pentetic acid has been researched along with Cancer of Ovary in 46 studies
Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.
Excerpt | Relevance | Reference |
---|---|---|
"Epithelial ovarian cancer (EOC) is usually diagnosed at an advanced stage and has poor prognosis." | 1.72 | Develop companion radiopharmaceutical YKL40 antibodies as potential theranostic agents for epithelial ovarian cancer. ( Chang, MC; Chen, CA; Chen, IC; Chiang, PF; Chiang, YC; Huang, CY; Kuo, YJ; Peng, CL, 2022) |
"Ovarian cancer is the most lethal gynecologic malignancy, often diagnosed at advanced stage leading to poor prognosis." | 1.35 | Harnessing competing endocytic pathways for overcoming the tumor-blood barrier: magnetic resonance imaging and near-infrared imaging of bifunctional contrast media. ( Kalchenko, V; Kohen, F; Meir, G; Migalovich, HS; Neeman, M; Nevo, N, 2009) |
"DFO and DTPA were cytotoxic to ovarian cancer cells in a dose- and time-dependent manner." | 1.33 | Iron chelators deferoxamine and diethylenetriamine pentaacetic acid induce apoptosis in ovarian carcinoma. ( Brard, L; Granai, CO; Swamy, N, 2006) |
"Colon cancer is the second most common cause of cancer mortality." | 1.30 | Indium-111 satumomab pendetide: the first FDA-approved monoclonal antibody for tumor imaging. ( Bohdiewicz, PJ, 1998) |
" The purpose of this study was to determine a dosing schema of an adenoviral vector encoding the human somatostatin receptor subtype 2 (AdCMVhSSTr2) for achieving the highest tumor localization of [(111)In]-DTPA-D-Phe1-octreotide, which binds to this receptor, in a human ovarian cancer model as a prelude to future therapy studies." | 1.30 | In vivo localization of [(111)In]-DTPA-D-Phe1-octreotide to human ovarian tumor xenografts induced to express the somatostatin receptor subtype 2 using an adenoviral vector. ( Bright, SJ; Buchsbaum, DJ; Curiel, DT; Della Manna, D; Kirkman, RL; Mayo, MS; McLean, SF; Myracle, AD; Olsen, CC; Rogers, BE, 1999) |
" The pharmacokinetic study showed a retention half-life of 25." | 1.29 | Pharmacokinetics and biodistribution of samarium-153-labelled OC125 antibody coupled to CITCDTPA in a xenograft model of ovarian cancer. ( Bardiès, M; Chatal, JF; Faivre-Chauvet, A; Imai, S; Kraeber-Bodéré, F; Le Boterff, J; Mishra, A; Thédrez, P, 1996) |
"VX2 carcinoma (squamous cell carcinoma) was implanted in either the brain, lung, ovary, bone or muscle of rabbits." | 1.29 | Contrast-enhanced MRI with gadodiamide injection in rabbit carcinoma models. ( Furuhama, K; Hirose, T; Ikehira, H; Jinbo, T; Kato, H; Miyahara, K; Sato, M; Sugihara, H; Tateno, Y; Yamada, K, 1996) |
