pentetic acid and Brain Neoplasms studies

Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research Excerpts

Excerpt	Relevance	Reference
"Findings on cranial magnetic resonance (MR) images were correlated with known histopathologic findings in 42 patients with tuberous sclerosis (TS), 17 of whom received gadopentetate dimeglumine, to extend the range of signs on MR images."	8.78	MR imaging of tuberous sclerosis: pathogenesis of this phakomatosis, use of gadopentetate dimeglumine, and literature review. ( Altman, NR; Bilaniuk, LT; Braffman, BH; Brody, BA; Naidich, TP; Post, MJ; Quencer, RM; Zimmerman, RA, 1992)
"To delineate the tumor margins of malignant gliomas laser-induced fluorescence detection technique was applied using 5-aminofluorescein-albumin as the fluorescent dye."	7.70	Laser-induced fluorescence detection of malignant gliomas using fluorescein-labeled serum albumin: experimental and preliminary clinical results. ( Albert, FK; Haase, T; Kremer, P; Kunze, S; Rheinwald, M; Sinn, H; Wunder, A; Zillmann, U, 2000)
"To characterize the gadopentetate dimeglumine-enhanced MR features of recurrent medulloblastoma."	7.69	Postoperative evaluation for intracranial recurrence of medulloblastoma: MR findings with gadopentetate dimeglumine. ( Chess, MA; Meyers, SP; Tarr, RW; Wildenhain, S, 1994)
"It was concluded that in brain metastases of mammary carcinoma Lact represents a product of ischemia preceding/during tissue decay resulting in central necrosis, rather than tumor specific metabolism resulting in increased glycolysis."	5.29	Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma. ( Oudkerk, M; Sijens, PE; van Dijk, P, 1994)
"Findings on cranial magnetic resonance (MR) images were correlated with known histopathologic findings in 42 patients with tuberous sclerosis (TS), 17 of whom received gadopentetate dimeglumine, to extend the range of signs on MR images."	4.78	MR imaging of tuberous sclerosis: pathogenesis of this phakomatosis, use of gadopentetate dimeglumine, and literature review. ( Altman, NR; Bilaniuk, LT; Braffman, BH; Brody, BA; Naidich, TP; Post, MJ; Quencer, RM; Zimmerman, RA, 1992)
"To delineate the tumor margins of malignant gliomas laser-induced fluorescence detection technique was applied using 5-aminofluorescein-albumin as the fluorescent dye."	3.70	Laser-induced fluorescence detection of malignant gliomas using fluorescein-labeled serum albumin: experimental and preliminary clinical results. ( Albert, FK; Haase, T; Kremer, P; Kunze, S; Rheinwald, M; Sinn, H; Wunder, A; Zillmann, U, 2000)
"MR images were studied prospectively in each of 31 patients with brain tumors (11 gliomas, 6 meningiomas, 6 neurinomas, and 8 others) before and after intravenous injection of gadopentetate dimeglumine."	3.69	Contrast enhancement of brain tumors at different MR field strengths: comparison of 0.5 T and 2.0 T. ( Cha, SH; Chang, KH; Han, MC; Han, MH; Kim, HD; Ra, DG, 1994)
"To characterize the gadopentetate dimeglumine-enhanced MR features of recurrent medulloblastoma."	3.69	Postoperative evaluation for intracranial recurrence of medulloblastoma: MR findings with gadopentetate dimeglumine. ( Chess, MA; Meyers, SP; Tarr, RW; Wildenhain, S, 1994)
"In meningiomas, a flat, contrast-enhancing, probably dural structure adjacent to the tumor can occasionally be observed on Gadolinium-DTPA enhanced MR images."	3.68	"Meningeal sign": a characteristic finding of meningiomas on contrast-enhanced MR images. ( Felix, R; Henkes, H; Lanksch, W; Schörner, W; Schubeus, P, 1990)
"Experience in three patients (one each with meningioma, pineal tumor, and prominent jugular bulb) illustrates that magnetic resonance (MR) angiography can benefit from the administration of gadolinium diethylenetriaminepentaacetic acid."	3.68	Gadolinium-enhanced MR angiography. ( Creasy, JL; Goins, D; Kessler, RM; Partain, CL; Presbrey, T; Price, RR, 1990)
