pentetic acid has been researched along with Colonic Neoplasms in 40 studies
Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Monoclonal antibody 19-9 (mAb 19-9) against human colon adenocarcinoma was conjugated with gadolinium X diethylenetriaminepentaacetic acid (Gd X DTPA) and used as a contrast agent in nuclear magnetic resonance (NMR) in an effort to improve tumor target selectivity in nude mice." | 3.67 | Selective modification of NMR relaxation time in human colorectal carcinoma by using gadolinium-diethylenetriaminepentaacetic acid conjugated with monoclonal antibody 19-9. ( Bohy, J; Chatal, JF; Conti, ML; Curtet, C; Douillard, JY; Koprowski, H; Saccavini, JC; Tellier, C; Thedrez, P, 1986) |
| "The results also showed a good anticancer activity for 99mTc-DTPA-Methionine." | 1.39 | A comparative study of two novel nanosized radiolabeled analogues of methionine for SPECT tumor imaging. ( Aghasadeghi, MR; Alavidjeh, MS; Amanlou, M; Ardestani, MS; Daha, FJ; Ebrahimi, SE; Ghorbani, M; Khosroshahi, AG; Mousavi, L; Pouriayevali, MH; Sabzevari, O; Sadat, SM, 2013) |
| " A specific dose-response (P = 0." | 1.32 | Targeting of HER2 antigen for the treatment of disseminated peritoneal disease. ( Abdulla, A; Albert, PS; Brady, ED; Brechbiel, MW; Garmestani, K; Ma, D; Milenic, DE, 2004) |
| "Colon cancer is the second most common cause of cancer mortality." | 1.30 | Indium-111 satumomab pendetide: the first FDA-approved monoclonal antibody for tumor imaging. ( Bohdiewicz, PJ, 1998) |
| "Recurrent colorectal cancer is seen in as many as 40% of patients after curative resection." | 1.29 | In-111 CYT-103 monoclonal antibody imaging in patients with suspected recurrent colorectal cancer. ( Abdel-Nabi, H; Doerr, RJ; Herrera, L, 1993) |
| " The pilot clinical study of the 99mTc labelled anti melanoma Fab and 111-In-DTPA labelled anti melanoma F(ab')2 showed differences in the pharmacokinetic parameters." | 1.28 | Pharmacokinetics of radiopharmaceuticals. ( Jánoki, GA; Kerekes, A, 1992) |
| "Gadolinium was attached to antibodies and tested in vitro and in vivo for its effect on proton relaxation enhancement." | 1.27 | Magnetic resonance imaging using gadolinium labeled monoclonal antibody. ( Connett, JM; Murphy, WA; Neufeld, DM; Otsuka, FL; Philpott, GW; Totty, WG; Unger, EC; Welch, MS, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (20.00) | 18.7374 |
| 1990's | 18 (45.00) | 18.2507 |
| 2000's | 12 (30.00) | 29.6817 |
| 2010's | 2 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nichols, B | 1 |
| Qin, Z | 1 |
| Yang, J | 1 |
| Vera, DR | 3 |
| Devaraj, NK | 1 |
| Busse, F | 1 |
| Führer, D | 1 |
| Stumvoll, M | 1 |
| Schneider, JP | 1 |
| Neid, M | 1 |
| Kluge, R | 1 |
| Sterker, I | 1 |
| de Jong, GM | 1 |
| Boerman, OC | 1 |
| Heskamp, S | 1 |
| Aarts, F | 1 |
| Bleichrodt, RP | 1 |
| Hendriks, T | 1 |
| Khosroshahi, AG | 1 |
| Amanlou, M | 1 |
| Sabzevari, O | 1 |