" Changes in relaxation times in normal and abnormal tissues following contrast medium, toxicity and dosage of gadolinium-DTPA, and MRI pulse sequence techniques are reviewed." | 1.27 | Contrast-enhanced magnetic resonance imaging of tumours of the central nervous system: a clinical review. ( Graif, M; Steiner, RE, 1986) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (6.52) | 18.7374 |
1990's | 30 (65.22) | 18.2507 |
2000's | 7 (15.22) | 29.6817 |
2010's | 5 (10.87) | 24.3611 |
2020's | 1 (2.17) | 2.80 |
Authors | Studies |
---|---|
Chang, MC | 1 |
Chiang, PF | 1 |
Kuo, YJ | 1 |
Peng, CL | 1 |
Chen, IC | 1 |
Huang, CY | 1 |
Chen, CA | 1 |
Chiang, YC | 1 |
Feldmann, DP | 1 |
Jones, S | 1 |
Douglas, K | 1 |
Shields, AF | 1 |
Merkel, OM | 1 |
Liu, P | 3 |
Boyle, AJ | 3 |
Lu, Y | 3 |
Adams, J | 1 |
Chi, Y | 1 |
Reilly, RM | 3 |
Winnik, MA | 3 |
Migalovich, HS | 1 |
Kalchenko, V | 1 |
Nevo, N | 1 |
Meir, G | 1 |
Kohen, F | 1 |
Neeman, M | 1 |
Nayak, TK | 1 |
Garmestani, K | 1 |
Baidoo, KE | 1 |
Milenic, DE | 1 |
Brechbiel, MW | 2 |
Weinrich, D | 1 |
Scollard, DA | 1 |
Ngo Njock Mbong, G | 1 |
Siegel, BA | 1 |
Dehdashti, F | 1 |
Mutch, DG | 1 |
Podoloff, DA | 2 |
Wendt, R | 1 |
Sutton, GP | 1 |
Burt, RW | 1 |
Ellis, PR | 1 |
Mathias, CJ | 1 |
Green, MA | 1 |
Gershenson, DM | 1 |
Adams, GP | 1 |
Shaller, CC | 1 |
Dadachova, E | 1 |
Simmons, HH | 1 |
Horak, EM | 1 |
Tesfaye, A | 1 |
Klein-Szanto, AJ | 1 |
Marks, JD | 1 |
Weiner, LM | 1 |
Brard, L | 1 |
Granai, CO | 1 |
Swamy, N | 1 |
Orlova, A | 2 |
Rosik, D | 1 |
Sandström, M | 1 |
Lundqvist, H | 1 |
Einarsson, L | 1 |
Tolmachev, V | 2 |
Tran, T | 1 |
Widström, C | 1 |
Engfeldt, T | 1 |
Eriksson Karlström, A | 1 |
Müller, C | 1 |
Schibli, R | 1 |
Krenning, EP | 1 |
de Jong, M | 1 |
Low, RN | 1 |
Carter, WD | 1 |
Saleh, F | 1 |
Sigeti, JS | 1 |
Kosmas, C | 1 |
Maraveyas, A | 1 |
Gooden, CS | 1 |
Snook, D | 1 |
Epenetos, AA | 1 |
Bohdiewicz, PJ | 2 |
Scott, GC | 1 |
Juni, JE | 1 |
Fink-Bennett, D | 1 |
Wilner, F | 1 |
Nagle, C | 1 |
Dworkin, HJ | 1 |
Yamashita, Y | 2 |
Torashima, M | 2 |
Hatanaka, Y | 2 |
Harada, M | 1 |
Higashida, Y | 1 |
Takahashi, M | 2 |
Mizutani, H | 1 |
Tashiro, H | 1 |
Iwamasa, J | 1 |
Miyazaki, K | 2 |
Hempling, RE | 1 |
Piver, MS | 1 |
Baker, TR | 1 |
Bakshi, S | 1 |
Gilani, SS | 1 |
Cannistra, SA | 1 |
Neal, CE | 2 |
Baker, MR | 1 |
Hilgers, RD | 1 |
Fanning, J | 1 |
Burke, RC | 1 |
Snodgrass, J | 1 |
Cull, RD | 1 |
Kim, EE | 2 |
Kasi, LP | 1 |
Surwit, EA | 2 |
Childers, JM | 1 |
Krag, DN | 1 |
Katterhagen, JG | 1 |
Gallion, HH | 1 |
Waggoner, S | 1 |
Mann, WJ | 1 |
Tibben, JG | 1 |
