pentetic acid has been researched along with Disease Models, Animal in 81 studies
Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Injection of 1 mg of intravitreal triamcinolone acetonide at the time of cell injection significantly reduced both BRB breakdown and the incidence of eventual traction retinal detachment." | 3.69 | Localization and quantitation of blood-retinal barrier breakdown in experimental proliferative vitreoretinopathy. ( Ando, N; Berkowitz, BA; de Juan, E; Sen, HA; Wilson, CA, 1994) |
| "Using RG-C6 glioma-transplanted rats, we studied precontrast and postcontrast magnetic resonance imaging, extravasation of Evans blue, and histology." | 3.68 | Magnetic resonance imaging of experimental rat brain tumors: histopathological evaluation. ( Baba, T; Fukui, M; Inoue, T; Katsuki, C; Moriguchi, M; Natori, Y, 1990) |
| "Cardiotoxicity was confirmed by gamma imaging and scintillation counting (1." | 1.51 | Imaging doxorubicin and polymer-drug conjugates of doxorubicin-induced cardiotoxicity with bispecific anti-myosin-anti-DTPA antibody and Tc-99m-labeled polymers. ( Bhattarai, P; Gada, K; Khaw, BA; Majewski, S; Panwar, R; Patil, V, 2019) |
| "Rats underwent a 1-h middle cerebral artery occlusion followed by reperfusion." | 1.43 | Single photon emission computed tomography imaging of cerebral blood flow, blood-brain barrier disruption, and apoptosis time course after focal cerebral ischemia in rats. ( Bucci, C; Dignat-George, F; Filannino, MA; Garrigue, P; Giacomino, L; Guillet, B; Muzio, V; Pisano, P; Sabatier, F, 2016) |
| "Animals with Dominant Pattern F0-F1 liver fibrosis (D(-)=39) demonstrated significantly (P<0." | 1.43 | Staging of fibrosis in experimental non-alcoholic steatohepatitis by quantitative molecular imaging in rat models. ( Behling, CA; Brenner, DA; Farshchi-Heydari, S; Hoh, CK; Loomba, R; Mattrey, RF; Schnabl, B; Sirlin, CB; Vera, DR, 2016) |
| " Additionally, the in vivo biodistribution study clearly identified accumulations of G-CSF in the heart, liver, bone marrow, and urinary bladder, an indication of systemic absorption of G-CSF; its relative bioavailability was approximately 13." | 1.40 | Treatment of chemotherapy-induced neutropenia in a rat model by using multiple daily doses of oral administration of G-CSF-containing nanoparticles. ( Chen, CT; Chou, YC; Chuang, EY; Lin, KJ; Lin, PY; Mi, FL; Su, FY; Sung, HW; Wey, SP; Yen, TC, 2014) |
| "Brain tumors were induced in Balb/c mice via intracranial injection of Lewis Lung carcinoma cells into the right hemisphere of the mouse brain using stereotaxic apparatus." | 1.39 | Examination of blood-brain barrier (BBB) integrity in a mouse brain tumor model. ( Bachmeier, CJ; Hatch, GM; Miller, DW; Mitchell, R; On, NH; Savant, SD, 2013) |
| "Injury volume during middle cerebral artery occlusion did not predict histological outcome at 2 weeks." | 1.37 | Magnetic resonance imaging (MRI) as a translational tool for the study of neonatal stroke. ( Derugin, N; Dzietko, M; Ferriero, DM; Vexler, ZS; Wendland, M, 2011) |
| "Brain edema in gliomas is an epiphenomenon related to blood-brain-barrier (BBB) breakdown in which endothelial nitric oxide synthase (eNOS) plays a key role." | 1.36 | The role of eNOS in vascular permeability in ENU-induced gliomas. ( Argandoña, EG; Bengoetxea, H; Bulnes, S; Lafuente, JV; Leis, O; Ortuzar, N, 2010) |
| "Myocardial infarcts were generated by occluding the Left Anterior Descending (LAD) coronary artery with an angioplasty balloon for 180 min, and four weeks later occluding the Left Circumflex (LCx) coronary artery for 180 min." | 1.36 | Differentiation of acute and four-week old myocardial infarct with Gd(ABE-DTTA)-enhanced CMR. ( Baker, R; Brott, BC; Elgavish, A; Elgavish, GA; Kirschner, R; Kiss, P; Litovsky, S; Ruzsics, B; Simor, T; Suranyi, P; Toth, A; Toth, L; Varga-Szemes, A, 2010) |
