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pentetic acid and Cell Transformation, Neoplastic

pentetic acid has been researched along with Cell Transformation, Neoplastic in 14 studies

Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research Excerpts

ExcerptRelevanceReference
"Pretargeting prostate cancer with Bom-bsCx or Bom-bsFCx enabled fast delivery of high specific radioactivity ¹¹¹In- or ⁹⁹mTc-labeled polymer-drug conjugates resulting in visualization of lesions smaller than 1- 2 mm in diameter within 3 h."1.38Imaging small human prostate cancer xenografts after pretargeting with bispecific bombesin-antibody complexes and targeting with high specific radioactivity labeled polymer-drug conjugates. ( Ferris, C; Gada, K; Khaw, BA; Majewski, S; Panwar, R; Patil, V; Tekabe, Y; Varvarigou, A; Weisenberger, A, 2012)
"MDA-MB-468 and MDA-MB-231/H2N (231-H2N) breast cancer cells were incubated with (111)In-DTPA-anti-γH2AX-Tat (3MBq, 6MBq/μg) or a control radioimmunoconjugate, (111)In-DTPA-mIgG-Tat, and exposed to IR or bleomycin."1.38Amplification of DNA damage by a γH2AX-targeted radiopharmaceutical. ( Allen, D; Barbeau, J; Cornelissen, B; Darbar, S; Falzone, N; Kersemans, V; Smart, S; Vallis, KA, 2012)
"Tumors were clearly visualized 1 day after injecting 3."1.36PET imaging of HER1-expressing xenografts in mice with 86Y-CHX-A''-DTPA-cetuximab. ( Baidoo, KE; Brechbiel, MW; Garmestani, K; Milenic, DE; Nayak, TK; Regino, CA; Szajek, LP; Wong, KJ, 2010)
"In mice bearing LS-174T, PC-3, or A431 tumors, the tumor uptake at 3 d was 34."1.36Preparation, biological evaluation, and pharmacokinetics of the human anti-HER1 monoclonal antibody panitumumab labeled with 86Y for quantitative PET of carcinoma. ( Baidoo, KE; Brechbiel, MW; Garmestani, K; Milenic, DE; Nayak, TK, 2010)
"The MR features of pineal cysts, the difficulty of distinguishing benign cysts from cystic neoplasms, and the implications for surgical management are discussed."1.29A choroid plexus papilloma arising from an incidental pineal cyst. ( McClarty, BM; McGinn, GJ; Steven, DA, 1996)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's2 (14.29)29.6817
2010's11 (78.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhattacharyya, S1
Kurdziel, K1
Wei, L1
Riffle, L1
Kaur, G1
Hill, GC1
Jacobs, PM1
Tatum, JL1
Doroshow, JH1
Kalen, JD1
Vilhelmsson-Timmermand, O1
Santos, E1
Thorek, DL1
Evans-Axelsson, S1
Bjartell, A1
Lilja, H1
Larson, SM1
Strand, SE1
Tran, TA1
Ulmert, D1
Burvenich, IJ1
Parakh, S1
Gan, HK2
Lee, FT2
Guo, N1
Rigopoulos, A2
Lee, ST1
Gong, S1
O'Keefe, GJ2
Tochon-Danguy, H1
Kotsuma, M1
Hasegawa, J1
Senaldi, G1
Scott, AM2
Price, EW1
Edwards, KJ1
Carnazza, KE1
Carlin, SD1
Zeglis, BM1
Adam, MJ1
Orvig, C1
Lewis, JS1
Bergstrom, D1
Leyton, JV1
Zereshkian, A1
Chan, C1
Cai, Z1
Reilly, RM2
Cornelissen, B2
Kersemans, V2
McLarty, K1
Tran, L1
Vallis, KA2
Nayak, TK2
Regino, CA1
Wong, KJ1
Milenic, DE2
Garmestani, K2
Baidoo, KE2
Szajek, LP1
Brechbiel, MW2
Mountain, AJ1
Jones, GR1
Saunder, TH1
Sagona, J1
Smyth, FE1
Johns, TG1
Govindan, SV1
Goldenberg, DM1
Old, LJ1
Sankavaram, K1
Freake, HC1
Patil, V1
Gada, K1
Panwar, R1
Varvarigou, A1
Majewski, S1
Weisenberger, A1
Ferris, C1
Tekabe, Y1
Khaw, BA1
Darbar, S1
Allen, D1
Falzone, N1
Barbeau, J1
Smart, S1
Steven, DA1
McGinn, GJ1
McClarty, BM1
Chen, XG1
Li, Y1
Yan, CH1
Li, LN1
Han, R1

