Page last updated: 2024-10-26

pentetic acid and Cushing Syndrome

pentetic acid has been researched along with Cushing Syndrome in 11 studies

Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.

Cushing Syndrome: A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.

Research Excerpts

ExcerptRelevanceReference
"To assess the role of magnetic resonance imaging in the evaluation of adrenocorticotropic-hormone (ACTH)-producing pituitary adenomas, and the effect of intravenously administered gadolinium-diethylenetriaminepentaacetic acid (DTPA) on lesion/pituitary contrast, imaging was performed in 13 patients with clinical and chemical evidence of Cushing disease."3.67Pituitary adenomas in patients with Cushing disease: initial experience with Gd-DTPA-enhanced MR imaging. ( Cutler, GB; Doppman, JL; Dwyer, AJ; Frank, JA; Hickey, AM; Loriaux, DL; Oldfield, EH; Schiable, TF, 1987)
"ACTH-secreting tumors were localized in 13 patients and were occult in four."1.32The role of [(18)F]fluorodeoxyglucose positron emission tomography and [(111)In]-diethylenetriaminepentaacetate-D-Phe-pentetreotide scintigraphy in the localization of ectopic adrenocorticotropin-secreting tumors causing Cushing's syndrome. ( Carrasquillo, JA; Chen, CC; Ilias, I; Nieman, LK; Pacak, K; Whatley, M, 2004)
"Bronchial carcinoid tumors are neuroendocrine neoplasms capable of expressing somatostatin receptors and of secreting neuromediators such as ACTH and chromogranins."1.30Imaging of bronchial carcinoid tumors associated to Cushing syndrome with 111In-Octreoscan scintigraphy and immunoscintigraphy with anti-chromogranin monoclonal antibodies. Report of two cases. ( Carretta, A; Chiesa, G; Grossi, A; Magnani, P; Melloni, G; Songini, C; Zannini, P, 1997)
"Bronchial carcinoid tumor is the most frequent occult source of ectopic ACTH-dependent Cushing's syndrome, but its initial localization may be very difficult, as well as its postoperative follow-up."1.30Localization and postoperative follow-up of a bronchial carcinoid tumor causing Cushing's syndrome by 111In-DTPA labelled octreotide scintigraphy. ( Fernandez-Fernandez, F; Flores, L; Halperin, I; Lomeña, F; Manzanares, JM; Vilardell, E, 1997)
"Bronchial carcinoid (BC) is a rare etiology of Cushing syndrome, and difficulties in differential diagnosis with Cushing's disease are often present."1.30[Cushing's syndrome secondary to bronchial carcinoid tumor: contribution of gammagraphy with 111In-DTPA octreotide in the localization diagnosis]. ( Bittini Copano, A; Folqué Gómez, E; Lampreave Márquez, JL; León Atance, P; Moreno Esteban, B; Peña González, E, 1999)
"Occult pituitary adenomas are identified at autopsy in 3% to 27% of unselected asymptomatic patients."1.29Pituitary magnetic resonance imaging in normal human volunteers: occult adenomas in the general population. ( Doppman, JL; Hall, WA; Luciano, MG; Oldfield, EH; Patronas, NJ, 1994)
"Absolute temporal scotomas were an early finding."1.29Early diagnosis of Nelson's syndrome. ( Bonicki, W; Brzezińska, A; Brzeziński, J; Janik, J; Jeske, W; Kasperlik-Zaluska, AA; Makowska, A; Migdalska, B; Walecki, J, 1996)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's8 (72.73)18.2507
2000's2 (18.18)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Corsello, SM1
Fintini, D1
Lovicu, RM1
Paragliola, RM1
Rufini, V1
Simonetti, G1
Pontecorvi, A1
Pacak, K1
Ilias, I1
Chen, CC1
Carrasquillo, JA1
Whatley, M1
Nieman, LK1
Krenning, EP1
Kwekkeboom, DJ1
Oei, HY1
de Jong, RJ1
Dop, FJ1
de Herder, WW1
Reubi, JC1
Lamberts, SW1
Colombo, N1
Loli, P1
Vignati, F1
Scialfa, G1
Hall, WA1
Luciano, MG1
Doppman, JL2
Patronas, NJ1
Oldfield, EH2
Schild, H1
Strack, T1
Strunk, H1
Mildenberger, P1
Schrezenmeir, J1
Kahaly, G1
Beyer, J1
Kasperlik-Zaluska, AA1
Walecki, J1
Jeske, W1
Migdalska, B1
Janik, J1
Bonicki, W1
Brzeziński, J1
Makowska, A1
Brzezińska, A1
Carretta, A1
Chiesa, G1
Magnani, P1
Songini, C1
Melloni, G1
Zannini, P1
Grossi, A1
Fernandez-Fernandez, F1
Halperin, I1
Manzanares, JM1
Flores, L1
Lomeña, F1
Vilardell, E1
Peña González, E1
Lampreave Márquez, JL1
León Atance, P1
Moreno Esteban, B1
Bittini Copano, A1
Folqué Gómez, E1
Dwyer, AJ1
Frank, JA1
Hickey, AM1
Cutler, GB1
Loriaux, DL1
Schiable, TF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of the Posterior Septectomy and Stamm Approach to Endoscopic Pituitary Adenoma Resection: A Randomized, Single-blind Trial[NCT01689064]55 participants (Anticipated)Interventional2012-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