"Using RG-C6 glioma-transplanted rats, we studied precontrast and postcontrast magnetic resonance imaging, extravasation of Evans blue, and histology."	3.68	Magnetic resonance imaging of experimental rat brain tumors: histopathological evaluation. ( Baba, T; Fukui, M; Inoue, T; Katsuki, C; Moriguchi, M; Natori, Y, 1990)
"The enhancement properties of gadolinium diethylenetriaminepentaacetic acid (DTPA) and gadolinium tetraazacyclododecanetetraacetic acid (DOTA) were compared using a rat glioma model."	3.67	MR imaging of rat brain glioma: Gd-DTPA versus Gd-DOTA. ( Adelman, LS; Jacobson, S; Kaufman, D; Runge, VM; Wood, ML, 1988)
" The article shows in what manner the image is influenced by the dosage of the contrast medium and also by the time interval elapsing between injection of the contrast medium and production of the NMR tomogram."	2.65	[Human testing of the nuclear spin tomographic contrast medium gadolinium-DTPA. Tolerance, contrast affect and the 1st clinical results]. ( Claussen, C; Felix, R; Fiegler, W; Kazner, E; Lange, L; Laniado, M; Schörner, W; Speck, U; Weinmann, HJ, 1984)
"Slightly less than half of pediatric brain tumors are in the posterior fossa."	2.38	Magnetic resonance imaging of pediatric brain tumors. ( Fitz, C, 1993)
"Brain tumors were induced in Balb/c mice via intracranial injection of Lewis Lung carcinoma cells into the right hemisphere of the mouse brain using stereotaxic apparatus."	1.39	Examination of blood-brain barrier (BBB) integrity in a mouse brain tumor model. ( Bachmeier, CJ; Hatch, GM; Miller, DW; Mitchell, R; On, NH; Savant, SD, 2013)
"Brain edema in gliomas is an epiphenomenon related to blood-brain-barrier (BBB) breakdown in which endothelial nitric oxide synthase (eNOS) plays a key role."	1.36	The role of eNOS in vascular permeability in ENU-induced gliomas. ( Argandoña, EG; Bengoetxea, H; Bulnes, S; Lafuente, JV; Leis, O; Ortuzar, N, 2010)
"Pediatric brain tumors, especially medulloblastomas, express somatostatin receptors."	1.34	[Imaging of pediatric brain tumors using somatostatin analogue 111Ih-DTPA-D-Phe1-octreotide]. ( Balázs, G; Bognár, L; Constantin, T; Dabasi, G; Garami, M; Hauser, P; Karádi, Z; Kertész, GP; Klekner, A; Schuler, D, 2007)
"MR imaging contrast of brain metastases after cumulative doses of gadolinium chelate is quantitated and compared in order to assess the clinical utility of high dosage."	1.30	Gd-enhanced MR imaging of brain metastases: contrast as a function of dose and lesion size. ( Oudkerk, M; Schmitz, PI; Sijens, PE; Van Dijk, P, 1997)
"Present day imaging of brain tumors requires a disrupted blood-brain barrier (BBB)."	1.30	Imaging brain tumors by targeting peptide radiopharmaceuticals through the blood-brain barrier. ( Kurihara, A; Pardridge, WM, 1999)
"The histological diagnosis was microcystic meningioma."	1.30	Microcystic meningioma without enhancement on neuroimaging--case report. ( Hara, A; Kagawa, Y; Kubota, Y; Sakai, N; Ueda, T, 1997)
" We found 2D-TOF alone, or at times in combination with SAS, useful for planning of operation for convexity lesions."	1.30	Usefulness of two-dimensional time-of-flight MR angiography combined with surface anatomy scanning for convexity lesions. ( Arita, K; Ikawa, F; Kurisu, K; Kutsuna, M; Migita, K; Pant, B; Sumida, M; Uozumi, T, 1997)
"Eight patients with intra-axial brain tumors (three glioblastoma multiforme, one low-grade astrocytoma, one lymphoma, one medulloblastoma, one neurocytoma and one metastatic tumor) were studied."	1.29	Indium-111-pentetreotide imaging in intra-axial brain tumors: comparison with thallium-201 SPECT and MRI. ( Chang, JW; Kim, DI; Lee, JD; Lee, JT; Park, CY, 1995)