Other Studies

14 other studies available for pentetic acid and Cell Transformation, Neoplastic

ArticleYear
Zirconium-89 labeled panitumumab: a potential immuno-PET probe for HER1-expressing carcinomas.
    Nuclear medicine and biology, 2013, Volume: 40, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Breast Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic

2013
Radiolabeled antibodies in prostate cancer: a case study showing the effect of host immunity on antibody bio-distribution.
    Nuclear medicine and biology, 2015, Volume: 42, Issue:4

    Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Humans; Immunocompetence; Immunoconjugat

2015
Molecular Imaging and Quantitation of EphA2 Expression in Xenograft Models with 89Zr-DS-8895a.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016, Volume: 57, Issue:6

    Topics: Animals; Antibodies, Monoclonal, Humanized; Cell Line, Tumor; Cell Transformation, Neoplastic; Defer

2016
A comparative evaluation of the chelators H4octapa and CHX-A″-DTPA with the therapeutic radiometal (90)Y.
    Nuclear medicine and biology, 2016, Volume: 43, Issue:9

    Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Chelating Agents; Ethylamines; Female; I

2016
Paradoxical effects of Auger electron-emitting (111)In-DTPA-NLS-CSL360 radioimmunoconjugates on hCD45(+) cells in the bone marrow and spleen of leukemia-engrafted NOD/SCID or NRG mice.
    Nuclear medicine and biology, 2016, Volume: 43, Issue:10

    Topics: Amino Acid Sequence; Animals; Bone Marrow; Cell Line, Tumor; Cell Transformation, Neoplastic; Electr

2016
In vivo monitoring of intranuclear p27(kip1) protein expression in breast cancer cells during trastuzumab (Herceptin) therapy.
    Nuclear medicine and biology, 2009, Volume: 36, Issue:7

    Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Breast Neop

2009
PET imaging of HER1-expressing xenografts in mice with 86Y-CHX-A''-DTPA-cetuximab.
    European journal of nuclear medicine and molecular imaging, 2010, Volume: 37, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cell Line, Tumor; Cell Transform

2010
Preparation, biological evaluation, and pharmacokinetics of the human anti-HER1 monoclonal antibody panitumumab labeled with 86Y for quantitative PET of carcinoma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Volume: 51, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Area Under Curve; Biological Transport; Cell Line, Tumor; Cell Tran

2010
Immuno-PET quantitation of de2-7 epidermal growth factor receptor expression in glioma using 124I-IMP-R4-labeled antibody ch806.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Volume: 51, Issue:6

    Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Cell Line, Tumor; Cell Transformation, Neoplas

2010
The effects of transformation and ZnT-1 silencing on zinc homeostasis in cultured cells.
    The Journal of nutritional biochemistry, 2012, Volume: 23, Issue:6

    Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cation Transport Proteins; Cell Division;

2012
Imaging small human prostate cancer xenografts after pretargeting with bispecific bombesin-antibody complexes and targeting with high specific radioactivity labeled polymer-drug conjugates.
    European journal of nuclear medicine and molecular imaging, 2012, Volume: 39, Issue:5

    Topics: Animals; Antibodies, Bispecific; Antibodies, Monoclonal; Antineoplastic Agents; Bombesin; Cell Line,

2012
Amplification of DNA damage by a γH2AX-targeted radiopharmaceutical.
    Nuclear medicine and biology, 2012, Volume: 39, Issue:8

    Topics: Animals; Bleomycin; Breast Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA Breaks,

2012
A choroid plexus papilloma arising from an incidental pineal cyst.
    AJNR. American journal of neuroradiology, 1996, Volume: 17, Issue:5

    Topics: Adult; Brain Diseases; Cell Transformation, Neoplastic; Choroid Plexus Neoplasms; Contrast Media; Cy

1996
Cancer chemopreventive activities of S-3-1, a synthetic derivative of danshinone.
    Journal of Asian natural products research, 2001, Volume: 3, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Benzofurans; Bep

2001