| "Malignant carcinoid tumors express high numbers of somatostatin receptors." | 1.32 | GOT1 xenografted to nude mice: a unique model for in vivo studies on SSTR-mediated radiation therapy of carcinoid tumors. ( Ahlman, H; Bernhardt, P; Forssell-Aronsson, E; Johanson, V; Kölby, L; Nilsson, O, 2004) |
| " Using a single injection of a novel, long half-life intravascular magnetopharmaceutical with a high tissue:blood susceptibility difference (deltachi) to deltaR1 ratio, changes in tissue transverse relaxivity (deltaR2 or deltaR2*) that arise from changes in blood volume were measured, while preserving the ability to measure blood flow using traditional T1-based ASL techniques." | 1.30 | Continuous assessment of perfusion by tagging including volume and water extraction (CAPTIVE): a steady-state contrast agent technique for measuring blood flow, relative blood volume fraction, and the water extraction fraction. ( Bogdanov, AA; Jenkins, BG; Kwong, KK; Marota, JJ; Rosen, BR; Shimizu-Sasamata, M; Weisskoff, RM; Weissleder, R; Zaharchuk, G, 1998) |
| "Hemoglobin (Hb) is a toxic molecule responsible for the extreme lethality associated with experimental Escherichia coli peritonitis, but the mechanism has yet to be elucidated." | 1.30 | Hemoglobin toxicity in experimental bacterial peritonitis is due to production of reactive oxygen species. ( Han, JA; Kim, KM; Kim, SS; Kim, YM; Lea, HZ; Yoo, YM, 1999) |
| "Myocardial infarction was induced in 5 pigs." | 1.29 | MR imaging of double-contrast enhanced porcine myocardial infarction. Correlation with microdialysis. ( Ericsson, A; Hemmingsson, A; Nilsson, S; Oksendal, A; Waldenström, A; Wikström, G; Wikström, M, 1995) |
| "Myocardial infarction was induced in 12 pigs and Dy-DTPA-BMA (1." | 1.29 | Dy-DTPA-BMA as an indicator of tissue viability in MR imaging. An experimental study in the pig. ( Ericsson, A; Hemmingsson, A; Martinussen, HJ; Nilsson, S; Oksendal, AN; Waldenström, A; Wikström, G; Wikström, M, 1995) |
| "Contrast enhancement in the disk and scar tissue was measured and conspicuousness of the disk fragments assessed." | 1.29 | Utility of high-dose contrast enhancement for detecting recurrent herniated intervertebral disks. ( An, H; Hasegawa, T; Haughton, VM; Ho, KC; Nguyen, C, 1994) |
| "Myocardial infarctions were induced in 12 pigs to investigate whether a double-contrast method, combining a positive and a negative MR contrast agent, could improve the visualization of reperfused myocardial infarctions." | 1.29 | Double-contrast MR imaging of reperfused porcine myocardial infarction. An experimental study using Gd-DTAA and Dy-DTPA-BMA. ( Ericsson, A; Hemmingsson, A; Nilsson, S; Oksendal, A; Waldenström, A; Wikström, G; Wikström, M, 1996) |
| "MR images depict acute pulmonary embolism at the segmental and lobar levels with reasonable accuracy." | 1.29 | Magnetic resonance detection of acute pulmonary emboli in a canine model with pathologic correlation. ( Bergin, CJ; Bloor, C; Buxton, R; Hauschildt, J; Huynh, TV; Konopka, RG, 1996) |
| "Pneumocystis carinii pneumonia was induced by low protein diet and dexamethasone." | 1.28 | Imaging of Pneumocystis carinii pneumonia with 111In-labelled non-specific polyclonal IgG: an experimental study in rats. ( Callahan, R; Fischman, AJ; Fishman, JA; Khaw, BA; Nedelman, M; Rubin, RH; Strauss, HW, 1991) |
| "Although cadmium poisoning in humans is uncommon, there are reports of chronic cadmium poisoning in workmen and also in others in certain polluted areas." | 1.26 | Chelation of cadmium with BAL and DTPA in rats. ( Cherian, MG, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (12.35) | 18.7374 |
| 1990's | 30 (37.04) | 18.2507 |
| 2000's | 18 (22.22) | 29.6817 |
| 2010's | 22 (27.16) | 24.3611 |
| 2020's | 1 (1.23) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Panwar, R | 1 |
| Bhattarai, P | 1 |
| Patil, V | 1 |
| Gada, K | 1 |
| Majewski, S | 1 |
| Khaw, BA | 2 |
| Crosbie, DE | 1 |