"It was concluded that in brain metastases of mammary carcinoma Lact represents a product of ischemia preceding/during tissue decay resulting in central necrosis, rather than tumor specific metabolism resulting in increased glycolysis."	1.29	Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma. ( Oudkerk, M; Sijens, PE; van Dijk, P, 1994)
"The different cerebral tumors (glioma, schwannoma, neuroblastoma) showed no difference in relaxation times, but all tumors had T1(1301 +/- 167 ms) and T2(91 +/- 9 ms) times distinctly longer than normal brain (T1: 1057 +/- 77 ms; T2: 77 +/- 6 ms)."	1.29	Quantitative magnetic resonance imaging of rat brain tumors: in vivo NMR relaxometry for the discrimination of normal and pathological tissues. ( Bockhorst, K; Hoehn-Berlage, M, 1994)
"We encountered a case of brain abscess that was difficult to differentiate from glioblastoma."	1.29	Brain abscess observed by localized proton magnetic resonance spectroscopy. ( Harada, M; Kannuki, S; Miyoshi, H; Nishitani, H; Tanouchi, M, 1994)
"Cubic volumes containing brain metastases of lung cancer (n = 17), mammary carcinoma (n = 24), melanoma (n = 12) and those originating from other tumors (n = 13) were examined using the double spin echo technique with CHESS pulses for water suppression and TE = 135 ms."	1.29	1H MR spectroscopy detection of lipids and lactate in metastatic brain tumors. ( Levendag, PC; Oudkerk, M; Sijens, PE; van Dijk, P; Vecht, CJ, 1996)
"Pituitary tumors were slightly positive in 50% of cases only, independent of the endocrine activity."	1.29	Somatostatin receptor scintigraphy in brain tumors and pituitary tumors: first experiences. ( Hildebrandt, G; Klug, N; Luyken, C; Scheidhauer, K; Schicha, H; Schomäcker, K, 1993)
"Brainstem gliomas are an important oncologic problem in the pediatric age group, constituting between 10 and 15% of childhood central nervous system neoplasms."	1.29	Prognostic value of contrast-enhanced magnetic resonance imaging in brainstem gliomas. ( Friedman, HS; Kerby, T; Moghrabi, A; Tien, RD, 1995)
"VX2 carcinoma (squamous cell carcinoma) was implanted in either the brain, lung, ovary, bone or muscle of rabbits."	1.29	Contrast-enhanced MRI with gadodiamide injection in rabbit carcinoma models. ( Furuhama, K; Hirose, T; Ikehira, H; Jinbo, T; Kato, H; Miyahara, K; Sato, M; Sugihara, H; Tateno, Y; Yamada, K, 1996)
"We studied 28 patients with brain tumors by MRI."	1.29	[Magnetic resonance tomographic characterization of intracranial tumors by evaluating the blood-brain barrier and regional cerebral circulation]. ( Böck, JC; Felix, R; Sander, B; Schedel, H, 1993)
"A patient had severe hydrocephalus and diffuse leptomeningeal enhancement on MR which mimicked leptomeningeal spread of a primary brain tumor."	1.29	Gadolinium enhancement of the leptomeninges caused by hydrocephalus: a potential mimic of leptomeningeal metastasis. ( Friedman, H; Schumacher, DJ; Tien, RD, 1994)
"In our series, 3 cases with primary brain tumors developed spinal subarachnoid involvement."	1.29	MRI manifestations of leptomeningeal metastasis. ( Chou, MS; Howng, SL; Lin, MB; Liu, GC; Tsai, TC, 1994)
"8 mmHg, maximum absorption rate into capillaries was estimated to be 0."	1.29	Formation and resolution of brain edema associated with brain tumors. A comprehensive theoretical model and clinical analysis. ( Nagashima, T; Tada, Y; Takada, M; Tamaki, N, 1994)
"Gadolinium-DTPA has been shown to be a good probe for demonstrating defects in the blood-brain barrier, but it has a rapid rate of elimination so that peak circulating levels are short-lived."	1.28	Dynamic imaging of contrast enhancement in brain tumors. ( Bullock, PR; Firth, JL; Gowland, P; Mansfield, P; Worthington, BS, 1991)