Thomas, CM | 1 |
Massuger, LF | 1 |
Segers, MF | 1 |
Schijf, CP | 1 |
Corstens, FH | 1 |
Boerman, OC | 1 |
Reuter, M | 1 |
Steffens, JC | 1 |
Schüppler, U | 1 |
Muhle, C | 1 |
Brinkmann, G | 1 |
Kohl, A | 1 |
Weisner, D | 1 |
Lüttges, J | 1 |
Spielmann, RP | 1 |
Heller, M | 1 |
Method, MW | 1 |
Serafini, AN | 1 |
Averette, HE | 1 |
Rodriguez, M | 1 |
Penalver, MA | 1 |
Sevin, BU | 1 |
Kraeber-Bodéré, F | 1 |
Mishra, A | 1 |
Thédrez, P | 2 |
Faivre-Chauvet, A | 1 |
Bardiès, M | 1 |
Imai, S | 1 |
Le Boterff, J | 1 |
Chatal, JF | 2 |
Yamada, K | 1 |
Jinbo, T | 1 |
Miyahara, K | 1 |
Sato, M | 1 |
Hirose, T | 1 |
Kato, H | 1 |
Tateno, Y | 1 |
Ikehira, H | 1 |
Sugihara, H | 1 |
Furuhama, K | 1 |
Johnson, DL | 1 |
Cornwell, VL | 1 |
Markwell, S | 1 |
Nguyen, BD | 1 |
Regan, F | 1 |
Okamura, H | 1 |
Mardirossian, G | 1 |
Brill, AB | 1 |
Harwood, SJ | 1 |
Olsen, J | 1 |
Dwyer, KA | 1 |
Siegel, JA | 1 |
Rogers, BE | 1 |
McLean, SF | 1 |
Kirkman, RL | 1 |
Della Manna, D | 1 |
Bright, SJ | 1 |
Olsen, CC | 1 |
Myracle, AD | 1 |
Mayo, MS | 1 |
Curiel, DT | 1 |
Buchsbaum, DJ | 1 |
Inoue, T | 1 |
Li, C | 1 |
Yang, DJ | 1 |
Higuchi, T | 1 |
Oriuchi, N | 1 |
Yu, D | 1 |
Milas, L | 1 |
Hunter, N | 1 |
Wallace, S | 1 |
Pinkas, L | 1 |
Robins, PD | 1 |
Forstrom, LA | 1 |
Mahoney, DW | 1 |
Mullan, BP | 1 |
Reilly, R | 1 |
Lee, N | 1 |
Houle, S | 1 |
Law, J | 1 |
Marks, A | 1 |
Gallup, DG | 1 |
Maguire, RT | 1 |
Jusko, WJ | 1 |
Kung, LP | 1 |
Schmelter, RF | 1 |
Stevens, SK | 1 |
Hricak, H | 1 |
Stern, JL | 1 |
Hötzinger, H | 1 |
Salbeck, R | 1 |
Toedt, C | 1 |
Beyer, HK | 1 |
Hnatowich, DJ | 1 |
Chinol, M | 1 |
Siebecker, DA | 1 |
Gionet, M | 1 |
Griffin, T | 1 |
Doherty, PW | 1 |
Hunter, R | 1 |
Kase, KR | 1 |
Fumoleau, P | 1 |
Saccavini, JC | 1 |
Curtet, C | 1 |
Bianco-Arco, A | 1 |
Chetanneau, A | 1 |
Peltier, P | 1 |
Kremer, M | 1 |
Guillard, Y | 1 |
Graif, M | 1 |
Steiner, RE | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
First in Man Study Investigating the Biodistribution, the Safety and Optimal Recommended Dose of a New Radiolabelled Monoclonal Antibody Targeting Frizzled Homolog 10 (FZD10) in Patients With Relapsed or Refractory Non Resectable Synovial Sarcomas[NCT01469975] | Phase 1 | 20 participants (Actual) | Interventional | 2011-12-31 | Terminated (stopped due to Too slow accrual.) | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 review available for pentetic acid and Cancer of Ovary
Article | Year |
---|---|
Clinical experience with radiolabelled monoclonal antibodies in the detection of colorectal and ovarian carcinoma recurrence and review of the literature.
