pentamidine has been researched along with Skin Neoplasms in 1 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Skin Neoplasms: Tumors or cancer of the SKIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pentamidine is a small molecule inhibitor of the Ca(+)-binding protein S100B and disrupts the S100B-p53 protein-protein interaction; this is thought to restore wild-type p53 tumour suppressor function in melanoma." | 7.76 | The effect of pentamidine on melanoma ex vivo. ( Cree, IA; Glaysher, S; Knight, LA; Peregrin, K; Smith, J; Stewart, BJ; Weber, DJ, 2010) |
| "Pentamidine is a small molecule inhibitor of the Ca(+)-binding protein S100B and disrupts the S100B-p53 protein-protein interaction; this is thought to restore wild-type p53 tumour suppressor function in melanoma." | 3.76 | The effect of pentamidine on melanoma ex vivo. ( Cree, IA; Glaysher, S; Knight, LA; Peregrin, K; Smith, J; Stewart, BJ; Weber, DJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smith, J | 1 |
| Stewart, BJ | 1 |
| Glaysher, S | 1 |
| Peregrin, K | 1 |
| Knight, LA | 1 |
| Weber, DJ | 1 |
| Cree, IA | 1 |
1 other study available for pentamidine and Skin Neoplasms
| Article | Year |
|---|---|
The effect of pentamidine on melanoma ex vivo.
Topics: Adenosine Triphosphate; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Humans; In Vitro Tec | 2010 |