| Keaney, J | 1 |
| Tam, LCS | 1 |
| Daniel Stamer, W | 1 |
| Campbell, M | 1 |
| Humphries, P | 1 |
| Joosten, L | 1 |
| Brom, M | 1 |
| Peeters, H | 1 |
| Bos, D | 1 |
| Himpe, E | 1 |
| Bouwens, L | 1 |
| Boerman, O | 1 |
| Gotthardt, M | 1 |
| Su, FY | 1 |
| Chuang, EY | 1 |
| Lin, PY | 1 |
| Chou, YC | 1 |
| Chen, CT | 1 |
| Mi, FL | 1 |
| Wey, SP | 1 |
| Yen, TC | 1 |
| Lin, KJ | 1 |
| Sung, HW | 1 |
| Griffiths, NM | 1 |
| Coudert, S | 1 |
| Wilk, JC | 1 |
| Renault, D | 1 |
| Angulo, JF | 1 |
| Van der Meeren, A | 1 |
| Pool, SE | 1 |
| Kam, BL | 1 |
| Koning, GA | 1 |
| Konijnenberg, M | 1 |
| Ten Hagen, TL | 1 |
| Breeman, WA | 1 |
| Krenning, EP | 1 |
| de Jong, M | 1 |
| van Eijck, CH | 1 |
| Kwong, JM | 1 |
| Hoang, C | 1 |
| Dukes, RT | 1 |
| Yee, RW | 1 |
| Gray, BD | 1 |
| Pak, KY | 1 |
| Caprioli, J | 1 |
| Rotman, M | 1 |
| Welling, MM | 1 |
| van den Boogaard, ML | 1 |
| Moursel, LG | 1 |
| van der Graaf, LM | 1 |
| van Buchem, MA | 1 |
| van der Maarel, SM | 1 |
| van der Weerd, L | 1 |
| van der Geest, T | 1 |
| Laverman, P | 1 |
| Gerrits, D | 1 |
| Franssen, GM | 1 |
| Metselaar, JM | 1 |
| Storm, G | 2 |
| Boerman, OC | 2 |
| Garrigue, P | 1 |
| Giacomino, L | 1 |
| Bucci, C | 1 |
| Muzio, V | 1 |
| Filannino, MA | 1 |
| Sabatier, F | 1 |
| Dignat-George, F | 1 |
| Pisano, P | 1 |
| Guillet, B | 1 |
| Schnabl, B | 1 |
| Farshchi-Heydari, S | 1 |
| Loomba, R | 1 |
| Mattrey, RF | 1 |
| Hoh, CK | 2 |
| Sirlin, CB | 1 |
| Brenner, DA | 1 |
| Behling, CA | 1 |
| Vera, DR | 2 |
| Stammes, MA | 1 |
| Knol-Blankevoort, VT | 1 |
| Cruz, LJ | 1 |
| Feitsma, HR | 1 |
| Mezzanotte, L | 1 |
| Cordfunke, RA | 1 |
| Sinisi, R | 1 |
| Dubikovskaya, EA | 1 |
| Maeda, A | 1 |
| DaCosta, RS | 1 |
| Bierau, K | 1 |
| Chan, A | 1 |
| Kaijzel, EL | 1 |
| Snoeks, TJ | 1 |
| van Beek, ER | 1 |
| Löwik, CW | 1 |
| Ruzsics, B | 3 |
| Surányi, P | 4 |
| Kiss, P | 4 |
| Brott, BC | 3 |
| Elgavish, A | 4 |
| Simor, T | 4 |
| Elgavish, GA | 4 |
| Eltoum, IE | 1 |
| Zeng, H | 1 |
| Spuentrup, E | 1 |
| Ruhl, KM | 1 |
| Botnar, RM | 1 |
| Wiethoff, AJ | 1 |
| Buhl, A | 1 |
| Jacques, V | 1 |
| Greenfield, MT | 1 |
| Krombach, GA | 1 |
| Günther, RW | 3 |
| Vangel, MG | 1 |
| Caravan, P | 1 |
| Ho, CL | 1 |
| Chen, LC | 1 |
| Lee, WC | 1 |
| Chiu, SP | 1 |
| Hsu, WC | 1 |
| Wu, YH | 1 |
| Yeh, CH | 1 |
| Stabin, MG | 1 |
| Jan, ML | 1 |
| Lin, WJ | 1 |
| Lee, TW | 2 |
| Chang, CH | 1 |
| Bulnes, S | 1 |
| Argandoña, EG | 1 |
| Bengoetxea, H | 1 |
| Leis, O | 1 |
| Ortuzar, N | 1 |
| Lafuente, JV | 1 |
| Kirschner, R | 2 |
| Toth, L | 1 |
| Varga-Szemes, A | 2 |
| Toth, A | 1 |
| Baker, R | 1 |
| Litovsky, S | 1 |
| Orestes, P | 1 |
| Bojadzic, D | 1 |
| Lee, J | 1 |
| Leach, E | 1 |
| Salajegheh, R | 1 |
| Digruccio, MR | 1 |
| Nelson, MT | 1 |
| Todorovic, SM | 1 |
| Dzietko, M | 1 |
| Wendland, M | 1 |
| Derugin, N | 1 |
| Ferriero, DM | 1 |
| Vexler, ZS | 1 |
| Essler, M | 1 |
| Gärtner, FC | 1 |
| Neff, F | 1 |
| Blechert, B | 1 |
| Senekowitsch-Schmidtke, R | 1 |
| Bruchertseifer, F | 1 |
| Morgenstern, A | 1 |
| Seidl, C | 1 |
| Wu, MC | 1 |
| Ho, HI | 1 |
| Wu, HL | 1 |
| Lo, JM | 1 |
| Kullgren, B | 1 |
| Jarvis, EE | 1 |
| An, DD | 1 |
| Abergel, RJ | 1 |
| On, NH | 1 |
| Mitchell, R | 1 |
| Savant, SD | 1 |
| Bachmeier, CJ | 1 |
| Hatch, GM | 1 |
| Miller, DW | 1 |
| Mishra, AK | 1 |
| Iznaga-Escobar, N | 1 |
| Figueredo, R | 1 |
| Jain, VK | 1 |
| Dwarakanath, BS | 1 |
| Pérez-Rodríguez, R | 1 |
| Sharma, RK | 1 |
| Mathew, TL | 1 |
| Mayers, I | 1 |
| Hurst, T | 1 |
| Radomski, A | 1 |
| Johnson, D | 1 |
| Fricker, S | 1 |
| Bridger, G | 1 |
| Cameron, B | 1 |
| Darkes, M | 1 |
| Radomski, MW | 1 |
| Nilsson, O | 2 |
| Kölby, L | 2 |
| Bernhardt, P | 2 |
| Forssell-Aronsson, E | 2 |
| Johanson, V | 1 |
| Ahlman, H | 2 |
| Ellner, SJ | 1 |
| Méndez, J | 1 |
| Ashburn, WL | 1 |
| Wallace, AM | 1 |
| Barber, PA | 1 |
| Foniok, T | 1 |