"A specific group of intrinsic dorsal midbrain tumors was identified in six children by computerized tomography (CT) and magnetic resonance (MR) imaging."	1.28	Benign intrinsic tectal "tumors" in children. ( Blaser, SI; Harwood-Nash, DC; Hoffman, HJ; Humphreys, RP; May, PL, 1991)
"MRI of brain tumors was performed with CPMG pulse sequence, and T1 and T2 relaxation times were measured before and after the administration of 0."	1.28	T1 and T2 relaxation times on gadolinium-diethylenetriaminepentaacetic acid enhanced magnetic resonance images of brain tumors. ( Fujiwara, S; Hishinuma, T; Kubota, R; Matsuzawa, T; Ono, S; Yamada, K; Yamada, S, 1990)
"A distinction between glioblastomas, anaplastic astrocytomas and mixed gliomas is not possible."	1.28	[Contrast medium assisted nuclear magnetic resonance tomography. Signal intensity of gliomatous tumors]. ( Agnoli, AL; Herrmann, S, 1990)
" The MR examination included various plain T1 and T2 weighted spin echo sequences as well as T1 weighted examinations after intravenous application of Gadolinium-DTPA ("Magnevist", Schering AG) in a dosage of 0."	1.28	[Gadolinium-DTPA in magnetic resonance tomography. Clinical use--indications]. ( Imhof, H; Kramer, J; Prayer, L; Stiglbauer, R; Wimberger, D, 1989)
"However, brain tumors, especially intraaxial tumors could often not be differentiated from adjacent tissues on ME images."	1.28	Comparison of multi echo and contrast-enhanced MR scans: image contrast and delineation of intracranial tumors. ( Felix, R; Kornmesser, W; Laniado, M; Schörner, W, 1989)
"The major complication has been seizures."	1.27	Osmotic blood-brain barrier modification: clinical documentation by enhanced CT scanning and/or radionuclide brain scanning. ( Bennett, MJ; Frenkel, EP; Haines, JE; Hill, SA; Howieson, J; Neuwelt, EA; Specht, HD, 1983)
"1986)."	1.27	Non selective transport of [11C-methyl]-L-and D-methionine into a malignant glioma. ( Duden, C; Hundeshagen, H; Meyer, GJ; Müller, JA; Schober, O, 1987)
"All dogs developed brain tumors."	1.27	Magnetic resonance brain tumor imaging in canine glioma. ( Clanton, JA; Kessler, RM; Moore, PM; Tolner, DJ; Whelan, HT; Whetsell, WO, 1987)
" Changes in relaxation times in normal and abnormal tissues following contrast medium, toxicity and dosage of gadolinium-DTPA, and MRI pulse sequence techniques are reviewed."	1.27	Contrast-enhanced magnetic resonance imaging of tumours of the central nervous system: a clinical review. ( Graif, M; Steiner, RE, 1986)
"Primary brain tumors were better visualized with DTPA in four out of five cases (p < 0."	1.26	Differential accumulation of Tc-99m DTPA and Tc-99m pyrophosphate within cerebral and cranial lesions: concise communication. ( Choy, YC; Coupal, JJ; DeLand, FH; Domstad, PA; Kim, EE; Simmons, G, 1980)
"Fifteen cases of brain tumors of supratentorial location were studied by RI cisternography; Cisternographical patterns of decreased or absent radioactivity were classified into five groups as follows: Pattern I: Sharply circumscribed and localized decrease in radioactivity; Pattern II:Ill-defined and focal decrease in radioactivity; Pattern III: Areal decrease in radioactivity involving one whole or two lobes; Pattern IV: Hemispherical decrease in radioactivity and Pattern V: Total decrease in radioactivity in the head."	1.26	[RI cisternography in the diagnosis of brain tumors (author's transl)]. ( Fukumitsu, T; Miwa, Y; Murata, T; Tokuriki, Y, 1977)
"A case of cerebral metastases is presented in which the initial brain scan did not demonstrate the lesion because steroid medication had been started 18 hr earlier."	1.25	Steroid effect on the brain scan in a patient with cerebral metastases. ( Stebner, FC, 1975)

