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pentetic acid and Carcinoma, Medullary

pentetic acid has been researched along with Carcinoma, Medullary in 21 studies

Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.

Carcinoma, Medullary: A carcinoma composed mainly of epithelial elements with little or no stroma. Medullary carcinomas of the breast constitute 5%-7% of all mammary carcinomas; medullary carcinomas of the thyroid comprise 3%-10% of all thyroid malignancies. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1141; Segen, Dictionary of Modern Medicine, 1992)

Research Excerpts

ExcerptRelevanceReference
" Analysis of dose-response curves at days 20 and 40 showed additivity between RIT and paclitaxel, and analysis at day 60 suggested a synergistic effect."1.31Enhanced antitumor activity of combined pretargeted radioimmunotherapy and paclitaxel in medullary thyroid cancer xenograft. ( Barbet, J; Campion, L; Chatal, JF; Chérel, M; Faivre-Chauvet, A; Kraeber-Bodéré, F; Mirallié, E; Saï-Maurel, C; Supiot, S; Thédrez, P, 2002)
"Patients had a history of thyroid cancer or of carcinoid tumor."1.30Thoracic and abdominal SPECT-CT image fusion without external markers in endocrine carcinomas. The Group of Thyroid Tumoral Pathology of Champagne-Ardenne. ( Delisle, MJ; Liehn, JC; Pérault, C; Schvartz, C; Wampach, H, 1997)
"Patient 1 had a metastatic follicular thyroid carcinoma, patient 2 a metastatic medullary thyroid carcinoma, patient 3 tuberculosis and patient 4 an insulinoma."1.30Somatostatin receptor scintigraphy using [111In-DTPA0]RC-160 in humans: a comparison with [111In-DTPA0]octreotide. ( Breeman, WA; Krenning, EP; Kwekkeboom, DJ; van Hagen, PM; Visser, TJ, 1998)
"In patients with carcinoids, a combination of somatostatin receptor scintigraphy, chest radiograph and ultrasound of the upper abdomen had a high sensitivity for tumor localization, and detected lesions in patients in whom no tumor was found with conventional imaging, justifying the greater cost."1.29Cost-effectiveness analysis of somatostatin receptor scintigraphy. ( Habbema, JD; Krenning, EP; Kwekkeboom, DJ; Lamberts, SW, 1996)
"In midgut carcinoid (MC) patients (all scintigraphy positive), 4/29 macroscopically identified tumours gave false R(in situ)."1.29Radioisotope-guided surgery in patients with neuroendocrine tumours. ( Ahlman, H, 1996)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's15 (71.43)18.2507
2000's6 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kraeber-Bodéré, F3
Saï-Maurel, C3
Campion, L3
Faivre-Chauvet, A2
Mirallié, E1
Chérel, M1
Supiot, S1
Barbet, J4
Chatal, JF4
Thédrez, P3
Béhé, M1
Becker, W1
Gotthardt, M1
Angerstein, C1
Behr, TM1
Gao, Z1
Biersack, HJ2
Ezziddin, S1
Logvinski, T1
An, R2
Gao, ZR1
Zhang, YX1
Berná, L1
Cabezas, R1
Mora, J1
Torres, G1
Estorch, M1
Carrió, I1
Eising, EG1
Farahati, J1
Bier, D1
Knust, EJ1
Reiners, C1
Dörr, U1
Sautter-Bihl, ML1
Bihl, H1
Kwekkeboom, DJ3
Lamberts, SW1
Habbema, JD1
Krenning, EP3
Baudin, E1
Lumbroso, J1
Schlumberger, M1
Leclere, J1
Giammarile, F1
Gardet, P1
Roche, A1
Travagli, JP1
Parmentier, C1
Ahlman, H1
Kurtaran, A2
Leimer, M1
Kaserer, K2
Yang, Q1
Angelberger, P2
Niederle, B2
Virgolini, I2
Horn, JD1
Gordon, BM1
Gordon, L1
Spicer, KM1
Pérault, C1
Schvartz, C1
Wampach, H1
Liehn, JC1
Delisle, MJ1
Breeman, WA1
van Hagen, PM1
Visser, TJ1
Shi, W1
Johnston, CF1
Buchanan, KD1
Ferguson, WR1
Laird, JD1
Crothers, JG1
McIlrath, EM1
Peltier, P1
Bardet, S1
Vuillez, JP1
Bachelot, I1
Denet, S1
Olivier, P1
Leccia, F1
Corcuff, B1
Huglo, D1
Proye, C1
Rouvier, E1
Meyer, P1
Scheuba, C1
Schima, W1
Czerny, C1
Faibre-Chauvet, A1
Gautherot, E2
Fiche, M2
Le Boterff, J2
Bakker, WH1
Kooij, PP1
Erion, J1
Srinivasan, A1
de Jong, M1
Reubi, JC1
Cuccurullo, V1
Cascini, GL1
Rambaldi, PF1
Mansi, L1

