Marshall, JF1
Lingappa, M1
Song, H1
Thompson, S1
Bruchertseifer, F1
Morgenstern, A1
Sgouros, G1
Ye, Z1
Jeong, EK1
Wu, X1
Tan, M1
Yin, S1
Lu, ZR1
Smith-Jones, PM1
Solit, DB1
Kelly, MP1
Lee, FT1
Tahtis, K1
Smyth, FE1
Brechbiel, MW1
Scott, AM1
Donahue, KM2
Weisskoff, RM2
Parmelee, DJ1
Callahan, RJ1
Wilkinson, RA1
Mandeville, JB2
Rosen, BR2
Schwickert, HC5
Roberts, TP6
Mühler, A5
Stiskal, M3
Demsar, F6
Brasch, RC9
Cohen, FM2
Kuwatsuru, R3
Shames, DM8
Neuder, M2
Mann, JS6
Vexler, V3
Rosenau, W2
Kennedy, SD1
Szczepaniak, LS1
Gibson, SL1
Hilf, R1
Foster, TH1
Bryant, RG1
Bacić, G2
Liu, KJ1
O'Hara, JA2
Harris, RD1
Szybinski, K1
Goda, F2
Swartz, HM2
Harika, L1
Weissleder, R2
Poss, K1
Papisov, MI1
van Dijke, CF5
Weidner, N1
Mathur, A1
Lang, P1
Mann, J1
Disston, A1
Gallez, B1
Dunn, JF1
Delpassand, ES1
Yang, DJ5
Wallace, S3
Cherif, A1
Quadri, SM1
Price, J1
Joubert, A1
Inoue, T4
Podoloff, DA4
Saeed, M1
Schmidt, HC1
Kovar, DA2
Lipton, MJ2
Lewis, MZ2
River, JN2
Lubich, L1
Karczmar, GS2
Chesler, DA1
Kwong, KK1
Bogdanov, AA1
Su, MY1
Wang, Z1
Roth, GM1
Lao, X1
Samoszuk, MK1
Nalcioglu, O1
Li, C2
Yu, DF1
Tansey, W1
Liu, CW1
Milas, L2
Hunter, NR1
Kim, EE4
Higuchi, T3
Ilgan, S2
Tansey, LW1
Zareneyrizi, F2
Endo, K1
Oriuchi, N1
Yu, D1
Hunter, N1
Volf, V1
Luz, A1
Schäffer, E1
Müller, WA1
Rencová, J1
Schomäcker, K1
Franke, WG1
Jantsch, K1
Shukla, SK1
Limouris, GS1
Kennedy, KA1
Mimnaugh, EG1
Trush, MA1
Sinha, BK1
Paul, R1
Parviainen, S1
Saini, S2
Stark, DD2
Wittenberg, J2
Ferrucci, JT2
Brady, TJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Tumor Oximetry Using Electron Paramagnetic Resonance (EPR) With India Ink (Using Carbon Particulates From Carlo Erba [CE])[NCT03321903]3 participants (Actual)Observational2017-08-30Terminated (stopped due to The research team is exploring device optimization)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

36 other studies available for pentetic acid and Experimental Mammary Neoplasms

ArticleYear
Bispecific antibody complex pre-targeting and targeted delivery of polymer drug conjugates for imaging and therapy in dual human mammary cancer xenografts: targeted polymer drug conjugates for cancer diagnosis and therapy.
    European journal of nuclear medicine and molecular imaging, 2014, Volume: 41, Issue:8

    Topics: Animals; Antibodies, Bispecific; Carcinoma; Cell Line, Tumor; Doxorubicin; Drug Carriers; Female; Hu

2014
Synthesis and characterization of a novel chemically designed (Globo)3-DTPA-KLH antigen.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Adjuvants, Immunologic; Animals; Antigens, Tumor-Associated, Carbohydrate; Cancer Vaccines; Drug Des

2015
High-resolution in vivo imaging of breast cancer by targeting the pro-invasive integrin alphavbeta6.
    The Journal of pathology, 2010, Volume: 222, Issue:1

    Topics: Animals; Antigens, Neoplasm; Female; Humans; Indium Radioisotopes; Integrins; Mammary Neoplasms, Exp

2010
Immunoliposomal delivery of 213Bi for alpha-emitter targeting of metastatic breast cancer.
    Cancer research, 2010, Sep-01, Volume: 70, Issue:17

    Topics: Alpha Particles; Animals; Bismuth; Female; Immunoconjugates; Isothiocyanates; Liposomes; Mammary Neo

2010
Polydisulfide manganese(II) complexes as non-gadolinium biodegradable macromolecular MRI contrast agents.
    Journal of magnetic resonance imaging : JMRI, 2012, Volume: 35, Issue:3

    Topics: Animals; Contrast Media; Disulfides; Edetic Acid; Female; Humans; Macromolecular Substances; Magneti

2012
Generation of DOTA-conjugated antibody fragments for radioimmunoimaging.
    Methods in enzymology, 2004, Volume: 386

