pentetic acid has been researched along with Alzheimer Disease in 6 studies
Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Over 44 million people live with Alzheimer's disease (AD) worldwide." | 1.46 | A novel class of thiosemicarbazones show multi-functional activity for the treatment of Alzheimer's disease. ( Anjum, R; Bernhardt, PV; Hibbs, D; Kalinowski, DS; Lin, HY; Palanimuthu, D; Poon, R; Richardson, DR; Sahni, S, 2017) |
| "Pretreatment with deferoxamine or diethylenetriaminepentaacetic acid abolishes the ability of the lesions to catalyze the H2O2-dependent oxidation of 3,3'-diaminobenzidine (DAB), strongly suggesting the involvement of associated transition metal ions." | 1.31 | In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: a central role for bound transition metals. ( Harris, PL; Liu, Y; Perry, G; Sayre, LM; Schubert, KA; Smith, MA, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Palanimuthu, D | 1 |
| Poon, R | 1 |
| Sahni, S | 1 |
| Anjum, R | 1 |
| Hibbs, D | 1 |
| Lin, HY | 1 |
| Bernhardt, PV | 1 |
| Kalinowski, DS | 1 |
| Richardson, DR | 1 |
| Rotman, M | 1 |
| Welling, MM | 1 |
| van den Boogaard, ML | 1 |
| Moursel, LG | 1 |
| van der Graaf, LM | 1 |
| van Buchem, MA | 1 |
| van der Maarel, SM | 1 |
| van der Weerd, L | 1 |
| Bartolini, S | 1 |
| Inzitari, D | 1 |
| Castagnoli, A | 1 |
| Amaducci, L | 1 |
| Mattay, VS | 1 |
| Frank, JA | 1 |
| Duyn, JH | 1 |
| Kotrla, KJ | 1 |
| Santha, AK | 1 |
| Esposito, G | 1 |
| Sexton, RH | 1 |
| Barker, P | 1 |
| Sunderland, T | 1 |
| Moonen, CT | 1 |
| Weinberger, DR | 1 |
| Sayre, LM | 1 |
| Perry, G | 1 |
| Harris, PL | 1 |
| Liu, Y | 1 |
| Schubert, KA | 1 |
| Smith, MA | 1 |
| Brusa, G | 1 |
| Claudiani, F | 1 |
| Piccardo, A | 1 |
| Pizio, N | 1 |
| Stoehr, R | 1 |
6 other studies available for pentetic acid and Alzheimer Disease
| Article | Year |
|---|---|
A novel class of thiosemicarbazones show multi-functional activity for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Cell Proliferation; Cell Survival; Crystallography, X-Ray; Dose-Response Relation | 2017 |
Fusion of hIgG1-Fc to 111In-anti-amyloid single domain antibody fragment VHH-pa2H prolongs blood residential time in APP/PS1 mice but does not increase brain uptake.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Blood-Brain Barri | 2015 |
Correlation of isotopic cisternographic patterns in multiple sclerosis with CSF IgG values.
Topics: Adult; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Female; Humans; Immunoglobulin G; Male; Mid | 1982 |
Three-dimensional "BURST" functional magnetic resonance imaging: initial clinical applications.
Topics: Adult; Aged; Alzheimer Disease; Blood Volume; Carotid Stenosis; Cerebellum; Cerebral Cortex; Cerebra | 1996 |
In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: a central role for bound transition metals.
Topics: 3,3'-Diaminobenzidine; Aged; Aged, 80 and over; Alzheimer Disease; Catalysis; Chelating Agents; Copp | 2000 |
Scinticisternography in presenile and senile degenerative disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dementia; Humans; Middle Aged; Pentetic Acid; Tomography | 1990 |