Timeframe	Studies, this research(%)	All Research%
pre-1990	120 (38.34)	18.7374
1990's	175 (55.91)	18.2507
2000's	9 (2.88)	29.6817
2010's	9 (2.88)	24.3611
2020's	0 (0.00)	2.80

Trial	Phase	Enrollment	Study Type	Start Date	Status
SIngle-Stage, Open-Label, Safety and Efficacy Study of Adeno-Associated Virus Encoding Human Aromatic L-Amino Acid Decarboxylase by Magnetic Resonance MR-guided Infusion Into Midbrain in Pediatric Patients With AADC Deficiency[NCT02852213]	Phase 1	31 participants (Anticipated)	Interventional	2016-07-31	Recruiting
Peptide Receptor Radionuclide Therapy (PRRT) in Tumors With High Expression of Somatostatin Receptors[NCT04790708]		250 participants (Anticipated)	Interventional	2018-07-02	Recruiting
Phase I/II Study of Lutathera in Pediatric and Young Adult Patients With Recurrent and/or Progressive High-Grade Central Nervous System Tumors and Meningiomas That Express Somatostatin Type2A Receptors and Demonstrate Uptake on DOTATATE PET[NCT05278208]	Phase 1/Phase 2	65 participants (Anticipated)	Interventional	2022-11-21	Recruiting
The Effect of Alemtuzumab on the Blood-brain-barrier and Cerebral Metabolism in Multiple Sclerosis Patients; a New MRI Method for Treatment Response Evaluation in Multiple Sclerosis[NCT03193086]		35 participants (Anticipated)	Observational	2017-01-01	Recruiting
The Brain Heart Interaction in Acute Stroke[NCT02734082]		204 participants (Actual)	Observational	2013-10-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Basic MR relaxation mechanisms and contrast agent design. Journal of magnetic resonance imaging : JMRI, 2015, Volume: 42, Issue:3 Topics: Animals; Brain; Brain Neoplasms; Collagen; Contrast Media; Diffusion; Drug Design; Fibrin; Gadoliniu	2015
The use of MR contrast in neoplastic disease of the brain. Topics in magnetic resonance imaging : TMRI, 1995,Summer, Volume: 7, Issue:3 Topics: Brain; Brain Diseases; Brain Neoplasms; Contrast Media; Gadolinium; Gadolinium DTPA; Heterocyclic Co	1995
Varix occurring with cerebral venous angioma: a case report and review of the literature. Neuroradiology, 1995, Volume: 37, Issue:1 Topics: Adult; Brain Neoplasms; Cerebral Angiography; Cerebral Veins; Contrast Media; Frontal Lobe; Gadolini	1995
Magnetic resonance imaging of pediatric brain tumors. Topics in magnetic resonance imaging : TMRI, 1993,Summer, Volume: 5, Issue:3 Topics: Adolescent; Brain; Brain Neoplasms; Child; Child, Preschool; Contrast Media; Female; Gadolinium DTPA	1993
[Microanatomy and microsurgery for tumors involving the cavernous sinus]. No shinkei geka. Neurological surgery, 1997, Volume: 25, Issue:5 Topics: Brain; Brain Neoplasms; Carotid Arteries; Cavernous Sinus; Craniotomy; Gadolinium DTPA; Humans; Magn	1997
[Somatostatin receptors in meningioma: diagnostic and therapeutic value]. Revista de neurologia, 1997, Volume: 25, Issue:148 Topics: Antineoplastic Agents, Hormonal; Brain Neoplasms; Chelating Agents; Diagnosis, Differential; Humans;	1997
Somatostatin receptor imaging. Seminars in nuclear medicine, 2002, Volume: 32, Issue:2 Topics: Brain Neoplasms; Breast Neoplasms; Carcinoma, Small Cell; Humans; Indium Radioisotopes; Lung Neoplas	2002
Somatostatin receptor imaging. Seminars in nuclear medicine, 2002, Volume: 32, Issue:2 Topics: Brain Neoplasms; Breast Neoplasms; Carcinoma, Small Cell; Humans; Indium Radioisotopes; Lung Neoplas	2002
Somatostatin receptor imaging. Seminars in nuclear medicine, 2002, Volume: 32, Issue:2 Topics: Brain Neoplasms; Breast Neoplasms; Carcinoma, Small Cell; Humans; Indium Radioisotopes; Lung Neoplas	2002
Somatostatin receptor imaging. Seminars in nuclear medicine, 2002, Volume: 32, Issue:2 Topics: Brain Neoplasms; Breast Neoplasms; Carcinoma, Small Cell; Humans; Indium Radioisotopes; Lung Neoplas	2002
The application of contrast agents in the evaluation of neoplasms of the central nervous system. Topics in magnetic resonance imaging : TMRI, 1992, Volume: 4, Issue:4 Topics: Brain Neoplasms; Cerebellar Neoplasms; Cerebellopontine Angle; Contrast Media; Gadolinium; Gadoliniu	1992
MR imaging of tuberous sclerosis: pathogenesis of this phakomatosis, use of gadopentetate dimeglumine, and literature review. Radiology, 1992, Volume: 183, Issue:1 Topics: Adolescent; Adult; Astrocytoma; Brain; Brain Neoplasms; Child; Child, Preschool; Contrast Media; Dru	1992
CNS imaging of neoplasms. International journal of radiation oncology, biology, physics, 1991, Volume: 21, Issue:3 Topics: Brain Neoplasms; Contrast Media; Gadolinium DTPA; Humans; Magnetic Resonance Imaging; Organometallic	1991
Magnetic resonance imaging diagnosis of an intracranial metastasis of adenocarcinoma of the prostate: case report. Maryland medical journal (Baltimore, Md. : 1985), 1991, Volume: 40, Issue:2 Topics: Adenocarcinoma; Brain Neoplasms; Craniotomy; Diagnosis, Differential; Gadolinium DTPA; Humans; Magne	1991
Rhabdoid tumor of the central nervous system. Medical and pediatric oncology, 1991, Volume: 19, Issue:4 Topics: Antigens, Neoplasm; Brain Neoplasms; Child, Preschool; Combined Modality Therapy; Contrast Media; Fe	1991
Magnetic resonance imaging contrast agents: theory and application to the central nervous system. Journal of neurosurgery, 1990, Volume: 73, Issue:6 Topics: Animals; Brain Diseases; Brain Neoplasms; Contrast Media; Gadolinium DTPA; Humans; Magnetic Resonanc	1990
Gd DTPA: a review of clinical indications in central nervous system magnetic resonance imaging. Radiographics : a review publication of the Radiological Society of North America, Inc, 1989, Volume: 9, Issue:5 Topics: Brain Neoplasms; Central Nervous System Diseases; Contrast Media; Gadolinium; Gadolinium DTPA; Human	1989