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigen-Antibody Reactions; Cell

2004
Radioimmunotherapy with alpha-particle emitting 213Bi-C-functionalized trans-cyclohexyl-diethylenetriaminepentaacetic acid-humanized 3S193 is enhanced by combination with paclitaxel chemotherapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Sep-15, Volume: 13, Issue:18 Pt 2

    Topics: Alpha Particles; Animals; Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Apoptosis; Bism

2007
Dynamic Gd-DTPA enhanced MRI measurement of tissue cell volume fraction.
    Magnetic resonance in medicine, 1995, Volume: 34, Issue:3

    Topics: Animals; Cell Size; Computer Simulation; Contrast Media; Female; Gadolinium DTPA; Liver; Magnetic Re

1995
Angiographic properties of Gd-DTPA-24-cascade-polymer--a new macromolecular MR contrast agent.
    European journal of radiology, 1995, Volume: 20, Issue:2

    Topics: Adenocarcinoma; Animals; Contrast Media; Female; Gadolinium DTPA; Macromolecular Substances; Magneti

1995
Contrast-enhanced magnetic resonance imaging estimation of altered capillary permeability in experimental mammary carcinomas after X-irradiation.
    Investigative radiology, 1994, Volume: 29, Issue:11

    Topics: Adenocarcinoma; Albumins; Animals; Capillaries; Capillary Permeability; Contrast Media; Endothelium,

1994
Quantification of capillary permeability to macromolecular magnetic resonance imaging contrast media in experimental mammary adenocarcinomas.
    Investigative radiology, 1994, Volume: 29 Suppl 2

    Topics: Adenocarcinoma; Albumins; Animals; Capillary Permeability; Contrast Media; Female; Gadolinium DTPA;

1994
Quantitative MRI of Gd-DTPA uptake in tumors: response to photodynamic therapy.
    Magnetic resonance in medicine, 1994, Volume: 31, Issue:3

    Topics: Adenocarcinoma; Adenosine Triphosphate; Animals; Contrast Media; Female; Gadolinium DTPA; Magnetic R

1994
Oxygen tension in a murine tumor: a combined EPR and MRI study.
    Magnetic resonance in medicine, 1993, Volume: 30, Issue:5

    Topics: Animals; Carbon; Coal; Contrast Media; Electron Spin Resonance Spectroscopy; Female; Gadolinium DTPA

1993
Measurement of capillary permeability to macromolecules by dynamic magnetic resonance imaging: a quantitative noninvasive technique.
    Magnetic resonance in medicine, 1993, Volume: 29, Issue:5

    Topics: Algorithms; Animals; Capillary Permeability; Contrast Media; Female; Gadolinium DTPA; Macromolecular

1993
Macromolecular intravenous contrast agent for MR lymphography: characterization and efficacy studies.
    Radiology, 1996, Volume: 198, Issue:2

    Topics: Animals; Contrast Media; Female; Gadolinium DTPA; Guinea Pigs; Half-Life; Indium Radioisotopes; Inje

1996
Mammary carcinoma model: correlation of macromolecular contrast-enhanced MR imaging characterizations of tumor microvasculature and histologic capillary density.
    Radiology, 1996, Volume: 198, Issue:3

    Topics: Albumins; Animals; Capillaries; Contrast Media; Female; Gadolinium DTPA; Macromolecular Substances;

1996
Contrast-enhanced MR imaging assessment of tumor capillary permeability: effect of irradiation on delivery of chemotherapy.
    Radiology, 1996, Volume: 198, Issue:3

    Topics: Albumins; Animals; Antineoplastic Agents; Capillary Permeability; Cisplatin; Contrast Media; Dose-Re

1996
The relationship between partial pressure of oxygen and perfusion in two murine tumors after X-ray irradiation: a combined gadopentetate dimeglumine dynamic magnetic resonance imaging and in vivo electron paramagnetic resonance oximetry study.
    Cancer research, 1996, Jul-15, Volume: 56, Issue:14

    Topics: Animals; Electron Spin Resonance Spectroscopy; Female; Fibrosarcoma; Gadolinium DTPA; Magnetic Reson

1996
Synthesis, biodistribution, and estrogen receptor scintigraphy of indium-111-diethylenetriaminepentaacetic acid-tamoxifen analogue.
    Journal of pharmaceutical sciences, 1996, Volume: 85, Issue:6

    Topics: Animals; Autoradiography; Breast Neoplasms; Estradiol; Female; Humans; Indium Radioisotopes; Kinetic

1996
Spatial mapping of microvascular permeability and tissue blood volume using magnetic resonance imaging.
    Academic radiology, 1996, Volume: 3 Suppl 2

    Topics: Adenocarcinoma; Albumins; Animals; Capillary Permeability; Contrast Media; Coronary Circulation; Cor

1996
Time and dose dependency of radiation-induced changes in tumor microvascular characteristics using contrast-enhanced magnetic resonance imaging: impact on the delivery of chemotherapeutic agents.
    Academic radiology, 1996, Volume: 3 Suppl 2