Topics: Adult; Aged; Antibodies, Monoclonal; Colorectal Neoplasms; Diagnostic Errors; Female; Humans; Indium | 1999 |
5 trials available for pentetic acid and Cancer of Ovary
Article | Year |
---|---|
Anti-chelate antibodies after intraperitoneal yttrium-90-labeled monoclonal antibody immunoconjugates for ovarian cancer therapy.
Topics: Antibodies; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin G; | 1995 |
Clinical assessment of 111In-CYT-103 immunoscintigraphy in ovarian cancer.
Topics: Adenocarcinoma; Antibodies, Monoclonal; Antigens, Neoplasm; Female; Glycoproteins; Humans; Indium Ra | 1993 |
The role of radioimmunoscintigraphy and computed tomography scan prior to reassessment laparotomy of patients with ovarian carcinoma. A preliminary report.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; | 1996 |
Multicenter clinical trial of 111In-CYT-103 in patients with ovarian cancer.
Topics: Adult; Antibodies, Monoclonal; Female; Humans; Indium Radioisotopes; Neoplasm Recurrence, Local; Neo | 1992 |
Impact of 111In-CYT-103 on the surgical management of patients with ovarian cancer.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Female; Humans; Indium Radioisotopes; Middle | 1992 |
40 other studies available for pentetic acid and Cancer of Ovary
Article | Year |
---|---|
Develop companion radiopharmaceutical YKL40 antibodies as potential theranostic agents for epithelial ovarian cancer.
Topics: Animals; Antibodies, Neutralizing; Ascites; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Chitina | 2022 |
Microfluidic Assembly of siRNA-Loaded Micelleplexes for Tumor Targeting in an Orthotopic Model of Ovarian Cancer.
Topics: Animals; Cell Line, Tumor; Female; Heterografts; Humans; Mice; Microfluidics; Nanoparticles; Ovarian | 2019 |
Metal-Chelating Polymers (MCPs) with Zwitterionic Pendant Groups Complexed to Trastuzumab Exhibit Decreased Liver Accumulation Compared to Polyanionic MCP Immunoconjugates.
Topics: Acrylic Resins; Animals; Antibodies, Monoclonal; Biotin; Cell Line, Tumor; Chelating Agents; Ethylen | 2015 |
Harnessing competing endocytic pathways for overcoming the tumor-blood barrier: magnetic resonance imaging and near-infrared imaging of bifunctional contrast media.
Topics: Animals; Antineoplastic Agents; Biological Transport; Endocytosis; Female; Humans; Isoflavones; Mice | 2009 |
PET imaging of tumor angiogenesis in mice with VEGF-A-targeted (86)Y-CHX-A″-DTPA-bevacizumab.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevaciz | 2011 |
Biotinylated polyacrylamide-based metal-chelating polymers and their influence on antigen recognition following conjugation to a trastuzumab Fab fragment.
Topics: Acrylic Resins; Antibodies, Monoclonal, Humanized; Biotin; Biotinylation; Breast Neoplasms; Cell Lin | 2012 |
The effect of metal-chelating polymers (MCPs) for 111In complexed via the streptavidin-biotin system to trastuzumab Fab fragments on tumor and normal tissue distribution in mice.
Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biotin; Cell Line, Tumor; Chelati | 2013 |
Evaluation of 111In-DTPA-folate as a receptor-targeted diagnostic agent for ovarian cancer: initial clinical results.
Topics: Adult; Aged; Carrier Proteins; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Indium Ra | 2003 |
A single treatment of yttrium-90-labeled CHX-A"-C6.5 diabody inhibits the growth of established human tumor xenografts in immunodeficient mice.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Immunoglobulin Variable Region; Immunot | 2004 |
Iron chelators deferoxamine and diethylenetriamine pentaacetic acid induce apoptosis in ovarian carcinoma.