| Daha, FJ | 1 |
| Aghasadeghi, MR | 1 |
| Ghorbani, M | 1 |
| Ardestani, MS | 1 |
| Alavidjeh, MS | 1 |
| Sadat, SM | 1 |
| Pouriayevali, MH | 1 |
| Mousavi, L | 1 |
| Ebrahimi, SE | 1 |
| Govindan, SV | 1 |
| Griffiths, GL | 2 |
| Michel, RB | 1 |
| Andrews, PM | 1 |
| Goldenberg, DM | 3 |
| Mattes, MJ | 1 |
| Mishra, AK | 1 |
| Iznaga-Escobar, N | 1 |
| Figueredo, R | 1 |
| Jain, VK | 1 |
| Dwarakanath, BS | 1 |
| Pérez-Rodríguez, R | 1 |
| Sharma, RK | 1 |
| Mathew, TL | 1 |
| Méndez, J | 2 |
| Wallace, AM | 2 |
| Hoh, CK | 2 |
| Ghavami, S | 1 |
| Kerkhoff, C | 1 |
| Los, M | 1 |
| Hashemi, M | 1 |
| Sorg, C | 1 |
| Karami-Tehrani, F | 1 |
| Ellner, SJ | 1 |
| Ashburn, WL | 1 |
| Milenic, DE | 4 |
| Garmestani, K | 2 |
| Brady, ED | 1 |
| Albert, PS | 1 |
| Ma, D | 2 |
| Abdulla, A | 1 |
| Brechbiel, MW | 6 |
| Chinn, PC | 1 |
| Morena, RA | 1 |
| Santoro, DA | 1 |
| Kazules, T | 1 |
| Kashmiri, SV | 1 |
| Schlom, J | 5 |
| Hanna, N | 1 |
| Braslawsky, G | 1 |
| Seshadri, M | 1 |
| Spernyak, JA | 1 |
| Maiery, PG | 1 |
| Cheney, RT | 1 |
| Mazurchuk, R | 1 |
| Bellnier, DA | 1 |
| Janssen, PJ | 1 |
| de Visser, M | 1 |
| Verwijnen, SM | 1 |
| Bernard, BF | 1 |
| Srinivasan, A | 1 |
| Erion, JL | 1 |
| Breeman, WA | 1 |
| Vulto, AG | 1 |
| Krenning, EP | 1 |
| de Jong, M | 1 |
| Carr, DH | 1 |
| Paik, CH | 1 |
| Ebbert, MA | 1 |
| Murphy, PR | 1 |
| Lassman, CR | 1 |
| Reba, RC | 1 |
| Eckelman, WC | 1 |
| Pak, KY | 1 |
| Powe, J | 1 |
| Steplewski, Z | 1 |
| Koprowski, H | 2 |
| Pieslor, PC | 1 |
| White, CA | 1 |
| Varney, RR | 1 |
| Göhr-Rosenthal, S | 1 |
| Schmitt-Willich, H | 1 |
| Ebert, W | 1 |
| Conrad, J | 1 |
| Vijayakumar, V | 1 |
| Blend, MJ | 1 |
| Johnson, DK | 2 |
| Seevers, RH | 1 |
| Schnobrich, KE | 1 |
| Bekerman, C | 1 |
| Doerr, RJ | 2 |
| Herrera, L | 1 |
| Abdel-Nabi, H | 2 |
| Gangopadhyay, A | 1 |
| Petrick, AT | 1 |
| Thomas, P | 1 |
| Alvarez-Diez, TM | 1 |
| Polihronis, J | 1 |
| Reilly, RM | 1 |
| Chinol, M | 1 |
| Paganelli, G | 1 |
| Sudati, F | 1 |
| Meares, C | 1 |
| Fazio, F | 1 |
| Luboldt, W | 1 |
| Bauerfeind, P | 1 |
| Steiner, P | 1 |
| Fried, M | 1 |
| Krestin, GP | 1 |
| Debatin, JF | 1 |
| Qiu, XB | 1 |
| Cadenas, E | 1 |
| Nakamoto, Y | 1 |
| Saga, T | 1 |
| Sakahara, H | 1 |
| Yao, Z | 1 |
| Zhang, M | 1 |
| Sato, N | 1 |
| Zhao, S | 1 |
| Nakada, H | 1 |
| Yamashina, I | 1 |
| Konishi, J | 1 |
| Bohdiewicz, PJ | 1 |
| Roselli, M | 2 |
| Mirzadeh, S | 2 |
| Pippin, CG | 2 |
| Gansow, OA | 4 |
| Colcher, D | 3 |
| Chappell, LL | 1 |
| Dadachova, E | 1 |
| Yordanov, A | 1 |
| Jánoki, GA | 1 |
| Kerekes, A | 1 |
| Bosslet, K | 1 |
| Steinstraesser, A | 1 |
| Hermentin, P | 1 |
| Kuhlmann, L | 1 |
| Bruynck, A | 1 |
| Magerstaedt, M | 1 |
| Seemann, G | 1 |
| Schwarz, A | 1 |
| Sedlacek, HH | 1 |
| Sharkey, RM | 2 |
| Motta-Hennessy, C | 2 |
| Fand, I | 1 |
| Jones, AL | 1 |
| Chan, HW | 1 |
| Balu, D | 1 |
