pentetic acid has been researched along with Amyotrophic Lateral Sclerosis in 2 studies
Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to develop and analyse poly(DL-lactic acid)-methacrylic acid nanospheres bound to the chelating ligand diethylenetriaminepentaacetic acid (DTPA) for the targeted delivery of amantadine in Amyotrophic Lateral Sclerosis (ALS)." | 7.88 | Targeted Delivery of Amantadine-loaded Methacrylate Nanosphere-ligands for the Potential Treatment of Amyotrophic Lateral Sclerosis. ( Choonara, YE; Du Toit, LC; Govender, M; Indermun, S; Kumar, P; Mazibuko, Z; Modi, G; Naidoo, D; Pillay, V, 2018) |
| "This study aimed to develop and analyse poly(DL-lactic acid)-methacrylic acid nanospheres bound to the chelating ligand diethylenetriaminepentaacetic acid (DTPA) for the targeted delivery of amantadine in Amyotrophic Lateral Sclerosis (ALS)." | 3.88 | Targeted Delivery of Amantadine-loaded Methacrylate Nanosphere-ligands for the Potential Treatment of Amyotrophic Lateral Sclerosis. ( Choonara, YE; Du Toit, LC; Govender, M; Indermun, S; Kumar, P; Mazibuko, Z; Modi, G; Naidoo, D; Pillay, V, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mazibuko, Z | 1 |
| Indermun, S | 1 |
| Govender, M | 1 |
| Kumar, P | 1 |
| Du Toit, LC | 1 |
| Choonara, YE | 1 |
| Modi, G | 1 |
| Naidoo, D | 1 |
| Pillay, V | 1 |
| Bartolini, S | 1 |
| Inzitari, D | 1 |
| Castagnoli, A | 1 |
| Amaducci, L | 1 |
2 other studies available for pentetic acid and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Targeted Delivery of Amantadine-loaded Methacrylate Nanosphere-ligands for the Potential Treatment of Amyotrophic Lateral Sclerosis.
Topics: Amantadine; Amyotrophic Lateral Sclerosis; Animals; Antiparkinson Agents; Cells, Cultured; Drug Deli | 2018 |
Correlation of isotopic cisternographic patterns in multiple sclerosis with CSF IgG values.
Topics: Adult; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Female; Humans; Immunoglobulin G; Male; Mid | 1982 |