Article	Year
[Human testing of the nuclear spin tomographic contrast medium gadolinium-DTPA. Tolerance, contrast affect and the 1st clinical results]. RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1984, Volume: 140, Issue:5 Topics: Adult; Aged; Brain Neoplasms; Clinical Trials as Topic; Contrast Media; Dose-Response Relationship,	1984
[Diagnosis of cerebral metastasis with standard dose gadobutrol vs. a high dose protocol. Intraindividual evaluation of a phase II high dose study]. Der Radiologe, 1995, Volume: 35, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Brain; Brain Neoplasms; Carcinoma, Bronchogenic; Carcinoma, Non-Smal	1995
Brain metastases--comparison of gadodiamide injection-enhanced MR imaging at standard and high dose, contrast-enhanced CT and non-contrast-enhanced MR imaging. Acta radiologica (Stockholm, Sweden : 1987), 1995, Volume: 36, Issue:3 Topics: Adult; Blood-Brain Barrier; Brain Neoplasms; Contrast Media; Female; Gadolinium; Gadolinium DTPA; Hu	1995
Effect of dose and field strength on enhancement with paramagnetic contrast media. AJNR. American journal of neuroradiology, 1994, Volume: 15, Issue:10 Topics: Brain Neoplasms; Cavernous Sinus; Choroid Plexus; Contrast Media; Drug Combinations; Gadolinium DTPA	1994
Brain metastasis of small cell lung carcinoma: comparison of Gd-DTPA enhanced magnetic resonance imaging and enhanced computerized tomography. Japanese journal of clinical oncology, 1994, Volume: 24, Issue:5 Topics: Brain Neoplasms; Carcinoma, Small Cell; Gadolinium DTPA; Humans; Image Enhancement; Lung Neoplasms;	1994
Early postoperative magnetic resonance imaging after resection of malignant glioma: objective evaluation of residual tumor and its influence on regrowth and prognosis. Neurosurgery, 1994, Volume: 34, Issue:1 Topics: Brain Neoplasms; Combined Modality Therapy; Contrast Media; Cranial Irradiation; Female; Follow-Up S	1994
A double blind study to evaluate the tolerability of gadodiamide injection and its effect on renal function in patients undergoing cerebral magnetic resonance imaging. The British journal of radiology, 1993, Volume: 66, Issue:790 Topics: Adult; Aged; Brain Neoplasms; Contrast Media; Double-Blind Method; Female; Gadolinium DTPA; Humans;	1993
Gadodiamide injection as a contrast medium for MRI of the central nervous system: a comparison with gadolinium-DOTA. Neuroradiology, 1993, Volume: 35, Issue:7 Topics: Brain; Brain Neoplasms; Contrast Media; Double-Blind Method; Female; Gadolinium DTPA; Heterocyclic C	1993
Somatostatin receptor imaging in intracranial tumours. European journal of nuclear medicine, 1998, Volume: 25, Issue:7 Topics: Adolescent; Adult; Aged; Brain Neoplasms; Child; Female; Humans; Image Interpretation, Computer-Assi	1998
Gadodiamide injection and gadopentetate dimeglumine. A double-blind study in MR imaging of the CNS. Acta radiologica (Stockholm, Sweden : 1987), 1992, Volume: 33, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Brain Diseases; Brain Neoplasms; Contrast Media; Double-Blind Method	1992
Dosing of Gd-DTPA in MR imaging of intracranial tumors. Magnetic resonance in medicine, 1991, Volume: 22, Issue:2 Topics: Brain Neoplasms; Contrast Media; Female; Gadolinium; Gadolinium DTPA; Humans; Magnetic Resonance Ima	1991
MR evaluation of CNS tumors: dose comparison study with gadopentetate dimeglumine and gadoteridol. Radiology, 1991, Volume: 180, Issue:2 Topics: Adult; Agar; Aged; Brain Neoplasms; Contrast Media; Drug Combinations; Drug Evaluation; Female; Gado	1991
[Optimization of gadolinium-DTPA dose: an inter-individual study of patients with intracranial tumors]. RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1990, Volume: 153, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Contrast Media; Diagnosis, Differential; Female; Ga	1990
Gadodiamide injection: nonionic gadolinium chelate for MR imaging of the brain and spine--phase II-III clinical trial. Radiology, 1990, Volume: 176, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain; Brain Neoplasms; Central Nervous System Diseases;	1990
Central nervous system lesions in pediatric patients: Gd-DTPA-enhanced MR imaging. Radiology, 1988, Volume: 169, Issue:3 Topics: Adolescent; Astrocytoma; Brain Neoplasms; Central Nervous System Diseases; Child; Child, Preschool;	1988
Gd-DTPA: an i.v. contrast agent for clinical MRI. International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1988, Volume: 15, Issue:1 Topics: Brain Neoplasms; Clinical Trials as Topic; Contrast Media; Gadolinium; Gadolinium DTPA; Humans; Inje	1988
Multiple cerebral metastases: detectability with Gd-DTPA-enhanced MR imaging. Radiology, 1987, Volume: 165, Issue:3 Topics: Brain; Brain Neoplasms; Clinical Trials as Topic; Drug Evaluation; False Negative Reactions; False P	1987
Increased detection of intracranial metastases with intravenous Gd-DTPA. Radiology, 1987, Volume: 165, Issue:3 Topics: Adult; Aged; Brain; Brain Neoplasms; Clinical Trials as Topic; Female; Gadolinium; Gadolinium DTPA;	1987
Gadolinium-DTPA in magnetic resonance imaging of the brain. Neurosurgical review, 1987, Volume: 10, Issue:2 Topics: Adult; Aged; Brain; Brain Diseases; Brain Neoplasms; Female; Gadolinium; Gadolinium DTPA; Humans; Ma	1987
Brain scintigraphy in the diagnosis of intracranial lesions. Comparative scanning with 169 ytterbium diethylenetriaminepenta-acetic acid and 203 mercury chlormerodrin. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Feb-10, Volume: 47, Issue:6 Topics: Brain Diseases; Brain Neoplasms; Cerebral Angiography; Chlormerodrin; Costs and Cost Analysis; Drug	1973