| Schmelter, RF | 1 |
| Maguire, RT | 1 |
| Ogneva, TV | 1 |
| Carney, PL | 1 |
| Rogers, PE | 1 |
| Esteban, JM | 1 |
| Atcher, RW | 1 |
| Simpson, DE | 1 |
| Curtet, C | 1 |
| Tellier, C | 1 |
| Bohy, J | 1 |
| Conti, ML | 1 |
| Saccavini, JC | 1 |
| Thedrez, P | 1 |
| Douillard, JY | 1 |
| Chatal, JF | 1 |
| Jakowatz, JG | 1 |
| Beatty, BG | 1 |
| Vlahos, WG | 1 |
| Porudominsky, D | 1 |
| Philben, VJ | 1 |
| Williams, LE | 1 |
| Paxton, RJ | 1 |
| Shively, JE | 1 |
| Beatty, JD | 1 |
| Unger, EC | 1 |
| Totty, WG | 1 |
| Neufeld, DM | 1 |
| Otsuka, FL | 1 |
| Murphy, WA | 1 |
| Welch, MS | 1 |
| Connett, JM | 1 |
| Philpott, GW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 0 Trial of (111)Indium CHX-A DTPA Trastuzumab Imaging in Cancer[NCT01445054] | Early Phase 1 | 13 participants (Actual) | Interventional | 2007-03-01 | Terminated | ||
| An Open Label, Randomized, Phase II Study of AS1404 in Combination With Docetaxel in Patients With Hormone Refractory Metastatic Prostate Cancer[NCT00111618] | Phase 2 | 70 participants (Anticipated) | Interventional | 2005-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
40 other studies available for pentetic acid and Colonic Neoplasms
| Article | Year |
|---|---|
68Ga chelating bioorthogonal tetrazine polymers for the multistep labeling of cancer biomarkers.
Topics: Animals; Antibodies, Monoclonal; Biomarkers, Tumor; Chelating Agents; Colonic Neoplasms; Dextrans; G | 2014 |
Metastasis of neuroendocrine colon carcinoma mimicking Graves' ophthalmopathy.
Topics: Aged; Colonic Neoplasms; Diagnosis, Differential; Graves Ophthalmopathy; Humans; Indium Radioisotope | 2008 |
Radioimmunotherapy prevents local recurrence of colonic cancer in an experimental model.
Topics: Animals; Antibodies, Monoclonal; Body Weight; Cell Line, Tumor; Colonic Neoplasms; Lutetium; Male; N | 2009 |
A comparative study of two novel nanosized radiolabeled analogues of methionine for SPECT tumor imaging.
Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Colon; Colonic Neoplasms; Dendrimers; Humans; Methionine; | 2013 |
Use of galactosylated-streptavidin as a clearing agent with 111In-labeled, biotinylated antibodies to enhance tumor/non-tumor localization ratios.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, B-Lymphocyte; Biotinylatio | 2002 |
Preparation and comparative evaluation of 99mTc-labeled 2-iminothiolane modified antibodies and CITC-DTPA immunoconjugates of anti-EGF-receptor antibodies.
Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Breast Neoplasms; Central Nervo | 2002 |
Detection of gastric and colonic sentinel nodes through endoscopic administration of 99mTc-DTPA-mannosyl-dextran in pigs.
Topics: Animals; Colon; Colonic Neoplasms; Dextrans; Endoscopy, Gastrointestinal; Feasibility Studies; Gastr | 2003 |
Mechanism of apoptosis induced by S100A8/A9 in colon cancer cell lines: the role of ROS and the effect of metal ions.