11 other studies available for pentetic acid and Cushing Syndrome

ArticleYear
Ectopic ACTH syndrome due to occult bronchial carcinoid.
    Clinical nuclear medicine, 2009, Volume: 34, Issue:7

    Topics: ACTH Syndrome, Ectopic; Adult; Bronchial Neoplasms; Carcinoid Tumor; Cushing Syndrome; Diagnosis, Di

2009
The role of [(18)F]fluorodeoxyglucose positron emission tomography and [(111)In]-diethylenetriaminepentaacetate-D-Phe-pentetreotide scintigraphy in the localization of ectopic adrenocorticotropin-secreting tumors causing Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:5

    Topics: ACTH Syndrome, Ectopic; Adult; Aged; Cushing Syndrome; Female; Fluorodeoxyglucose F18; Humans; Indiu

2004
Somatostatin receptor scintigraphy in carcinoids, gastrinomas and Cushing's syndrome.
    Digestion, 1994, Volume: 55 Suppl 3

    Topics: Carcinoid Tumor; Cushing Syndrome; Gastrinoma; Gastrointestinal Neoplasms; Humans; Indium Radioisoto

1994
MR of corticotropin-secreting pituitary microadenomas.
    AJNR. American journal of neuroradiology, 1994, Volume: 15, Issue:8

    Topics: Adenoma; Adolescent; Adrenocorticotropic Hormone; Adult; Contrast Media; Cushing Syndrome; Drug Comb

1994
Pituitary magnetic resonance imaging in normal human volunteers: occult adenomas in the general population.
    Annals of internal medicine, 1994, May-15, Volume: 120, Issue:10

    Topics: Adenoma; Adolescent; Adult; Contrast Media; Cushing Syndrome; Female; Gadolinium; Gadolinium DTPA; H

1994
[Selective blood sampling from the sinus petrosus inferior: a comparison of CRF and TRH stimulation].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1993, Volume: 158, Issue:1

    Topics: Adenoma; Adrenocorticotropic Hormone; Contrast Media; Corticotropin-Releasing Hormone; Cranial Sinus

1993
Early diagnosis of Nelson's syndrome.
    Journal of molecular neuroscience : MN, 1996,Summer, Volume: 7, Issue:2

    Topics: Adenoma; Adolescent; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Cortisone; Cushing Syndrome;

1996
Imaging of bronchial carcinoid tumors associated to Cushing syndrome with 111In-Octreoscan scintigraphy and immunoscintigraphy with anti-chromogranin monoclonal antibodies. Report of two cases.
    The Journal of cardiovascular surgery, 1997, Volume: 38, Issue:2

    Topics: Adolescent; Bronchial Neoplasms; Carcinoid Tumor; Chromogranin A; Chromogranins; Cushing Syndrome; F

1997
Localization and postoperative follow-up of a bronchial carcinoid tumor causing Cushing's syndrome by 111In-DTPA labelled octreotide scintigraphy.
    Journal of endocrinological investigation, 1997, Volume: 20, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Bronchial Neoplasms; Carcinoid Tumor; Cushing Syndrome; Dexameth

1997
[Cushing's syndrome secondary to bronchial carcinoid tumor: contribution of gammagraphy with 111In-DTPA octreotide in the localization diagnosis].
    Anales de medicina interna (Madrid, Spain : 1984), 1999, Volume: 16, Issue:11

    Topics: Aged; Bronchial Neoplasms; Carcinoid Tumor; Cushing Syndrome; Female; Humans; Male; Middle Aged; Oct

1999
Pituitary adenomas in patients with Cushing disease: initial experience with Gd-DTPA-enhanced MR imaging.
    Radiology, 1987, Volume: 163, Issue:2

    Topics: ACTH Syndrome, Ectopic; Adenoma; Contrast Media; Cushing Syndrome; Female; Gadolinium; Gadolinium DT

1987