| Kirk, D | 1 |
| Buchan, AM | 1 |
| Laurent, S | 2 |
| Boutry, S | 1 |
| Muller, RN | 2 |
| Hoyte, L | 1 |
| Tomanek, B | 1 |
| Tuor, UI | 1 |
| Paulos, CM | 1 |
| Reddy, JA | 1 |
| Leamon, CP | 1 |
| Turk, MJ | 1 |
| Low, PS | 1 |
| Schmitt, A | 1 |
| Hutchings, SR | 1 |
| Song, D | 1 |
| Fricker, SP | 1 |
| Pang, CC | 1 |
| Yasuda, S | 1 |
| Ikuta, K | 1 |
| Uwatoku, T | 1 |
| Oi, K | 1 |
| Abe, K | 1 |
| Hyodo, F | 1 |
| Yoshimitsu, K | 1 |
| Sugimura, K | 1 |
| Utsumi, H | 1 |
| Katayama, Y | 1 |
| Shimokawa, H | 1 |
| Burtea, C | 1 |
| Murariu, O | 1 |
| Rattat, D | 1 |
| Toubeau, G | 1 |
| Verbruggen, A | 1 |
| Vansthertem, D | 1 |
| Vander Elst, L | 1 |
| Svesnikov, AA | 1 |
| Kramer, GM | 1 |
| Smotrova, LA | 1 |
| Mingazova, NB | 1 |
| Dormehl, IC | 1 |
| Jacobs, DJ | 1 |
| du Plessis, M | 1 |
| van der Watt, JJ | 1 |
| du Plessis, DJ | 1 |
| Bornmann, M | 1 |
| Lohse, JR | 1 |
| Shore, RM | 1 |
| Belzer, FO | 1 |
| Cherian, MG | 1 |
| Gupta, H | 1 |
| Wilkinson, RA | 1 |
| Bogdanov, AA | 2 |
| Callahan, RJ | 1 |
| Weissleder, R | 3 |
| Guy, J | 3 |
| McGorray, S | 2 |
| Qi, X | 1 |
| Fitzsimmons, J | 3 |
| Mancuso, A | 3 |
| Rao, N | 1 |
| Chung, YL | 1 |
| Williams, A | 1 |
| Beech, JS | 1 |
| Williams, SC | 1 |
| Bell, JD | 1 |
| Cox, IJ | 1 |
| Hope, J | 1 |
| Nilsson, S | 4 |
| Wikström, M | 4 |
| Ericsson, A | 4 |
| Wikström, G | 4 |
| Waldenström, A | 4 |
| Oksendal, A | 3 |
| Hemmingsson, A | 4 |
| Martinussen, HJ | 1 |
| Oksendal, AN | 1 |
| Stradling, GN | 1 |
| Gray, SA | 1 |
| Pearce, MJ | 1 |
| Wilson, I | 1 |
| Moody, JC | 1 |
| Burgada, R | 1 |
| Durbin, PW | 1 |
| Raymond, KN | 1 |
| Ibrahim, MA | 1 |
| Haughton, VM | 3 |
| Hyde, JS | 1 |
| Müller, TB | 1 |
| Haraldseth, O | 1 |
| Jones, RA | 1 |
| Sebastiani, G | 1 |
| Godtliebsen, F | 1 |
| Lindboe, CF | 1 |
| Unsgård, G | 1 |
| Reith, W | 2 |
| Forsting, M | 2 |
| Vogler, H | 1 |
| Heiland, S | 1 |
| Sartor, K | 2 |
| Nguyen, C | 2 |
| An, H | 1 |
| Ho, KC | 2 |
| Hasegawa, T | 1 |
| Beck, B | 1 |
| Rao, NA | 1 |
| Hamed, L | 1 |
| Dörfler, A | 1 |
| Meyding-Lamadé, U | 1 |
| Ando, N | 1 |
| Sen, HA | 1 |
| Berkowitz, BA | 1 |
| Wilson, CA | 1 |
| de Juan, E | 1 |
| Molina, L | 1 |
| Studenberg, S | 1 |
| Wolberg, G | 1 |
| Kazmierski, W | 1 |
| Wilson, J | 1 |
| Tadepalli, A | 1 |
| Chang, AC | 1 |
| Kosanke, S | 1 |
| Hinshaw, L | 1 |
| Vexler, VS | 2 |
| Roberts, TP | 1 |
| Rosenau, W | 1 |
| Nolte-Ernsting, CC | 1 |
| Adam, G | 2 |
| Bühne, M | 2 |
| Prescher, A | 2 |
| Huynh, TV | 1 |
| Bergin, CJ | 1 |
| Hauschildt, J | 1 |
| Konopka, RG | 1 |
| Bloor, C | 1 |
| Buxton, R | 1 |
| Alhassan, A | 1 |
| Weinmann, HJ | 1 |
| Zaharchuk, G | 1 |
| Marota, JJ | 1 |
| Shimizu-Sasamata, M | 1 |
| Weisskoff, RM | 1 |
| Kwong, KK | 1 |
| Jenkins, BG | 1 |
| Rosen, BR | 1 |
| Corvo, ML | 1 |
| Oyen, WJ | 1 |
| Van Bloois, L | 1 |
| Cruz, ME | 1 |
| Crommelin, DJ | 1 |
| Yoo, YM | 1 |
| Kim, KM | 1 |
| Kim, SS | 1 |
| Han, JA | 1 |
| Lea, HZ | 1 |
| Kim, YM | 1 |
| Tahtis, K | 1 |
| Lee, FT | 1 |
| Smyth, FE | 1 |
| Power, BE | 1 |
| Renner, C | 1 |
| Brechbiel, MW | 1 |
| Old, LJ | 1 |
| Hudson, PJ | 1 |
| Scott, AM | 1 |
| Chen, XG | 1 |
| Li, Y | 1 |
| Yan, CH | 1 |
| Li, LN | 1 |
| Han, R | 1 |
| Capani, F | 1 |
| Loidl, CF | 1 |
| Aguirre, F | 1 |
| Piehl, L | 1 |
| Facorro, G | 1 |
| Hager, A | 1 |
| De Paoli, T | 1 |
| Farach, H | 1 |
| Pecci-Saavedra, J | 1 |
| Rogers, BE | 1 |
| Zinn, KR | 1 |
| Lin, CY | 1 |
| Chaudhuri, TR | 1 |
| Buchsbaum, DJ | 1 |
| Chan, KH | 1 |
| Swarts, JD | 1 |
| Hashida, Y | 1 |
| Doyle, WJ | 1 |
| Kardatzke, D | 1 |
| Wolf, GL | 1 |
| Nolte-Ernsting, C | 1 |
| Bohndorf, K | 1 |
| Brasch, RC | 1 |
| Berthezene, Y | 1 |
| Moseley, M | 1 |
| Clément, O | 1 |
| Muehler, A | 1 |
| Price, D | 1 |
| Jerome, H | 1 |
| Fishman, JA | 1 |
| Strauss, HW | 1 |
| Fischman, AJ | 1 |
| Nedelman, M | 1 |
| Callahan, R | 1 |
| Rubin, RH | 1 |
| Baba, T | 1 |