Topics: Animals; Apoptosis; Caspases; Cell Growth Processes; Cell Line, Tumor; Deferoxamine; Enzyme Activati | 2006 |
Evaluation of [(111/114m)In]CHX-A''-DTPA-ZHER2:342, an affibody ligand coniugate for targeting of HER2-expressing malignant tumors.
Topics: Animals; Antibodies, Monoclonal; Cell Survival; Female; Ligands; Metabolic Clearance Rate; Mice; Org | 2007 |
Pre-clinical evaluation of [111In]-benzyl-DOTA-Z(HER2:342), a potential agent for imaging of HER2 expression in malignant tumors.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Drug Evaluation, Preclinical; Female; Genes, erbB-2; Hu | 2007 |
Pemetrexed improves tumor selectivity of 111In-DTPA-folate in mice with folate receptor-positive ovarian cancer.
Topics: Animals; Autoradiography; Carrier Proteins; Cell Line, Tumor; Female; Folate Receptors, GPI-Anchored | 2008 |
Ovarian cancer: comparison of findings with perfluorocarbon-enhanced MR imaging, In-111-CYT-103 immunoscintigraphy, and CT.
Topics: Abdominal Neoplasms; Antibodies, Monoclonal; Contrast Media; Drug Combinations; Female; Fluorocarbon | 1995 |
Indium-111 OncoScint CR/OV and F-18 FDG in colorectal and ovarian carcinoma recurrences. Early observations.
Topics: Aged; Antibodies, Monoclonal; Colorectal Neoplasms; Deoxyglucose; Female; Fluorine Radioisotopes; Fl | 1995 |
Adnexal masses: accuracy of characterization with transvaginal US and precontrast and postcontrast MR imaging.
Topics: Adnexal Diseases; Adolescent; Adult; Aged; Contrast Media; Fallopian Tube Neoplasms; Female; Gadolin | 1995 |
Immunoscintigraphy using 111InCyt103 prior to second look laparotomy in ovarian cancer. A pilot study.
Topics: Adult; Aged; Antibodies, Monoclonal; Antigens, Tumor-Associated, Carbohydrate; Carcinoma; Female; Hu | 1994 |
111In-CYT-103 immunoscintigraphy in ovarian cancer.
Topics: Antibodies, Monoclonal; Antigens, Tumor-Associated, Carbohydrate; Female; Humans; Indium Radioisotop | 1993 |
In-111 CYT-103 immunoscintigraphy in the imaging of ovarian carcinoma.
Topics: Antibodies, Monoclonal; Female; Humans; Indium Radioisotopes; Laparotomy; Middle Aged; Neoplasm Recu | 1993 |
Challenges in immunoscintigraphy of ovarian cancer.
Topics: Antibodies, Monoclonal; Female; Humans; Indium Radioisotopes; Oligopeptides; Ovarian Neoplasms; Pent | 1993 |
Oncoscint for detection of disseminated colorectal and ovarian cancer.
Topics: Adenocarcinoma; Antibodies, Monoclonal; Colorectal Neoplasms; Female; Humans; Indium Radioisotopes; | 1993 |
Humoral anti-OV-TL 3 response after the intravenous administration of radiolabelled Fab' or F(ab')2 fragments in ovarian cancer patients.
Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antibodies, Neoplasm; Chelating Agents; | 1995 |
[Preoperative differential diagnosis of cystic adnexal tumors: double-contrast MRT].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Contrast Media; Cystadenocarcinoma; Cystadenoma; Dia | 1996 |
Pharmacokinetics and biodistribution of samarium-153-labelled OC125 antibody coupled to CITCDTPA in a xenograft model of ovarian cancer.
Topics: Animals; Cystadenocarcinoma, Serous; Female; Humans; Isothiocyanates; Isotope Labeling; Mice; Mice, | 1996 |
Contrast-enhanced MRI with gadodiamide injection in rabbit carcinoma models.