pentetic acid and Brain Neoplasms

Research Excerpts

Research

Studies (313)

Authors

Clinical Trials (5)

Trial Overview

Reviews

Trials

Other Studies

Authors	Studies
Rani, N	2
Singh, B	3
Kumar, N	2
Singh, P	1
Hazari, PP	2
Singh, H	1
Kumar, G	1
Radotra, B	1
Kumar, M	1
Bhattacharya, A	1
Sharma, R	1
Kohli, A	1
Chhabra, R	1
Gupta, SK	1
Mishra, AK	2
Chakravarty, R	1
Goel, S	1
Valdovinos, HF	1
Hernandez, R	1
Hong, H	1
Nickles, RJ	1
Cai, W	1
De León-Rodríguez, LM	1
Martins, AF	1
Pinho, MC	1
Rofsky, NM	1
Sherry, AD	1
Sharma, S	1
Watts, A	1
Vyas, S	1
Anish, B	1
Sato, TS	1
Kirby, PA	1
Buatti, JM	1
Moritani, T	1
Bulnes, S	1
Argandoña, EG	1
Bengoetxea, H	1
Leis, O	1
Ortuzar, N	1
Lafuente, JV	1
Hens, M	1
Vaidyanathan, G	1
Zhao, XG	1
Bigner, DD	1
Zalutsky, MR	1
Iqbal, U	1
Albaghdadi, H	1
Nieh, MP	1
Tuor, UI	1
Mester, Z	1
Stanimirovic, D	1
Katsaras, J	1
Abulrob, A	1
Jung, KH	1
Kim, HK	1
Lee, GH	1
Kang, DS	1
Park, JA	1
Kim, KM	1
Chang, Y	1
Kim, TJ	1
On, NH	1
Mitchell, R	1
Savant, SD	1
Bachmeier, CJ	1
Hatch, GM	1
Miller, DW	1
Juweid, ME	1
Menda, Y	1
O'Dorisio, MS	1
Bushnell, D	1
Blake, M	1
Madsen, M	1
Johnson, J	1
Graham, MM	1
HACKER, H	1
SOLOWAY, AH	1
Miyagawa, T	2
Oku, T	2
Sasajima, T	1
Dasai, R	1
Beattie, B	2
Finn, R	2
Tjuvajev, JG	1
Blasberg, R	2
De Stasio, G	1
Rajesh, D	1
Casalbore, P	1
Daniels, MJ	1
Erhardt, RJ	1
Frazer, BH	1
Wiese, LM	1
Richter, KL	1
Sonderegger, BR	1
Gilbert, B	1
Schaub, S	1
Cannara, RJ	1
Crawford, JF	1
Gilles, MK	1
Tyliszczak, T	1
Fowler, JF	1
Larocca, LM	1
Howard, SP	1
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Mehta, MP	1
Pallini, R	1
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Hauser, P	1
Kertész, GP	1
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Constantin, T	1
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Schuler, D	1
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Carr, DH	5
Brown, J	2
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Weinmann, HJ	3
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Thomas, DJ	2
Young, IR	4
Kim, EE	1
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Choy, YC	1
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Maynard, CD	1
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Whitehouse, P	1
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Yamamoto, S	1
Miller, JH	1
Weinblatt, ME	1
Smith, JC	1
Fishman, LS	1
Segall, HD	1
Ortega, JA	1
Shcherbakova, EIa	2
Liass, FM	3
Naumenko, VI	1
Lebedeva, AN	1
Soboleva, OI	1
Cowan, RJ	1
Moody, DM	1
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Specht, HD	1
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Haines, JE	1
Bennett, MJ	1
Hill, SA	1
Frenkel, EP	1
Schörner, W	19
Felix, R	22
Laniado, M	13
Lange, L	1
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Fiegler, W	3
Kazner, E	5
Niendorf, HP	11
Semmler, W	3
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Hall, AS	1
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Marchandise, X	1
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Bourekas, EC	1
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Glass, J	1
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Gruber, ML	1
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Runge, VM	10
Lee, JD	1
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Sivolapenko, G	1
Epenetos, A	1
Stavrou, D	1
Agnoli, AL	2
Herrmann, S	1
Cherryman, G	1
Golfieri, R	1
Kahn, T	2