| Moriguchi, M | 1 |
| Natori, Y | 1 |
| Katsuki, C | 1 |
| Inoue, T | 1 |
| Fukui, M | 1 |
| Sether, LA | 1 |
| Yu, SN | 1 |
| Biller, DS | 1 |
| Strandt, JA | 1 |
| Eurell, JC | 1 |
| Ellis, EA | 1 |
| Miller, DD | 1 |
| Holmvang, G | 1 |
| Gill, JB | 1 |
| Dragotakes, D | 1 |
| Kantor, HL | 1 |
| Okada, RD | 1 |
| Brady, TJ | 1 |
| Berry, I | 1 |
| Brant-Zawadzki, M | 1 |
| Manelfe, C | 1 |
| Saini, S | 1 |
| Stark, DD | 1 |
| Wittenberg, J | 1 |
| Ferrucci, JT | 1 |
| Royston, D | 2 |
| Fleming, JS | 1 |
| Krausz, T | 1 |
| Minty, BD | 1 |
| Naber, KG | 1 |
| Madsen, PO | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 1, Single Dose, Open-Label Study to Investigate the Safety and Efficacy of OTL38 Injection for Intraoperative Imaging of Folate Receptor-alpha Positive Pituitary Adenoma[NCT02629549] | Phase 1 | 33 participants (Actual) | Interventional | 2015-10-31 | Terminated (stopped due to Recruitment Fulfilled) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
81 other studies available for pentetic acid and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Imaging doxorubicin and polymer-drug conjugates of doxorubicin-induced cardiotoxicity with bispecific anti-myosin-anti-DTPA antibody and Tc-99m-labeled polymers.
Topics: Animals; Antibiotics, Antineoplastic; Antibodies, Bispecific; Cardiotoxicity; Disease Models, Animal | 2019 |
Age-related changes in eye morphology and aqueous humor dynamics in DBA/2J mice using contrast-enhanced ocular MRI.
Topics: Administration, Topical; Age Factors; Animals; Aqueous Humor; Contrast Media; Disease Models, Animal | 2019 |
Measuring the Pancreatic β Cell Mass in Vivo with Exendin SPECT during Hyperglycemia and Severe Insulitis.
Topics: Animals; Autoradiography; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Hyperglycemia; | 2019 |
Treatment of chemotherapy-induced neutropenia in a rat model by using multiple daily doses of oral administration of G-CSF-containing nanoparticles.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Chitosan; Disease Models, Animal; Dose-Respons | 2014 |
Combined drug and surgery treatment of plutonium-contaminated wounds: indications obtained using a rodent model.
Topics: Animals; Disease Models, Animal; Histones; Male; Pentetic Acid; Phosphoproteins; Plutonium; Radioact | 2014 |
[(111)In-DTPA]octreotide tumor uptake in GEPNET liver metastases after intra-arterial administration: an overview of preclinical and clinical observations and implications for tumor radiation dose after peptide radionuclide therapy.
Topics: Adult; Animals; Disease Models, Animal; Female; Humans; Indium Radioisotopes; Infusions, Intra-Arter | 2014 |
Bis(zinc-dipicolylamine), Zn-DPA, a new marker for apoptosis.
Topics: Animals; Apoptosis; Cell Count; Disease Models, Animal; Follow-Up Studies; Immunohistochemistry; In | 2014 |
Fusion of hIgG1-Fc to 111In-anti-amyloid single domain antibody fragment VHH-pa2H prolongs blood residential time in APP/PS1 mice but does not increase brain uptake.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Blood-Brain Barri | 2015 |
Comparison of three remote radiolabelling methods for long-circulating liposomes.
Topics: Animals; Contrast Media; Disease Models, Animal; Female; Humans; Indium; Indium Radioisotopes; Isoto | 2015 |
Single photon emission computed tomography imaging of cerebral blood flow, blood-brain barrier disruption, and apoptosis time course after focal cerebral ischemia in rats.
Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain; Brain Ischemia; Cerebrovascular Circulation; Disease | 2016 |
Staging of fibrosis in experimental non-alcoholic steatohepatitis by quantitative molecular imaging in rat models.
Topics: Animals; Disease Models, Animal; Gallium Radioisotopes; Humans; Kinetics; Liver Cirrhosis; Male; Mol | 2016 |
Pre-clinical Evaluation of a Cyanine-Based SPECT Probe for Multimodal Tumor Necrosis Imaging.