Topics: Antioxidants; Apoptosis; Calgranulin A; Calgranulin B; Caspase 3; Caspase 9; Caspases; Chelating Age | 2004 |
Sentinel lymph node mapping of the colon and stomach using lymphoseek in a pig model.
Topics: Animals; Colon; Colonic Neoplasms; Dextrans; Disease Models, Animal; Female; Lymphatic Metastasis; M | 2004 |
Targeting of HER2 antigen for the treatment of disseminated peritoneal disease.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Colonic Neoplasms; Female; Human | 2004 |
Pharmacokinetics and tumor localization of (111)in-labeled HuCC49DeltaC(H)2 in BALB/c mice and athymic murine colon carcinoma xenograft.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Antigens, Neoplasm; Binding, Competitive; Col | 2006 |
Visualizing the acute effects of vascular-targeted therapy in vivo using intravital microscopy and magnetic resonance imaging: correlation with endothelial apoptosis, cytokine induction, and treatment outcome.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Capillary Permeability; Colonic Neoplasms | 2007 |
Five Stabilized 111In-labeled neurotensin analogs in nude mice bearing HT29 tumors.
Topics: Analysis of Variance; Animals; Colonic Neoplasms; Humans; Indium Radioisotopes; Kidney; Lysine; Male | 2007 |
The use of iron and gadolinium chelates as NMR contrast agents: animal and human studies.
Topics: Abdominal Neoplasms; Animals; Brain Neoplasms; Colonic Neoplasms; Contrast Media; Edetic Acid; Ferri | 1984 |
Factors influencing DTPA conjugation with antibodies by cyclic DTPA anhydride.
Topics: Animals; Antibodies; Antibodies, Monoclonal; Chemical Phenomena; Chemistry; Colonic Neoplasms; Elect | 1983 |
Splenic metastasis from colon carcinoma imaged using In-111 OncoScint.
Topics: Antibodies, Monoclonal; Colonic Neoplasms; Female; Humans; Indium Radioisotopes; Middle Aged; Oligop | 1995 |
The demonstration of human tumors on nude mice using gadolinium-labelled monoclonal antibodies for magnetic resonance imaging.
Topics: Animals; Antibodies, Monoclonal; Colonic Neoplasms; Gadolinium DTPA; Humans; Magnetic Resonance Imag | 1993 |
Improved detection of hepatic lesions using MoAb B72.3 and a modified 111In labelling technique in patients with recurrent colon cancer.
Topics: Adult; Aged; Colonic Neoplasms; Female; Humans; Indium Radioisotopes; Isotope Labeling; Liver Neopla | 1993 |
In-111 CYT-103 monoclonal antibody imaging in patients with suspected recurrent colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal; Carcinoembryonic Antigen; Colonic Neoplasms; Fe | 1993 |
Modification of antibody isoelectric point affects biodistribution of 111-indium-labeled antibody.
Topics: Animals; Colonic Neoplasms; Electrophoresis, Agar Gel; Humans; Immunoglobulin G; Indium Radioisotope | 1996 |
Pretargeted tumour imaging with streptavidin immunoconjugates of monoclonal antibody CC49 and 111In-DTPA-biocytin.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Bacterial Proteins; Colonic Neoplasms; Female; | 1996 |
Biodistribution in tumour-bearing mice of two 90Y-labelled biotins using three-step tumour targeting.
Topics: Adenocarcinoma; Animals; Avidin; Beta Particles; Biotin; Bone and Bones; Colonic Neoplasms; Humans; | 1997 |
Preliminary assessment of three-dimensional magnetic resonance imaging for various colonic disorders.
Topics: Aged; Aged, 80 and over; Colon; Colonic Diseases; Colonic Neoplasms; Colonic Polyps; Contrast Media; | 1997 |
The role of NAD(P)H:quinone oxidoreductase in quinone-mediated p21 induction in human colon carcinoma cells.
Topics: Acetylcysteine; Aziridines; Benzoquinones; Blotting, Northern; Cell Division; Colonic Neoplasms; Cyc | 1997 |
Three-step tumor imaging with biotinylated monoclonal antibody, streptavidin and 111In-DTPA-biotin.