    Topics: Adenocarcinoma; Albumins; Animals; Antineoplastic Agents; Capillary Permeability; Cisplatin; Contras

1996
Dynamic contrast measurements in rodent model tumors.
    Academic radiology, 1996, Volume: 3 Suppl 2

    Topics: Animals; Blood Flow Velocity; Carcinoma, Squamous Cell; Contrast Media; Female; Gadolinium DTPA; Mag

1996
Definition of peritumoral vessels with contrast-enhanced magnetic resonance imaging: comparison of gadopentetate dimeglumine and a blood-pool macromolecular contrast medium.
    Academic radiology, 1996, Volume: 3 Suppl 2

    Topics: Albumins; Animals; Contrast Media; Drug Combinations; Gadolinium DTPA; Magnetic Resonance Imaging; M

1996
Improving MR quantification of regional blood volume with intravascular T1 contrast agents: accuracy, precision, and water exchange.
    Magnetic resonance in medicine, 1996, Volume: 36, Issue:6

    Topics: Adenocarcinoma; Animals; Blood Vessels; Blood Volume; Cell Transplantation; Computer Simulation; Con

1996
Pharmacokinetic changes induced by vasomodulators in kidneys, livers, muscles, and implanted tumors in rats as measured by dynamic Gd-DTPA-enhanced MRI.
    Magnetic resonance in medicine, 1996, Volume: 36, Issue:6

    Topics: Adenocarcinoma; Angiotensin II; Animals; Blood Flow Velocity; Capillary Permeability; Cell Transplan

1996
Synthesis, biodistribution and imaging properties of indium-111-DTPA-paclitaxel in mice bearing mammary tumors.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Autoradiography; Chelating Agents; Female; Indium Radioi

1997
In vivo imaging of extraction fraction of low molecular weight MR contrast agents and perfusion rate in rodent tumors.
    Magnetic resonance in medicine, 1997, Volume: 38, Issue:2

    Topics: Adenocarcinoma; Animals; Capillary Permeability; Contrast Media; Deuterium Oxide; Evans Blue; Female

1997
Biodistribution and scintigraphy of [111In]DTPA-adriamycin in mammary tumor-bearing rats.
    Anti-cancer drugs, 1999, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents; Autoradiography; Doxorubicin; Female; Indium Radioisotopes; Inhibito

1999
Evaluation of In-111 DTPA-paclitaxel scintigraphy to predict response on murine tumors to paclitaxel.
    Annals of nuclear medicine, 1999, Volume: 13, Issue:3

    Topics: Animals; Carcinoma, Squamous Cell; Drug Resistance, Neoplasm; Female; Fibrosarcoma; Liver; Mammary N

1999
Effect of oral ZnDTPA on late effects of injected plutonium in rat.
    International journal of radiation biology, 1999, Volume: 75, Issue:8

    Topics: Administration, Oral; Animals; Bone and Bones; Bone Neoplasms; Glomerulosclerosis, Focal Segmental;

1999
Imaging tumor folate receptors using 111In-DTPA-methotrexate.
    Cancer biotherapy & radiopharmaceuticals, 1998, Volume: 13, Issue:3

    Topics: Animals; Autoradiography; Carrier Proteins; Drug Stability; Female; Folate Receptors, GPI-Anchored;

1998
[The effect of Ca-diethylenetriamine pentaacetate on the bio-behavior of tumor-affine metal complexes].
    Nuklearmedizin. Nuclear medicine, 1992, Volume: 31, Issue:6

    Topics: Animals; Calcium; Male; Mammary Neoplasms, Experimental; Mice; Neoplasm Transplantation; Pentetic Ac

1992
Effects of glutathione and ethylxanthate on mitomycin C activation by isolated rat hepatic or EMT6 mouse mammary tumor nuclei.
    Cancer research, 1985, Volume: 45, Issue:9

    Topics: Animals; Biotransformation; Cell Nucleus; Dicumarol; Edetic Acid; Glutathione; Hot Temperature; In V

1985
Dynamic (18F)-2-fluoro-2-deoxy-D-glucose (FDG) scintigraphy of normal and tumor-bearing rats.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1986, Volume: 186, Issue:4

    Topics: Animals; Brain; Deoxy Sugars; Deoxyglucose; Female; Fluorodeoxyglucose F18; Half-Life; Heart; Kidney

1986
Dual-contrast MR imaging of liver cancer in rats.
    AJR. American journal of roentgenology, 1988, Volume: 150, Issue:3

    Topics: Animals; Disease Models, Animal; Female; Ferric Compounds; Gadolinium; Gadolinium DTPA; Liver Neopla

1988
Dynamic spin-echo MRI of liver cancer using Gadolinium-DTPA: animal investigation.
    AJR. American journal of roentgenology, 1986, Volume: 147, Issue:2

    Topics: Adenocarcinoma; Animals; Contrast Media; Female; Liver Neoplasms; Magnetic Resonance Spectroscopy; M

1986