Topics: Animals; Carbocyanines; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Indium Radioisotop | 2016 |
Head-to-head comparison between delayed enhancement and percent infarct mapping for assessment of myocardial infarct size in a canine model.
Topics: Analysis of Variance; Animals; Contrast Media; Disease Models, Animal; Dogs; Gadolinium DTPA; Image | 2008 |
Virtual in vivo biopsy map of early prostate neoplasm in TRAMP mice by MRI.
Topics: Adenocarcinoma; Animals; Biopsy; Contrast Media; Diagnosis, Differential; Disease Models, Animal; Di | 2009 |
Molecular magnetic resonance imaging of myocardial perfusion with EP-3600, a collagen-specific contrast agent: initial feasibility study in a swine model.
Topics: Animals; Artifacts; Collagen; Contrast Media; Coronary Circulation; Coronary Stenosis; Disease Model | 2009 |
Receptor-binding, biodistribution, dosimetry, and micro-SPECT/CT imaging of 111In-[DTPA(1), Lys(3), Tyr(4)]-bombesin analog in human prostate tumor-bearing mice.
Topics: Animals; Binding, Competitive; Bombesin; Cell Line, Tumor; Disease Models, Animal; Drug Stability; F | 2009 |
The role of eNOS in vascular permeability in ENU-induced gliomas.
Topics: Animals; Autoantigens; Brain Neoplasms; Capillary Permeability; Disease Models, Animal; Ethylnitroso | 2010 |
Differentiation of acute and four-week old myocardial infarct with Gd(ABE-DTTA)-enhanced CMR.
Topics: Animals; Contrast Media; Diagnosis, Differential; Disease Models, Animal; Dogs; Gadolinium DTPA; Mag | 2010 |
Free radical signalling underlies inhibition of CaV3.2 T-type calcium channels by nitrous oxide in the pain pathway.
Topics: Adrenochrome; Analgesics, Non-Narcotic; Animals; Calcium Channel Blockers; Calcium Channels, T-Type; | 2011 |
Acute infarct selective MRI contrast agent.
Topics: Animals; Contrast Media; Diagnosis, Differential; Disease Models, Animal; Dogs; Gadolinium DTPA; Mag | 2012 |
Magnetic resonance imaging (MRI) as a translational tool for the study of neonatal stroke.
Topics: Age Factors; Animals; Animals, Newborn; Diffusion Magnetic Resonance Imaging; Disease Models, Animal | 2011 |
Therapeutic efficacy and toxicity of 225Ac-labelled vs. 213Bi-labelled tumour-homing peptides in a preclinical mouse model of peritoneal carcinomatosis.
Topics: Actinium; Animals; Bismuth; Cell Line, Tumor; Disease Models, Animal; Heterocyclic Compounds, 1-Ring | 2012 |
In vivo examination of 111In-bis-5HT-DTPA to target myeloperoxidase in atherosclerotic ApoE knockout mice.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cell Line; Cell Survival; Disease Models, Animal | 2012 |
Actinide chelation: biodistribution and in vivo complex stability of the targeted metal ions.
Topics: Actinoid Series Elements; Animals; Chelating Agents; Disease Models, Animal; Female; Ligands; Mice; | 2013 |
Examination of blood-brain barrier (BBB) integrity in a mouse brain tumor model.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Aqueous Barrier; Brain; Brai | 2013 |
Preparation and comparative evaluation of 99mTc-labeled 2-iminothiolane modified antibodies and CITC-DTPA immunoconjugates of anti-EGF-receptor antibodies.
Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Breast Neoplasms; Central Nervo | 2002 |
Increased matrix metalloproteinase activity after canine cardiopulmonary bypass is suppressed by a nitric oxide scavenger.
Topics: Animals; Brain Chemistry; Cardiopulmonary Bypass; CD18 Antigens; Disease Models, Animal; Dogs; Drug | 2003 |
GOT1 xenografted to nude mice: a unique model for in vivo studies on SSTR-mediated radiation therapy of carcinoid tumors.
Topics: Animals; Carcinoid Tumor; Disease Models, Animal; Indium Radioisotopes; Mice; Mice, Nude; Neoplasm T | 2004 |
Sentinel lymph node mapping of the colon and stomach using lymphoseek in a pig model.
Topics: Animals; Colon; Colonic Neoplasms; Dextrans; Disease Models, Animal; Female; Lymphatic Metastasis; M | 2004 |
MR molecular imaging of early endothelial activation in focal ischemia.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Contrast Media; Disease Models, Animal; Endothelium, Vascu | 2004 |
Ligand binding and kinetics of folate receptor recycling in vivo: impact on receptor-mediated drug delivery.
Topics: Animals; Carrier Proteins; Disease Models, Animal; Endocytosis; Folate Receptors, GPI-Anchored; Foli | 2004 |
Differences in biodistribution between 99mTc-depreotide, 111In-DTPA-octreotide, and 177Lu-DOTA-Tyr3-octreotate in a small cell lung cancer animal model.
Topics: Animals; Carcinoma, Small Cell; Cell Line, Tumor; Disease Models, Animal; Humans; Indium Radioisotop | 2005 |
The ruthenium-based nitric oxide scavenger, AMD6221, augments cardiovascular responsiveness to noradrenaline in rats with streptozotocin-induced diabetes.
Topics: Animals; Blood Pressure; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Synergism; Fr | 2005 |
In vivo magnetic resonance imaging of atherosclerotic lesions with a newly developed Evans blue-DTPA-gadolinium contrast medium in apolipoprotein-E-deficient mice.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Contrast Media; Disease Models, Animal; Injectio | 2008 |
Molecular imaging of alpha v beta3 integrin expression in atherosclerotic plaques with a mimetic of RGD peptide grafted to Gd-DTPA.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Binding, Competitive; Contrast Media; Disease Mo | 2008 |
[Nuclear medical diagnosis in the treatment of Ilizarov's posttraumatic osteomyelitis].