Reviews

1 review available for pentetic acid and Carcinoma, Medullary

ArticleYear
[Role of somatostatin analogs in the treatment of neuroendocrine tumours].
    Minerva endocrinologica, 2001, Volume: 26, Issue:3

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Antineoplastic Agents, Hormonal; Carcinoma, Medullary; Carci

2001

Trials

5 trials available for pentetic acid and Carcinoma, Medullary

ArticleYear
Improved kinetic stability of DTPA- dGlu as compared with conventional monofunctional DTPA in chelating indium and yttrium: preclinical and initial clinical evaluation of radiometal labelled minigastrin derivatives.
    European journal of nuclear medicine and molecular imaging, 2003, Volume: 30, Issue:8

    Topics: Animals; Carcinoma, Medullary; Cell Line, Tumor; Chelating Agents; Drug Evaluation, Preclinical; Dru

2003
The role of combined imaging in metastatic medullary thyroid carcinoma: 111In-DTPA-octreotide and 131I/123I-MIBG as predictors for radionuclide therapy.
    Journal of cancer research and clinical oncology, 2004, Volume: 130, Issue:11

    Topics: 3-Iodobenzylguanidine; Adult; Carcinoma, Medullary; Female; Humans; Indium Radioisotopes; Iodine Rad

2004
[Targeted radionuclide therapy for patients with metastatic medullary thyroid carcinoma].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2006, Volume: 28, Issue:8

    Topics: 3-Iodobenzylguanidine; Adult; Aged; Antineoplastic Agents; Carcinoma, Medullary; Female; Follow-Up S

2006
Combined use of 111In-DTPA-D-Phe-1-octreotide (OCT) and 123I-vasoactive intestinal peptide (VIP) in the localization diagnosis of medullary thyroid carcinoma (MTC).
    Nuclear medicine and biology, 1996, Volume: 23, Issue:4

    Topics: Adult; Aged; Carcinoma, Medullary; Female; Humans; Indium Radioisotopes; Iodine Radioisotopes; Male;

1996
Radioimmunodetection of medullary thyroid carcinoma using indium-111 bivalent hapten and anti-CEA x anti-DTPA-indium bispecific antibody.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998, Volume: 39, Issue:7

    Topics: Adult; Aged; Antibodies, Bispecific; Biomarkers, Tumor; Carcinoembryonic Antigen; Carcinoma, Medulla

1998

Other Studies

15 other studies available for pentetic acid and Carcinoma, Medullary

ArticleYear
Enhanced antitumor activity of combined pretargeted radioimmunotherapy and paclitaxel in medullary thyroid cancer xenograft.
    Molecular cancer therapeutics, 2002, Volume: 1, Issue:4

    Topics: Animals; Antibodies, Bispecific; Carcinoembryonic Antigen; Carcinoma, Medullary; Combined Modality T

2002
111In-octreotide and 99mTc(V)-dimercaptosuccinic acid studies in the imaging of recurrent medullary thyroid carcinoma.
    The Journal of endocrinology, 1995, Volume: 144, Issue:2

    Topics: Adult; Biomarkers, Tumor; Calcitonin; Carcinoma, Medullary; Female; Humans; Male; Middle Aged; Neopl

1995
[Somatostatin receptor scintigraphy in medullary thyroid carcinomas, GEP and carcinoid tumors].
    Nuklearmedizin. Nuclear medicine, 1995, Volume: 34, Issue:1

