pentamidine has been researched along with Uremia in 5 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 1984, three patients died of severe hypoglycemia after receiving pentamidine isethionate to treat Pneumocystis pneumonia." | 7.67 | Risk factors for hypoglycemia associated with pentamidine therapy for Pneumocystis pneumonia. ( Helmick, CG; Sattler, FR; Stehr-Green, JK; Waskin, H, 1988) |
| "In this prospective study, 26 AIDS patients with 32 episodes of PCP were treated with pentamidine (4 mg/kg/d)." | 5.28 | Higher pentamidine levels in AIDS patients with hypoglycemia and azotemia during treatment of Pneumocystis carinii pneumonia. ( Comtois, R; Gervais, A; Lemieux, C; Pouliot, J; Vinet, B, 1992) |
| "In 1984, three patients died of severe hypoglycemia after receiving pentamidine isethionate to treat Pneumocystis pneumonia." | 3.67 | Risk factors for hypoglycemia associated with pentamidine therapy for Pneumocystis pneumonia. ( Helmick, CG; Sattler, FR; Stehr-Green, JK; Waskin, H, 1988) |
| "In this prospective study, 26 AIDS patients with 32 episodes of PCP were treated with pentamidine (4 mg/kg/d)." | 1.28 | Higher pentamidine levels in AIDS patients with hypoglycemia and azotemia during treatment of Pneumocystis carinii pneumonia. ( Comtois, R; Gervais, A; Lemieux, C; Pouliot, J; Vinet, B, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Comtois, R | 2 |
| Pouliot, J | 2 |
| Gervais, A | 2 |
| Vinet, B | 2 |
| Lemieux, C | 2 |
| Waskin, H | 1 |
| Stehr-Green, JK | 1 |
| Helmick, CG | 1 |
| Sattler, FR | 1 |
| Andersen, R | 1 |
| Boedicker, M | 1 |
| Ma, M | 1 |
| Goldstein, EJ | 1 |
| Navin, TR | 1 |
| Dickinson, CM | 1 |
| Adams, SR | 1 |
| Mayersohn, M | 1 |
| Juranek, DD | 1 |
5 other studies available for pentamidine and Uremia
| Article | Year |
|---|---|
High pentamidine levels associated with hypoglycemia and azotemia in a patient with Pneumocystis carinii pneumonia.
Topics: AIDS-Related Opportunistic Infections; Humans; Hypoglycemia; Male; Middle Aged; Pentamidine; Pneumon | 1992 |
Higher pentamidine levels in AIDS patients with hypoglycemia and azotemia during treatment of Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Adult; Analysis of Variance; Chi-Square Distribution; Female; Hu | 1992 |
Risk factors for hypoglycemia associated with pentamidine therapy for Pneumocystis pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Adult; Amidines; Female; Humans; Hypoglycemia; Infant; Male; Med | 1988 |
Adverse reactions associated with pentamidine isethionate in AIDS patients: recommendations for monitoring therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Amidines; Anemia; Humans; Hypoglycemia; Male; Middle Aged | 1986 |
Effect of azotemia in dogs on the pharmacokinetics of pentamidine.
Topics: Amidines; Animals; Chromatography, High Pressure Liquid; Dogs; Kidney; Kinetics; Male; Pentamidine; | 1987 |