Topics: Animals; Diphosphates; Disease Models, Animal; Dogs; Female; Leg Injuries; Male; Osteomyelitis; Pent | 1984 |
Standardization of radiorenography in dehydrated and rehydrated primates under laboratory conditions.
Topics: Animals; Animals, Laboratory; Cercopithecus; Dehydration; Disease Models, Animal; Drinking; Kidney; | 1983 |
Acute renal artery occlusion: the role of collateral circulation.
Topics: Acute Disease; Animals; Blood Pressure; Collateral Circulation; Creatinine; Disease Models, Animal; | 1982 |
Chelation of cadmium with BAL and DTPA in rats.
Topics: Animals; Cadmium Poisoning; Dimercaprol; Disease Models, Animal; Drug Therapy, Combination; Feces; K | 1980 |
Inflammation: imaging with methoxy poly(ethylene glycol)-poly-L-lysine-DTPA, a long-circulating graft copolymer.
Topics: Animals; Capillary Permeability; Contrast Media; Disease Models, Animal; Escherichia coli Infections | 1995 |
Conjugated deferoxamine reduces blood-brain barrier disruption in experimental optic neuritis.
Topics: Animals; Blood-Brain Barrier; Capillary Permeability; Deferoxamine; Disease Models, Animal; Encephal | 1994 |
MRI assessment of the blood-brain barrier in a hamster model of scrapie.
Topics: Animals; Blood-Brain Barrier; Cricetinae; Disease Models, Animal; Evaluation Studies as Topic; Gadol | 1995 |
MR imaging of double-contrast enhanced porcine myocardial infarction. Correlation with microdialysis.
Topics: Analysis of Variance; Animals; Contrast Media; Disease Models, Animal; Drug Interactions; Dysprosium | 1995 |
Dy-DTPA-BMA as an indicator of tissue viability in MR imaging. An experimental study in the pig.
Topics: Analysis of Variance; Animals; Contrast Media; Disease Models, Animal; Drug Evaluation, Preclinical; | 1995 |
Decorporation of thorium-228 from the rat by 3,4,3-LIHOPO and DTPA after simulated wound contamination.
Topics: Animals; Aza Compounds; Disease Models, Animal; Female; Injections, Intramuscular; Injections, Intra | 1995 |
Enhancement of intervertebral disks with gadolinium complexes: comparison of an ionic and a nonionic medium in an animal model.
Topics: Animals; Contrast Media; Diffusion; Disease Models, Animal; Drug Combinations; Female; Gadolinium; G | 1994 |
Combined perfusion and diffusion-weighted magnetic resonance imaging in a rat model of reversible middle cerebral artery occlusion.
Topics: Animals; Arterial Occlusive Diseases; Cerebral Arterial Diseases; Cerebrovascular Circulation; Contr | 1995 |
Early MR detection of experimentally induced cerebral ischemia using magnetic susceptibility contrast agents: comparison between gadopentetate dimeglumine and iron oxide particles.
Topics: Animals; Blood Volume; Brain Ischemia; Capillary Permeability; Cerebral Angiography; Cerebrovascular | 1995 |
Utility of high-dose contrast enhancement for detecting recurrent herniated intervertebral disks.
Topics: Animals; Cicatrix; Contrast Media; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; D | 1994 |
Reversals of blood-brain barrier disruption by catalase: a serial magnetic resonance imaging study of experimental optic neuritis.
Topics: Animals; Blood-Brain Barrier; Catalase; Contrast Media; Disease Models, Animal; Encephalomyelitis, A | 1994 |
MRI monitoring of experimental cerebral ischaemia: comparison of two models.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Cerebral Infarction; Contrast Media; Disease Mo | 1994 |
Localization and quantitation of blood-retinal barrier breakdown in experimental proliferative vitreoretinopathy.
Topics: Animals; Blood-Retinal Barrier; Cells, Cultured; Contrast Media; Disease Models, Animal; Eye Disease | 1994 |
Myocardial cell death in reperfused and nonreperfused myocardial infarctions. MR imaging with dysprosioum-DTPA-BMA in the pig.
Topics: Animals; Cell Death; Contrast Media; Disease Models, Animal; Drug Evaluation, Preclinical; Dysprosiu | 1996 |
Double-contrast MR imaging of reperfused porcine myocardial infarction. An experimental study using Gd-DTAA and Dy-DTPA-BMA.
Topics: Animals; Contrast Media; Disease Models, Animal; Drug Evaluation, Preclinical; Dysprosium; Female; G | 1996 |
Efficacy of treatment with the iron (III) complex of diethylenetriamine pentaacetic acid in mice and primates inoculated with live lethal dose 100 Escherichia coli.
Topics: Animals; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Free Radical Scaveng | 1996 |
Early detection of acute tubular injury with diffusion-weighted magnetic resonance imaging in a rat model of myohemoglobinuric acute renal failure.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Blood Urea Nitrogen; Contrast Media; Creatinine; | 1996 |
MRI of degenerative bone marrow lesions in experimental osteoarthritis of canine knee joints.
Topics: Animals; Bone Cysts; Bone Marrow; Contrast Media; Disease Models, Animal; Dogs; Gadolinium; Gadolini | 1996 |
Magnetic resonance detection of acute pulmonary emboli in a canine model with pathologic correlation.