Topics: Animals; Antibodies, Monoclonal; Biotin; Cell Line; Colonic Neoplasms; Female; Humans; Indium Radioi | 1998 |
Indium-111 satumomab pendetide: the first FDA-approved monoclonal antibody for tumor imaging.
Topics: Aged; Antibodies, Monoclonal; Clinical Trials as Topic; Colonic Neoplasms; Drug Approval; Female; Hu | 1998 |
In vivo comparison of CHX-DTPA ligand isomers in athymic mice bearing carcinoma xenografts.
Topics: Animals; Antibodies, Monoclonal; Colonic Neoplasms; Humans; Indium Radioisotopes; Isomerism; Isothio | 1999 |
In vivo comparison of macrocyclic and acyclic ligands for radiolabeling of monoclonal antibodies with 177Lu for radioimmunotherapeutic applications.
Topics: Adenocarcinoma; Aniline Compounds; Animals; Antibodies, Monoclonal; Colonic Neoplasms; Female; Heter | 2002 |
Pharmacokinetics of radiopharmaceuticals.
Topics: Animals; Antibodies, Monoclonal; Bile; Carcinoembryonic Antigen; Chromatography, High Pressure Liqui | 1992 |
Comparative biodistribution studies of DTPA-derivative bifunctional chelates for radiometal labeled monoclonal antibodies.
Topics: Animals; Antibodies, Monoclonal; Chelating Agents; Colonic Neoplasms; Indium Radioisotopes; Kidney; | 1991 |
Generation of bispecific monoclonal antibodies for two phase radioimmunotherapy.
Topics: Animals; Antibodies, Monoclonal; Colonic Neoplasms; Humans; Injections, Intravenous; Mice; Mice, Nud | 1991 |
Selection of a DTPA chelate conjugate for monoclonal antibody targeting to a human colonic tumor in nude mice.
Topics: Animals; Antibodies, Monoclonal; Autoradiography; Carcinoembryonic Antigen; Chelating Agents; Coloni | 1990 |
In-111-labeled monoclonal antibody immunoscintigraphy in colorectal carcinoma: safety, sensitivity, and preliminary clinical results.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antigens, Neoplasm; Colonic Neoplas | 1990 |
Metabolism of indium-111-labeled murine monoclonal antibody in tumor and normal tissue of the athymic mouse.
Topics: Animals; Antibodies, Monoclonal; Carcinoembryonic Antigen; Chromatography, High Pressure Liquid; Chr | 1990 |
[Clinical use of the Soviet nephrotropic drug 113mIn-pentaind].
Topics: Adult; Aged; Colonic Neoplasms; Female; Humans; Hypertension; Kidney; Kidney Function Tests; Male; M | 1985 |
Dual isotope study of iodine-125 and indium-111-labeled antibody in athymic mice.
Topics: Animals; Antibodies, Monoclonal; Colonic Neoplasms; Female; Humans; Indium Radioisotopes; Iodine Rad | 1989 |
New method for the chelation of indium-111 to monoclonal antibodies: biodistribution and imaging of athymic mice bearing human colon carcinoma xenografts.
Topics: Animals; Antibodies, Monoclonal; Colonic Neoplasms; Edetic Acid; Humans; Indium; Isotope Labeling; M | 1987 |
Selective modification of NMR relaxation time in human colorectal carcinoma by using gadolinium-diethylenetriaminepentaacetic acid conjugated with monoclonal antibody 19-9.
Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Colonic Neoplasms; Gadolinium | 1986 |
High-specific-activity 111In-labeled anticarcinoembryonic antigen monoclonal antibody: biodistribution and imaging in nude mice bearing human colon cancer xenografts.
Topics: Animals; Antibodies, Monoclonal; Carcinoembryonic Antigen; Colonic Neoplasms; Female; Humans; Indium | 1985 |
Magnetic resonance imaging using gadolinium labeled monoclonal antibody.
Topics: Animals; Antibodies, Monoclonal; Carcinoembryonic Antigen; Colonic Neoplasms; Cricetinae; Gadolinium | 1985 |