Topics: Animals; Bone Neoplasms; Brain Neoplasms; Carcinoma, Squamous Cell; Contrast Media; Female; Gadolini | 1996 |
Quantitative analysis of In-111 satumomab pendetide immunoscintigraphy. An aid to visual interpretation of images in patients with suspected carcinomatosis.
Topics: Abdomen; Antibodies, Monoclonal; Carcinoma; Colorectal Neoplasms; Female; Femur; Humans; Ilium; Indi | 1996 |
In-111 CYT-103 immunoscintigraphy of isolated splenic metastasis from ovarian carcinoma.
Topics: Adult; Antibodies, Monoclonal; Cystadenocarcinoma, Serous; Female; Humans; Indium Radioisotopes; Oli | 1997 |
Characterization of sonographically indeterminate ovarian tumors with MR imaging. A logistic regression analysis.
Topics: Contrast Media; Diagnosis, Computer-Assisted; Female; Gadolinium; Gadolinium DTPA; Humans; Logistic | 1997 |
Radiation absorbed dose estimates for indium-111-labeled B72.3, an IgG antibody to ovarian and colorectal cancer: MIRD dose estimate report No. 18.
Topics: Antibodies, Monoclonal; Colorectal Neoplasms; Female; Humans; Indium Radioisotopes; Male; Oligopepti | 1998 |
Indium-111 satumomab pendetide: the first FDA-approved monoclonal antibody for tumor imaging.
Topics: Aged; Antibodies, Monoclonal; Clinical Trials as Topic; Colonic Neoplasms; Drug Approval; Female; Hu | 1998 |
In vivo localization of [(111)In]-DTPA-D-Phe1-octreotide to human ovarian tumor xenografts induced to express the somatostatin receptor subtype 2 using an adenoviral vector.
Topics: Adenoviridae; Animals; Antineoplastic Agents, Hormonal; Binding, Competitive; Female; Genetic Vector | 1999 |
Evaluation of In-111 DTPA-paclitaxel scintigraphy to predict response on murine tumors to paclitaxel.
Topics: Animals; Carcinoma, Squamous Cell; Drug Resistance, Neoplasm; Female; Fibrosarcoma; Liver; Mammary N | 1999 |
In vitro stability of EDTA and DTPA immunoconjugates of monoclonal antibody 2G3 labeled with indium-111.
Topics: Antibodies, Monoclonal; Ascitic Fluid; Drug Stability; Edetic Acid; Female; Humans; In Vitro Techniq | 1992 |
OncoScint image atlas.
Topics: Antibodies, Monoclonal; Atlases as Topic; Colorectal Neoplasms; Female; Humans; Indium Radioisotopes | 1992 |
Immunopharmacokinetics of 111In-CYT-103 in ovarian cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Female; Half-Life; Humans; Indium Radioisoto | 1992 |
Ovarian lesions: detection and characterization with gadolinium-enhanced MR imaging at 1.5 T.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Contrast Media; Drug Combinations; Female; Gadolinium; G | 1991 |
[Initial experience with the use of oral gadolinium-DTPA in nuclear magnetic resonance tomography of the pelvis].
Topics: Administration, Oral; Adult; Aged; Contrast Media; Female; Gadolinium DTPA; Humans; Magnetic Resonan | 1990 |
Patient biodistribution of intraperitoneally administered yttrium-90-labeled antibody.
Topics: Animals; Antibodies, Monoclonal; Female; Humans; Immunization; Injections, Intraperitoneal; Mice; Mi | 1988 |
Immunoscintigraphy of recurrences of gynecologic carcinomas.
Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Tumor-Associated, | 1987 |
Contrast-enhanced magnetic resonance imaging of tumours of the central nervous system: a clinical review.
Topics: Astrocytoma; Brain Neoplasms; Breast Neoplasms; Female; Gadolinium; Humans; Magnetic Resonance Spect | 1986 |