Topics: Acute Disease; Angiography; Animals; Contrast Media; Disease Models, Animal; Dissection; Dogs; Drug | 1996 |
Potential neurotoxic effects of gadopentetate dimeglumine: clinical significance.
Topics: Age Factors; Animals; Blood-Brain Barrier; Brain; Child, Preschool; Contrast Media; Disease Models, | 1997 |
Continuous assessment of perfusion by tagging including volume and water extraction (CAPTIVE): a steady-state contrast agent technique for measuring blood flow, relative blood volume fraction, and the water extraction fraction.
Topics: Animals; Blood Flow Velocity; Blood Volume; Body Water; Brain; Brain Ischemia; Contrast Media; Disea | 1998 |
Intravenous administration of superoxide dismutase entrapped in long circulating liposomes. II. In vivo fate in a rat model of adjuvant arthritis.
Topics: Animals; Arthritis, Experimental; Disease Models, Animal; Drug Carriers; Foot; Heart; Indium Radiois | 1999 |
Hemoglobin toxicity in experimental bacterial peritonitis is due to production of reactive oxygen species.
Topics: Animals; Chelating Agents; Cyclic N-Oxides; Deferoxamine; Disease Models, Animal; Edetic Acid; Esche | 1999 |
Biodistribution properties of (111)indium-labeled C-functionalized trans-cyclohexyl diethylenetriaminepentaacetic acid humanized 3S193 diabody and F(ab')(2) constructs in a breast carcinoma xenograft model.
Topics: Animals; Antibodies, Monoclonal; Antibody Affinity; Breast Neoplasms; Disease Models, Animal; Female | 2001 |
Cancer chemopreventive activities of S-3-1, a synthetic derivative of danshinone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Benzofurans; Bep | 2001 |
Changes in reactive oxygen species (ROS) production in rat brain during global perinatal asphyxia: an ESR study.
Topics: Animals; Asphyxia Neonatorum; Brain Chemistry; Chelating Agents; Cyclic N-Oxides; Disease Models, An | 2001 |
Targeted radiotherapy with [(90)Y]-SMT 487 in mice bearing human nonsmall cell lung tumor xenografts induced to express human somatostatin receptor subtype 2 with an adenoviral vector.
Topics: Adenoviridae; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal | 2002 |
Experimental otitis media evaluated by magnetic resonance imaging: an in vivo model.
Topics: Animals; Cats; Chinchilla; Contrast Media; Disease Models, Animal; Female; Gadolinium DTPA; Magnetic | 1992 |
Stability of osteochondral fragments of the femoral condyle: magnetic resonance imaging with histopathologic correlation in an animal model.
Topics: Animals; Cartilage, Articular; Contrast Media; Disease Models, Animal; Dogs; Drug Combinations; Femo | 1991 |
Facilitated magnetic resonance imaging diagnosis of pulmonary disease using a macromolecular blood-pool contrast agent, polylysine-(Gd-DTPA)40.
Topics: Animals; Contrast Media; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Gadolinium; G | 1991 |
Imaging of Pneumocystis carinii pneumonia with 111In-labelled non-specific polyclonal IgG: an experimental study in rats.
Topics: Animals; Dexamethasone; Diet; Disease Models, Animal; Gallium Radioisotopes; Immunoglobulin G; Indiu | 1991 |
Magnetic resonance imaging of experimental rat brain tumors: histopathological evaluation.
Topics: Animals; Brain; Brain Neoplasms; Contrast Media; Disease Models, Animal; Evans Blue; Gadolinium DTPA | 1990 |
Canine intervertebral disks: correlation of anatomy and MR imaging.
Topics: Animals; Contrast Media; Disease Models, Animal; Dogs; Gadolinium; Gadolinium DTPA; Intervertebral D | 1990 |
Gadolinium-DTPA-enhanced magnetic resonance imaging in experimental optic neuritis.
Topics: Animals; Demyelinating Diseases; Disease Models, Animal; Gadolinium DTPA; Guinea Pigs; Image Enhance | 1990 |
MRI detection of myocardial perfusion changes by gadolinium-DTPA infusion during dipyridamole hyperemia.
Topics: Animals; Contrast Media; Coronary Circulation; Coronary Disease; Dipyridamole; Disease Models, Anima | 1989 |
MRI study of a feline model of acute cerebral ischaemia. Contribution of paramagnetic contrast media to the diagnosis.
Topics: Animals; Cats; Contrast Media; Disease Models, Animal; Gadolinium; Gadolinium DTPA; Ischemic Attack, | 1988 |
Dual-contrast MR imaging of liver cancer in rats.
Topics: Animals; Disease Models, Animal; Female; Ferric Compounds; Gadolinium; Gadolinium DTPA; Liver Neopla | 1988 |
The non-steroidal anti-inflammatory agent, indoprofen, does not protect against hydrochloric acid induced lung injury in the rat.
Topics: Acid-Base Equilibrium; Animals; Disease Models, Animal; Female; Indoprofen; Lipid Peroxides; Lung; P | 1986 |
Cigarette smoke induced changes in rat pulmonary clearance of 99mTcDTPA. A comparison of particulate and gas phases.
Topics: Animals; Carboxyhemoglobin; Disease Models, Animal; Filtration; Male; Pasteurella; Pentetic Acid; Ph | 1985 |
Renal function in chronic hydronephrosis with and without infection and the role of the lymphatics. An experimental study in dogs.
Topics: Animals; Chronic Disease; Disease Models, Animal; Dogs; Escherichia coli Infections; Glomerular Filt | 1974 |