Fürst, G	2
Roosen, N	2
Steinmetz, H	1
Lenard, HG	2
Göbel, U	2
Bock, WJ	1
Cooley, PA	1
Czarnecki, DJ	1
Sty, JR	1
Tsuchiya, K	1
Makita, K	1
Irie, T	1
Wada, Y	1
Takenaka, E	1
Kaufman, DM	2
Adelman, LS	2
Prayer, L	1
Imhof, H	1
Stiglbauer, R	1
Kramer, J	1
Wimberger, D	1
Norman, AB	1
Thomas, SR	1
Pratt, RG	1
Samaratunga, RC	1
Sanberg, PR	1
Hinshaw, DB	2
Inouye, CT	1
Wong, VC	1
Carollo, BR	1
Wolf, CR	1
Nelson, KL	2
Dickman, CA	1
Rekate, HL	2
Bird, CR	2
Drayer, BP	2
Medina, M	2
Kornmesser, W	2
Cohen, BH	1
Bury, E	1
Packer, RJ	1
Sutton, LN	1
Fang, YX	1
Rieser, GD	1
Just, M	1
Grigat, M	1
Meindl, S	1
Jungke, M	1
Bielke, G	1
Pedrosa, P	1
Voth, D	1
McKinstry, CS	1
Schoerner, W	1
Koehler, D	1
James, AE	1
Peterman, SB	1
Tobias, JS	1
Winterton, R	1
Tobias, M	1
Levin, J	1
Esser, J	1
Savitch, I	1
Springolo, E	1
Vellet, D	1
Gadian, DG	1
Heindel, W	1
Steinbrich, W	1
Friedmann, G	1
Shih, WJ	1
Schober, O	1
Duden, C	1
Meyer, GJ	1
Müller, JA	1
Hundeshagen, H	1
Powers, TA	1
Freeman, MW	1
Robertson, RH	1
Wyatt, SH	1
Whelan, HT	2
Fukunaga, M	1
Otsuka, N	1
Nagai, K	1
Morita, K	1
Muranaka, A	1
Furukawa, T	1
Yanagimoto, S	1
Tomomitsu, T	1
Watanabe, A	1
Bartolozzi, C	1
Olmastroni, M	1
Dal Pozzo, G	1
Petacchi, D	1
Fenzl, G	1
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Fink, U	1
Paajanen, H	1
Määttänen, H	1
Katevuo, K	1
Yoshida, K	1
Furuse, M	1
Kaneoke, Y	1
Sasou, K	1
Motegi, Y	1
Traill, MR	1
Nakamura, T	1
Russell, EJ	1
Geremia, GK	1
Johnson, CE	1
Huckman, MS	1
Ramsey, RG	1
Washburn-Bleck, J	1
Turner, DA	1
Norusis, M	1
Healy, ME	1
Hesselink, JR	1
Press, GA	1
Middleton, MS	1
Rimm, AA	1
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Breger, RK	2
Fisher, ME	1
Papke, RA	1
Hendrix, LE	1
Strother, CM	1
Turski, PA	1
Williams, AL	2
Schaible, TF	1
Goldstein, HA	1
Weinstein, MA	1
Price, AC	1
Wolpert, SM	1
Kaufman, D	2
Stack, JP	1
Antoun, NM	1
Jenkins, JP	1
Metcalfe, R	1
Isherwood, I	1
Miyawaki, M	1
Bussaka, H	1
Wakamatsu, H	1
Asakura, T	1
Uetsuhara, K	1
Flom, RA	1
Hodak, JA	1
Wichmann, W	1
Valavanis, A	1
Haller, D	1
Tsuji, T	1
Kishikawa, T	1
Fujii, K	1
Koga, T	1
De Slegte, RG	1
Crezee, FC	1
Hazenberg, GJ	1
Thjaha, SI	1
Kilgore, DP	1
Daniels, DL	1
Pojunas, KW	1
Berry, I	2
Osaki, L	2
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Murovic, J	2
Norman, D	1
Newton, TH	1
Lin, DS	1
Telepak, RJ	1
Hartshorne, MF	1
Cawthon, MA	1
Bauman, JM	1
Clanton, JA	1
Moore, PM	1
Tolner, DJ	1
Whetsell, WO	1
Girton, M	1
Cohen, PJ	1
Lightman, S	1
Gansow, OA	1
Brechbiel, MW	1
Doppman, JL	1
Jungmann, D	1
Lochner, B	1
Graif, M	1
Takemoto, K	1
Inoue, Y	1
Hashimoto, H	1
Shakudo, M	1
Matsumura, Y	1
Nemoto, Y	1
Fukuda, T	1
Onoyama, V	1
Hakuba, A	1
Yakura, H	1
Bascuas, S	1
Trigo, JE	1
Marin, F	1
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Goldstein, EJ	1
Burnett, KR	1
Wortman, J	1
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Wolfstein, RS	1
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Sakimura, IT	1
Waxman, AD	1
Siemsen, JK	1
Haynie, TP	3
Jansen, CR	1
Meyer, BJ	1
Bieler, EU	1
du Toit, D	1
Waltz, TA	1
Matsen, FA	1
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Eckelman, WC	1
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Hauser, W	1
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Gilday, DL	1
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Hosain, F	3
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Williams, CM	1
Rhodes, BA	1