    Topics: Adult; Aged; Calcitonin; Carcinoembryonic Antigen; Carcinoid Tumor; Carcinoma, Medullary; False Posi

1995
The contribution of somatostatin receptor scintigraphy to the diagnosis of recurrent medullary carcinoma of the thyroid.
    Seminars in oncology, 1994, Volume: 21, Issue:5 Suppl 13

    Topics: Adolescent; Adult; Aged; Calcitonin; Carcinoma, Medullary; Female; Gene Expression Regulation, Neopl

1994
Cost-effectiveness analysis of somatostatin receptor scintigraphy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:6

    Topics: Carcinoid Tumor; Carcinoma, Medullary; Carcinoma, Small Cell; Cost-Benefit Analysis; Costs and Cost

1996
Comparison of octreotide scintigraphy and conventional imaging in medullary thyroid carcinoma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:6

    Topics: Adult; Aged; Carcinoma, Medullary; Female; Humans; Indium Radioisotopes; Liver Neoplasms; Male; Midd

1996
Radioisotope-guided surgery in patients with neuroendocrine tumours.
    Digestion, 1996, Volume: 57 Suppl 1

    Topics: Carcinoid Tumor; Carcinoma, Medullary; Humans; Indium Radioisotopes; Neuroendocrine Tumors; Octreoti

1996
Octreotide uptake in the head and neck.
    Seminars in nuclear medicine, 1997, Volume: 27, Issue:1

    Topics: Carcinoma, Medullary; Diagnosis, Differential; Female; Head and Neck Neoplasms; Humans; Indium Radio

1997
Thoracic and abdominal SPECT-CT image fusion without external markers in endocrine carcinomas. The Group of Thyroid Tumoral Pathology of Champagne-Ardenne.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:8

    Topics: 3-Iodobenzylguanidine; Abdominal Neoplasms; Carcinoid Tumor; Carcinoma, Medullary; Feasibility Studi

1997
Somatostatin receptor scintigraphy using [111In-DTPA0]RC-160 in humans: a comparison with [111In-DTPA0]octreotide.
    European journal of nuclear medicine, 1998, Volume: 25, Issue:2

    Topics: Adenocarcinoma, Follicular; Adult; Carcinoma, Medullary; Female; Humans; Indium Radioisotopes; Insul

1998
Localization of neuroendocrine tumours with [111In] DTPA-octreotide scintigraphy (Octreoscan): a comparative study with CT and MR imaging.
    QJM : monthly journal of the Association of Physicians, 1998, Volume: 91, Issue:4

    Topics: Adolescent; Adult; Aged; Carcinoid Tumor; Carcinoma, Medullary; Child; Female; Humans; Indium Radioi

1998
Indium-111-DTPA-D-Phe-1-octreotide and technetium-99m-(V)-dimercaptosuccinic acid scanning in the preoperative staging of medullary thyroid carcinoma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998, Volume: 39, Issue:11

    Topics: Carcinoma, Medullary; Female; Humans; Indium Radioisotopes; Lymph Nodes; Lymphatic Metastasis; Male;

1998
Bispecific antibody and bivalent hapten radioimmunotherapy in CEA-producing medullary thyroid cancer xenograft.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1999, Volume: 40, Issue:1

    Topics: Animals; Antibodies, Bispecific; Antibodies, Monoclonal; Carcinoembryonic Antigen; Carcinoma, Medull

1999
Toxicity and efficacy of radioimmunotherapy in carcinoembryonic antigen-producing medullary thyroid cancer xenograft: comparison of iodine 131-labeled F(ab')2 and pretargeted bivalent hapten and evaluation of repeated injections.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:10 Suppl

    Topics: Animals; Carcinoembryonic Antigen; Carcinoma, Medullary; Haptens; Humans; Immunoglobulin Fab Fragmen

1999
Cholecystokinin receptor imaging using an octapeptide DTPA-CCK analogue in patients with medullary thyroid carcinoma.
    European journal of nuclear medicine, 2000, Volume: 27, Issue:9

    Topics: Carcinoma, Medullary; Humans; Indium Radioisotopes; Pentetic Acid; Radionuclide Imaging; Receptor, C

2000